For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSSTGSARTEGDSWDLASSVGATATMVAASRALASRGPDPLLDDRFAEPLVRAVGHPFFVRMLDGQIPLD TDDMPMTLQQRREQITVRTRFFDDFFRSATAAGIRQAVILAAGLDARAYRLSWPAGTVVFEVDQPEVISF KTDTLARLGAQPTAERRTVAVDLRDDWPTALRDTGFDSSARTAWIAEGLLPYLPPHAQDRLLDNITALSA PGSRLATENITDMRVFTDERARAMRSTWRQHGLDIDVAELVWLGERRPAGDHLEATGWSVTRLPTERVYA DYGFELPDNEILREFRQAISYLSAELG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2732 | - | - | 100% (307) | methyltransferase |
| M. avium 104 | MAV_4442 | - | e-103 | 61.87% (299) | methyltransferase, putative, family protein |
| M. avium 104 | MAV_4444 | - | 1e-91 | 57.54% (285) | methyltransferase, putative, family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0752c | - | 5e-92 | 57.37% (312) | hypothetical protein Mb0752c |
| M. gilvum PYR-GCK | Mflv_5025 | - | 2e-91 | 57.28% (302) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv0731c | - | 6e-92 | 57.37% (312) | hypothetical protein Rv0731c |
| M. leprae Br4923 | MLBr_02640 | - | 1e-58 | 47.29% (277) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3787 | - | 4e-83 | 53.09% (307) | hypothetical protein MAB_3787 |
| M. marinum M | MMAR_1058 | - | 2e-93 | 59.38% (288) | O-methyltransferase |
| M. smegmatis MC2 155 | MSMEG_1480 | - | 5e-97 | 61.54% (299) | methyltransferase |
| M. thermoresistible (build 8) | TH_2706 | - | 8e-94 | 59.18% (294) | PUTATIVE putative methyltransferase |
| M. ulcerans Agy99 | MUL_0817 | - | 5e-91 | 57.99% (288) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1345 | - | 3e-90 | 62.11% (285) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5025|M.gilvum_PYR-GCK -----MARTPDDSWDLASSVGATATMVAAGRAVASAD----PDPLINDPY
TH_2706|M.thermoresistible__bu -----MARSESDTWDLTSGVGVTATMVAAARALASRE----PEPLIDDPF
MSMEG_1480|M.smegmatis_MC2_155 -----MTRTDGDTWDLATSVGSTATGVAAMRALATRQ----PDPLIDDPY
Mvan_1345|M.vanbaalenii_PYR-1 -----MARTEGDTWDLGSSVGATATSVAANRAFASRSTAGGPEPLLNDPY
MAV_2732|M.avium_104 MSSTGSARTEGDSWDLASSVGATATMVAASRALASRG----PDPLLDDRF
MMAR_1058|M.marinum_M MNR----RTDADSWDPASSVGATATMVAASRARASRG----PDALLDDRL
MUL_0817|M.ulcerans_Agy99 MNR----RTDADSWDPASSVGATATMVAASRARASRG----PDALLDDRL
Mb0752c|M.bovis_AF2122/97 MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRA----PGALVNDQF
Rv0731c|M.tuberculosis_H37Rv MTQTGSARFEGDSWDLASSVGLTATMVAAARAVAGRA----PGALVNDQF
MAB_3787|M.abscessus_ATCC_1997 -----MARTDDDSWDLASSVGATATMVAAQRALASHV----PNPLINDPY
MLBr_02640|M.leprae_Br4923 ------MRTHDDTWDIKTSVGTTAVMVAAARAAETDR----PDALIRDPY
* *:** :.** **. *** ** * .*: *
Mflv_5025|M.gilvum_PYR-GCK AEPLVRAVGL-DFFTRMLDGELDLSVFP--DSSPERAQAMIDGMAVRTRF
TH_2706|M.thermoresistible__bu AAPLVRAVGV-EFFTRLVDGDLELPADT--AEERAAAQVLTEVMAVRTRF
MSMEG_1480|M.smegmatis_MC2_155 ADALVKAVGL-EHCIALADGETCVEG----DPM-LDLNRMCEQIAVRTRY
Mvan_1345|M.vanbaalenii_PYR-1 ADLLVEAVGL-PHFIRVARGEIDFDD----DPL-FGARQMLEQITVRTRH
MAV_2732|M.avium_104 AEPLVRAVGH-PFFVRMLDGQIPLDT----DDMPMTLQQRREQITVRTRF
MMAR_1058|M.marinum_M AEPLVRAVGL-QPLVRMIDGDTAVD------DPPSSPRSLNEQIAVRTRY
MUL_0817|M.ulcerans_Agy99 AGPLVRAVGL-QPLVRMIDGDTAVD------DPPSSPRSLNEQIAVRTRY
Mb0752c|M.bovis_AF2122/97 AEPLVRAVGV-DFFVRMASGELDPDELA--EDEANGLRRFADAMAIRTHY
Rv0731c|M.tuberculosis_H37Rv AEPLVRAVGV-DFFVRMASGELDPDELA--EDEANGLRRFADAMAIRTHY
MAB_3787|M.abscessus_ATCC_1997 AEPLVRAVGI-EYFTKLASGAFDPEQMAGLVQLGITADGMANGMASRTWY
MLBr_02640|M.leprae_Br4923 AKLLVTNTGAGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNF
* ** .* : . : ** .
Mflv_5025|M.gilvum_PYR-GCK FDDCCLAAASAG---VRQVVILAAGLDARTYRLPWPDGTVVYELDQPDVI
TH_2706|M.thermoresistible__bu FDDFFTDATRVG---ARQAVILASGLDARAYRLTWPDGTVVYEIDQPEVI
MSMEG_1480|M.smegmatis_MC2_155 FDELFIAAGADG---VRQAVILASGLDTRAYRLDWPAGTVVFEVDQPQVI
Mvan_1345|M.vanbaalenii_PYR-1 FDDFFAGAMAAGPPKIRQAVILASGLDTRAYRLPWPAGTVVYEIDQPTVI
MAV_2732|M.avium_104 FDDFFRSATAAG---IRQAVILAAGLDARAYRLSWPAGTVVFEVDQPEVI
MMAR_1058|M.marinum_M FDDFFTAAGAGG---IRQAVILASGLDTRAYRLNWPSGMTVYEIDQPQVI
MUL_0817|M.ulcerans_Agy99 FDDFFTAAGAGG---IRQAVILASGLDTRAYRLNWPSGMTVYEIDQPQVI
Mb0752c|M.bovis_AF2122/97 FDNFFLDATRAG---IRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVI
Rv0731c|M.tuberculosis_H37Rv FDNFFLDATRAG---IRQAVILASGLDSRAYRLRWPAGTIVFEVDQPQVI
MAB_3787|M.abscessus_ATCC_1997 YDTAFESSTAAG---VRQAVILASGLDTRAYRLTWPAGTTVYELDQPEVI
MLBr_02640|M.leprae_Br4923 FDTYFNNAVIDG---IRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVL
:* : * ** ****:***:*:*** ** * *:*:*** *:
Mflv_5025|M.gilvum_PYR-GCK AFKTQTLRNLGAEPAATQRPVPVDLREDWPAALRAAGFDATRPTAWLAEG
TH_2706|M.thermoresistible__bu AFKTRTLAELGAPPTAPHRPVAVDLRDDWPAALTAAGFDPTVATAWSAEG
MSMEG_1480|M.smegmatis_MC2_155 EFKTRTLADLGAQPTAERRTVAVDLRDDWPAALRDAGFDPAEPTAWIAEG
Mvan_1345|M.vanbaalenii_PYR-1 EFKTAVLADAGVAPTAERRTVGIDLREDWPAALRGAGFDPTRPTAWIAEG
MAV_2732|M.avium_104 SFKTDTLARLGAQPTAERRTVAVDLRDDWPTALRDTGFDSSARTAWIAEG
MMAR_1058|M.marinum_M EFKTRTLAEFGALPCPDHRPIGIDLREDWPSALRQRGFDAGQPTAWIAEG
MUL_0817|M.ulcerans_Agy99 EFKTRTLAEFGALPCPDHRPIGIDLREDWPSALRQRGFDAGQPTAWIAEG
Mb0752c|M.bovis_AF2122/97 DFKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEG
Rv0731c|M.tuberculosis_H37Rv DFKTTTLAGLGAAPTTDRRTVAVDLRDDWPTALQKAGFDNAQRTAWIAEG
MAB_3787|M.abscessus_ATCC_1997 TFKTDTLAELGASPSAERRTVAIDLREDWPAALQAAGFDPEQPTVWSAEG
MLBr_02640|M.leprae_Br4923 AYKSTTLAEHGVTPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEG
:*: .* *. * . :* : :***:***.** *** *.* ***
Mflv_5025|M.gilvum_PYR-GCK LLIYLPPEAQDALFDTVTALSAPGSTLATEYVPGIVDFDGA----KARAL
TH_2706|M.thermoresistible__bu LLRYLPPDAQDRLFDHITDLSAPGSRLATEDHPGPGAGLGE----KADEL
MSMEG_1480|M.smegmatis_MC2_155 LLIYLPAEAQDRLLDNITALSAPGSRLATEHM-DHRILAEG----AGKRI
Mvan_1345|M.vanbaalenii_PYR-1 LLIYLPPDAQDRLLDHITALSAPGSRLATEHM-DAKALTGE----WARAM
MAV_2732|M.avium_104 LLPYLPPHAQDRLLDNITALSAPGSRLATENITDMRVFTDE----RARAM
MMAR_1058|M.marinum_M LLVYLPPEAQDRLFDNIAELSTPGSQVATEHFPDPNGFSGP----RAQRL
MUL_0817|M.ulcerans_Agy99 LLVYLPPEAQDRLFDNIAELSTPRSQVATEHFPDPNGFSGP----RAQRL
Mb0752c|M.bovis_AF2122/97 LLGYLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMRRL
Rv0731c|M.tuberculosis_H37Rv LLGYLSAEAQDRLLDQITAQSVPGSQFATEVLRDINRLNEEELRGRMRRL
MAB_3787|M.abscessus_ATCC_1997 LLIYLPPEAQDRLFASITELSAPGSRLVCEQVPGLETADFS----KAREL
MLBr_02640|M.leprae_Br4923 LLMYLPATAQDGLFTEIGGLSAVGSRIAVETSPLHGDEWREQMQLRFRRV
** **.. *** *: : *. * .. * :
Mflv_5025|M.gilvum_PYR-GCK SEPLREHGLDIDMPSLVYTGA-RTPVMDHLRGAGWQVSGTARAELFARFG
TH_2706|M.thermoresistible__bu GRRWREHGFEVQLSELFHPGE-RTPVVDYLRGRGWDARARPRAEVFAGYG
MSMEG_1480|M.smegmatis_MC2_155 GEWSRRVGSSLDIADLFYTGE-RNTAGDYLRGLGWQVTVRPSKEAYADHG
Mvan_1345|M.vanbaalenii_PYR-1 TERARRHGSDVNLSELFYSGP-RTSATEHLRAQGWQTEVLSSNDAYQAQG
MAV_2732|M.avium_104 RSTWRQHGLDIDVAELVWLGE-RRPAGDHLEATGWSVTRLPTERVYADYG
MMAR_1058|M.marinum_M SERWRRMGLDLDMAELIYHGD-RNTVIDYLADHGWRVRARTFEEMHAHNG
MUL_0817|M.ulcerans_Agy99 SERWHRMGMDLDMAELIYHGD-RNTVIDYLADHGWRVRARTFEEMHAHNG
Mb0752c|M.bovis_AF2122/97 AERFRRHGLDLDMSGLVYFGD-RTDARTYLADHGWRTASASTTDLLAEHG
Rv0731c|M.tuberculosis_H37Rv AERFRRHGLDLDMSGLVYFGD-RTDARTYLADHGWRTASASTTDLLAEHG
MAB_3787|M.abscessus_ATCC_1997 TRQFAGETLDLDLESLVYTQE-RQMAADWLAEHGWTVITEENDELYARLN
MLBr_02640|M.leprae_Br4923 SDALG-FEQAVDVQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVG
::: *. * . * ** . .
Mflv_5025|M.gilvum_PYR-GCK RPLPQDADGTDPLG--EIVYVSATLAADA----
TH_2706|M.thermoresistible__bu REFPDSAALAAMRDSSAVTAVRPVVRAGMR---
MSMEG_1480|M.smegmatis_MC2_155 FE-LPEEMA-ELSGD--SGYLSAHLK-------
Mvan_1345|M.vanbaalenii_PYR-1 FAPVADHLV-AMIGD--SGYLTARLD-------
MAV_2732|M.avium_104 FELPDNEILREFRQA--ISYLSAELG-------
MMAR_1058|M.marinum_M FEPPDDEMM-ALFGG--MSYVTGIRK-------
MUL_0817|M.ulcerans_Agy99 FEPPDDEMM-ALFGG--MSYVTGIRK-------
Mb0752c|M.bovis_AF2122/97 LPPIDGDD--APFGE--VIYVSAELKQKHQDTR
Rv0731c|M.tuberculosis_H37Rv LPPIDGDD--APFGE--VIYVSAELKQKHQDTR
MAB_3787|M.abscessus_ATCC_1997 LDPPNPLLR-SIFPN--IVYVDATLG-------
MLBr_02640|M.leprae_Br4923 RWGDGVPMADDKDAF--AEFVTAHRL-------
: