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M. smegmatis MC2 155 MSMEG_4740 (-)

annotation: glycosyltransferase family protein 28
coordinates: 4839918 - 4841162
length: 414

KFVVAIHGTRGDIEPSATVATELRRRGHEVRMAVPPNLVPFVERIGLSAESYGVDSQQQLDADTFRDFWK
IRNPVKAIREGREYMVGGWAEMSATVAALADGADVLLTGTTYQEVVANVAESERIPLAALHYFPHRANSQ
ILPIRLPRRIVEPMWAVAEWGYWQILKSAEDAQRRELGLAPARSSSVNRIVSSGTLEIQAYDEVFFPGLR
QEWRGTRPFVGALTLELPTDTDDDVTAWAASGKPPIYFGFGSMPVQSPADAVTMISSVCTRLGERALISS
GAWNLDAIPESDHVKVVGAVNHAKIFPLCRAVVHHGGAGTTAAGLRAARPTLILWVGADQPVWAAAVKRL
QAGTAERFSKVTPDSLLAGLQTVLTPRAALRARQIADEMTTPADSVRMTADLLEAAAARPMPA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4740--100% (414)glycosyltransferase family protein 28
M. smegmatis MC2 155MSMEG_0392-e-11651.46% (412) glycosyl transferase
M. smegmatis MC2 155MSMEG_0385-e-11550.24% (410) glycosyl transferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1551-1e-13759.71% (412) glycosyltransferase
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv1524-1e-13759.71% (412) glycosyltransferase
M. leprae Br4923MLBr_02348-1e-12454.33% (416) putative glycosyl transferase
M. abscessus ATCC 19977MAB_4112c-1e-11751.67% (420) putative glycosyltransferase GtfA
M. marinum MMMAR_2353-1e-12251.70% (412) UDP-glycosyltransferase
M. avium 104MAV_3258-1e-12554.22% (415) glycosyltransferase family protein 28
M. thermoresistible (build 8)TH_1989-1e-4660.84% (143) Glycosyltransferase family protein 28
M. ulcerans Agy99MUL_4949-1e-10349.28% (414) glycosyltransferase
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_02348|M.leprae_Br4923          ---------------------MKFTLAASGSRGDVEPFAALGLELQRRGH
MMAR_2353|M.marinum_M               ---------------------MKFALAINGTRGDVEPCAALGRELSRRGH
Mb1551|M.bovis_AF2122/97            ---------------------MKFVVASYGTRGDIEPCAAVGLELQRRGH
Rv1524|M.tuberculosis_H37Rv         ---------------------MKFVVASYGTRGDIEPCAAVGLELQRRGH
MAV_3258|M.avium_104                ---------------------MRFALASYGTRGDIEPSAAVGRELLRRGH
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAB_4112c|M.abscessus_ATCC_199      MAENIDVHSVAHSDIGEVYTVMKFAMASYGTRGDIEPAVAVGRELQRRGH
MSMEG_4740|M.smegmatis_MC2_155      ---------------------MKFVVAIHGTRGDIEPSATVATELRRRGH
MUL_4949|M.ulcerans_Agy99           ---------------------MKAVVASYGSRGDVEPCAAAARELLRRGH
                                                                                      

MLBr_02348|M.leprae_Br4923          EVRIGVPPDMLRFVESAGLAAVAYG-PDTQEFLARDT---YSQWRQWWK-
MMAR_2353|M.marinum_M               EVRVAVPPNLTGLAAAAGLEAVPYG-PDTDELLNDE-----DNLQEFWK-
Mb1551|M.bovis_AF2122/97            DVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQLDEQ------FLHNAWK-
Rv1524|M.tuberculosis_H37Rv         DVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQLDEQ------FLHNAWK-
MAV_3258|M.avium_104                DVRLAVPPELVGFVESTGLAAVPYG-PNVQEFLDEE------FLRNMWRD
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAB_4112c|M.abscessus_ATCC_199      EVRMAVPPDLIGFAGSVGLSAVPYG-IHVGPQLDEYRDLWTSWTRHFWR-
MSMEG_4740|M.smegmatis_MC2_155      EVRMAVPPNLVPFVERIGLSAESYG-VDSQQQLDADT------FRDFWK-
MUL_4949|M.ulcerans_Agy99           EVRVAAPPNLVGFLESAGLTTVAYG-PDSHQQMGPAP-----NLVGDLAA
                                                                                      

MLBr_02348|M.leprae_Br4923          -ILPPIKALQQ----LRQAWADMATDLKSLADGADLVMTGVVYQGVVANV
MMAR_2353|M.marinum_M               -PQTSIKLVREGISDLRQAWSDMAGTLKTLADGADLVLTGMIHQGIALNA
Mb1551|M.bovis_AF2122/97            -LQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANV
Rv1524|M.tuberculosis_H37Rv         -LQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANV
MAV_3258|M.avium_104                FFRNPIRLVLKVWDPIIKYWAEASATLKSVAEGADLLSTGLNFEQAAANV
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAB_4112c|M.abscessus_ATCC_199      -LQDLVALCRQALKLVTEQWSEMSETLVSVAEGADLLSTSVGYEEPAANV
MSMEG_4740|M.smegmatis_MC2_155      -IRNPVKAIREGREYMVGGWAEMSATVAALADGADVLLTGTTYQEVVANV
MUL_4949|M.ulcerans_Agy99           TAQHPITMVPKLIEHLTRVNAAKSETLTALADGADLLVVGFNEQAVAANV
                                                                                      

MLBr_02348|M.leprae_Br4923          AEYYGIPFGVLHFVPARVNGKI-IPS-LPSPLNRAILATVWRAHWLLAKK
MMAR_2353|M.marinum_M               AEYYGIPLATMHFLPSRVNSRV-IPI-LSPRLNRSVISALWWVHWRVTKN
Mb1551|M.bovis_AF2122/97            AEHHGIPLAALHFYPVRANGEIAFPARLPAPLVRSTITAIDWLYWRMTKG
Rv1524|M.tuberculosis_H37Rv         AEHHGIPLAALHFYPVRANGEIAFPARLPAPLVRSTITAIDWLYWRMTKG
MAV_3258|M.avium_104                AEYYDIPLASLHHFPMRANGQL-VPN-MPSPLVRSTMTAIEWLFWRSTKK
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAB_4112c|M.abscessus_ATCC_199      AEFYGIPLVALHTMPWRPNGQL-FPV-LPPMLTRTGMTAYDWLTWRVTKG
MSMEG_4740|M.smegmatis_MC2_155      AESERIPLAALHYFPHRANSQI-LPIRLPRRIVEPMWAVAEWGYWQILKS
MUL_4949|M.ulcerans_Agy99           AEYFGIPLAGLHFFPAPA---------LPAGMLST----------LATKA
                                                                                      

MLBr_02348|M.leprae_Br4923          PEDAQRRELGLPKATSLSTRRIVKRGALEIQAYDELCFPGLAAEWAEYGD
MMAR_2353|M.marinum_M               PEEAQRRELGMAKASSSSTSRILKGRSLEIQAYDELCFPGLAAEWAEWGD
Mb1551|M.bovis_AF2122/97            VEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEWG---G
Rv1524|M.tuberculosis_H37Rv         VEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEWG---G
MAV_3258|M.avium_104                VDNAQRRQLGLPKATRRSQRRIAERGWLEIQAYDEVCFPGLAAEWAHWGD
TH_1989|M.thermoresistible__bu      --------------------------------------------------
MAB_4112c|M.abscessus_ATCC_199      AEDAQRRHLGLPQATSPSPQRIGQRNSLEIQAYDAVCFRGLAEEWAKYGG
MSMEG_4740|M.smegmatis_MC2_155      AEDAQRRELGLAPARSSSVNRIVSSGTLEIQAYDEVFFPGLRQEWR---G
MUL_4949|M.ulcerans_Agy99           ADDAQRQALGLPPASESVPQRVAEQGSLEIQAYDQIVLPGPPGRWVQADG
                                                                                      

MLBr_02348|M.leprae_Br4923          RRPFVGALTLELPTAADNEVLSWIAAGTPPIYFGFGSMPIVSPTDTVAMI
MMAR_2353|M.marinum_M               RRPFVGALTLEMPTESDNEVLSWIASGTPPIYFGFGSMPVESPAATIAMI
Mb1551|M.bovis_AF2122/97            RRPFVGALTMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAMI
Rv1524|M.tuberculosis_H37Rv         RRPFVGALTMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAMI
MAV_3258|M.avium_104                RRPFVGALTMELPTESDDDVASWIAAGTPPICFGSGSIPLESPTATVEMI
TH_1989|M.thermoresistible__bu      ------------------------------------------------MF
MAB_4112c|M.abscessus_ATCC_199      RRPFVGALTMELTTSADDEVMSWIASGPPPICFASGSIPVESPAETVEMI
MSMEG_4740|M.smegmatis_MC2_155      TRPFVGALTLELPTDTDDDVTAWAASGKPPIYFGFGSMPVQSPADAVTMI
MUL_4949|M.ulcerans_Agy99           RHPFIGALTLQSPTDDDDAILAWIAEGAPPIYFGFGSTPLTSPAEQFAMI
                                                                                    *:

MLBr_02348|M.leprae_Br4923          AAACADLGERALISVKPKDLTQVPKFDHVKIVTSVSHAAVFPACRAVVHH
MMAR_2353|M.marinum_M               SAACAELGERALICTGSNDLGGLQAPENVKLVSGVSHAAVFPACRAVVHH
Mb1551|M.bovis_AF2122/97            SAACAELGERALICSGPSDATGIPQFDHVKVVRVVSHAAVFPTCRAVVHH
Rv1524|M.tuberculosis_H37Rv         SAACAELGERALICSGPSDATGIPQFDHVKVVRVVSHAAVFPTCRAVVHH
MAV_3258|M.avium_104                GAASARLGERALICFGGTDVRGVPRFDHVKVVGPVNYASVFPACRAVVHH
TH_1989|M.thermoresistible__bu      ASVCSRLGERALICAGGTDIDGVPEYGHVKVVGAVNYARVFPACRAIVHH
MAB_4112c|M.abscessus_ATCC_199      GSACAELGERALVCAGATDFSGVQTSPHVKLVGVVNYAAVFPVSRAIVHH
MSMEG_4740|M.smegmatis_MC2_155      SSVCTRLGERALISSGAWNLDAIPESDHVKVVGAVNHAKIFPLCRAVVHH
MUL_4949|M.ulcerans_Agy99           SAACAQLGERALICAGPNDFGQMPHSHQVMVAPAVNHAAVFPACRAIVHH
                                    .:..: ******:.    :   :    :* :.  *.:* :** .**:***

MLBr_02348|M.leprae_Br4923          GGAGTTAASLRAGVPTLILWIFIEQPVWAAQIKRLKVGAGRRFSATTQRS
MMAR_2353|M.marinum_M               GGAGTTAAGMRAGIPTLILWIWIEQPIWLAQIKRLKIGSGRRLASTTKET
Mb1551|M.bovis_AF2122/97            GGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFSSATKES
Rv1524|M.tuberculosis_H37Rv         GGAGTTAAGLRAGIPTLILWVTSDQPIWAAQIKQLKVGRGRRFSSATKES
MAV_3258|M.avium_104                GGSGTTAASLRAGIPTLALWSSADQPYWAAQIKRLKVGTARRFSATTSET
TH_1989|M.thermoresistible__bu      GGSGTTAAVLRAGVPSLVTWSSADQPYWGNQVKRLKVGTSRRFSHTTPDT
MAB_4112c|M.abscessus_ATCC_199      GGSGTTAASLRAGVPTLILWTVGDQPFWGNQLRRMGVGASRRFSTTTRDS
MSMEG_4740|M.smegmatis_MC2_155      GGAGTTAAGLRAARPTLILWVGADQPVWAAAVKRLQAGTAERFSKVTPDS
MUL_4949|M.ulcerans_Agy99           GGAGTTAAGLRAGIPMLIRWLWLDQPIWAAGIEELGVGVGQPFSAATSES
                                    **:***** :**. * *  *   :** *   :..:  * .. :: .*  :

MLBr_02348|M.leprae_Br4923          LAADLRTILAPQYATRAREVANRMSKPDESVNAAADLLEDKASRNKSRTR
MMAR_2353|M.marinum_M               LVSDLRCILGPDYVARARTIANEMSKPGESATRAADLLENEVSVS-----
Mb1551|M.bovis_AF2122/97            LIADLRTILAPDYVTRAREIASRMTKPAASVTATADLLEDAARRAR----
Rv1524|M.tuberculosis_H37Rv         LIADLRTILAPDYVTRAREIASRMTKPAASVTATADLLEDAARRAR----
MAV_3258|M.avium_104                LAADLRTILAPDYATRARDLAARMTKPAESIETTADLLEEAARRKT-LG-
TH_1989|M.thermoresistible__bu      LVADLRRILTPDYAVRARAVAARMTDPADSVVRAADLFETAVECAPGVAH
MAB_4112c|M.abscessus_ATCC_199      LVSDLRTILTPECAARARAIAPHMSKPHDSVSKAADLLEAKASHP-----
MSMEG_4740|M.smegmatis_MC2_155      LLAGLQTVLTPRAALRARQIADEMTTPADSVRMTADLLEAAAARPMPA--
MUL_4949|M.ulcerans_Agy99           LAAGLGSILAAQYIARARTVADQMTPPAHSIAMAADLLEHTAHVDRRS--
                                    * :.*  :* .    *** :* .*: *  *   :***:*  .        

MLBr_02348|M.leprae_Br4923          YQDC
MMAR_2353|M.marinum_M               ----
Mb1551|M.bovis_AF2122/97            ----
Rv1524|M.tuberculosis_H37Rv         ----
MAV_3258|M.avium_104                ----
TH_1989|M.thermoresistible__bu      RE--
MAB_4112c|M.abscessus_ATCC_199      ----
MSMEG_4740|M.smegmatis_MC2_155      ----
MUL_4949|M.ulcerans_Agy99           ----