For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3525 | - | - | 100% (483) | lignostilbene-alpha,beta-dioxygenase |
| M. thermoresistible (build 8) | TH_3959 | - | 7e-45 | 31.20% (500) | PUTATIVE Carotenoid oxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0673 | - | 1e-37 | 29.98% (497) | dioxygenase |
| M. gilvum PYR-GCK | Mflv_2111 | - | 2e-47 | 32.67% (499) | carotenoid oxygenase |
| M. tuberculosis H37Rv | Rv0654 | - | 1e-37 | 29.98% (497) | dioxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3874c | - | 5e-44 | 30.29% (525) | putative dioxygenase |
| M. marinum M | MMAR_0993 | - | 1e-35 | 29.39% (490) | dioxygenase |
| M. avium 104 | MAV_3153 | - | 1e-92 | 40.20% (500) | retinal pigment epithelial membrane protein |
| M. smegmatis MC2 155 | MSMEG_1564 | - | 1e-180 | 64.07% (462) | lignostilbene-alpha,beta-dioxygenase |
| M. ulcerans Agy99 | MUL_0744 | - | 4e-36 | 28.97% (497) | dioxygenase |
| M. vanbaalenii PYR-1 | Mvan_0203 | - | 1e-96 | 43.84% (463) | carotenoid oxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0673|M.bovis_AF2122/97 -------MTTAQAAESQNPYLEGFLAPVSTEVTATDLPVTGRIPEHLDGR
Rv0654|M.tuberculosis_H37Rv -------MTTAQAAESQNPYLEGFLAPVSTEVTATDLPVTGRIPEHLDGR
MMAR_0993|M.marinum_M -------MTTMRSAQPRNPYLEGFLAPVRAEVTATDLEVTGRIPDYLDGR
MUL_0744|M.ulcerans_Agy99 -------MTTMRSAQPRNPYLEGFLAPVRAEVTATDLEVTGRIPDYLDGR
MAB_3874c|M.abscessus_ATCC_199 ------MTATAQPAASTSPYLSGIWEPVQQEMDSVDLEVTGTLPAHLDGR
Mflv_2111|M.gilvum_PYR-GCK ---------------MANRYLEGAFAPISEEHTLTDLDVIGTIPDHLDGR
TH_3525|M.thermoresistible__bu --MSP---EPVGSRQQDFSGFTP----LHEEYDYLLDEVAGAVPEQLRGT
MSMEG_1564|M.smegmatis_MC2_155 MHRSPPRLAPSDVTEGTFSPYSPYNTSLYEEYDYTIDDVEGALPDGLRGT
MAV_3153|M.avium_104 ------MQAPSRYWEN-----------IVGETDLDVTDITGTLPDGLVGT
Mvan_0203|M.vanbaalenii_PYR-1 --MGPDDLSSLGVSEP-----------QPAEHDYRVEQIDGTIPAGLRGT
* : * :* * *
Mb0673|M.bovis_AF2122/97 YLRNGPN-PVAEVDPATYHWFTGDAMVHGVALRDGKARWYRNRWVRT---
Rv0654|M.tuberculosis_H37Rv YLRNGPN-PVAEVDPATYHWFTGDAMVHGVALRDGKARWYRNRWVRT---
MMAR_0993|M.marinum_M YLRNGPN-PVAEVNPATYHWFTGDGMVHGVALRDGRASWYRNRWVRS---
MUL_0744|M.ulcerans_Agy99 YLRNGPN-PVAEVNPATYHWFTGDGMVHGVALRDGRASWYRNRWVRS---
MAB_3874c|M.abscessus_ATCC_199 YLRNGPN-PAAEVDPATYHLFSGDAMVHGLSLREGKAQWYRNRWVRT---
Mflv_2111|M.gilvum_PYR-GCK YLRNGPN-PIGDLDPALYHWFIGDGMVHGIRIRDGRAEWYRNRWVRG---
TH_3525|M.thermoresistible__bu VYRNGPGRLEAG-GQPLGHLFDGDGMLSMFRFADG-RVRFRNRYVRTRHY
MSMEG_1564|M.smegmatis_MC2_155 LYRNGPGKLDAG-GQQLGHLFDGDGMLSMFVMSDG-TVRFRNRYVRTKHY
MAV_3153|M.avium_104 LYRNGSGRWTVG-STQVESIFDADGMVSAFVLDGS-GVRFRNRFVRTRHY
Mvan_0203|M.vanbaalenii_PYR-1 LYRNGPGRWEDHKGRPLRHLFDGDGMLSAFTIDAA-GVHYRNRYVRTRHF
***.. . * .*.*: . : . :***:**
Mb0673|M.bovis_AF2122/97 -------PAVCAALGEPISARPHPRTG-IIEGGPNTNVLTHAGRTLALVE
Rv0654|M.tuberculosis_H37Rv -------PAVCAALGEPISARPHPRTG-IIEGGPNTNVLTHAGRTLALVE
MMAR_0993|M.marinum_M -------MPVCAALGESPPSRLDPRAG-MLGLGANTNVLSHAGRTLALVE
MUL_0744|M.ulcerans_Agy99 -------MPVCAALGESPPARRDPRAG-MLGLGANTNVLSHAGRTLALVE
MAB_3874c|M.abscessus_ATCC_199 -------PSVSKTLGETRPAAISANAG-MGVIGPNTNVLGHAGRTLALVE
Mflv_2111|M.gilvum_PYR-GCK -------PAAARALGESVP---DGRFP-ISGIGANTNVIGHAGKTLALIE
TH_3525|M.thermoresistible__bu RRSRHTRGAPFRGLGTMRPGGVLANALRFPVNVANTAVIMHAGTLLALWE
MSMEG_1564|M.smegmatis_MC2_155 EKSLASKGAPYRALGTMRPGGILANALRLPANVANTGVVMHAGKLLALWE
MAV_3153|M.avium_104 LRSTAAGRLVDRGFAYQRPGGPRANALRLPANTANTSVMVNRNQLLALWE
Mvan_0203|M.vanbaalenii_PYR-1 G-----GRGGVSHMGTSAPGGWRANICRVPPNLANTNVVEHAGRLYALWE
:. . . . .** *: : . ** *
Mb0673|M.bovis_AF2122/97 AGVVNYELTDELDTVGPCDFDGTLH---GGYTAHPQRDPHTGELHAVS--
Rv0654|M.tuberculosis_H37Rv AGVVNYELTDELDTVGPCDFDGTLH---GGYTAHPQRDPHTGELHAVS--
MMAR_0993|M.marinum_M GGVANYELTDDLDTVGTCDFDGTLP---GGYTAHPHRDPQTGELHAVS--
MUL_0744|M.ulcerans_Agy99 GGVANYELTDDLDTVGTCDFDGTLP---GGYTAHPHRDPQTGELHAVS--
MAB_3874c|M.abscessus_ATCC_199 GGIANYELTEDLDTIGTCDFDGTLP---GGYTAHPHTDPDTGEMHAVS--
Mflv_2111|M.gilvum_PYR-GCK AGVPNYELTDDLDTVGTCDFDGTLS---GGYTAHPKRDPDTGELHAVS--
TH_3525|M.thermoresistible__bu AGRPTEIDPDSLDTVGEYDYDGELR-WLGAFSAHPKWDPDTGEMFNFG--
MSMEG_1564|M.smegmatis_MC2_155 GGRPTRIHPDTLDTLGAHDFDGGLK-WLGAFSAHPKWDFATGDMFNFG--
MAV_3153|M.avium_104 GGPPHELDLDTLDTIGPCNLGGALRGPVRAYSAHYRYDPMTNTKVNFGFD
Mvan_0203|M.vanbaalenii_PYR-1 GGPPHEIDPDTLETMGVRRFGGELR-WLGSYSAHPSFCPSSGAMFNFG--
.* : *:*:* .* * .::** :. ..
Mb0673|M.bovis_AF2122/97 -------------------------YSFARGHRVQYSVIGTDGHARRTVD
Rv0654|M.tuberculosis_H37Rv -------------------------YSFARGHRVQYSVIGTDGHARRTVD
MMAR_0993|M.marinum_M -------------------------YSFTRGHTVQYSVIDTQGRARRTVD
MUL_0744|M.ulcerans_Agy99 -------------------------YSFTRGHMVQYSVIDTQGRARRTVD
MAB_3874c|M.abscessus_ATCC_199 -------------------------YSFARGSTVQYSVIDAHGRARRTVD
Mflv_2111|M.gilvum_PYR-GCK -------------------------YSMLRGNTVQYSVIDTGGRARRTVD
TH_3525|M.thermoresistible__bu -------------------------LALAPIPKLVCYRVDPTGRLTTLGA
MSMEG_1564|M.smegmatis_MC2_155 -------------------------LAMFPTPKLICYRVDRTGRLHRLGH
MAV_3153|M.avium_104 PYVPRIDPGHALRGPRRLRRLRELAAEAVPRVRLRLYETGADGVTRYLRA
Mvan_0203|M.vanbaalenii_PYR-1 -------------------------VELMPRPHLRIYRTDRTGRLRHFRS
: . *
Mb0673|M.bovis_AF2122/97 IEVAGSPMMHSFSLTDNYVVIYDLPVTFDPMQVVP-ASVPRWLQRPARLV
Rv0654|M.tuberculosis_H37Rv IEVAGSPMMHSFSLTDNYVVIYDLPVTFDPMQVVP-ASVPRWLQRPARLV
MMAR_0993|M.marinum_M IEVTGSPMMHDFSLTDKYVVIYDLPVTFDSAQVMP-VKMPSWLGVPARLV
MUL_0744|M.ulcerans_Agy99 IEVTGSPMMHDFSLTDKYVVIYDLPVTFDSAQVMP-VKMPSWLGVPARLV
MAB_3874c|M.abscessus_ATCC_199 IPVHGAPMMHDFTLTEKYVVFYDLPVTLDMSMISQSVPVPRLLRKPAQIV
Mflv_2111|M.gilvum_PYR-GCK IEVAGSPMMHDFSLTERHVIFYDLPVTFDTRRAVE-MTVPRGLRLPARLV
TH_3525|M.thermoresistible__bu VRLSAPMFNHDVGLTKRHMVFVVPPLVFRP-----------------SKL
MSMEG_1564|M.smegmatis_MC2_155 VPLPRPMFNHDVGLTHHHMVFVIPPLVFPL-----------------RRS
MAV_3153|M.avium_104 VPLPGMGVVHDMALTTRYAVFVLSPLRIN--------------------P
Mvan_0203|M.vanbaalenii_PYR-1 AALPYAAMVHDFAITERYIVFLISPIIPD--------------------A
: . *.. :* .: :: *:
Mb0673|M.bovis_AF2122/97 IQSVLGRVRIPDPIAALGNRMQGHSDRLPYAWNPSYPARVGVMPREGGNE
Rv0654|M.tuberculosis_H37Rv IQSVLGRVRIPDPIAALGNRMQGHSDRLPYAWNPSYPARVGVMPREGGNE
MMAR_0993|M.marinum_M MASLIGNVRVPSPIAAMMNRNPKPSNRLPYAWNPAYPARIGVMPREGGNR
MUL_0744|M.ulcerans_Agy99 MASLIGNVRVPSLIAAMLNRNPKPSNRLPYAWNPAYPARIGVMPREGGNR
MAB_3874c|M.abscessus_ATCC_199 MNSLIGKVKIPGPIAAKASQYSGKSPSIPYSWNPKYPARIGVMPREGDDA
Mflv_2111|M.gilvum_PYR-GCK LSALIGRVRIPDPVAARQPSGSGSDRRFPYSWNPRYPARIGVMPRDGGSA
TH_3525|M.thermoresistible__bu AGAALGLHDYIDALEYDAER----------------PTMIALVPRDGGRV
MSMEG_1564|M.smegmatis_MC2_155 LEAGIGVRNFIDAIDFDATR----------------GTMIALVPRDGGRS
MAV_3153|M.avium_104 WALT-GRQSYWESIRFKPDA----------------PSYFVLAPRDGGAV
Mvan_0203|M.vanbaalenii_PYR-1 MSVALGRAPIGDTLRYRPER----------------GSVVLLVPRAGGKI
* : : . : ** *.
Mb0673|M.bovis_AF2122/97 D----VRWFDIEPCYVYHPLNAYSECRNGAEVLVLDVVR-----------
Rv0654|M.tuberculosis_H37Rv D----VRWFDIEPCYVYHPLNAYSECRNGAEVLVLDVVR-----------
MMAR_0993|M.marinum_M D----VRWFDIEPCYVYHPLNAYSEHRDGAEVLILDVVR-----------
MUL_0744|M.ulcerans_Agy99 D----VRWFDIEPCYVYHPLNAYSEHRDGAEVLILDVVR-----------
MAB_3874c|M.abscessus_ATCC_199 SRHAPVRWFEIDPCYVFHPLNGYSEMRNGAEVIVIDLVR-----------
Mflv_2111|M.gilvum_PYR-GCK D----VRWFDVEPCYVFHPMNAYDSPAD--DTIVLDVVR-----------
TH_3525|M.thermoresistible__bu R------IVHTEPLMHLHIANAYDDGADTVVELLNYDAS-----WTQLNA
MSMEG_1564|M.smegmatis_MC2_155 R------ILHTDPSLHLHLSNAYEDGEDTVVELVDYHSS-----WQELNG
MAV_3153|M.avium_104 R------VVETDPFYHWHFTNAYDDGDDVVVELPRFAPQTYAGMKNYTAH
Mvan_0203|M.vanbaalenii_PYR-1 R------RIECEAVLQFHLSNAFDDGDDVVIDAITYADG----------R
.. :. * *.:.. :
Mb0673|M.bovis_AF2122/97 YSRMFDRDRRGPGGDSRPSLDRWTINLATGAVTAECRDDRAQEFPRINET
Rv0654|M.tuberculosis_H37Rv YSRMFDRDRRGPGGDSRPSLDRWTINLATGAVTAECRDDRAQEFPRINET
MMAR_0993|M.marinum_M YRRMFDRDRRGPG-DTTPSLDRWVINLTTGAVSTECRDDRSQEFPRINET
MUL_0744|M.ulcerans_Agy99 YRRMFDRDRRGPG-DTSPSLDRWVINLTTGAVSTECRDDRSQEFPRINET
MAB_3874c|M.abscessus_ATCC_199 YDSMFSQDVLGPS-DAKGQLDRWTIDLAKGTVHMERKDDRHLEFPRINET
Mflv_2111|M.gilvum_PYR-GCK HPKMFDTDHLGPN-EGPPTLERWTVDLVAGKVRESRVDDRAQEFPRVDER
TH_3525|M.thermoresistible__bu QLLTVDGTVPDTTMPYGGVLRRIRITRS-GRVIHEPLTDLRGDFPMLNPR
MSMEG_1564|M.smegmatis_MC2_155 QLSLVPTLAQTATMPYGGQLTRLRITPS-GHVSREPITDLYGEFPMLNVK
MAV_3153|M.avium_104 IRSDIAQVDDYGAIEDAVVLTRFRIAAS-GRVTREPLADFGCEFPQIDPR
Mvan_0203|M.vanbaalenii_PYR-1 LLERIARFHTTSLADMPSQFTRFRVGAT-GRVGAEPLTDSPSEFPRHHPA
. : * : * * . * :** .
Mb0673|M.bovis_AF2122/97 LVGGPHRFAYTVGIEGGFLVGAGAALSTPLYKQDCVTGSSTVASLD-PDL
Rv0654|M.tuberculosis_H37Rv LVGGPHRFAYTVGIEGGFLVGAGAALSTPLYKQDCVTGSSTVASLD-PDL
MMAR_0993|M.marinum_M LLGKRHRFGYTLGVDGGYLTGGTSDMSTSLYKQDYATGSSQVAPLD-SDL
MUL_0744|M.ulcerans_Agy99 LLGKRHRFGYTLGVDGGYLTGGTSDMSTSLYKQDYATGSSQVAPLD-PDL
MAB_3874c|M.abscessus_ATCC_199 FTGKKHRYGYLPDVEN--FFGSGEAAGASIVKYDYETGSTLSSRLD-PAI
Mflv_2111|M.gilvum_PYR-GCK RVGKRHRYGYAP------CVGDG-TGDDELLKHDLVGGNSLTRAFG-NGK
TH_3525|M.thermoresistible__bu VSGRRHRYTYLV------VGVEGSTYPNAVAKLDHHTGASTLHRLP-PGH
MSMEG_1564|M.smegmatis_MC2_155 TMASQNRYTYLS------AALGGNIYPNAVAKIDNTTGKETVYRLP-DGH
MAV_3153|M.avium_104 RGTMRHHVSYLT------VQDPAKFPGQGIARVDHRTGEAQTYCPP--GH
Mvan_0203|M.vanbaalenii_PYR-1 REGRPHRYAYVN------TRRTLGTLYDTVTKLDLADQTELSYPAPEPGN
:: * : : *
Mb0673|M.bovis_AF2122/97 LIGEMVFVPNPSARAEDDGILMGYGWHRGRDEGQLLLLDAQTLES--IAT
Rv0654|M.tuberculosis_H37Rv LIGEMVFVPNPSARAEDDGILMGYGWHRGRDEGQLLLLDAQTLES--IAT
MMAR_0993|M.marinum_M LLGEMAFVPSPTAAAEDDGVLMGYGYHRGSDEGQLVLLDAQTLEL--AAC
MUL_0744|M.ulcerans_Agy99 LLGEMAFVPSPTAAAEDHGVLMGYGYHRGSDEGQLVLLDAQTLEL--AAC
MAB_3874c|M.abscessus_ATCC_199 VLGEMSFVPNPTCAAEDDGVLIGFAVDRRSDEGQLLLLDATSLDL--MAT
Mflv_2111|M.gilvum_PYR-GCK VAGEFVFHPSSPDAAEDDGVLMGYVYDRTTDRSELAILDAATLED--VAT
TH_3525|M.thermoresistible__bu LAHEPVFIPRPGGAAEDDGWLAVVVQDCHRHRAHLRLLDAGAVSADPVFT
MSMEG_1564|M.smegmatis_MC2_155 LPHEAIFAAHPDGVDEDDGWLLVPVIDGVENIASLIILDAKDIEAGPVYQ
MAV_3153|M.avium_104 VLVEPIFVPRPGGTAEDDGWLLTVGYDESRHRSRLMVVDAAHVADGPVAE
Mvan_0203|M.vanbaalenii_PYR-1 SFCEPVFAPRPGATAEDDGWLLTVEYRAAHKTSRLVILDAADPSRGPVAT
* * . . **.* * . . * ::**
Mb0673|M.bovis_AF2122/97 VHLPQRVPMGFHGNWAPTT-----
Rv0654|M.tuberculosis_H37Rv VHLPQRVPMGFHGNWAPTT-----
MMAR_0993|M.marinum_M VHLPQRVPLGFHGNWSAST-----
MUL_0744|M.ulcerans_Agy99 VHLPQRVPLGFHGNWSAST-----
MAB_3874c|M.abscessus_ATCC_199 VHLPQRVPAGFHGNWAPR------
Mflv_2111|M.gilvum_PYR-GCK VKLPHRVPSGFHGNWVPTA-----
TH_3525|M.thermoresistible__bu GHLRHSMPLTFHGCFTPRVGRSG-
MSMEG_1564|M.smegmatis_MC2_155 GRLRHHLPLTFHGCYTPRVAAPA-
MAV_3153|M.avium_104 AWLQFHVPMSYHGTFTTRVAQRTG
Mvan_0203|M.vanbaalenii_PYR-1 AQLASHIPQGFHGNFSARTS----
* :* :** : .