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MPDAQAEPSLSFGSQAAAYERGRPSYPPEAIDWLLPPGAHDVLDLGAGTGKLTTRLVERGLNVVAVDPLA EMLEVLSNSLPDTPALLGTAEEIPLPDNSVDAVLVAQAWHWVDPERAIPEVARVLRPGGRLGLVWNVRDE RLGWVSDLGHIIGHENAADSADVGALPAPFTGQERHQVEWTNYLTPQALLDMVASRSYCITAPEAARKKT LQQVRELLATHPALAQSAGLALPYVTVSIRATLNR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3689 | - | - | 100% (245) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_1972c | - | 5e-22 | 33.79% (219) | hypothetical protein MAB_1972c |
| M. abscessus ATCC 19977 | MAB_1294c | - | 5e-10 | 33.33% (102) | hypothetical protein MAB_1294c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3374 | - | 1e-102 | 76.67% (240) | methyltransferase (methylase) |
| M. gilvum PYR-GCK | Mflv_4877 | - | 1e-102 | 77.31% (238) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3342 | - | 1e-102 | 76.67% (240) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_02273 | ubiE | 4e-07 | 36.26% (91) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. marinum M | MMAR_1183 | - | 1e-107 | 81.43% (237) | methyltransferase |
| M. avium 104 | MAV_4317 | - | 1e-103 | 79.15% (235) | putative methyltransferase |
| M. smegmatis MC2 155 | MSMEG_1650 | - | 1e-112 | 84.26% (235) | methyltransferase type 11 |
| M. thermoresistible (build 8) | TH_1968 | - | 1e-106 | 79.49% (234) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | MUL_1436 | - | 1e-107 | 81.43% (237) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1552 | - | 1e-107 | 80.51% (236) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3374|M.bovis_AF2122/97 ----------MTCS---RRDMSLSFGSAVGAYER-------GRPSYPPEA
Rv3342|M.tuberculosis_H37Rv ----------MTCS---RRDMSLSFGSAVGAYER-------GRPSYPPEA
MMAR_1183|M.marinum_M ----------MSGS---AQDPSLSFGSAAAAYER-------GRPSYPPEA
MUL_1436|M.ulcerans_Agy99 ---------MVSGS---AQDPSLSFGSAAAAYER-------GRPSYPPEA
MAV_4317|M.avium_104 ----------MTRS---RHDRSLSFGSAAAAYER-------GRPSYPPEA
Mflv_4877|M.gilvum_PYR-GCK ----------MTAE---SDRRSLSFGAEAAAYER-------GRPSYPPEA
Mvan_1552|M.vanbaalenii_PYR-1 ----------MTER---PDR-SLSFGAEAAAYER-------GRPSYPPEA
MSMEG_1650|M.smegmatis_MC2_155 ----------MTPSDPLKQQRSLSFGSEAAAYER-------GRPSYPPEA
TH_1968|M.thermoresistible__bu ----------------------LSFGAEAAAYER-------GRPSYPPEA
MAB_3689|M.abscessus_ATCC_1997 ----------MPDA---QAEPSLSFGSQAAAYER-------GRPSYPPEA
MLBr_02273|M.leprae_Br4923 MPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYDLTNTVLSLGQDRYWRRA
*. . *: *: * .*
Mb3374|M.bovis_AF2122/97 IDWLLPAAAR---RVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLR
Rv3342|M.tuberculosis_H37Rv IDWLLPAAAR---RVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLR
MMAR_1183|M.marinum_M IDWLLPAGAR---DVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLEVLR
MUL_1436|M.ulcerans_Agy99 IDWLLPAGAR---DVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLEVLR
MAV_4317|M.avium_104 IDWLLPVGAR---QVLDLGAGTGKLTTRLVERGLDVVAVDPIPDMLEVLR
Mflv_4877|M.gilvum_PYR-GCK IDWLLADSGSRRLEVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDLLR
Mvan_1552|M.vanbaalenii_PYR-1 IDWLLPEHAH---DVLDLGAGTGKLTTRLAERGLAVVAVDPIPEMLELLS
MSMEG_1650|M.smegmatis_MC2_155 IDWLLPDGAH---DVLDLGAGTGKLTTRLVERGLNVIAVDPLAEMLELLS
TH_1968|M.thermoresistible__bu IDWLLPSDAR---DVLDLGAGTGKLTTRLVERGLNVTAVDPIPEMLELLS
MAB_3689|M.abscessus_ATCC_1997 IDWLLPPGAH---DVLDLGAGTGKLTTRLVERGLNVVAVDPLAEMLEVLS
MLBr_02273|M.leprae_Br4923 TRSALRIGPGQ--KVLDLAAGTAVSTAELSKSGAWCVAADFSVRMLATG-
* ****.***. *:.* : * *.* **
Mb3374|M.bovis_AF2122/97 AALPQTVALLGTAEEIPLDDNSVDAVLVAQAWH-WVDPARAIPEVARVLR
Rv3342|M.tuberculosis_H37Rv AALPQTVALLGTAEEIPLDDNSVDAVLVAQAWH-WVDPARAIPEVARVLR
MMAR_1183|M.marinum_M ASLPRTLALLGTAEEIPLEDNSVDAVLVAQAWH-WVDPARAIPEVARVLR
MUL_1436|M.ulcerans_Agy99 ASLPRTLALLGTAEEIPLEDNSVDAVLVAQAWH-WVDPARAIPEVARVLR
MAV_4317|M.avium_104 SSLPETRALLGTAEEIPLEDNSVDVVLVAQAWH-WVDPERAIPEVARVLR
Mflv_4877|M.gilvum_PYR-GCK TSLPDTPALLGTAEEIPLPDDSVDAVLVAQAWH-WFDETRAVKEIARVLR
Mvan_1552|M.vanbaalenii_PYR-1 TSLPDTPALLGTAEEIPLPDDSVDAVLVAQAWH-WFDPERAVKEVARVLR
MSMEG_1650|M.smegmatis_MC2_155 NSLPDTPALLGTAEEIPLPDNSVDAVLVAQAWH-WFDPELAVKEVSRVLR
TH_1968|M.thermoresistible__bu KSLPDTPALLGTAEEIPLPDNSVDAVLVAQAWH-WFDVDRAVREVARVLR
MAB_3689|M.abscessus_ATCC_1997 NSLPDTPALLGTAEEIPLPDNSVDAVLVAQAWH-WVDPERAIPEVARVLR
MLBr_02273|M.leprae_Br4923 -GARKVPKVAADATQLPFSDGVFDAVTISFGLRNIADYQAALREMARVTR
. . : . * ::*: *. .*.* :: . : * *: *::** *
Mb3374|M.bovis_AF2122/97 PGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRV-TLPEPFTTVQRH
Rv3342|M.tuberculosis_H37Rv PGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRV-TLPEPFTTVQRH
MMAR_1183|M.marinum_M PGGRLGLVWNTRDERLGWVRELGRIIGRDSDPVRDKV-TLPEPFTGVARH
MUL_1436|M.ulcerans_Agy99 PGGRLGLVWNTRDERLGWVRELGRIIGRDSDPVRDKV-TLPEPFTGVARH
MAV_4317|M.avium_104 PGGRLGLVWNTRDERLGWVRELGRIIGSDGD-GRTHV-ALPEPFTDLAHH
Mflv_4877|M.gilvum_PYR-GCK PGGSLGLVWNNRDERLGWVKDLGDIIGHEGDPWSQSV-ELPAPFTGVERH
Mvan_1552|M.vanbaalenii_PYR-1 PGGRLGLVWNNRDERLGWVKDLGEIIGHEVDPFAQTV-ELPGPFTDVEHH
MSMEG_1650|M.smegmatis_MC2_155 PGGRLGLVWNVRDERLGWVKDLGNIIGHE-DPFAHEV-TLPAPFTDLERH
TH_1968|M.thermoresistible__bu PGGRLGLVWNTRDERMGWVKELGRIIGDEHDPLSKTV-TLPEPFTDVQRH
MAB_3689|M.abscessus_ATCC_1997 PGGRLGLVWNVRDERLGWVSDLGHIIGHENAADSADVGALPAPFTGQERH
MLBr_02273|M.leprae_Br4923 PGGQLVVCEFSTPTNALVANVYTEYLMRALPQVARLVSSNPDAYIYLAES
*** * : . . : * * .: .
Mb3374|M.bovis_AF2122/97 QVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALAN
Rv3342|M.tuberculosis_H37Rv QVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALAN
MMAR_1183|M.marinum_M HVEWTNYLTPQALIDLVASRSYCITSPAEVRTKTLDQVRELLATHPALAN
MUL_1436|M.ulcerans_Agy99 HVEWTNYLTPQALIDLVASRSYCITSPAEVRTKTLDQVRELLATHPALAN
MAV_4317|M.avium_104 EVEWTNYLTPQALIDLVASRSYCITSPTEVRTRTLDQVRHLLATHPALAN
Mflv_4877|M.gilvum_PYR-GCK HVEWTSYLTPQALIDLVASRSYCITSPERVRARTLDRVRELLTTHPALAN
Mvan_1552|M.vanbaalenii_PYR-1 RVEWTSYLTPQALIDLVASRSYCITSPEQVRARTLDRVRELLATHPALAS
MSMEG_1650|M.smegmatis_MC2_155 HVEWTSYLTPQALIDLVASRSYCITSPEQVRTRTLGQVRELLSTHPALAN
TH_1968|M.thermoresistible__bu QVEWTNYLTPQALIDLVASRSYCITSPAKVRARTLERVRELLATHPALAN
MAB_3689|M.abscessus_ATCC_1997 QVEWTNYLTPQALLDMVASRSYCITAPEAARKKTLQQVRELLATHPALAQ
MLBr_02273|M.leprae_Br4923 IRAWPDQVTLACQLSRTG-----WASP---------RWRNLTGGIVALHA
*.. :* . :. .. ::* : *.* **
Mb3374|M.bovis_AF2122/97 SNGLALPYVTVCVRATLA-
Rv3342|M.tuberculosis_H37Rv SNGLALPYVTVCVRATLA-
MMAR_1183|M.marinum_M SAGLALPYVTVCVSATLAA
MUL_1436|M.ulcerans_Agy99 SAGLALPYVTVCVSATLAA
MAV_4317|M.avium_104 STGLALPYVTRCTRATLAG
Mflv_4877|M.gilvum_PYR-GCK SSGLALPYVTVCVRATLA-
Mvan_1552|M.vanbaalenii_PYR-1 SSGLALPYVTVCTRATLS-
MSMEG_1650|M.smegmatis_MC2_155 SNGLALPYVTVCMRATLA-
TH_1968|M.thermoresistible__bu NSGLALPYITVCIRATLA-
MAB_3689|M.abscessus_ATCC_1997 SAGLALPYVTVSIRATLNR
MLBr_02273|M.leprae_Br4923 ADKPVR-------------
.