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VVMTNPRATNEDLTAKARIRNAALDLYAQYGEDRISLRDIASAAGVTLGLVQHHFKTKAGVRDAVDQLVV DYFAHALAQVPAEGSARHVAAARDEAVARMLRDNPPVVNYVRRAVLDPSEDRLHLLDALIELTRREITAL RGSGVASTKRPESTQILGVLIRQMGELLLQPMVDAVWDRVAKPTDARKPRLRITVEN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2705 | - | - | 100% (197) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4046 | - | 1e-11 | 35.20% (125) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_3130 | - | 9e-11 | 26.09% (138) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1251c | - | 1e-09 | 50.00% (60) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2369 | - | 1e-15 | 40.17% (117) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1219c | - | 1e-09 | 50.00% (60) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1861c | - | 2e-70 | 68.91% (193) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2297 | - | 6e-15 | 29.52% (166) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5074 | - | 1e-09 | 35.45% (110) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0547 | - | 3e-10 | 30.19% (159) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1500 | - | 3e-15 | 29.70% (165) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4277 | - | 1e-13 | 37.50% (112) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1251c|M.bovis_AF2122/97 ------MR-SADLTAHARIREAAIEQFGRHG-FGVGLRAIAEAAGVSAAL
Rv1219c|M.tuberculosis_H37Rv ------MR-SADLTAHARIREAAIEQFGRHG-FGVGLRAIAEAAGVSAAL
MSMEG_5074|M.smegmatis_MC2_155 ---------MDDRTAMARIRDTAIEQFGQHG-FNVGLRSIAEAAGVSAAL
TH_0547|M.thermoresistible__bu ------MRSADDRTAAARIRDAAIDQFGRHG-FDVSVRAIAEAAGVSPAL
MMAR_2297|M.marinum_M -----MHLASDDRTARARIRDEALRLFAERGPDAVTMRDIATAAGVSPAL
MUL_1500|M.ulcerans_Agy99 -----MHLATDDRTARARIRDEALRLFAERGPDAVTMRDIATAAGVSPAL
MAV_2705|M.avium_104 MVMTNPRATNEDLTAKARIRNAALDLYAQYGEDRISLRDIASAAGVTLGL
MAB_1861c|M.abscessus_ATCC_199 --MANPRASDEDLTAKARIRNTALDLYAQYGEERISLRAVASEAGVTLGL
Mflv_2369|M.gilvum_PYR-GCK MS---GRIGSEGPRNIERIRAAALHSFGEHGAAATTLRGVAAAAGVSLGL
Mvan_4277|M.vanbaalenii_PYR-1 MVSDVGRTGAEEPRNIERIRAAALRSLAANGAAATTMRGVAAAAGVSLGL
*** *: . * :* :* ***: .*
Mb1251c|M.bovis_AF2122/97 VIHHFGSKEGLRKACDDFVAEEIRSSKAAALKSNDPT---------TWLA
Rv1219c|M.tuberculosis_H37Rv VIHHFGSKEGLRKACDDFVAEEIRSSKAAALKSNDPT---------TWLA
MSMEG_5074|M.smegmatis_MC2_155 VIHHFGSKEGLRKACDDHVAEVILELKTESMHASDPA---------TWLA
TH_0547|M.thermoresistible__bu VIHHFGSKDNLRKACDDHIAEEIRSGKSAAIRSNDPA---------TWFA
MMAR_2297|M.marinum_M LIRHYGSKDGLVEAVDNHVIAIFEVLLTEATRETEAVGLSQAAVGGLLDG
MUL_1500|M.ulcerans_Agy99 LIRHYGSKDGLIEAVDNHVIAIFEVLLTEATRETEAVGLGQAAVGGLLDG
MAV_2705|M.avium_104 VQHHFKTKAGVRDAVDQLVVDYFAHALAQVPAEGSARHV----AAARDEA
MAB_1861c|M.abscessus_ATCC_199 VQHHFKTKAGLREAVDQLVVDYFVEALRSVDAEKDPRKL----VAARDAA
Mflv_2369|M.gilvum_PYR-GCK VQHHFATKAGLIEAVDDYVMKLVVTTMSRPLPE-PPVDS----VAEIGNR
Mvan_4277|M.vanbaalenii_PYR-1 VQHHFATKAGLINDVDEYVLRLITTTMSRPLAD-PPVDS----VVEIGDR
: :*: :* .: . *: : . .
Mb1251c|M.bovis_AF2122/97 QMAEIESYAPLMAYLVRSMQSGGELAKMLWQKMIDNAEEYLDEGVRAGTV
Rv1219c|M.tuberculosis_H37Rv QMAEIESYAPLMAYLVRSMQSGGELAKMLWQKMIDNAEEYLDEGVRAGTV
MSMEG_5074|M.smegmatis_MC2_155 YVAEIESYAPLMAYLVRSMQSGSELAKKFWRRMVDNAEQYLEEGVRTGML
TH_0547|M.thermoresistible__bu QIAELESYAPIMAYLVRSMQSGSDLAKMLWQKMIDDTRWYLDEGERAGTV
MMAR_2297|M.marinum_M LAAHLPPDSAVPAYLSRMLITGGTAGPGLFARLFRLSQDTLNAMVAAGTA
MUL_1500|M.ulcerans_Agy99 LATHLPPDSAVPAYLSRMLISGGTAGPGLFARLFRLSQDTLNAMAAAGTA
MAV_2705|M.avium_104 VARMLRDNPPVVNYVRRAVLDPSEDRLHLLDALIELTRREITALRGSGVA
MAB_1861c|M.abscessus_ATCC_199 VTSMLKANPPIVNYVRRAVLEPSDEQMHLLDALIGLTRDEVAMLRDEGMA
Mflv_2369|M.gilvum_PYR-GCK ITRMFAEEPDVVAYLGRALADGSPIGTRIFDTLLASGIARWQQRIDRGEV
Mvan_4277|M.vanbaalenii_PYR-1 VTTLFSEHPDVATYLGRALVDGSPAGVRIFDTLFAVGVARWQQRLDRGEL
: . : *: * : . : :. *
Mb1251c|M.bovis_AF2122/97 KPSRDPRARARFLAITGGGGFLLYLQMHENPTDLRAALRDYAHDMVLPSL
Rv1219c|M.tuberculosis_H37Rv KPSRDPRARARFLAITGGGGFLLYLQMHENPTDLRAALRDYAHDMVLPSL
MSMEG_5074|M.smegmatis_MC2_155 KPSRDPRARARFLAICGGGGFLLYLQMHDNPTDLRAVLRDYGEDMMLPAL
TH_0547|M.thermoresistible__bu KPSRDPKARARFLAISGGGSFLLYLQLHDNPTDLAAVLRDYSRDMMLPAL
MMAR_2297|M.marinum_M SPGADPAVRAAFLLVNDLAVLTLRPRLIEVLG-VDPLTDAGMRRWAGEVF
MUL_1500|M.ulcerans_Agy99 SPGADPAVRAAFLLVNDLAVLTLRPRLIEVLG-VDPLTDAGMRRWAGEVF
MAV_2705|M.avium_104 STKRPESTQILGVLIRQMGELLLQPMVDAVWDR--------VAKPTDARK
MAB_1861c|M.abscessus_ATCC_199 PTDRTASTQVVSVLVRQMGALLLQPLIDAAWDR--------VQS-GDAPK
Mflv_2369|M.gilvum_PYR-GCK RPDIDITWAAINGLVLALGAISLRHHLDRHLSEPFTTPRQ-LDRWQRAVD
Mvan_4277|M.vanbaalenii_PYR-1 RPDVDITWAAINGLVLALGAISLRSHLDRHLAEPLISPGQ-LARWQKAVD
. : . : * :
Mb1251c|M.bovis_AF2122/97 EVYTEGLLADRAMYEAFLAEAQQGEAHVG----------
Rv1219c|M.tuberculosis_H37Rv EVYTEGLLADRAMYEAFLAEAQQGEAHVG----------
MSMEG_5074|M.smegmatis_MC2_155 EIYSHGLMADTTMYETFLHQREAGVPFTGTSEEAT----
TH_0547|M.thermoresistible__bu EIYTHGLMADSTMFDAFVARETQQLSDQGGAHDDDVAAV
MMAR_2297|M.marinum_M AVYRDGLVSD-----------------------------
MUL_1500|M.ulcerans_Agy99 AVYRDGLVSD-----------------------------
MAV_2705|M.avium_104 PRLRITVEN------------------------------
MAB_1861c|M.abscessus_ATCC_199 PTLSIKVLD------------------------------
Mflv_2369|M.gilvum_PYR-GCK TLLREGLFRRE----------------------------
Mvan_4277|M.vanbaalenii_PYR-1 ALLREGLFRRPVSE-------------------------
: