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QAPSRYWENIVGETDLDVTDITGTLPDGLVGTLYRNGSGRWTVGSTQVESIFDADGMVSAFVLDGSGVRF RNRFVRTRHYLRSTAAGRLVDRGFAYQRPGGPRANALRLPANTANTSVMVNRNQLLALWEGGPPHELDLD TLDTIGPCNLGGALRGPVRAYSAHYRYDPMTNTKVNFGFDPYVPRIDPGHALRGPRRLRRLRELAAEAVP RVRLRLYETGADGVTRYLRAVPLPGMGVVHDMALTTRYAVFVLSPLRINPWALTGRQSYWESIRFKPDAP SYFVLAPRDGGAVRVVETDPFYHWHFTNAYDDGDDVVVELPRFAPQTYAGMKNYTAHIRSDIAQVDDYGA IEDAVVLTRFRIAASGRVTREPLADFGCEFPQIDPRRGTMRHHVSYLTVQDPAKFPGQGIARVDHRTGEA QTYCPPGHVLVEPIFVPRPGGTAEDDGWLLTVGYDESRHRSRLMVVDAAHVADGPVAEAWLQFHVPMSYH GTFTTRVAQRTG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3153 | - | - | 100% (503) | retinal pigment epithelial membrane protein |
| M. avium 104 | MAV_0560 | - | 2e-29 | 27.53% (523) | carotenoid oxygenase |
| M. avium 104 | MAV_4505 | - | 2e-27 | 26.93% (531) | Sim14 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0937c | - | 1e-29 | 26.26% (495) | dioxygenase |
| M. gilvum PYR-GCK | Mflv_1807 | - | 4e-31 | 27.52% (487) | carotenoid oxygenase |
| M. tuberculosis H37Rv | Rv0913c | - | 2e-29 | 26.26% (495) | dioxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3874c | - | 4e-27 | 25.95% (551) | putative dioxygenase |
| M. marinum M | MMAR_4614 | - | 3e-30 | 26.02% (492) | dioxygenase |
| M. smegmatis MC2 155 | MSMEG_1564 | - | 1e-84 | 37.00% (500) | lignostilbene-alpha,beta-dioxygenase |
| M. thermoresistible (build 8) | TH_3525 | - | 9e-93 | 40.20% (500) | PUTATIVE lignostilbene-alpha,beta-dioxygenase |
| M. ulcerans Agy99 | MUL_0155 | - | 2e-29 | 25.81% (492) | dioxygenase |
| M. vanbaalenii PYR-1 | Mvan_3359 | - | 0.0 | 75.25% (501) | carotenoid oxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4614|M.marinum_M ----MDVEIVGKYLSTLPEDDDHPYRTGPWRPQTTEWNADDLTVVEGEIP
MUL_0155|M.ulcerans_Agy99 ----MDVEIVGKYLSTLPEDDDHPYRTGPWRPQTTEWNADDLTVVEGEIP
Mb0937c|M.bovis_AF2122/97 ----MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVP
Rv0913c|M.tuberculosis_H37Rv ----MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVP
Mflv_1807|M.gilvum_PYR-GCK MTAGTHPEVVGKFLSTLPEDDDHPYRTGPWRPQTTEWDDDDLRVVEGQIP
MAV_3153|M.avium_104 -----------------------MQAPSRYWENIVGETDLDVTDITGTLP
Mvan_3359|M.vanbaalenii_PYR-1 -----------------------MVAGTRYWDDIDGEFDIPVEEITGTLP
MSMEG_1564|M.smegmatis_MC2_155 ------MHRSPPRLAPSDVTEGTFSPYSPYNTSLYEEYDYTIDDVEGALP
TH_3525|M.thermoresistible__bu --------MSP---EPVGSRQQDFSGFTP----LHEEYDYLLDEVAGAVP
MAB_3874c|M.abscessus_ATCC_199 ------------MTATAQPAASTSPYLSGIWEPVQQEMDSVDLEVTGTLP
: * :*
MMAR_4614|M.marinum_M HDLDGVYLRNTENPLHP-AFKTYHPFDGDGMLHVVGFRDG-KAFYRNRFI
MUL_0155|M.ulcerans_Agy99 HDLDGVYLRNTENPLHP-AFKTYHPFDGDGMLHVVGFRDG-KAFYRNRFI
Mb0937c|M.bovis_AF2122/97 ADLDGIYLRNTENPLHP-AFATYHPFDGDGMIHVVGFRDG-KAFYRNRFI
Rv0913c|M.tuberculosis_H37Rv ADLDGIYLRNTENPLHP-AFATYHPFDGDGMIHVVGFRDG-KAFYRNRFI
Mflv_1807|M.gilvum_PYR-GCK GDLDGVYLRNTENPLHP-ALKYYHPFDGDGMLHMVGFRDG-KAFYRNRFV
MAV_3153|M.avium_104 DGLVGTLYRNGSGRWTVGSTQVESIFDADGMVSAFVLDGS-GVRFRNRFV
Mvan_3359|M.vanbaalenii_PYR-1 EGLTGTLYRNGSGRWNIGSSPVESIYDADGMVSAFVLNGA-GVRFRNRFV
MSMEG_1564|M.smegmatis_MC2_155 DGLRGTLYRNGPGKLDAGGQQLGHLFDGDGMLSMFVMSDG-TVRFRNRYV
TH_3525|M.thermoresistible__bu EQLRGTVYRNGPGRLEAGGQPLGHLFDGDGMLSMFRFADG-RVRFRNRYV
MAB_3874c|M.abscessus_ATCC_199 AHLDGRYLRNGPNPAAEVDPATYHLFSGDAMVHGLSLREGKAQWYRNRWV
* * ** . :..*.*: . : . :***::
MMAR_4614|M.marinum_M QTDGFQAENEAGEPLWPGLAEPIQLAKRDQGWGARTLMKDASSTDVIVHR
MUL_0155|M.ulcerans_Agy99 QTDGFRAENEAGEPLWPGLAEPIQLAKRDQGWGARTLMKDASSTDVIVYR
Mb0937c|M.bovis_AF2122/97 RTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASSTDVIVHR
Rv0913c|M.tuberculosis_H37Rv RTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASSTDVIVHR
Mflv_1807|M.gilvum_PYR-GCK RTDALAAENEAGGPLWPGIAEPIELAKRDYGWGARTLMKDASSTDVIVHR
MAV_3153|M.avium_104 RTRHYLRSTAAGRLVDRGFAYQRPGGPRAN---ALRLPANTANTSVMVNR
Mvan_3359|M.vanbaalenii_PYR-1 RTRHFVQSTRAGRPIGRGFSAQRPGGIRAN---ALRLPVNTANTSVMMNN
MSMEG_1564|M.smegmatis_MC2_155 RTKHYEKSLASKGAPYRALGTMRPGGILAN---ALRLPANVANTGVVMHA
TH_3525|M.thermoresistible__bu RTRHYRRSRHTRGAPFRGLGTMRPGGVLAN---ALRFPVNVANTAVIMHA
MAB_3874c|M.abscessus_ATCC_199 RTPSVSKT----------LGETRPAAISAN----AGMGVIGPNTNVLGHA
:* :. . : ..* *:
MMAR_4614|M.marinum_M GIALTSFYQCGDLYRVDPSSATTLGKENWSGNFP-FDWGVSAHPKVDGKT
MUL_0155|M.ulcerans_Agy99 GIALTSFYQCGDLYRVDPSSATTLGKETWSGHFP-FDWGVSAHPKVDGKT
Mb0937c|M.bovis_AF2122/97 GIALTSFYQCGDLYRIDPYSANTLGKESWHGRFP-FDWGVSAHPKVDNKT
Rv0913c|M.tuberculosis_H37Rv GIALTSFYQCGDLYRIDPYSANTLGKESWHGRFP-FDWGVSAHPKVDNKT
Mflv_1807|M.gilvum_PYR-GCK GVALTSHYQCGDLYRIDPCTGADLGKEDWNGGFP-TDWGVSAHPKVDDRT
MAV_3153|M.avium_104 -NQLLALWEGGPPHELDLDTLDTIGPCNLGGALRGPVRAYSAHYRYDPMT
Mvan_3359|M.vanbaalenii_PYR-1 -DRLLALWEGGRPHELDPDSLDTYGMSDLGGALRGPVGAYSAHYTLDPET
MSMEG_1564|M.smegmatis_MC2_155 -GKLLALWEGGRPTRIHPDTLDTLGAHDFDGGLK-WLGAFSAHPKWDFAT
TH_3525|M.thermoresistible__bu -GTLLALWEAGRPTEIDPDSLDTVGEYDYDGELR-WLGAFSAHPKWDPDT
MAB_3874c|M.abscessus_ATCC_199 -GRTLALVEGGIANYELTEDLDTIGTCDFDGTLP---GGYTAHPHTDPDT
: : * * * : . :** * *
MMAR_4614|M.marinum_M GELLFFNYS-------------------------------KQEPYMRYGV
MUL_0155|M.ulcerans_Agy99 GELLFFNYS-------------------------------KQEPYMRYGV
Mb0937c|M.bovis_AF2122/97 GELLFFNYS-------------------------------KQEPYMRYGV
Rv0913c|M.tuberculosis_H37Rv GELLFFNYS-------------------------------KQEPYMRYGV
Mflv_1807|M.gilvum_PYR-GCK GELLFFNYS-------------------------------KQAPFMRYGV
MAV_3153|M.avium_104 NTKVNFGFDPYVPRIDPGHALR---GPRRLRRLRELAAEAVPRVRLRLYE
Mvan_3359|M.vanbaalenii_PYR-1 GAKVNFGFDPYFPRIDLRWALRGVSGAERRRRLRDLVGEAVPRVRLRLYE
MSMEG_1564|M.smegmatis_MC2_155 GDMFNFGLA------------------------------MFPTPKLICYR
TH_3525|M.thermoresistible__bu GEMFNFGLA------------------------------LAPIPKLVCYR
MAB_3874c|M.abscessus_ATCC_199 GEMHAVSYS------------------------------FARGSTVQYSV
. .. :
MMAR_4614|M.marinum_M VDQDNELAHYVDIPLPGPRLPHDMAFTENYAILNDFPLFWDP--------
MUL_0155|M.ulcerans_Agy99 VDQDNELAHYVDIPLPGPRLPHDMAFTENYAILNDFPLFWDP--------
Mb0937c|M.bovis_AF2122/97 VDQNNELVHYVDVPLPGPRLLHDMAFTENYVILNDFPLFWDP--------
Rv0913c|M.tuberculosis_H37Rv VDQNNELVHYVDVPLPGPRLPHDMAFTENYVILNDFPLFWDP--------
Mflv_1807|M.gilvum_PYR-GCK VSPAGDVVHNVDVPLPGPRLPHDMAFTENYVILNDFPLFWDT--------
MAV_3153|M.avium_104 TGADGVTRYLRAVPLPGMGVVHDMALTTRYAVFVLSPLRINP--------
Mvan_3359|M.vanbaalenii_PYR-1 TDTDGVTRYLRAVPLPGMGIVHDMALTRRYAIFVVSPMRINP--------
MSMEG_1564|M.smegmatis_MC2_155 VDRTGRLHRLGHVPLPRPMFNHDVGLTHHHMVFVIPPLVFPLRRS-----
TH_3525|M.thermoresistible__bu VDPTGRLTTLGAVRLSAPMFNHDVGLTKRHMVFVVPPLVFRPSKL-----
MAB_3874c|M.abscessus_ATCC_199 IDAHGRARRTVDIPVHGAPMMHDFTLTEKYVVFYDLPVTLDMSMISQSVP
. . : : . **. :* .: :: *:
MMAR_4614|M.marinum_M --------------------------------QLLEHNLHLPRFYPDMPS
MUL_0155|M.ulcerans_Agy99 --------------------------------QLLEHNLHLPRFYPDMPS
Mb0937c|M.bovis_AF2122/97 --------------------------------RLLERDVHLPRFYPEIPS
Rv0913c|M.tuberculosis_H37Rv --------------------------------RLLERDVHLPRFYPEIPS
Mflv_1807|M.gilvum_PYR-GCK --------------------------------GLLEHNIHLPRFHRDVPS
MAV_3153|M.avium_104 -----------------------------WALTGRQSYWESIRFKPDAPS
Mvan_3359|M.vanbaalenii_PYR-1 -----------------------------WALTGHASFWDSMRFLTDTPT
MSMEG_1564|M.smegmatis_MC2_155 ----------------------------LEAGIGVRNFIDAIDFDATRGT
TH_3525|M.thermoresistible__bu ----------------------------AGAALGLHDYIDALEYDAERPT
MAB_3874c|M.abscessus_ATCC_199 VPRLLRKPAQIVMNSLIGKVKIPGPIAAKASQYSGKSPSIPYSWNPKYPA
: :
MMAR_4614|M.marinum_M RFAVIPRRGSTA----DIRWFEADPTFVLHFTNAYEEGDE----IVLDG-
MUL_0155|M.ulcerans_Agy99 RFAVIPRRGSTA----DIRWFEADPTFVLHFTNAYEEGDE----IVLDG-
Mb0937c|M.bovis_AF2122/97 RFAVVARRGN------DIRWFEADPTFVLHFTNAYEQGDE----IVLDG-
Rv0913c|M.tuberculosis_H37Rv RFAVVARRGN------DIRWFEADPTFVLHFTNAYEQGDE----IVLDG-
Mflv_1807|M.gilvum_PYR-GCK RFAVLPRRGDTS----QIMWFEADPTYVLHFPNAFEDGDE----IVLDG-
MAV_3153|M.avium_104 YFVLAPRDGG------AVRVVETDPFYHWHFTNAYDDGDD----VVVELP
Mvan_3359|M.vanbaalenii_PYR-1 YFLLAPRSGG------PVRTVETDAFYHWHFTNAYDDGDD----VVVELP
MSMEG_1564|M.smegmatis_MC2_155 MIALVPRDGG------RSRILHTDPSLHLHLSNAYEDGED----TVVELV
TH_3525|M.thermoresistible__bu MIALVPRDGG------RVRIVHTEPLMHLHIANAYDDGAD----TVVELL
MAB_3874c|M.abscessus_ATCC_199 RIGVMPREGDDASRHAPVRWFEIDPCYVFHPLNGYSEMRNGAEVIVIDLV
: : .* *. .. :. * *.:.: : *::
MMAR_4614|M.marinum_M FFEGAPHPLE--TSASSTKWEKLFRFLALDRLQTRLHRWRLNLVTGAVKE
MUL_0155|M.ulcerans_Agy99 FFEGAPHPLE--TSASSTKWEKLFRFLALDRLQTRLHRWRLNLVTGAVKE
Mb0937c|M.bovis_AF2122/97 FYEGDPQPLD--TGG--TKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHE
Rv0913c|M.tuberculosis_H37Rv FYEGDPQPLD--TGG--TKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHE
Mflv_1807|M.gilvum_PYR-GCK FFQGDPEPTQGVDNGMSRKWQQIFRSLSLDGMQTRLHRWRFNLKTGAVRE
MAV_3153|M.avium_104 RFAPQTYAGMKNYTAHIRSDIAQVDDYGAIEDAVVLTRFRIAAS-GRVTR
Mvan_3359|M.vanbaalenii_PYR-1 RFAPHTYEGVKNYTAHVRSGSAQVGG-ADPSDAVVLTRFRIGSS-GRVTR
MSMEG_1564|M.smegmatis_MC2_155 DYH----SSWQELNGQLSLVPTLAQT-ATMPYGGQLTRLRITPS-GHVSR
TH_3525|M.thermoresistible__bu NYD----ASWTQLNAQLLTVDGTVPD-TTMPYGGVLRRIRITRS-GRVIH
MAB_3874c|M.abscessus_ATCC_199 RYDS----------------MFSQDVLGPSDAKGQLDRWTIDLAKGTVHM
: * * : * *
MMAR_4614|M.marinum_M ERLSESITEFGTINSDYAARQYRYAYAATGK----PGWFLFDGLVKHDLL
MUL_0155|M.ulcerans_Agy99 ERLSESITEFGTINSDYAARQYRYAYAATGK----PGWFLFDGLVKHDLL
Mb0937c|M.bovis_AF2122/97 EQLSESITEFGTINADYAASSYRYTYAATGK----PSWFLFDGLVKHDLL
Rv0913c|M.tuberculosis_H37Rv EQLSESITEFGTINADYAASSYRYTYAATGK----PSWFLFDGLVKHDLL
Mflv_1807|M.gilvum_PYR-GCK EHLSDSFTEFGMINPGFSGRPHRYTYAETGK----PGWFLFDGLVKHDLH
MAV_3153|M.avium_104 EPLADFGCEFPQIDPRRGTMRHHVSYLTVQD----PAKFPGQGIARVDHR
Mvan_3359|M.vanbaalenii_PYR-1 EPLADFGCEFPQIDPRRSTRRHDYSYVAVQD----PVRFQGQGIARIDHR
MSMEG_1564|M.smegmatis_MC2_155 EPITDLYGEFPMLNVKTMASQNRYTYLSAAL----GGNIYPNAVAKIDNT
TH_3525|M.thermoresistible__bu EPLTDLRGDFPMLNPRVSGRRHRYTYLVVGV----EGSTYPNAVAKLDHH
MAB_3874c|M.abscessus_ATCC_199 ERKDDRHLEFPRINETFTGKKHRYGYLPDVENFFGSGEAAGASIVKYDYE
* : :* :: * .:.: *
MMAR_4614|M.marinum_M TGNQEGISFGEGVYGSETQMAPRVGSSAEDDGYLVTLTTDMNDDASYCLV
MUL_0155|M.ulcerans_Agy99 TGNQEGISFGEGVYGSETQMAPRVGSSAEDDGYLVTLTTDMNDDASYCLV
Mb0937c|M.bovis_AF2122/97 TGNHECYSFGDGVYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLV
Rv0913c|M.tuberculosis_H37Rv TGNHECYSFGDGVYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLV
Mflv_1807|M.gilvum_PYR-GCK TGTEQRFTFDDGVFGSETAMAPRVGGTDEDDGYLVTLTTDMNTDASYCLV
MAV_3153|M.avium_104 TGEAQTY-CPPGHVLVEPIFVPRPGGTAEDDGWLLTVGYDESRHRSRLMV
Mvan_3359|M.vanbaalenii_PYR-1 SGAGQVF-CPPGNVLVEPTFVPRPGGDAEDDGWVITVGYQESHHRSRLMV
MSMEG_1564|M.smegmatis_MC2_155 TGKETVYRLPDGHLPHEAIFAAHPDGVDEDDGWLLVPVIDGVENIASLII
TH_3525|M.thermoresistible__bu TGASTLHRLPPGHLAHEPVFIPRPGGAAEDDGWLAVVVQDCHRHRAHLRL
MAB_3874c|M.abscessus_ATCC_199 TGSTLSSRLDPAIVLGEMSFVPNPTCAAEDDGVLIGFAVDRRSDEGQLLL
:* . * : .. **** : : . . :
MMAR_4614|M.marinum_M FDAARIADGPVCKLELPERISSGTHSTWVPGNELRRWHHADSAPSAIGL
MUL_0155|M.ulcerans_Agy99 FDAARIADGPVCKLELPERISSGTHSTWVPGNELRRWHHADSAPSAIGL
Mb0937c|M.bovis_AF2122/97 FDAARPGDGPICKLALPERISSGTHSAWVPGAELRRWDHAESPAAAVGL
Rv0913c|M.tuberculosis_H37Rv FDAARPGDGPICKLALPERISSGTHSAWVPGAELRRWDHAESPAAAVGL
Mflv_1807|M.gilvum_PYR-GCK FDAARVGDGPVCKLQLPERISSGTHSTWAAGCDLPRWRDSESAAGAIGL
MAV_3153|M.avium_104 VDAAHVADGPVAEAWLQFHVPMSYHGTFTTRVAQRTG------------
Mvan_3359|M.vanbaalenii_PYR-1 FDAAGIADGPVAEAWLPFHVPMSYHGTFTSRVAR---------------
MSMEG_1564|M.smegmatis_MC2_155 LDAKDIEAGPVYQGRLRHHLPLTFHGCYTPRVAAPA-------------
TH_3525|M.thermoresistible__bu LDAGAVSADPVFTGHLRHSMPLTFHGCFTPRVGRSG-------------
MAB_3874c|M.abscessus_ATCC_199 LDATSLD--LMATVHLPQRVPAGFHGNWAPR------------------
.** : * :. *. :..