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TSGNVVAGEELSAYMVGSADGVQLGPAAAETVTQERERRLRELAAAFRIFGTFGFSEGVAGHITVRDPEF PDTFWVNPFGMNFRHITVSDLIQVDHDGNVITGSRPVNRAAFCIHSEVHKARPDVIAAAHAHSVHGKAFS SLGQPLLPITQDACAFYQDHAVYTDYRGVVGDLEEGRAIGSALGPAKAVILQNHGLLTVGHSVAEAAWWF ITMERSCQAQLLAMAAGEPRTIDHDTAVSVYNQIGTPVAGWFQFQPLWDDVIRTAPEALH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2912c | - | - | 100% (271) | aldolase |
| M. abscessus ATCC 19977 | MAB_1048c | - | 1e-28 | 39.47% (190) | class II aldolase/adducin domain protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0748c | fucA | 4e-10 | 27.05% (207) | L-fuculose-phosphate aldolase |
| M. gilvum PYR-GCK | Mflv_0622 | - | 4e-05 | 25.25% (198) | class II aldolase/adducin family protein |
| M. tuberculosis H37Rv | Rv0727c | fucA | 5e-10 | 27.05% (207) | L-fuculose-phosphate aldolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2153 | - | 2e-28 | 34.05% (232) | hypothetical protein MMAR_2153 |
| M. avium 104 | MAV_3452 | - | 2e-28 | 34.68% (248) | hypothetical protein MAV_3452 |
| M. smegmatis MC2 155 | MSMEG_6863 | - | 8e-33 | 36.52% (230) | hypothetical protein MSMEG_6863 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3144 | araD | 3e-21 | 30.16% (189) | ribulose-5-phosphate 4-epimerase, AraD |
| M. vanbaalenii PYR-1 | Mvan_0451 | - | 4e-28 | 34.02% (244) | hypothetical protein Mvan_0451 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0748c|M.bovis_AF2122/97 --------------------MNFVDDPE------------------SAVL
Rv0727c|M.tuberculosis_H37Rv --------------------MNFVDAPE------------------SAVL
MAB_2912c|M.abscessus_ATCC_199 -MTSGNVVAGEELSAYMVGSADGVQLGP----AAAETVTQERERRLRELA
MSMEG_6863|M.smegmatis_MC2_155 --------------------MKMEQRSP----APTEAELR------RELA
MMAR_2153|M.marinum_M ----MATTFSDSKSELMRRAQERLDAQT----PESQLTTR------QKVA
MAV_3452|M.avium_104 ----MASTFTDSKSELMRRAAEQLTALQGRDAAESPLTTR------QKLA
Mvan_0451|M.vanbaalenii_PYR-1 ----MTSTMHDSKSDLMRRALDGLSRNV----TESSLTLR------EKLA
MUL_3144|M.ulcerans_Agy99 MPKGSFATIFEPGWRPSMNAPDARQGGLQVWAPSVIPPIGVELSDAQALA
Mflv_0622|M.gilvum_PYR-GCK --------------MSSTPSGAGLDTER------------------HAIA
:
Mb0748c|M.bovis_AF2122/97 AAAKDMLRRGLVEGTAGNISAR--RSDGNVVIT---PSSVDYAEMLLHDL
Rv0727c|M.tuberculosis_H37Rv AAAKDMLRRGLVEGTAGNISAR--RSDGNVVIT---PSSVDYAEMLLHDL
MAB_2912c|M.abscessus_ATCC_199 AAFRIFGTFGFSEGVAGHITVRDPEFPDTFWVN---PFGMNFRHITVSDL
MSMEG_6863|M.smegmatis_MC2_155 AVYRLVAHYRMTDLVFTHISVRLPGNDHHFLIN---PYGLLFEEITASSL
MMAR_2153|M.marinum_M LTCRVLFDAGHDSGLAGQITAR-AQRPGTYYTQ---QLGLGFDEITEDNL
MAV_3452|M.avium_104 LTCRALFDAGHDSGLAGQITAR-AEADGTYYTQ---RLGLGFDEITDGNL
Mvan_0451|M.vanbaalenii_PYR-1 VTCRALFDAGHDSGLAGQITAR-AEAPGTYYTQ---RLGLGFDEITAGNL
MUL_3144|M.ulcerans_Agy99 VAFRHLAGIGFAENMAGHITWQ-PDGQTDMLVN---PWGLWWQELTASDI
Mflv_0622|M.gilvum_PYR-GCK LACRVLAARDLAPGILGHISLRVDRDRLLIRCRGPRERGLAFTSAEDIRM
. : . :*: : .: : :
Mb0748c|M.bovis_AF2122/97 VLVDAGGAVLHAKDGRSPST-ELNLHLACYRAFDDIGSVIHSH--PVWAT
Rv0727c|M.tuberculosis_H37Rv VLVDAGGAVLHAKDGRSPST-ELNLHLACYRAFDDIGSVIHSH--PVWAT
MAB_2912c|M.abscessus_ATCC_199 IQVDHDGNVITGS-RPVNRA-AFCIHSEVHKARPDVIAAAHAH--SVHGK
MSMEG_6863|M.smegmatis_MC2_155 VRVDLNGNVIGETPYCVNPA-GFVIHSAIHAAREDAACVLHTH--TLAGC
MMAR_2153|M.marinum_M LLVDEDLNVLEGS--AMANP-ANRFHSWIYRERPDVQCIVHTH--GFHTA
MAV_3452|M.avium_104 LLVDEDLNVLEGD--GMANP-ANRFHSWIYRARPDVQCIVHTH--AFHVA
Mvan_0451|M.vanbaalenii_PYR-1 LLVDEDLKVLDGE--GMANP-ANRFHSWIYRARPDVNCIVHTH--PFHVA
MUL_3144|M.ulcerans_Agy99 CTVDADARVVKGR--WDVTP-AIHIHTQLHRVRDDARVVIHNH--PYYVC
Mflv_0622|M.gilvum_PYR-GCK VTLDGTAGGKGELDDGYQPPNELPLHTEVLRTRRDVNAVVHAHPEAVVAA
:* . :* * * *
Mb0748c|M.bovis_AF2122/97 MFAVAHEPIPACIDEFAIYCGGDVRCTEYAA--SGTP-EVGRNAVRALEG
Rv0727c|M.tuberculosis_H37Rv MFAVAHEPIPACIDEFAIYCGGDVRCTEYAA--SGTP-EVGRNAVRALEG
MAB_2912c|M.abscessus_ATCC_199 AFSSLGQPLLPITQDACAFYQDHAVYTDYRG--VVGDLEEGRAIGSALGP
MSMEG_6863|M.smegmatis_MC2_155 AVAASASGLLPVNQISMEFFN-RVGYHDYEG--VALNLDEQKRLVEDLGT
MMAR_2153|M.marinum_M ALSMLKVPLIVSHMDTTPLYDDCAFLADWPG--VPVGNEEGEIISAALGN
MAV_3452|M.avium_104 ALSMLEVPLVVSHMDTTPLYDDCAFLADWPG--VPVGNEEGEIITAALGD
Mvan_0451|M.vanbaalenii_PYR-1 ALSMLEVPLVVSQMDIAPLYGDCAFLPDWPG--VPVGNEEGEIISAALGD
MUL_3144|M.ulcerans_Agy99 VLAALGRLPDLVHQTGSLFLDDMCLVESYDG--EIDSAARAADLAAHIGS
Mflv_0622|M.gilvum_PYR-GCK DLAGLAVRPIVGAFDIPGFRLAAAGVPVYRRGVLVRNRQLAQEMVAAMAD
.: : :
Mb0748c|M.bovis_AF2122/97 RAAALIANHGLVAVGPRPDQVLRVTALVERTAQIVWGARALGG-----PV
Rv0727c|M.tuberculosis_H37Rv RAAALIANHGLVAVGPRPDQVLRVTALVERTAQIVWGARALGG-----PV
MAB_2912c|M.abscessus_ATCC_199 AKAVILQNHGLLTVGHSVAEAAWWFITMERSCQAQLLAMAAGE-----PR
MSMEG_6863|M.smegmatis_MC2_155 HDALILRNHGLLTVGATPARAFLRMYYLNKACEIQIAASQLGELVIPDPR
MMAR_2153|M.marinum_M KKAILLAHHGQLIAGISIEEACTLAVLIERAAKLQLAAMSAGT-----IA
MAV_3452|M.avium_104 KKAVLLAHHGHVIAGASIEEACSLGILIERAAKLQLAAMAAGT-----VK
Mvan_0451|M.vanbaalenii_PYR-1 KKAILLAHHGHVVAGASVEEACSLAMLVERGAKLQLAAMAAGT-----IA
MUL_3144|M.ulcerans_Agy99 ANLTILANHGVIATGRNLAQAVYRAASIEQVCKLAYDVMLTGA-----EP
Mflv_0622|M.gilvum_PYR-GCK RPVVVLRAHGLTSAADTVERAVLQAISVDTISRLSLQIASAGG-TLADLP
:: ** .. .. :: .. *
Mb0748c|M.bovis_AF2122/97 PIPEDVCRNFTGVYGYLRANPL----------------------
Rv0727c|M.tuberculosis_H37Rv PIPEDVCRNFTGVYGYLRANPL----------------------
MAB_2912c|M.abscessus_ATCC_199 TIDHDTAVSVYNQIGTPVAGWFQFQPLWDDVIRTAPEALH----
MSMEG_6863|M.smegmatis_MC2_155 IIEHAAQQLVGDAAGDDYTDDVGYDLAWAAMVRMLDRTQPDYRD
MMAR_2153|M.marinum_M ELPDQLAREAHDWTLTPSRSRANFAYYARRALARHPDALSS---
MAV_3452|M.avium_104 QLPEELAREAHDWTLSPQRSRANFAYYARRALARHPDALTS---
Mvan_0451|M.vanbaalenii_PYR-1 PLPDRLAREAHDWTLTPKRSQANFAYYARRALANHPDALDR---
MUL_3144|M.ulcerans_Agy99 TQMKWSDMAGMRSSLIERAADVYWAGAARMTIKADPAVLS----
Mflv_0622|M.gilvum_PYR-GCK DADAAELPDLGNAFNETIAWRHELARLETHGLSCHPSEKRSS--