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M. avium 104 MAV_3653 (-)

annotation: glycosyltransferase GtfE
coordinates: 3779447 - 3780676
length: 409

LLSAYDSRGGVQPLAALAVQLRALGVDARVSAPPDAEFAELLARAGVPLVAFGDSLRAMKTAATTPSEEQ
LRRQLDGLIAAQFDAAAAARECDALVVAGFPPAAAAARSAAEKRGAHYVYVSYQPTILPSPHYPPPGYAD
AAIDNRLLWQLDGRDNRLLWQLDGRYMQALFGETLNARRASIGLPPLDDLRGYALTERPWLATDPTLDPW
RPPGDLDVVQTGAWLLADDRRLPAELDAFLDAGAPPVYVGFGSMPMRACRDVARVAIEAVRAQRRRAVVS
RGWAGLGPIDDGEDCLVVGEVNHQALFGRVAAVVHHGGVGTLTAAALAGAPQVVVPQGADQPYWAARVAE
LGIGAAHDGPAPTVESLSAVLGTALTERTRARAGAVAATIRTDGAARAARLLVARLAG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_3653--100% (409)glycosyltransferase GtfE
M. avium 104MAV_2747-5e-2727.67% (412) rhamnosyltransferase RtfA
M. avium 104MAV_3258-4e-2526.81% (429) glycosyltransferase family protein 28

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1551-3e-2427.00% (426) glycosyltransferase
M. gilvum PYR-GCKMflv_2592-1e-0725.54% (415) glycosyl transferase family protein
M. tuberculosis H37RvRv1524-3e-2427.00% (426) glycosyltransferase
M. leprae Br4923MLBr_02348-1e-2929.07% (399) putative glycosyl transferase
M. abscessus ATCC 19977MAB_4686-2e-2539.51% (205) glycosyltransferase
M. marinum MMMAR_0148-5e-3230.02% (433) glycosyltransferase
M. smegmatis MC2 155MSMEG_4740-1e-2927.19% (423) glycosyltransferase family protein 28
M. thermoresistible (build 8)TH_1989-3e-1538.28% (128) Glycosyltransferase family protein 28
M. ulcerans Agy99MUL_4949-2e-3129.56% (433) glycosyltransferase
M. vanbaalenii PYR-1Mvan_4035-1e-0725.70% (428) glycosyl transferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


MAV_3653|M.avium_104                ------MLLSAYDSRGGVQPLAALAVQLRALGVDARVSAPPDAEFAELLA
MAB_4686|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1551|M.bovis_AF2122/97            ----MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETA
Rv1524|M.tuberculosis_H37Rv         ----MKFVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETA
MLBr_02348|M.leprae_Br4923          ----MKFTLAASGSRGDVEPFAALGLELQRRGHEVRIGVPPDMLRFVESA
MMAR_0148|M.marinum_M               ----MKAVVASYGSRGDVEPCAAAARELLRRGHEVRVAAPPNLVGFLESA
MUL_4949|M.ulcerans_Agy99           ----MKAVVASYGSRGDVEPCAAAARELLRRGHEVRVAAPPNLVGFLESA
MSMEG_4740|M.smegmatis_MC2_155      ----MKFVVAIHGTRGDIEPSATVATELRRRGHEVRMAVPPNLVPFVERI
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK          MNAMPDILITACPPVGHIGPLLNVAHGLVAHGHRVTVLTSARHADKIRAV
Mvan_4035|M.vanbaalenii_PYR-1       ---MAAVLIAVLSPVGHVEPLFAVAEDLVSRGDQVTVMTGAAHTDSIRAI
                                                                                      

MAV_3653|M.avium_104                RAGVPLVAFGDSLRAMKTAATTPSEEQLRRQLDGLIAAQFDAAAAARECD
MAB_4686|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1551|M.bovis_AF2122/97            GLSAVAYGSRDSQEQ--LDEQFLHNAWKLQNPIKLLREAMAPVTEGWAEL
Rv1524|M.tuberculosis_H37Rv         GLSAVAYGSRDSQEQ--LDEQFLHNAWKLQNPIKLLREAMAPVTEGWAEL
MLBr_02348|M.leprae_Br4923          GLAAVAYGP-DTQEF--LARDTYS-QWRQWWKILPPIKALQQLRQAWADM
MMAR_0148|M.marinum_M               GLTTVAYGPDSHQQMGPAANLVGDFAATAQHPITMVPKLIEHLTRVNAAK
MUL_4949|M.ulcerans_Agy99           GLTTVAYGPDSHQQMGPAPNLVGDLAATAQHPITMVPKLIEHLTRVNAAK
MSMEG_4740|M.smegmatis_MC2_155      GLSAESYGVDSQQQL---DADTFRDFWKIRNPVKAIREGREYMVGGWAEM
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK          GADPRPLPYGADYDDARLDADLPGRAHTSGIARINFDVEHVFVRPMPYQF
Mvan_4035|M.vanbaalenii_PYR-1       GAHPHPLPRYADFDDAPFDTGQ--RAATSGIDALSRAVIRLFLTPMPLQA
                                                                                      

MAV_3653|M.avium_104                ALVVAGFPPA-AAAARSAAEKRGAHYVYVSYQPTILPSPHYPPPGYADAA
MAB_4686|M.abscessus_ATCC_1997      -------------MPRPAG-----------WRP-----------------
Mb1551|M.bovis_AF2122/97            SAMLTPVAAG-ADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRANGEI
Rv1524|M.tuberculosis_H37Rv         SAMLTPVAAG-ADLLLTGQIYQEVVANVAEHHGIPLAALHFYPVRANGEI
MLBr_02348|M.leprae_Br4923          ATDLKSLADG-ADLVMTGVVYQGVVANVAEYYGIPFGVLHFVPARVNGKI
MMAR_0148|M.marinum_M               SETLTALADG-ADLLVVGFNEQAVAANVAEYFGIPLAGLHFFPAPA----
MUL_4949|M.ulcerans_Agy99           SETLTALADG-ADLLVVGFNEQAVAANVAEYFGIPLAGLHFFPAPA----
MSMEG_4740|M.smegmatis_MC2_155      SATVAALADG-ADVLLTGTTYQEVVANVAESERIPLAALHYFPHRANSQI
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK          SAVQELLAANSFDAVITDAFFLGVIPLLLDPTLARPPIMAYSTTPLFLSS
Mvan_4035|M.vanbaalenii_PYR-1       AELRRALADRHYDAVIVDYLFLGILPLLLDDTVRTPPVLHYTPTPMMLSS
                                                                                      

MAV_3653|M.avium_104                ID-----NRLLWQLDGRDNRLLWQLDGRYMQALFGETLNARRASIGLPPL
MAB_4686|M.abscessus_ATCC_1997      --------------------------------------------------
Mb1551|M.bovis_AF2122/97            AFPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRM
Rv1524|M.tuberculosis_H37Rv         AFPARLPAPLVRSTITAIDWLYWRMTKGVEDAQRRELGLPKASTPAPRRM
MLBr_02348|M.leprae_Br4923          IP--SLPSPLNRAILATVWRAHWLLAKKPEDAQRRELGLPKATSLSTRRI
MMAR_0148|M.marinum_M               -----LPAGMLST----------LATKAADDAQRQALGLPPALESVPQRV
MUL_4949|M.ulcerans_Agy99           -----LPAGMLST----------LATKAADDAQRQALGLPPASESVPQRV
MSMEG_4740|M.smegmatis_MC2_155      LP-IRLPRRIVEPMWAVAEWGYWQILKSAEDAQRRELGLAPARSSSVNRI
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK          RDTAPAGPGILPMPGAVGRLRNRLLGLLSRAVLLRPAHRSAERMLRAMGL
Mvan_4035|M.vanbaalenii_PYR-1       RDTAPVGLGLPPARTAARRALYRALTLLSQKVLLRNAQRTADRMLTSMGV
                                                                                      

MAV_3653|M.avium_104                DDLRGYALTE------RPWLATDPTLDPWRPPGDLDVVQTGAWLLADDRR
MAB_4686|M.abscessus_ATCC_1997      ----GLEICG------YWWPQTDP---QWRP-------------------
Mb1551|M.bovis_AF2122/97            AVRGSLEIQA------YDALCFPGLAAEW---GGRRPFVG-ALTMESATD
Rv1524|M.tuberculosis_H37Rv         AVRGSLEIQA------YDALCFPGLAAEW---GGRRPFVG-ALTMESATD
MLBr_02348|M.leprae_Br4923          VKRGALEIQA------YDELCFPGLAAEWAEYGDRRPFVG-ALTLELPTA
MMAR_0148|M.marinum_M               AEQGSLEIQA------YDQIVLPGPPGRWVQADGRHPFVG-ALTLQSPTD
MUL_4949|M.ulcerans_Agy99           AEQGSLEIQA------YDQIVLPGPPGRWVQADGRHPFIG-ALTLQSPTD
MSMEG_4740|M.smegmatis_MC2_155      VSSGTLEIQA------YDEVFFPGLRQEWR---GTRPFVG-ALTLELPTD
TH_1989|M.thermoresistible__bu      --------------------------------------------------
Mflv_2592|M.gilvum_PYR-GCK          PDLPVFVLECAILADRVIVPTVPDFEYPRRDLPAHVRFVGAVSPLPGDDF
Mvan_4035|M.vanbaalenii_PYR-1       PRLPVPLLDAGRLADRLIVPTVPSFEYPRSDLPEGVRFVGLVRPRSADRF
                                                                                      

MAV_3653|M.avium_104                LPAELDAFLDAGAPPVYVGFGS--MPMRACRDVARVAIEAVRAQRRRAVV
MAB_4686|M.abscessus_ATCC_1997      -DAALVDFLRAGPPPVYVGFGSTMTSAKQSEHISQLVRSALRRAGVRGIV
Mb1551|M.bovis_AF2122/97            ADDEVASWIAADTPPIYFGFGS--MPIGSLADRVAMISAACAELGERALI
Rv1524|M.tuberculosis_H37Rv         ADDEVASWIAADTPPIYFGFGS--MPIGSLADRVAMISAACAELGERALI
MLBr_02348|M.leprae_Br4923          ADNEVLSWIAAGTPPIYFGFGS--MPIVSPTDTVAMIAAACADLGERALI
MMAR_0148|M.marinum_M               DDDAILAWIAEGAPPIYFGFGS--TPLTSPAEQFAMISAACAQLGERALI
MUL_4949|M.ulcerans_Agy99           DDDAILAWIAEGAPPIYFGFGS--TPLTSPAEQFAMISAACAQLGERALI
MSMEG_4740|M.smegmatis_MC2_155      TDDDVTAWAASGKPPIYFGFGS--MPVQSPADAVTMISSVCTRLGERALI
TH_1989|M.thermoresistible__bu      -----------------------------------MFASVCSRLGERALI
Mflv_2592|M.gilvum_PYR-GCK          IAPAWWGELYRGRPVVHVTQGT--VDNADLTRLIEPTIEALAGEDVTVVV
Mvan_4035|M.vanbaalenii_PYR-1       VTPPWWEVLDADRPVVHVTQGT--VDNRDLSRLIEPTITALADTDVTVVV
                                                                           .        ::

MAV_3653|M.avium_104                SRGWA--GLGPIDDGEDCLVVGEVNHQALFGRVAAVVHHGGVGTLTAAAL
MAB_4686|M.abscessus_ATCC_1997      QAGWA--GIDVGD--ETTLTVTEVPHRWLFPHVAAVVHHCGAGTTAAGLR
Mb1551|M.bovis_AF2122/97            CSGPS--DATGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLR
Rv1524|M.tuberculosis_H37Rv         CSGPS--DATGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLR
MLBr_02348|M.leprae_Br4923          SVKPK--DLTQVPKFDHVKIVTSVSHAAVFPACRAVVHHGGAGTTAASLR
MMAR_0148|M.marinum_M               CAGPN--DFGQMPHSHQVMVAPAVNHAAVFPACRAIVHHGGAGTTAAGLR
MUL_4949|M.ulcerans_Agy99           CAGPN--DFGQMPHSHQVMVAPAVNHAAVFPACRAIVHHGGAGTTAAGLR
MSMEG_4740|M.smegmatis_MC2_155      SSGAW--NLDAIPESDHVKVVGAVNHAKIFPLCRAVVHHGGAGTTAAGLR
TH_1989|M.thermoresistible__bu      CAGGT--DIDGVPEYGHVKVVGAVNYARVFPACRAIVHHGGSGTTAAVLR
Mflv_2592|M.gilvum_PYR-GCK          STGGRPVSQIRTPLPANTFVAEFLPHDVLLPLVDVLVTNGGYGAVQRALA
Mvan_4035|M.vanbaalenii_PYR-1       STGGRTRDSIRVPIPANTHVCEYIPHDRLLPKVDVMVTNGGYGGVQRALA
                                           .               : :  ::    .:* : * *       

MAV_3653|M.avium_104                AGAPQVVVPQGADQPYWAARVAELGIGAAHDGP-APTVESLSAVLGTALT
MAB_4686|M.abscessus_ATCC_1997      AGVPTVAVPGLGDQPFWARRLRDLGLSADTVPQRTLTVERLAAAIRTAVT
Mb1551|M.bovis_AF2122/97            AGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFS-SATKESLIADLRTILA
Rv1524|M.tuberculosis_H37Rv         AGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFS-SATKESLIADLRTILA
MLBr_02348|M.leprae_Br4923          AGVPTLILWIFIEQPVWAAQIKRLKVGAGRRFS-ATTQRSLAADLRTILA
MMAR_0148|M.marinum_M               AGIPMLIRWLWLDQPIWAAGIEELGVGVGQPFS-ATTSESLAAGLGSILA
MUL_4949|M.ulcerans_Agy99           AGIPMLIRWLWLDQPIWAAGIEELGVGVGQPFS-AATSESLAAGLGSILA
MSMEG_4740|M.smegmatis_MC2_155      AARPTLILWVGADQPVWAAAVKRLQAGTAERFS-KVTPDSLLAGLQTVLT
TH_1989|M.thermoresistible__bu      AGVPSLVTWSSADQPYWGNQVKRLKVGTSRRFS-HTTPDTLVADLRRILT
Mflv_2592|M.gilvum_PYR-GCK          EGVPLVVAGDTEDKPEVAARVEYFGVGVNLRTG-TPAPQDLRDAVNAVLS
Mvan_4035|M.vanbaalenii_PYR-1       AGVPLVVAGSTEDKPEVAARVAWSGAGINLDTG-TPSADAIRSAVALLRS
                                     . * :      ::*  .  :     .         :   :   :    :

MAV_3653|M.avium_104                ER-TRARAGAVAATIRTDGAARAARLLVARLAG------------
MAB_4686|M.abscessus_ATCC_1997      DPGIKIRARRISDLLAAEDGAAHVVSSVNRLLG------------
Mb1551|M.bovis_AF2122/97            PD-YVTRAREIASRMTKPAASVTATADLLEDAARRAR--------
Rv1524|M.tuberculosis_H37Rv         PD-YVTRAREIASRMTKPAASVTATADLLEDAARRAR--------
MLBr_02348|M.leprae_Br4923          PQ-YATRAREVANRMSKPDESVNAAADLLEDKASRNKSRTRYQDC
MMAR_0148|M.marinum_M               AQ-YIARARTVAAQMTPPAHSIAMAADLLEHTAHVDRRS------
MUL_4949|M.ulcerans_Agy99           AQ-YIARARTVADQMTPPAHSIAMAADLLEHTAHVDRRS------
MSMEG_4740|M.smegmatis_MC2_155      PR-AALRARQIADEMTTPADSVRMTADLLEAAAARPMPA------
TH_1989|M.thermoresistible__bu      PD-YAVRARAVAARMTDPADSVVRAADLFETAVECAPGVAHRE--
Mflv_2592|M.gilvum_PYR-GCK          DAGYRTRAGRLQAAYASRDSVTAIAALLDEVIPEQAAAR------
Mvan_4035|M.vanbaalenii_PYR-1       DDRYLRNARRLEAAFARQDGIAEIAALIDELIGVRRTAAT-----
                                          .*  :                : .