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NFVDAPESAVLAAAKDMLRRGLVEGTAGNISARRSDGNVVITPSSVDYAEMLLHDLVLVDAGGAVLHAKD GRSPSTELNLHLACYRAFDDIGSVIHSHPVWATMFAVAHEPIPACIDEFAIYCGGDVRCTEYAASGTPEV GRNAVRALEGRAAALIANHGLVAVGPRPDQVLRVTALVERTAQIVWGARALGGPVPIPEDVCRNFTGVYG YLRANPL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0727c | fucA | - | 100% (218) | L-fuculose-phosphate aldolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0748c | fucA | 1e-124 | 99.54% (218) | L-fuculose-phosphate aldolase |
| M. gilvum PYR-GCK | Mflv_0622 | - | 7e-07 | 22.77% (202) | class II aldolase/adducin family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1048c | - | 3e-11 | 25.76% (198) | class II aldolase/adducin domain protein |
| M. marinum M | MMAR_1064 | fucA | 1e-107 | 85.32% (218) | L-fuculose-1-phosphate aldolase FucA |
| M. avium 104 | MAV_4439 | - | 1e-104 | 82.49% (217) | L-fuculose-phosphate aldolase |
| M. smegmatis MC2 155 | MSMEG_1714 | - | 7e-23 | 34.62% (208) | L-ribulose-5-phosphate 4-epimerase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0822 | fucA | 1e-107 | 85.32% (218) | L-fuculose-phosphate aldolase |
| M. vanbaalenii PYR-1 | Mvan_0451 | - | 2e-11 | 27.32% (183) | hypothetical protein Mvan_0451 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0727c|M.tuberculosis_H37Rv ------------------------MNFVDAPESAVLAAAKDMLRRGLVEG
Mb0748c|M.bovis_AF2122/97 ------------------------MNFVDDPESAVLAAAKDMLRRGLVEG
MMAR_1064|M.marinum_M ------------------------MKFVDNAQVAVLAAAKDMLRRGLVEG
MUL_0822|M.ulcerans_Agy99 ------------------------MKFVDNAQVAVLAAAKDMLRRGLVEG
MAV_4439|M.avium_104 ------------------------MKFVDDPEQAVLDAAKDMLRRGLVEG
MSMEG_1714|M.smegmatis_MC2_155 -----------------MSVTTEIDAVIRQLRKQVCDLHAELTRYQLVIW
MAB_1048c|M.abscessus_ATCC_199 MASTLHDTKSELMDRAERSMQTHFSDSQWTTRQKVALTCRALFDRGHDSG
Mvan_0451|M.vanbaalenii_PYR-1 MTSTMHDSKSDLMRRALDGLSRNVTESSLTLREKLAVTCRALFDAGHDSG
Mflv_0622|M.gilvum_PYR-GCK ------------------MSSTPSGAGLDTERHAIALACRVLAARDLAPG
. : :
Rv0727c|M.tuberculosis_H37Rv TAGNISARRSDGNVVIT-----PSSVDYAEMLLHDLVLVD-AGGAVLHAK
Mb0748c|M.bovis_AF2122/97 TAGNISARRSDGNVVIT-----PSSVDYAEMLLHDLVLVD-AGGAVLHAK
MMAR_1064|M.marinum_M TAGNISARCADGNLVIT-----PSSVDYADMTLDDLVQVD-ADGTVLHAK
MUL_0822|M.ulcerans_Agy99 TAGNISARCADGNLVIT-----PSSVDYADMTLDDLVQVD-ADGTVLHAK
MAV_4439|M.avium_104 TAGNISARRSDGNIVIT-----PSSVDYRDMQLDDLVLID-PAGSVLQAA
MSMEG_1714|M.smegmatis_MC2_155 TAGNVSARVPDRDLMIIK----PSGVDYDSMTPEQMVVCD-LHGELVDG-
MAB_1048c|M.abscessus_ATCC_199 LAGQITARAEEPGTFYTQ----RLGLGFDEITEENLLLVD-EDLNVLEGS
Mvan_0451|M.vanbaalenii_PYR-1 LAGQITARAEAPGTYYTQ----RLGLGFDEITAGNLLLVD-EDLKVLDGE
Mflv_0622|M.gilvum_PYR-GCK ILGHISLRVDRDRLLIRCRGPRERGLAFTSAEDIRMVTLDGTAGGKGELD
*::: * .: : . :: * .
Rv0727c|M.tuberculosis_H37Rv DGRSPSTELNLHLACYRAFDDIGSVIHSHPVWATMFAVAHEPIP--ACID
Mb0748c|M.bovis_AF2122/97 DGRSPSTELNLHLACYRAFDDIGSVIHSHPVWATMFAVAHEPIP--ACID
MMAR_1064|M.marinum_M AGRAPSTEMHLHLACYQAFDDIGSVIHSHPVWATMFAIAHQPIP--ACID
MUL_0822|M.ulcerans_Agy99 AGRAPSTEMHLHLACYQAFDDIGSVIHSHPVWATMFAIAHQPIP--ACID
MAV_4439|M.avium_104 QGRSPSTEMQLHLACFAAFDDIGCVIHSHPVWATMFAIAHQSIP--ACID
MSMEG_1714|M.smegmatis_MC2_155 -DLAPSSDTAAHAYVYRHMPEVGGVVHTHSTYATAWAARGEAIP--CVLT
MAB_1048c|M.abscessus_ATCC_199 GMANPAN--RFHSWIYRARPDVQCIVHTHPFHVAALSMLETPLI--VSQM
Mvan_0451|M.vanbaalenii_PYR-1 GMANPAN--RFHSWIYRARPDVNCIVHTHPFHVAALSMLEVPLV--VSQM
Mflv_0622|M.gilvum_PYR-GCK DGYQPPNELPLHTEVLRTRRDVNAVVHAHPEAVVAADLAGLAVRPIVGAF
*.. * :: ::*:*. .. .:
Rv0727c|M.tuberculosis_H37Rv EFAIYCGGDVRCTEYAA---SGTPEVGRNAVRALEGRA--AALIANHGLV
Mb0748c|M.bovis_AF2122/97 EFAIYCGGDVRCTEYAA---SGTPEVGRNAVRALEGRA--AALIANHGLV
MMAR_1064|M.marinum_M EFAVYCGGDVRCAEYAA---SGTPEVGRNAVAALQGRA--AALIANHGLV
MUL_0822|M.ulcerans_Agy99 EFAVYCGGDVRCAEYAA---SGTPEVGRNAVAALQGRA--AALIANHGLV
MAV_4439|M.avium_104 EFAVYCGGDVRCAEYAA---SGSPDVGANAVKALQGRG--AALIANHGLV
MSMEG_1714|M.smegmatis_MC2_155 MIADEFGGDIPVGPFAL---IGDDSIGRGIVETLQHSNSRAVLMRNHGPF
MAB_1048c|M.abscessus_ATCC_199 DIAPLYDDCAFLPDWPG---VPVGNEEGEIISAALGDK-KAILLAHHGHV
Mvan_0451|M.vanbaalenii_PYR-1 DIAPLYGDCAFLPDWPG---VPVGNEEGEIISAALGDK-KAILLAHHGHV
Mflv_0622|M.gilvum_PYR-GCK DIPGFRLAAAGVPVYRRGVLVRNRQLAQEMVAAMADRP--VVVLRAHGLT
:. : . : : . :: **
Rv0727c|M.tuberculosis_H37Rv AVGPRPDQVLRVTALVERTAQIVWGARALG-GPVPIPEDVC---------
Mb0748c|M.bovis_AF2122/97 AVGPRPDQVLRVTALVERTAQIVWGARALG-GPVPIPEDVC---------
MMAR_1064|M.marinum_M AVGPRPDKVLHVTALVERTAQIVWGARALG-GPVPIPEDVN---------
MUL_0822|M.ulcerans_Agy99 AVGPRPDKVLHVTALVERTAQIVWGARALG-GPVPIPEDVN---------
MAV_4439|M.avium_104 AVGPRPDKVLHITALVERTAQIVWGARALG-GPVPIPEDVN---------
MSMEG_1714|M.smegmatis_MC2_155 TVGRDARDAVKAAVMVEDVARTVHISRQLG-TPDVIPPADV---------
MAB_1048c|M.abscessus_ATCC_199 VAGASVEESCSLAVLIERGAKLQLAAMAAG-TIAPLPDRLAREAHDWTLT
Mvan_0451|M.vanbaalenii_PYR-1 VAGASVEEACSLAMLVERGAKLQLAAMAAG-TIAPLPDRLAREAHDWTLT
Mflv_0622|M.gilvum_PYR-GCK SAADTVERAVLQAISVDTISRLSLQIASAGGTLADLPDADAAELPDLG--
.. : :: :: * :*
Rv0727c|M.tuberculosis_H37Rv -RNFTGVYGYLRANPL----------------
Mb0748c|M.bovis_AF2122/97 -RNFTGVYGYLRANPL----------------
MMAR_1064|M.marinum_M -RNFAGVYAYLRANPM----------------
MUL_0822|M.ulcerans_Agy99 -RNFAGVYAYLRANPM----------------
MAV_4439|M.avium_104 -RNFAAVYGYLRANP-----------------
MSMEG_1714|M.smegmatis_MC2_155 -RRLFDRYQNVYGQPQASQEG-----------
MAB_1048c|M.abscessus_ATCC_199 PKRSIANFAYYARTALAHHPETLTLPTTQGNS
Mvan_0451|M.vanbaalenii_PYR-1 PKRSQANFAYYARRALANHPDALDR-------
Mflv_0622|M.gilvum_PYR-GCK -NAFNETIAWRHELARLETHGLSCHPSEKRSS
. .