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ATTWILSKGLAAVVTASVAALGLCPGAAADPAAAPQPAPPPNAAPQLPGLPALSQLSPLIQQAATDPQQA TQLLMAAAQAFSHNPTAPTESKNVAAAVNQFVAEPGSPVPNGVTPPDGAPVQHVPATGIEPGLQAHLPTG IDPAHAAGPAPAAAAPSAPAPAATPPSAPAPAAAPAPGPVQPATVPAAAPVPPPPAPAAAAPATPGAPDA APAPAAAPGFGADAPPTQDFMYPSIGTNCLADGSSAIATALSVAGPAKIPAPGPGPGQTAYVFTAVGTPG PAEEQKLPLNVTWVNLTTGKSGTVALKPRPDINPDGPTTLSAIADTGSGSIMSTIFGQVTTKERQCQFMP TIGSTVVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1296 | - | - | 100% (359) | hypothetical protein MAV_1296 |
| M. avium 104 | MAV_4824 | - | 5e-14 | 48.60% (107) | hypothetical protein MAV_4824 |
| M. avium 104 | MAV_3468 | secD | 5e-14 | 46.74% (92) | preprotein translocase subunit SecD |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1188c | - | 1e-146 | 71.54% (369) | hypothetical protein Mb1188c |
| M. gilvum PYR-GCK | Mflv_2151 | - | 1e-117 | 61.19% (353) | hypothetical protein Mflv_2151 |
| M. tuberculosis H37Rv | Rv1157c | - | 1e-146 | 71.54% (369) | hypothetical protein Rv1157c |
| M. leprae Br4923 | MLBr_01506 | - | 1e-127 | 63.56% (376) | hypothetical protein MLBr_01506 |
| M. abscessus ATCC 19977 | MAB_1945c | - | 3e-14 | 27.91% (326) | dihydrolipoamide succinyltransferase |
| M. marinum M | MMAR_4294 | - | 1e-154 | 70.54% (404) | hypothetical protein MMAR_4294 |
| M. smegmatis MC2 155 | MSMEG_5153 | - | 1e-115 | 65.13% (347) | hypothetical protein MSMEG_5153 |
| M. thermoresistible (build 8) | TH_0479 | - | 4e-53 | 90.57% (106) | CONSERVED HYPOTHETICAL ALA-, PRO-RICH PROTEIN |
| M. ulcerans Agy99 | MUL_1004 | - | 1e-153 | 69.61% (408) | hypothetical protein MUL_1004 |
| M. vanbaalenii PYR-1 | Mvan_4552 | - | 1e-107 | 59.17% (360) | hypothetical protein Mvan_4552 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2151|M.gilvum_PYR-GCK --------MSTTGSKAMTKTRLTTALAVCSSAVLLTVGVVGPANADP-TA
Mvan_4552|M.vanbaalenii_PYR-1 --------MS-------TRTTLTTTLAVCSSVALLTVGVTGVAHADP-TA
MMAR_4294|M.marinum_M ---------------MASTWSLSKGLAAVVVTSAAAFGLCPGAAADP-AA
MUL_1004|M.ulcerans_Agy99 ---------------MASTWSLSKGLAAVVVTSAAAFGLCPAAAADP-AA
MAV_1296|M.avium_104 ---------------MATTWILSKGLAAVVTASVAALGLCPGAAADPAAA
Mb1188c|M.bovis_AF2122/97 -MRRLTNTEHRENTTVASTWSVCKGLAAVVITSAAAFALCPNAAADP-AT
Rv1157c|M.tuberculosis_H37Rv -MRRLTNTEHRENTTVASTWSVCKGLAAVVITSAAAFALCPNAAADP-AT
MLBr_01506|M.leprae_Br4923 ---------MKTGGFVTSAWNLPKGLVAVVTASTAAFGLCQNAAADP-AN
TH_0479|M.thermoresistible__bu --------------------------------------------------
MSMEG_5153|M.smegmatis_MC2_155 ----------------MSPKTFLATAAAIGSSAALLLG-TGIAHADP--G
