For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VHALLLARAGIPVVVLEKHNDFLRDFRGDTVHPTTLRIMDELGLIDEFLRLPHTKIDTVAFDTDGSIRTF GNFKVLKRLGFNQPYIAMMPQWDFLDFIAEKASAYPEFTLIRNAEVTDLILEDDRVAGVRTPHDEVRADL VIAADGRKSAVRAAAGLRTAQAHSPMDVLWFRLKWRPGDPRELFGVFRKGLMMAMIYRGDYWQVAYLMPK GASPKGGSLEEFKERIVTAQPRLREHVNDLTSWDDTSELDVRVDRLETWWRTGLLCIGDAAHAMSPAGGV GINLAVADAVAAANILCAPLQQGRVTDRDLAKVQRRRELPTRIVQAVQVLMQDNAIAPNLNGDLSPIHVP KIVGFGPLQAIPPLVVGRGFRPEHVRTPDVHAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4364 | - | - | 100% (384) | hypothetical protein MAV_4364 |
| M. avium 104 | MAV_1804 | mhpA | 2e-09 | 24.29% (317) | 3-(3-hydroxyphenyl)propionate hydroxylase |
| M. avium 104 | MAV_2316 | - | 5e-05 | 24.18% (306) | hypothetical protein MAV_2316 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1780 | - | 3e-83 | 46.89% (386) | hypothetical protein Mb1780 |
| M. gilvum PYR-GCK | Mflv_0304 | - | 8e-80 | 45.74% (387) | hypothetical protein Mflv_0304 |
| M. tuberculosis H37Rv | Rv1751 | - | 2e-83 | 46.89% (386) | hypothetical protein Rv1751 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2614 | - | 1e-164 | 72.51% (382) | hypothetical protein MAB_2614 |
| M. marinum M | MMAR_3394 | - | 1e-100 | 50.52% (388) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4962 | - | 4e-87 | 47.61% (397) | hypothetical protein MSMEG_4962 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3663 | - | 1e-80 | 44.39% (392) | hypothetical protein MUL_3663 |
| M. vanbaalenii PYR-1 | Mvan_0442 | - | 1e-81 | 46.58% (395) | hypothetical protein Mvan_0442 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1780|M.bovis_AF2122/97 MIATMPSMARRSRHDNKITTPAVDCLTIERLDSPASGAPQVTPYARALMG
Rv1751|M.tuberculosis_H37Rv MIATMPSMARRSRHDNKITTPAVDCLTIERLDSPASGAPQVTPYARALMG
Mflv_0304|M.gilvum_PYR-GCK -MR----------DDDTVS-------------------------------
Mvan_0442|M.vanbaalenii_PYR-1 -MRKQLGRPSGSCHHDQMN-------------------------------
MSMEG_4962|M.smegmatis_MC2_155 -MT-----------------------------------------------
MUL_3663|M.ulcerans_Agy99 -MPQPS--------------------------------------------
MAV_4364|M.avium_104 --------------------------------------------------
MAB_2614|M.abscessus_ATCC_1997 -MAQVL--------------------------------------------
MMAR_3394|M.marinum_M -MESEL--------------------------------------------
Mb1780|M.bovis_AF2122/97 ETTTCAIIGGGPAGMVLGLLLARAGVQVTLLEKHGDFLRDFRGDTVHPTT
Rv1751|M.tuberculosis_H37Rv ETTTCAIIGGGPAGMVLGLLLARAGVQVTLLEKHGDFLRDFRGDTVHPTT
Mflv_0304|M.gilvum_PYR-GCK DTTTCAIVGGGPAGMVLGLLLARAGVEVTVLEKHADFLRDFRGDTVHPTT
Mvan_0442|M.vanbaalenii_PYR-1 AKTTCAVVGGGPAGMVLGLLLARAGVEVTVLEKHADFLRDFRGDTVHPTT
MSMEG_4962|M.smegmatis_MC2_155 EKTTCAVVGGGPAGMVLGLLLARAGIEVTVFEKHADFLRDFRGDTVHPAT
MUL_3663|M.ulcerans_Agy99 ETTSVLVAGGGPAGMVLGLLLARAGVDVTVMEKHADFLRDSRGDTVHAST
MAV_4364|M.avium_104 --------------MVHALLLARAGIPVVVLEKHNDFLRDFRGDTVHPTT
MAB_2614|M.abscessus_ATCC_1997 -RTQVCVAGGGPAGLMHALLLARAGINVVVLEKHGDFLRDFRGDTVHPTT
MMAR_3394|M.marinum_M -RARCCVAGGGPAGMMLGYLLARAGVDVIVLEKHADFLRDFRGDTIHPST
:: . ******: * ::*** ***** ****:*.:*
Mb1780|M.bovis_AF2122/97 MRLLDELGLWERFAALPYSEVRTATLHS-NGRAVTYIDFERLHQPY---P
Rv1751|M.tuberculosis_H37Rv MRLLDELGLWERFAALPYSEVRTATLHS-NGRAVTYIDFERLHQPY---P
Mflv_0304|M.gilvum_PYR-GCK LRLLDDLGLWPRFADISHSRLDHATVDVGAGRSVTMVDFRRLRQPH---P
Mvan_0442|M.vanbaalenii_PYR-1 LRLIDELGLWPKFSALPHSRLERATVDVGAGRTITVVDFGRLRQPH---P
MSMEG_4962|M.smegmatis_MC2_155 LRLLDELGLFEKFDALPHSRVERARFDL-GGREVTVVDFGRLNLPH---R
MUL_3663|M.ulcerans_Agy99 LRLLDELGLGSQFAQIPHRLIDTISMKV-QGQPVD-LDLKHLPGAH---Q
MAV_4364|M.avium_104 LRIMDELGLIDEFLRLPHTKIDTVAFDT-DGSIRTFGNFKVLKRLGFNQP
MAB_2614|M.abscessus_ATCC_1997 MRIMDDIGLIDEFLTLPHQKVDHIAFDG-DGQLRTFGDFRALKWLGYKQP
MMAR_3394|M.marinum_M LEVMNELGLYDQLLQRPHQPTPTLNAQF-GSFRALVADFRHLPVRG---K
:.:::::** .: .: . . :: *
Mb1780|M.bovis_AF2122/97 YVAMVPQWDLLNLLAEAAQAEPSFTLRMKTEVTGLLR----EGGKVTGVR
Rv1751|M.tuberculosis_H37Rv YVAMVPQWDLLNLLAEAAQAEPSFTLRMKTEVTGLLR----EGGKVTGVR
Mflv_0304|M.gilvum_PYR-GCK YIAMVPQWDLLNLLADAGRAEPTFTLRMSTEVTGVLR----EGSRVTGVR
Mvan_0442|M.vanbaalenii_PYR-1 YIAMVPQWDLLNLLAEAGEAEPTFTLRMCTEATGLIR----EGGRVVGVR
MSMEG_4962|M.smegmatis_MC2_155 YIALVPQWDFLDLLADAAKEEPTFTLRMQTEVTGLLK----DGDTVTGVR
MUL_3663|M.ulcerans_Agy99 HIALVPQWDFLELLAAAAEAEPTFRLLRSTEVTGVLWGDGPDPGRVVSAT
MAV_4364|M.avium_104 YIAMMPQWDFLDFIAEKASAYPEFTLIRNAEVTDLIL----EDDRVAGVR
MAB_2614|M.abscessus_ATCC_1997 YIAFIPQWDFLDFLAEKAERYPEFTLIRNAEVTDLVL----EGHQVTGVR
MMAR_3394|M.marinum_M FVAMMPQWDFLDFIAKEAQRFSSFRLLMRAEVTKLIE----EPNRVTGVV
.:*::****:*:::* . . * * :*.* :: : *...
Mb1780|M.bovis_AF2122/97 YQGAEG-PGELRAELTVACDGRWSIARHEAGLKAREFPVNFDVWWFKLPR
Rv1751|M.tuberculosis_H37Rv YQGAEG-PGELRAELTVACDGRWSIARHEAGLKAREFPVNFDVWWFKLPR
Mflv_0304|M.gilvum_PYR-GCK YETADG-TGELQAGLTVACDGRGSLLREKTGLRTQEFPVGFDVWWFRLPR
Mvan_0442|M.vanbaalenii_PYR-1 YQDPDG-PGELRADLTVGCDGRGSVLRGLAGLQVREFPVSFDAWWFRLPR
MSMEG_4962|M.smegmatis_MC2_155 YHGPDG-PGELRADLTVACDGRTSRVRKEAGLAPREYPVPFDVGWFRIDR
MUL_3663|M.ulcerans_Agy99 YRAQSGETKHMHADLTVACDGRGSTVRSALGMATRSFGAPMDVWWFRLPR
MAV_4364|M.avium_104 T----P-HDEVRADLVIAADGRKSAVRAAAGLRTAQAHSPMDVLWFRLKW
MAB_2614|M.abscessus_ATCC_1997 S----S-AREVRADVVIAADGRNSAVRAASGLQTASESSPMDVLWFRLNR
MMAR_3394|M.marinum_M VNTPDG-EQKIHSDLVIGCDGRTSTVRAQAGLQVLSLGAPMDVLWFRMSR
.::: :.:..*** * * *: . :*. **::
Mb1780|M.bovis_AF2122/97 -EGDAEFSFLPRFSPGKGLGVIPREGYFQIAYLGPKGTDAQLRERGIEEF
Rv1751|M.tuberculosis_H37Rv -EGDAEFSFLPRFSPGKGLGVIPREGYFQIAYLGPKGTDAQLRERGIEEF
Mflv_0304|M.gilvum_PYR-GCK PETDEMYTLFPRLAPGRAMIVIPREGYLQIALLIEKGTDAALRAHGLDAF
Mvan_0442|M.vanbaalenii_PYR-1 PADDSIYTLVPRIAPGKAMIVIPREGYLQIAMLIPKGTDAERRARGLDAF
MSMEG_4962|M.smegmatis_MC2_155 -IKETAYQLTPRISSGQALILIPREGYFQAGCFLPKGGEKQLHARGLEVF
MUL_3663|M.ulcerans_Agy99 -RPDDPTGLAGIFNSGHGGIAIDRGDYYQIAYIIPKGSDAQLRAQGIEAL
MAV_4364|M.avium_104 -RPGDPRELFGVFRKGLMMAMIYRGDYWQVAYLMPKG--ASPKGGSLEEF
MAB_2614|M.abscessus_ATCC_1997 -RPGDPNESFAVLRRGMLLAMIHRGDYWQVAHLLPKG--TGAQRGSLDAF
MMAR_3394|M.marinum_M -RPGDPEESMGNFGRGAILVLINRGDYWQCGFVIAKGSIEQARRHGVEFF
: * * * .* * . . ** : .:: :
Mb1780|M.bovis_AF2122/97 RRDVSELLPEATASVAALASTDEVKHLNVKVNRLRRWHIDGLLCIGDAAH
Rv1751|M.tuberculosis_H37Rv RRDVSELLPEATASVAALASMDEVKHLNVKVNRLRRWHIDGLLCIGDAAH
Mflv_0304|M.gilvum_PYR-GCK HADVLALLPEAAGTVGSIASLDEVKMLDVKLNRLRCWHIEGMLCIGDAAH
Mvan_0442|M.vanbaalenii_PYR-1 RADVLALLPEAATTIETITSLDDVKHLDVRLNRLRRWHTDGLLFIGDAAH
MSMEG_4962|M.smegmatis_MC2_155 RAQVAEAVPEAS--VDRLTSWDDVKVLDVKLNRLRRWYRDGLLCIGDAAH
MUL_3663|M.ulcerans_Agy99 HRALADLMPWLADRVDALKSFDDVKLLDVQLNRLRRWYCDGALCIGDAAH
MAV_4364|M.avium_104 KERIVTAQPRLREHVNDLTSWDDTSELDVRVDRLETWWRTGLLCIGDAAH
MAB_2614|M.abscessus_ATCC_1997 KKRLVTARPQLREHVDDLHTWDDTSHLDVRVDRLKTWWRPGLLCIGDAAH
MMAR_3394|M.marinum_M REEIVKMAPFVKDRVAEITDFDDLRLLTVSVDRLKQWHRPGLLCIGDAAH
: : * : : *: * * ::**. * * * ******
Mb1780|M.bovis_AF2122/97 AMSPVAGVGINLAVQDAVAAATILAEPLREHRVSSRHLAAVRRRRAFPTA
Rv1751|M.tuberculosis_H37Rv AMSPVAGVGINLAVQDAVAAATILAEPLREHRVSSRHLAAVRRRRAFPTA
Mflv_0304|M.gilvum_PYR-GCK AMSPAGGVGINLAIQDAVAAARLLAEPLRRGTVTGRDLARVRRRRILPTV
Mvan_0442|M.vanbaalenii_PYR-1 AMSPAGGVGINVAIQDAVATARLLADPLRRGAVTERDLAAVRRRRVVPAA
MSMEG_4962|M.smegmatis_MC2_155 AMSPVGGVGINLAIADAVAAARILAEPLRTGRVTRRDLAAVEKRRYVPAA
MUL_3663|M.ulcerans_Agy99 AMSPVGGVGINLALADAVATARMLAPSLRVGRVSTGQLARVQARRWAPTA
MAV_4364|M.avium_104 AMSPAGGVGINLAVADAVAAANILCAPLQQGRVTDRDLAKVQRRRELPTR
MAB_2614|M.abscessus_ATCC_1997 AMSPAGGVGINLAVADAVAAANILVEPLRTGSLSDHHLEAVQRRRELPTK
MMAR_3394|M.marinum_M AMSPIGGVGINLAIQDAVAAANLLISPLRRGQVSDADLQRVQARRELPTR
**** .*****:*: ****:* :* .*: :: .* *. ** *:
Mb1780|M.bovis_AF2122/97 VTQAVQRVLHRRLLGPLLQGRDPTPPAALLGLV----ERLPWLSAVPAYF
Rv1751|M.tuberculosis_H37Rv VTQAVQRVLHRRLLGPLLQGRDPTPPAALLGLV----ERLPWLSAVPAYF
Mflv_0304|M.gilvum_PYR-GCK VTQALQRLIDRRLLGPIVRGGSGGPSPGLIRTV----ERLPWLTVIPAYL
Mvan_0442|M.vanbaalenii_PYR-1 LTQALQRQIDKRFLRPILDGDVTGPPPALVRAI----ERAPWLTFVPAYL
MSMEG_4962|M.smegmatis_MC2_155 VIQAVQRVLHIGLRRALLGGEIRQPPERVLKAVGAVLSRFPGLAKVPAYL
MUL_3663|M.ulcerans_Agy99 FLQGIQRAIHAAIVAVAVTGGPPQPPP-VVRLV----SRSVPVRRIMGYL
MAV_4364|M.avium_104 IVQAVQVLMQDNAIAPNLNGD---LSPIHVPKI----VGFGPLQAIPPLV
MAB_2614|M.abscessus_ATCC_1997 VVQAFQVFLQNNAIEPVLSGD---LSPIKLPFF----VGRWPLKFIPPIA
MMAR_3394|M.marinum_M ATQAVQVFLQKNVVTAVLGSSQQFKAPLPVRLI----RRLPLLARIPARL
*..* :. : . . : . : :
Mb1780|M.bovis_AF2122/97 VGVGVRPEHAPAFARRGPGNRKGP
Rv1751|M.tuberculosis_H37Rv VGVGVRPEHAPAFARRGPGNRKGP
Mflv_0304|M.gilvum_PYR-GCK VGVGVRPERAPRFARRRPQ-----
Mvan_0442|M.vanbaalenii_PYR-1 VGVGVRPERAPEFAKRRPT-----
MSMEG_4962|M.smegmatis_MC2_155 VGVGPLPEHAPDFARRSR------
MUL_3663|M.ulcerans_Agy99 VAIGPLPEHAPKYPRRAR------
MAV_4364|M.avium_104 VGRGFRPEHVRTPDVHAR------
MAB_2614|M.abscessus_ATCC_1997 VGRGLRPERVHTPDVH--------
MMAR_3394|M.marinum_M IGMGVRPEHPDLAVIDKPGPT---
:. * **: