For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MHVDAMTVPQPLGQIGDLARRTQSAGFSGLLFTETGRTAYLNAAVASQAAPGLELSTGVAVAFPRSPFVT AAVAWELQEATKGRFRLGLGTQVRTHVVRRYGAAFERPGPRLRDYLLAVKACFAAFRSGTLEHHGDFYDL DFITPQWSPGPIDAPDPKVDIAAVNPWMLRMAGEVADGVHVHPIGEPGYLARHVLPTVAEGAAKAGRSPS DIAIIVPVMTIVGDSDEERDQQREAVRASMAFYGSTPNYAFIWDEAGFEGTTARIREKQKAGDYAGMAAQ VSDDHIAVFATESTWDGLADALIEKYSGTATRLVMYNSAADPERFERYGEVARRIQHAVSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2121 | - | - | 100% (341) | hypothetical protein MAV_2121 |
| M. avium 104 | MAV_4719 | - | 2e-44 | 33.44% (299) | hypothetical protein MAV_4719 |
| M. avium 104 | MAV_2543 | - | 1e-22 | 29.85% (268) | 5,10-methylenetetrahydromethanopterin reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3214 | - | 7e-51 | 66.67% (150) | hypothetical protein Mb3214 |
| M. gilvum PYR-GCK | Mflv_5162 | - | 1e-166 | 81.66% (338) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3192 | - | 7e-51 | 66.67% (150) | hypothetical protein Rv3192 |
| M. leprae Br4923 | MLBr_00348 | - | 3e-11 | 27.74% (292) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3914c | - | 2e-50 | 34.06% (323) | oxidoreductase |
| M. marinum M | MMAR_1372 | - | 1e-171 | 84.78% (335) | hypothetical protein MMAR_1372 |
| M. smegmatis MC2 155 | MSMEG_0341 | - | 5e-51 | 35.91% (298) | hypothetical protein MSMEG_0341 |
| M. thermoresistible (build 8) | TH_0425 | - | 1e-161 | 79.70% (335) | CONSERVED HYPOTHETICAL ALANINE AND PROLINE-RICH PROTEIN |
| M. ulcerans Agy99 | MUL_2504 | - | 1e-170 | 84.78% (335) | hypothetical protein MUL_2504 |
| M. vanbaalenii PYR-1 | Mvan_1168 | - | 1e-167 | 82.44% (336) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3214|M.bovis_AF2122/97 ----------------MIPQPLSQLGDLARR---PGRRVLCSPKTA-APS
Rv3192|M.tuberculosis_H37Rv ----------------MIPQPLSQLGDLARR---PGRRVLCSPKTA-APS
MMAR_1372|M.marinum_M ----------MHIDVMTIPQPLAQIGDLARRTQAAGFSGLLFTETG-RTA
MUL_2504|M.ulcerans_Agy99 ----------MHIDVMTIPQPLAQIGDLARRTQAAGLSGLLFTETG-RTA
MAV_2121|M.avium_104 ----------MHVDAMTVPQPLGQIGDLARRTQSAGFSGLLFTETG-RTA
Mflv_5162|M.gilvum_PYR-GCK ----------MHVDVMTTPQPLRSTGDLARRTQGAGFDGMLFTETG-RTA
Mvan_1168|M.vanbaalenii_PYR-1 ----------MHVDVMTTPQPLQSTGELARRTQEVGFSGLLFTETG-RTA
TH_0425|M.thermoresistible__bu ----------VHVDVMVVPQPLGRVGDTARQVQRCGFSGLLLTETG-RTA
MAB_3914c|M.abscessus_ATCC_199 -----------MLIDVTLTTGLNTMAAEAAEAEESGYAGIWTFEGA-HDP
MSMEG_0341|M.smegmatis_MC2_155 -------------MAGAEEAGISGLLGQAARAQDIGFDGIWSTDVD-RDP
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDA
. * : . .
Mb3214|M.bovis_AF2122/97 ISNATVASPAAPGLELSTGIALAFPRGPFVPAAAAWELQEATSGKFQLGL
Rv3192|M.tuberculosis_H37Rv ISNATVASPAAPGLELSTGIALAFPRGPFVPAAAAWELQEATSGKFQLGL
MMAR_1372|M.marinum_M YLNAAIASQAAPGLELSTGVAVAFPRSPFVTAATAWELQEATGGKFRLGL
MUL_2504|M.ulcerans_Agy99 YLNAAIASQAAPGLELSTGVAVAFPRSPFVTAATAWELQEATGGKFRLGL
MAV_2121|M.avium_104 YLNAAVASQAAPGLELSTGVAVAFPRSPFVTAAVAWELQEATKGRFRLGL
Mflv_5162|M.gilvum_PYR-GCK YLNVAAAALAAPGLQLSTGVAVAFPRSPFVTAASAWELQEASGGNFRLGL
Mvan_1168|M.vanbaalenii_PYR-1 YLSAAVAAHAAPGLELSTGVAVAFPRSPFVTAASAWELQEATGGKFRLGL
TH_0425|M.thermoresistible__bu YLNAAVASQAAPGLELSTGVAVAFPRSPFVTAAAAWELQEATGGKFRLGL
MAB_3914c|M.abscessus_ATCC_199 FLPLLLAAEHTKNVMLGTSIAVAFARNPMLLATIGWDLQAYSGGRFILGL
MSMEG_0341|M.smegmatis_MC2_155 FLPLAVAAMTTTNVQLGTGIAVAFARNPMTTAMAANDLQEMSDGRFVLGL
MLBr_00348|M.leprae_Br4923 YTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGL
. : : *.*.:. .* * * . *: : *.. ***
Mb3214|M.bovis_AF2122/97 GTQVRKNVVHRYGMAFHRPGPRLR-YLLAVKACFAVFQTG---TPDHHGE
Rv3192|M.tuberculosis_H37Rv GTQVRKNVVHRYGMAFHRPGPRLR-YLLAVKACFAVFQTG---TPDHHGE
MMAR_1372|M.marinum_M GTQVRTHVVRRYGMAFERPGPRLRDYVLAVKACFSAFRTG---TLDHHGE
MUL_2504|M.ulcerans_Agy99 GTQVRTHVVRRYGMAFERPGPRLRDYVLAVKACFSAFRTG---TLDHHGE
MAV_2121|M.avium_104 GTQVRTHVVRRYGAAFERPGPRLRDYLLAVKACFAAFRSG---TLEHHGD
Mflv_5162|M.gilvum_PYR-GCK GTQVRTHVVRRYGVEFEHPGPRLRDYVLAVKACFGAFRTG---TLDHHGD
Mvan_1168|M.vanbaalenii_PYR-1 GTQVRTHVVRRYGADFEHPGPRLRDYVLAVKACFAAFRTG---KLDHHGQ
TH_0425|M.thermoresistible__bu GTQVRTHVVRRYGMPFDRPGPRLRDYVRAVKACFTAFRTG---TLDHHGE
MAB_3914c|M.abscessus_ATCC_199 GTQIKPHITRRFDMPWSSPAARMRDMVLAVRAIWQSWQERG--ALDYRGD
MSMEG_0341|M.smegmatis_MC2_155 GTQIQAHIERRFSMPWSAPAERMSEYVNAIRAIWRSWRTGE--RLDFRGD
MLBr_00348|M.leprae_Br4923 GVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLP
*.. : :. : * * : :: : ..
Mb3214|M.bovis_AF2122/97 FDNPDFITAQWSPAR---IDPPGP------------------------SP
Rv3192|M.tuberculosis_H37Rv FDNPDFITAQWSPAR---IDPPGP------------------------SP
MMAR_1372|M.marinum_M FYDLDFITPQWSAGP---IDAPDPKVDVAAVNPWMLRMAGEVADGVHIHP
MUL_2504|M.ulcerans_Agy99 FYDLDLITPQWSAGP---IDAPDPKVDIAAVNPWMLRMAGEVADGVHIHP
MAV_2121|M.avium_104 FYDLDFITPQWSPGP---IDAPDPKVDIAAVNPWMLRMAGEVADGVHVHP
Mflv_5162|M.gilvum_PYR-GCK FYNLDFITPQWSAGP---IDAPDPKVDVAAVNPWMLRMAGEVADGVHVHP
Mvan_1168|M.vanbaalenii_PYR-1 FYNLDFITPQWSAGP---IDAPDPKVDVAAVNPWMLRMAGEVADGVHVHP
TH_0425|M.thermoresistible__bu FYELDFITPQWSPGP---IYAPDPKVDVAAVNPWMLRMAGEVADGVHVHP
MAB_3914c|M.abscessus_ATCC_199 FYQNTLMTPMFMPDPAEVSAFGPPPIWLAGVGTGMTEVAGEVADGFMSHP
MSMEG_0341|M.smegmatis_MC2_155 HYQHTLMTPMFTPTP---HPHGDPKIVISAVGPRMTRVAARDADGLLVHG
MLBr_00348|M.leprae_Br4923 LTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIF
Mb3214|M.bovis_AF2122/97 AG----------PR------------------------------------
Rv3192|M.tuberculosis_H37Rv AG----------PR------------------------------------
MMAR_1372|M.marinum_M LGELGYLTRHVVPNVAKGAAKAGRSPADIAVIVPVMTIVGDSEEERAIER
MUL_2504|M.ulcerans_Agy99 LGELGYLTRHVVPNVAKGAAKAGRSPADIAVILPVMTIVGDSDEERAIER
MAV_2121|M.avium_104 IGEPGYLARHVLPTVAEGAAKAGRSPSDIAIIVPVMTIVGDSDEERDQQR
Mflv_5162|M.gilvum_PYR-GCK LGEPGYIARHVIPKVAEGAQKSGRSPSEIALIVPVMTVVGDTDEERHRER
Mvan_1168|M.vanbaalenii_PYR-1 LGEPGYIARHVIPKIAEGAQNSGRSPDDIAVIVPVMTIVGDTDEERHRER
TH_0425|M.thermoresistible__bu IGEPGYLTRHVLPNVAAGAARSQRSPDDIALIVPVLTVVGDTDEERHTER
MAB_3914c|M.abscessus_ATCC_199 FCTPDYLAQVTRPALGRGALKSGKALADIQIHHSPMIIIGRDDAELASAR
MSMEG_0341|M.smegmatis_MC2_155 FTTQRYLSEVTLPIVEEELRKVGRRRADFTISYPGLIASGSTDEELTRAV
MLBr_00348|M.leprae_Br4923 FSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVT---EDRAAAF
Mb3214|M.bovis_AF2122/97 --------------------------------------------------
Rv3192|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1372|M.marinum_M ESVRASMAFYG------STPNYAFIWDEAGFEGTTARIREKQKAGDFPAM
MUL_2504|M.ulcerans_Agy99 ESVRASMAFYG------STPNYAFIWDEAGFEGTTARIREKQKAGDFPAM
MAV_2121|M.avium_104 EAVRASMAFYG------STPNYAFIWDEAGFEGTTARIREKQKAGDYAGM
Mflv_5162|M.gilvum_PYR-GCK ELVRASMSFYG------STPNYAFIWDEAGFEGTTARIREKQKAGDIKGM
Mvan_1168|M.vanbaalenii_PYR-1 ELVRASMSFYG------STPNYSFIWDEAGFEGTTARIRERQKAGDVKGM
TH_0425|M.thermoresistible__bu ERARAALSFYG------STPNYAFIWDEAGFEGTTARIREKQKARDHAGM
MAB_3914c|M.abscessus_ATCC_199 AAVRKQLAFYG------STPAYWPILELHGRAEMGPELKERSKQGEWEAM
MSMEG_0341|M.smegmatis_MC2_155 SAVRRQIAFYG------STPAYRHVLELHGWHDLHTELHRLSKAGDWTTM
MLBr_00348|M.leprae_Br4923 AGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKA
Mb3214|M.bovis_AF2122/97 --------------------------------------------------
Rv3192|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1372|M.marinum_M MAQISDEHVDAFATESSWDG-LADALTDKYGGIATRLVMYNALGDPGRFE
MUL_2504|M.ulcerans_Agy99 MAQISDEHIDAFATESSWDG-LADALTDKYGGIATRLVMYNALGDPGRFE
MAV_2121|M.avium_104 AAQVSDDHIAVFATESTWDG-LADALIEKYSGTATRLVMYNSAADPERFE
Mflv_5162|M.gilvum_PYR-GCK AAQITDEHIATFATESTWDG-LADALKAKYGGTATRIVLYNALANPERFE
Mvan_1168|M.vanbaalenii_PYR-1 AAQITDEHIAAFATESTWDG-LADALTAKYGGTATRVVLYNALADPERFE
TH_0425|M.thermoresistible__bu AAVITDEHLAVFTTESTWDG-LADALRARYGGVATRLVLYNAQNTPEQLE
MAB_3914c|M.abscessus_ATCC_199 AALVDDDFVDTAAVTVTDPGQGARELQERYGDLVHRLGFNTPYRPDRALL
MSMEG_0341|M.smegmatis_MC2_155 TGLIDDEVLNTFAA-VGEPTEAGAEVVTRFAGLVDRFTLLTPYPLGDEAA
MLBr_00348|M.leprae_Br4923 AEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLA
Mb3214|M.bovis_AF2122/97 ---------------
Rv3192|M.tuberculosis_H37Rv ---------------
MMAR_1372|M.marinum_M RYGEVARRMHG----
MUL_2504|M.ulcerans_Agy99 RYGEVARRMHG----
MAV_2121|M.avium_104 RYGEVARRIQHAVSG
Mflv_5162|M.gilvum_PYR-GCK RYGIVAQRLSNAQQA
Mvan_1168|M.vanbaalenii_PYR-1 RYGDVAQRLQR----
TH_0425|M.thermoresistible__bu RYGAVARQLSAD---
MAB_3914c|M.abscessus_ATCC_199 PELLA---AFPTR--
MSMEG_0341|M.smegmatis_MC2_155 AAIVAGARAATARA-
MLBr_00348|M.leprae_Br4923 GLF------------