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NAPDARRGGLEVWAPSVVPPIGVELSDEQALAVAFRHLAGIGFAENMAGHITWQRDGRTDMFVNPWGLWW QEITASDICVVDGDARVVRGRWDVTPAIHIHTELHRVRDDARVVIHNHPYYVCVLAALGTLPELVHQTGS LFLDDLCLVDTYDGEIDTPARAADLAARIGGANLTILANHGVIATGRNLPEAVYRAASIERVCKLAYDVM LTGREPVSMNWSDMAGMQRSLIERAADVYWAGAARMTIKADPDVLQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2994 | - | - | 100% (257) | putative class II aldolase |
| M. avium 104 | MAV_3452 | - | 8e-18 | 27.51% (189) | hypothetical protein MAV_3452 |
| M. avium 104 | MAV_4439 | - | 5e-10 | 23.04% (217) | L-fuculose-phosphate aldolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0748c | fucA | 3e-10 | 23.94% (213) | L-fuculose-phosphate aldolase |
| M. gilvum PYR-GCK | Mflv_0622 | - | 2e-05 | 25.48% (208) | class II aldolase/adducin family protein |
| M. tuberculosis H37Rv | Rv0727c | fucA | 3e-10 | 23.94% (213) | L-fuculose-phosphate aldolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2912c | - | 3e-21 | 32.43% (185) | aldolase |
| M. marinum M | MMAR_2617 | araD | 1e-134 | 87.89% (256) | ribulose-5-phosphate 4-epimerase, AraD |
| M. smegmatis MC2 155 | MSMEG_6863 | - | 2e-14 | 28.11% (249) | hypothetical protein MSMEG_6863 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3144 | araD | 1e-134 | 87.89% (256) | ribulose-5-phosphate 4-epimerase, AraD |
| M. vanbaalenii PYR-1 | Mvan_0451 | - | 8e-18 | 26.72% (232) | hypothetical protein Mvan_0451 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2617|M.marinum_M -----------------MNAPDARQGGLQVWAPSVIPPIGVELSDAQALA
MUL_3144|M.ulcerans_Agy99 MPKGSFATIFEPGWRPSMNAPDARQGGLQVWAPSVIPPIGVELSDAQALA
MAV_2994|M.avium_104 -----------------MNAPDARRGGLEVWAPSVVPPIGVELSDEQALA
MAB_2912c|M.abscessus_ATCC_199 -----MTSGNVVAGEELSAYMVGSADGVQLGPAAAETVTQERERRLRELA
MSMEG_6863|M.smegmatis_MC2_155 ------------------------MKMEQRSPAPTEAELR------RELA
Mb0748c|M.bovis_AF2122/97 ---------------------------MNFVDDPES-----------AVL
Rv0727c|M.tuberculosis_H37Rv ---------------------------MNFVDAPES-----------AVL
Mvan_0451|M.vanbaalenii_PYR-1 --------MTSTMHDSKSDLMRRALDGLSRNVTESSLTLR------EKLA
Mflv_0622|M.gilvum_PYR-GCK ---------------------------MSSTPSGAGLDTER-----HAIA
. :
MMAR_2617|M.marinum_M VAFRHLAGIGFAENMAGHITWQ-PDGQTDMLVN---PWGLWWQELTASDI
MUL_3144|M.ulcerans_Agy99 VAFRHLAGIGFAENMAGHITWQ-PDGQTDMLVN---PWGLWWQELTASDI
MAV_2994|M.avium_104 VAFRHLAGIGFAENMAGHITWQ-RDGRTDMFVN---PWGLWWQEITASDI
MAB_2912c|M.abscessus_ATCC_199 AAFRIFGTFGFSEGVAGHITVRDPEFPDTFWVN---PFGMNFRHITVSDL
MSMEG_6863|M.smegmatis_MC2_155 AVYRLVAHYRMTDLVFTHISVRLPGNDHHFLIN---PYGLLFEEITASSL
Mb0748c|M.bovis_AF2122/97 AAAKDMLRRGLVEGTAGNISAR--RSDGNVVIT---PSSVDYAEMLLHDL
Rv0727c|M.tuberculosis_H37Rv AAAKDMLRRGLVEGTAGNISAR--RSDGNVVIT---PSSVDYAEMLLHDL
Mvan_0451|M.vanbaalenii_PYR-1 VTCRALFDAGHDSGLAGQITAR-AEAPGTYYTQ---RLGLGFDEITAGNL
Mflv_0622|M.gilvum_PYR-GCK LACRVLAARDLAPGILGHISLRVDRDRLLIRCRGPRERGLAFTSAEDIRM
. : . :*: : .: : :
MMAR_2617|M.marinum_M CTVDADARVVKGR---WDVTPAIHIHTQLHRVRDDARVVIHNHPYYVCVL
MUL_3144|M.ulcerans_Agy99 CTVDADARVVKGR---WDVTPAIHIHTQLHRVRDDARVVIHNHPYYVCVL
MAV_2994|M.avium_104 CVVDGDARVVRGR---WDVTPAIHIHTELHRVRDDARVVIHNHPYYVCVL
MAB_2912c|M.abscessus_ATCC_199 IQVDHDGNVITGS-R-PVNRAAFCIHSEVHKARPDVIAAAHAHSVHGKAF
MSMEG_6863|M.smegmatis_MC2_155 VRVDLNGNVIGETPY-CVNPAGFVIHSAIHAAREDAACVLHTHTLAGCAV
Mb0748c|M.bovis_AF2122/97 VLVDAGGAVLHAKDG-RSPSTELNLHLACYRAFDDIGSVIHSHPVWATMF
Rv0727c|M.tuberculosis_H37Rv VLVDAGGAVLHAKDG-RSPSTELNLHLACYRAFDDIGSVIHSHPVWATMF
Mvan_0451|M.vanbaalenii_PYR-1 LLVDEDLKVLDGE---GMANPANRFHSWIYRARPDVNCIVHTHPFHVAAL
Mflv_0622|M.gilvum_PYR-GCK VTLDGTAGGKGELDDGYQPPNELPLHTEVLRTRRDVNAVVHAHPEAVVAA
:* :* . * * *.
MMAR_2617|M.marinum_M AALGRLPDLVH--QTGSLFLDDMCLVESYDG--EIDSAARAADLAAHIGS
MUL_3144|M.ulcerans_Agy99 AALGRLPDLVH--QTGSLFLDDMCLVESYDG--EIDSAARAADLAAHIGS
MAV_2994|M.avium_104 AALGTLPELVH--QTGSLFLDDLCLVDTYDG--EIDTPARAADLAARIGG
MAB_2912c|M.abscessus_ATCC_199 SSLGQPLLPIT--QDACAFYQDHAVYTDYRG--VVGDLEEGRAIGSALGP
MSMEG_6863|M.smegmatis_MC2_155 AASASGLLPVN--QISMEFFN-RVGYHDYEG--VALNLDEQKRLVEDLGT
Mb0748c|M.bovis_AF2122/97 AVAHEPIPACI--DEFAIYCGGDVRCTEYA---ASGTPEVGRNAVRALEG
Rv0727c|M.tuberculosis_H37Rv AVAHEPIPACI--DEFAIYCGGDVRCTEYA---ASGTPEVGRNAVRALEG
Mvan_0451|M.vanbaalenii_PYR-1 SMLEVPLVVSQ--MDIAPLYGDCAFLPDWPG--VPVGNEEGEIISAALGD
Mflv_0622|M.gilvum_PYR-GCK DLAGLAVRPIVGAFDIPGFRLAAAGVPVYRRGVLVRNRQLAQEMVAAMAD
: :
MMAR_2617|M.marinum_M ANLTILANHGVIATGRNLAQAVYRAASIERVCKLAYDVMLTGA----EPT
MUL_3144|M.ulcerans_Agy99 ANLTILANHGVIATGRNLAQAVYRAASIEQVCKLAYDVMLTGA----EPT
MAV_2994|M.avium_104 ANLTILANHGVIATGRNLPEAVYRAASIERVCKLAYDVMLTGR----EPV
MAB_2912c|M.abscessus_ATCC_199 AKAVILQNHGLLTVGHSVAEAAWWFITMERSCQAQLLAMAAGE-----PR
MSMEG_6863|M.smegmatis_MC2_155 HDALILRNHGLLTVGATPARAFLRMYYLNKACEIQIAASQLGELVIPDPR
Mb0748c|M.bovis_AF2122/97 RAAALIANHGLVAVGPRPDQVLRVTALVERTAQIVWGARALGG-----PV
Rv0727c|M.tuberculosis_H37Rv RAAALIANHGLVAVGPRPDQVLRVTALVERTAQIVWGARALGG-----PV
Mvan_0451|M.vanbaalenii_PYR-1 KKAILLAHHGHVVAGASVEEACSLAMLVERGAKLQLAAMAAGT-----IA
Mflv_0622|M.gilvum_PYR-GCK RPVVVLRAHGLTSAADTVERAVLQAISVDTISRLSLQIASAGG----TLA
:: ** .. .. :: .. *
MMAR_2617|M.marinum_M QMKWSDMAAMRSSLIERAADVY-----WAGAARMTIKADPAVLS--
MUL_3144|M.ulcerans_Agy99 QMKWSDMAGMRSSLIERAADVY-----WAGAARMTIKADPAVLS--
MAV_2994|M.avium_104 SMNWSDMAGMQRSLIERAADVY-----WAGAARMTIKADPDVLQ--
MAB_2912c|M.abscessus_ATCC_199 TIDHDTAVSVYNQIGTPVAGWFQFQPLWDDVIRTAPEALH------
MSMEG_6863|M.smegmatis_MC2_155 IIEHAAQQLVGDAAGDDYTDDVGYDLAWAAMVRMLDRTQPDYRD--
Mb0748c|M.bovis_AF2122/97 PIPEDVCRNFTGVYGYLRANPL------------------------
Rv0727c|M.tuberculosis_H37Rv PIPEDVCRNFTGVYGYLRANPL------------------------
Mvan_0451|M.vanbaalenii_PYR-1 PLPDRLAREAHDWTLTPKRSQAN----FAYYARRALANHPDALDR-
Mflv_0622|M.gilvum_PYR-GCK DLPDADAAELP-DLGNAFNETIAWRHELARLETHGLSCHPSEKRSS
: