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VTDRQERAMSFGSIAEDYDGLRPQAPPEAVDWLMPPDCGVAVDVGAGTGLFTRALAGRAAHVIAVEPDAR MRAVLAHRSPAVRVLEGRGEAIPLPDRCADAVFVSSAWHWMDPQRAVPEIGRVLRDGGRFGLIWTSRDRD VDWVRDLDLLPGDDTSEADAPDRFRRRHENVVLPDPQIFHHVARETFTFVRTMTLDDAVAMLATYSRIIT ASPADRARRLAKARAVLTERFPGADAIDIPMQSRCWRADRIARAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2728 | - | - | 100% (255) | hypothetical protein MAV_2728 |
| M. avium 104 | MAV_4317 | - | 7e-44 | 39.27% (247) | putative methyltransferase |
| M. avium 104 | MAV_5229 | - | 8e-10 | 35.45% (110) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3374 | - | 3e-41 | 37.25% (247) | methyltransferase (methylase) |
| M. gilvum PYR-GCK | Mflv_4877 | - | 1e-36 | 38.10% (252) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3342 | - | 4e-41 | 37.25% (247) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_02584 | - | 3e-06 | 34.62% (104) | hypothetical protein MLBr_02584 |
| M. abscessus ATCC 19977 | MAB_3689 | - | 9e-43 | 42.79% (222) | putative methyltransferase |
| M. marinum M | MMAR_1183 | - | 8e-42 | 40.36% (223) | methyltransferase |
| M. smegmatis MC2 155 | MSMEG_1650 | - | 2e-42 | 39.27% (247) | methyltransferase type 11 |
| M. thermoresistible (build 8) | TH_1968 | - | 2e-40 | 38.02% (242) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | MUL_1436 | - | 5e-42 | 40.36% (223) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1552 | - | 7e-43 | 39.20% (250) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4877|M.gilvum_PYR-GCK ----------------MTAE---SDRRSLSFGAEAAA-YERGRPS--YPP
Mvan_1552|M.vanbaalenii_PYR-1 ----------------MTER---PDR-SLSFGAEAAA-YERGRPS--YPP
MSMEG_1650|M.smegmatis_MC2_155 ----------------MTPSDPLKQQRSLSFGSEAAA-YERGRPS--YPP
TH_1968|M.thermoresistible__bu ----------------------------LSFGAEAAA-YERGRPS--YPP
Mb3374|M.bovis_AF2122/97 ----------------MTCS---RRDMSLSFGSAVGA-YERGRPS--YPP
Rv3342|M.tuberculosis_H37Rv ----------------MTCS---RRDMSLSFGSAVGA-YERGRPS--YPP
MMAR_1183|M.marinum_M ----------------MSGS---AQDPSLSFGSAAAA-YERGRPS--YPP
MUL_1436|M.ulcerans_Agy99 ---------------MVSGS---AQDPSLSFGSAAAA-YERGRPS--YPP
MAB_3689|M.abscessus_ATCC_1997 ----------------MPDA---QAEPSLSFGSQAAA-YERGRPS--YPP
MAV_2728|M.avium_104 ----------------MTDR----QERAMSFGSIAED-YDGLRPQ--APP
MLBr_02584|M.leprae_Br4923 MDTRRRVWPVAIITPHVTDVFAQRATLTRSLQLLSEFRYEQPYPARFYRA
*: *: * .
Mflv_4877|M.gilvum_PYR-GCK EAID--------WLLADSGSRR-LEVLDLGAGTGKLTTRLVERGLDVVAV
Mvan_1552|M.vanbaalenii_PYR-1 EAID--------WLLPEHAH----DVLDLGAGTGKLTTRLAERGLAVVAV
MSMEG_1650|M.smegmatis_MC2_155 EAID--------WLLPDGAH----DVLDLGAGTGKLTTRLVERGLNVIAV
TH_1968|M.thermoresistible__bu EAID--------WLLPSDAR----DVLDLGAGTGKLTTRLVERGLNVTAV
Mb3374|M.bovis_AF2122/97 EAID--------WLLPAAAR----RVLDLGAGTGKLTTRLVERGLDVVAV
Rv3342|M.tuberculosis_H37Rv EAID--------WLLPAAAR----RVLDLGAGTGKLTTRLVERGLDVVAV
MMAR_1183|M.marinum_M EAID--------WLLPAGAR----DVLDLGAGTGKLTTRLVERGLDVVAV
MUL_1436|M.ulcerans_Agy99 EAID--------WLLPAGAR----DVLDLGAGTGKLTTRLVERGLDVVAV
MAB_3689|M.abscessus_ATCC_1997 EAID--------WLLPPGAH----DVLDLGAGTGKLTTRLVERGLNVVAV
MAV_2728|M.avium_104 EAVD--------WLMPPDCG----VAVDVGAGTGLFTRALAGRAAHVIAV
MLBr_02584|M.leprae_Br4923 LAADTVAMVGDLWLSTHGAPPVGRILLDVGSGSGYFAAAFADAGVRYIGV
* * ** . :*:*:*:* :: :. . .*
Mflv_4877|M.gilvum_PYR-GCK DPIP-EMLDLLRTSLPDTPALL-GTAEEIPLPDDSVDAVLVAQAWHWFDE
Mvan_1552|M.vanbaalenii_PYR-1 DPIP-EMLELLSTSLPDTPALL-GTAEEIPLPDDSVDAVLVAQAWHWFDP
MSMEG_1650|M.smegmatis_MC2_155 DPLA-EMLELLSNSLPDTPALL-GTAEEIPLPDNSVDAVLVAQAWHWFDP
TH_1968|M.thermoresistible__bu DPIP-EMLELLSKSLPDTPALL-GTAEEIPLPDNSVDAVLVAQAWHWFDV
Mb3374|M.bovis_AF2122/97 DPIP-EMLDVLRAALPQTVALL-GTAEEIPLDDNSVDAVLVAQAWHWVDP
Rv3342|M.tuberculosis_H37Rv DPIP-EMLDVLRAALPQTVALL-GTAEEIPLDDNSVDAVLVAQAWHWVDP
MMAR_1183|M.marinum_M DPIP-EMLEVLRASLPRTLALL-GTAEEIPLEDNSVDAVLVAQAWHWVDP
MUL_1436|M.ulcerans_Agy99 DPIP-EMLEVLRASLPRTLALL-GTAEEIPLEDNSVDAVLVAQAWHWVDP
MAB_3689|M.abscessus_ATCC_1997 DPLA-EMLEVLSNSLPDTPALL-GTAEEIPLPDNSVDAVLVAQAWHWVDP
MAV_2728|M.avium_104 EPDA-RMRAVLAHRSPAVRVLE-GRGEAIPLPDRCADAVFVSSAWHWMDP
MLBr_02584|M.leprae_Br4923 EPDPREMHAAGPALVPKAGAFVRASGMALPFADDAVDICLSSNVAEHVPQ
:* . .* * . .: . . :*: * ..* : :.. . .
Mflv_4877|M.gilvum_PYR-GCK TRAVK-EIARVLRPGGSLGLVWNNRDERLG-WVKDLGDIIGHEG------
Mvan_1552|M.vanbaalenii_PYR-1 ERAVK-EVARVLRPGGRLGLVWNNRDERLG-WVKDLGEIIGHEV------
MSMEG_1650|M.smegmatis_MC2_155 ELAVK-EVSRVLRPGGRLGLVWNVRDERLG-WVKDLGNIIGHE-------
TH_1968|M.thermoresistible__bu DRAVR-EVARVLRPGGRLGLVWNTRDERMG-WVKELGRIIGDEH------
Mb3374|M.bovis_AF2122/97 ARAIP-EVARVLRPGGRLGLVWNTRDERLG-WVRELGEIIGRDG------
Rv3342|M.tuberculosis_H37Rv ARAIP-EVARVLRPGGRLGLVWNTRDERLG-WVRELGEIIGRDG------
MMAR_1183|M.marinum_M ARAIP-EVARVLRPGGRLGLVWNTRDERLG-WVRELGRIIGRDS------
MUL_1436|M.ulcerans_Agy99 ARAIP-EVARVLRPGGRLGLVWNTRDERLG-WVRELGRIIGRDS------
MAB_3689|M.abscessus_ATCC_1997 ERAIP-EVARVLRPGGRLGLVWNVRDERLG-WVSDLGHIIGHEN------
MAV_2728|M.avium_104 QRAVP-EIGRVLRDGGRFGLIWTSRDRDVD-WVRDLDLLPGDDTSEADAP
MLBr_02584|M.leprae_Br4923 PWQLGNEMLRVTKPGGLVVLSYTIWLGPFGGHEMGLTHYLGGAR------
: *: ** : ** . * :. .. * *
Mflv_4877|M.gilvum_PYR-GCK DPWSQSV---ELPAP--FTGVERHHVEWTSYLTPQALIDLVASRSYCITS
Mvan_1552|M.vanbaalenii_PYR-1 DPFAQTV---ELPGP--FTDVEHHRVEWTSYLTPQALIDLVASRSYCITS
MSMEG_1650|M.smegmatis_MC2_155 DPFAHEV---TLPAP--FTDLERHHVEWTSYLTPQALIDLVASRSYCITS
TH_1968|M.thermoresistible__bu DPLSKTV---TLPEP--FTDVQRHQVEWTNYLTPQALIDLVASRSYCITS
Mb3374|M.bovis_AF2122/97 DPVRDRV---TLPEP--FTTVQRHQVEWTNYLTPQALIDLVASRSYCITS
Rv3342|M.tuberculosis_H37Rv DPVRDRV---TLPEP--FTTVQRHQVEWTNYLTPQALIDLVASRSYCITS
MMAR_1183|M.marinum_M DPVRDKV---TLPEP--FTGVARHHVEWTNYLTPQALIDLVASRSYCITS
MUL_1436|M.ulcerans_Agy99 DPVRDKV---TLPEP--FTGVARHHVEWTNYLTPQALIDLVASRSYCITS
MAB_3689|M.abscessus_ATCC_1997 AADSADVG--ALPAP--FTGQERHQVEWTNYLTPQALLDMVASRSYCITA
MAV_2728|M.avium_104 DRFRRRHENVVLPDPQIFHHVARETFTFVRTMTLDDAVAMLATYSRIITA
MLBr_02584|M.leprae_Br4923 AATRYVR-----------KHGHRAKNDYGSSLFPVSAADGLN-WAASTGV
: : : : :
Mflv_4877|M.gilvum_PYR-GCK PERVRARTLDRVRELLTTHPALANSSGLALPYVTVCVRATLA----
Mvan_1552|M.vanbaalenii_PYR-1 PEQVRARTLDRVRELLATHPALASSSGLALPYVTVCTRATLS----
MSMEG_1650|M.smegmatis_MC2_155 PEQVRTRTLGQVRELLSTHPALANSNGLALPYVTVCMRATLA----
TH_1968|M.thermoresistible__bu PAKVRARTLERVRELLATHPALANNSGLALPYITVCIRATLA----
Mb3374|M.bovis_AF2122/97 PAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRATLA----
Rv3342|M.tuberculosis_H37Rv PAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRATLA----
MMAR_1183|M.marinum_M PAEVRTKTLDQVRELLATHPALANSAGLALPYVTVCVSATLAA---
MUL_1436|M.ulcerans_Agy99 PAEVRTKTLDQVRELLATHPALANSAGLALPYVTVCVSATLAA---
MAB_3689|M.abscessus_ATCC_1997 PEAARKKTLQQVRELLATHPALAQSAGLALPYVTVSIRATLNR---
MAV_2728|M.avium_104 SPADRARRLAKARAVLTER--FPGADAIDIPMQSRCWRADRIARAG
MLBr_02584|M.leprae_Br4923 AVAAFPRYHPRWAWWLTSVPVLREFVVSNLVLVLRPR---------
. : : *: : :