MAB_1945c|M.abscessus_ATCC_199 MAFSVQMPALGESVTEGTVTRWLKQEGDTVEVDEPLLEVSTDKVDTEIPA
Mflv_2151|M.gilvum_PYR-GCK PLPAPLPIDGLQAPGLPAVQSLGPVIQQAASDPTNAASMLMAAAAVFAGD
Mvan_4552|M.vanbaalenii_PYR-1 PLP----IDGMQAPGLPAVQSLGPVIQQAASDPTNAASMLMAAAAVFAGD
MMAR_4294|M.marinum_M PQPNP----NPQLPGLPALAQLSPIIQQAAGNPEQATQLLMAAAQAFAHN
MUL_1004|M.ulcerans_Agy99 PQPNP----NPQLPGLPALAQLSPIIQQAAGNPEQATQLLMAAAQAFAHN
MAV_1296|M.avium_104 PQPAPPPNAAPQLPGLPALSQLSPLIQQAATDPQQATQLLMAAAQAFSHN
Mb1188c|M.bovis_AF2122/97 PQPNP----TQQLPGLPALAQLSPIIQQAAMNPAQATQLLMAAASAFAGN
Rv1157c|M.tuberculosis_H37Rv PQPNP----TQQLPGLPALAQLSPIIQQAAMNPAQATQLLMAAASAFAGN
MLBr_01506|M.leprae_Br4923 PYGTPP-NPTQQLPGLPALAQLSPIVQQAANNPQQATQLLMEAVSALTQN
TH_0479|M.thermoresistible__bu --------------------------------------------------
MSMEG_5153|M.smegmatis_MC2_155 PLPID----AAQAPGLSAVQGLSPVIQQAAADPAGAAQLLMAAAQAFAAN
MAB_1945c|M.abscessus_ATCC_199 PTSGVLTKIVAREDDTVEIGGELGVISEAGEAAPAAPAPAPAPAAAPAPE
Mflv_2151|M.gilvum_PYR-GCK MAAPKPSRDVASAVNQFVAQP-----------------------------
Mvan_4552|M.vanbaalenii_PYR-1 MAAPQPSRDVASAVNQFVAQP-----------------------------
MMAR_4294|M.marinum_M PAAPTESRNVASSVNQFVQEPVNPAPGSPPLGVPA---PAAAPVEVAPPA
MUL_1004|M.ulcerans_Agy99 PAAPTESRNVASSVNQFVQEPVNPAPGSPPLGVPA---PAAAPVEVAPPA
MAV_1296|M.avium_104 PTAPTESKNVAAAVNQFVAEPGSPVPNG-----------------VTPPD
Mb1188c|M.bovis_AF2122/97 PAVPTESKNVASSVNQFVAEPTNPDSAALG---------VPAPHGVALPE
Rv1157c|M.tuberculosis_H37Rv PAVPTESKNVASSVNQFVAEPTNPDSAALG---------VPAPHGVALPE
MLBr_01506|M.leprae_Br4923 PTAPIASKNLATSVSQFMQEPNNPNPGASALDIPTSGVPAPAANGITPLD
TH_0479|M.thermoresistible__bu --------------------------------------------------
MSMEG_5153|M.smegmatis_MC2_155 KTEPADSRNVATAVNQFVAEPLTATP------------------------
MAB_1945c|M.abscessus_ATCC_199 PTPAPAPEATATAAPEPAAEPPAAAAPAGSG-----TSVKMPELGESVTE
Mflv_2151|M.gilvum_PYR-GCK ---VAHVPATGAVPGFEA------------HLPAGVDPRHVLGPAPEAVP
Mvan_4552|M.vanbaalenii_PYR-1 ---VAHVPATGAVPGAEA------------HLPAGVNPEHVLGPAPEALP
MMAR_4294|M.marinum_M SAPVPHVPAPGAEPGTLA------------HLPAGIDPAHAAGPAPVAAP
MUL_1004|M.ulcerans_Agy99 SAPVPHVPAPGAEPGTLA------------HLPAGIDPAHAAGPAPVAAP
MAV_1296|M.avium_104 GAPVQHVPATGIEPGLQA------------HLPTGIDPAHAAGPAPAAA-
Mb1188c|M.bovis_AF2122/97 AIPVPHVPPLGAEPGVQA------------HLPTGIDPSHAAGPAPAVA-
Rv1157c|M.tuberculosis_H37Rv AIPVPHVPPLGAEPGVQA------------HLPTGIDPSHAAGPAPAVA-
MLBr_01506|M.leprae_Br4923 VVLVPHLPSAGAEPGAQA------------HLPTGIDPVHAAGPATAAT-
TH_0479|M.thermoresistible__bu --------------------------------------------------
MSMEG_5153|M.smegmatis_MC2_155 ----EHIPAAG--AGLDA------------HLPAGIDPAHAVGPAEALPP
MAB_1945c|M.abscessus_ATCC_199 GTVTRWLKKVGDEVGVDEPLVEVSTDKVDTEIPSPVAGVLLSISANEDDT
Mflv_2151|M.gilvum_PYR-GCK QALP----EVAHAPAAAAAPG--PAPAPGPAPEVATPVAAPVADPAAPAA
Mvan_4552|M.vanbaalenii_PYR-1 QALPQALPEVAHAPAAAAAPG--PAPAPGPAPAPGAEVATPVAAPAAPG-
MMAR_4294|M.marinum_M AGAPPASAPAPAAAAPASAPGTAPAPAAAPGPAPAAPAPAPAAAAPAPAP
MUL_1004|M.ulcerans_Agy99 AGAPPASAPAPAAAAPASAPGTAPAPAAAPGPAPAAPAPAPAAAAPAPAP
MAV_1296|M.avium_104 ---------APSAPAPAATPPSAPAPAAAPAPGPVQPATVPAAAPVPPPP
Mb1188c|M.bovis_AF2122/97 ----------PTVTPPVAAP---PASAPAPAPDAAQPVAVPGPPPAPPAP
Rv1157c|M.tuberculosis_H37Rv ----------PTVTPPVAAP---PASAPAPAPDAAQPVAVPGPPPAPPAP
MLBr_01506|M.leprae_Br4923 -----------------------PTPGSPTNRTAAPPTPVASPAPTTP--
TH_0479|M.thermoresistible__bu --------------------------------------------------
MSMEG_5153|M.smegmatis_MC2_155 AAEP------LAAPAPAPAPEAAPAPAPEAAPAPAPEAAAPAPEAPAPAP
MAB_1945c|M.abscessus_ATCC_199 VAVGGELAVVGAADAAPAAPAAPAAPAPEPAAAPAAAAAPPAPPAPAPAP
Mflv_2151|M.gilvum_PYR-GCK APVTP-----------------------------------AANPAGAPGL
Mvan_4552|M.vanbaalenii_PYR-1 ------------------------------------------------GL
MMAR_4294|M.marinum_M APAAPPAAPVAA----PAPVPAPAPAAAPAPEAAAPAPAPAPAPAAAPGF
MUL_1004|M.ulcerans_Agy99 APAAPPAAPVAAPVAAPAPVPAPAPAAAPAPEAAAPAPAPAPAPAAAPGF
MAV_1296|M.avium_104 APAA-------------------AAPATPG------APDAAPAPAAAPGF
Mb1188c|M.bovis_AF2122/97 RAAAP------------------APASAA--------PAPAAAPAPASGF
Rv1157c|M.tuberculosis_H37Rv RAAAP------------------APASAA--------PAPAAAPAPASGF
MLBr_01506|M.leprae_Br4923 -----------------------------------------ELPATTPGF
TH_0479|M.thermoresistible__bu --------------------------------------------------
MSMEG_5153|M.smegmatis_MC2_155 ----------------------------------------APAAAAAPGF
MAB_1945c|M.abscessus_ATCC_199 AAPAP-----------------------------------ASTAPAANGA
Mflv_2151|M.gilvum_PYR-GCK GPNAPVTQDFLYPSISNG---------CLSDGGNVLATAISVAGPATIPL
Mvan_4552|M.vanbaalenii_PYR-1 GPNAPVTQDFLYPSISNG---------CLSDGGNVLATAISVAGPATIPL
MMAR_4294|M.marinum_M GPDAPPTQDFMYPSIGTN---------CLADGSNIIATALSVAGPATIPT
MUL_1004|M.ulcerans_Agy99 GPDAPPTQDFMYPSIGTN---------CLADGSNIIATALSVAGPATIPT
MAV_1296|M.avium_104 GADAPPTQDFMYPSIGTN---------CLADGSSAIATALSVAGPAKIPA
Mb1188c|M.bovis_AF2122/97 GADAPPTQDFMYPSIGPN---------CVADGSNSIATALSVAGPAKIPL
Rv1157c|M.tuberculosis_H37Rv GADAPPTQDFMYPSIGPN---------CVADGSNSIATALSVAGPAKIPL
MLBr_01506|M.leprae_Br4923 GPDAPPTQDFIYPSISTN---------CLADGSSSIATALSVAGPAKIPL
TH_0479|M.thermoresistible__bu -----------------------------------------VAGPADIPT
MSMEG_5153|M.smegmatis_MC2_155 GPDAPVTQEFMYPSISNG---------CLADGGNVLATAISVAGPATIPL
MAB_1945c|M.abscessus_ATCC_199 AGDNPYVTPLVRKLAAENNVDLSALSGSGVGGRIRKQDVLAAAEAAKAPA
.* .* *
Mflv_2151|M.gilvum_PYR-GCK PGPGPGQTAYVFTAIGTPGPAAEQKLPLNATWVNLTTGKSGSVTLKPRPD
Mvan_4552|M.vanbaalenii_PYR-1 PGPGPGQTAYVFTAIGTPGPAAEQKLPLNATWVNLTTGKSGSVTLKPRPD
MMAR_4294|M.marinum_M PGPGPGQTAYVFTAVGTPGPAEVQRLPLNVTWVNLTTGKSGSVTLKPRSD
MUL_1004|M.ulcerans_Agy99 PGPGPGQTAYVFTAVGTPGPAEVQRLPLNVTWVNLTTGKSGSVTLKPRSD
MAV_1296|M.avium_104 PGPGPGQTAYVFTAVGTPGPAEEQKLPLNVTWVNLTTGKSGTVALKPRPD
Mb1188c|M.bovis_AF2122/97 PGPGPGQTAYVFTAVGTPGPADVQRLPLNVTWVNLTTGKSGSATLRPRSD
Rv1157c|M.tuberculosis_H37Rv PGPGPGQTAYVFTAVGTPGPADVQRLPLNVTWVNLTTGKSGSATLRPRSD
MLBr_01506|M.leprae_Br4923 PGPGPGQAAYVFTAVGTPGPADVQKLPLNVTWVNLTTGKSGSATLKPRPD
TH_0479|M.thermoresistible__bu PGPGPGQTAYVFTAVGTPGPAPEQKLPLNVTWVNLTTGKSGTATLKPRPD
MSMEG_5153|M.smegmatis_MC2_155 PGPGPGQTAYVFTAIGTPGPAAEQKLPLNVTWVNLTTGKSGSATLKTRPD
MAB_1945c|M.abscessus_ATCC_199 AAPAPAAPAASAPAAVAPSLAHLRGTTQKANRIRQITAKKTRESLQETAQ
..*.*. .* .* :*. * : . :.. :. *.*. :*: .:
Mflv_2151|M.gilvum_PYR-GCK MNPNGPTTLTAIADTGS---------------------------------
Mvan_4552|M.vanbaalenii_PYR-1 MNPNGPTTLTAIADTGS---------------------------------
MMAR_4294|M.marinum_M INPEGPTTLTGIADTGS---------------------------------
MUL_1004|M.ulcerans_Agy99 INPEGPTTLTGIADTGS---------------------------------
MAV_1296|M.avium_104 INPDGPTTLSAIADTGS---------------------------------
Mb1188c|M.bovis_AF2122/97 INPDGPTTLTVIADTGS---------------------------------
Rv1157c|M.tuberculosis_H37Rv INPDGPTTLTVIADTGS---------------------------------
MLBr_01506|M.leprae_Br4923 INPEGPTTLTVIADTGS---------------------------------
TH_0479|M.thermoresistible__bu INPDGPTTLTAIVDTGS---------------------------------
MSMEG_5153|M.smegmatis_MC2_155 LNPEGPTTLTAIADTGS---------------------------------
MAB_1945c|M.abscessus_ATCC_199 LTQTHEVDVTKIAALRARAKAAFAEREGVNLTFLPFFAKAAVEALKTHPN
:. . :: *. :
Mflv_2151|M.gilvum_PYR-GCK ---------------------------GSIMSTVFG--------------
Mvan_4552|M.vanbaalenii_PYR-1 ---------------------------GSIMSTIFG--------------
MMAR_4294|M.marinum_M ---------------------------GSIMSTIFG--------------
MUL_1004|M.ulcerans_Agy99 ---------------------------GSIMSTIFG--------------
MAV_1296|M.avium_104 ---------------------------GSIMSTIFG--------------
Mb1188c|M.bovis_AF2122/97 ---------------------------GSIMSTIFG--------------
Rv1157c|M.tuberculosis_H37Rv ---------------------------GSIMSTIFG--------------
MLBr_01506|M.leprae_Br4923 ---------------------------GSIMSTIFG--------------
TH_0479|M.thermoresistible__bu ---------------------------GSIMSTIFG--------------
MSMEG_5153|M.smegmatis_MC2_155 ---------------------------GSIISTIFG--------------
MAB_1945c|M.abscessus_ATCC_199 VNASYNEESKEITYFDAEHLGIAVDTDQGLLSPVIHNAGDLSLAGLARAI
.::*.::
Mflv_2151|M.gilvum_PYR-GCK -QVTTTEKQCQFMP-----------TIGS--------TVVP---------
Mvan_4552|M.vanbaalenii_PYR-1 -QVTTTEKQCQFMP-----------TIGS--------TVVP---------
MMAR_4294|M.marinum_M -QVTTKERQCQFMP-----------TIGS--------TVVP---------
MUL_1004|M.ulcerans_Agy99 -QVTTKERQCQFMP-----------TIGS--------TVVP---------
MAV_1296|M.avium_104 -QVTTKERQCQFMP-----------TIGS--------TVVP---------
Mb1188c|M.bovis_AF2122/97 -QVTTKDRQCQFMP-----------TIGS--------TVVP---------
Rv1157c|M.tuberculosis_H37Rv -QVTTKDRQCQFMP-----------TIGS--------TVVP---------
MLBr_01506|M.leprae_Br4923 -QVTTKEKQCQFMP-----------TIGS--------TVVP---------
TH_0479|M.thermoresistible__bu -QVTTVDKQCQFMP-----------TIGS--------TVVP---------
MSMEG_5153|M.smegmatis_MC2_155 -QVTTTEKQCQFMP-----------TIGS--------TVVP---------
MAB_1945c|M.abscessus_ATCC_199 ADIAARARSGNLKPDELAGGTFTITNIGSQGALFDTPILVPPQAAMLGTG
:::: :. :: * .*** :**
Mflv_2151|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4552|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4294|M.marinum_M --------------------------------------------------
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
MAV_1296|M.avium_104 --------------------------------------------------
Mb1188c|M.bovis_AF2122/97 --------------------------------------------------
Rv1157c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01506|M.leprae_Br4923 --------------------------------------------------
TH_0479|M.thermoresistible__bu --------------------------------------------------
MSMEG_5153|M.smegmatis_MC2_155 --------------------------------------------------
MAB_1945c|M.abscessus_ATCC_199 AIVKRPRVIRDDAGNESIGIRSVCYLPLTYDHRLIDGADAGRFLTTIKHR
Mflv_2151|M.gilvum_PYR-GCK ------------
Mvan_4552|M.vanbaalenii_PYR-1 ------------
MMAR_4294|M.marinum_M ------------
MUL_1004|M.ulcerans_Agy99 ------------
MAV_1296|M.avium_104 ------------
Mb1188c|M.bovis_AF2122/97 ------------
Rv1157c|M.tuberculosis_H37Rv ------------
MLBr_01506|M.leprae_Br4923 ------------
TH_0479|M.thermoresistible__bu ------------
MSMEG_5153|M.smegmatis_MC2_155 ------------
MAB_1945c|M.abscessus_ATCC_199 LEEGAFEADLGL