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M. thermoresistible (build 8) TH_0547 ()

annotation: PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
coordinates: 1167362 - 1168033
length: 224

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0547-100% (224)PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. thermoresistible (build 8)TH_3536-7e-0635.90% (78) PUTATIVE transcriptional regulator, TetR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1251c-8e-8973.61% (216) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_2198-3e-7865.14% (218) TetR family transcriptional regulator
M. tuberculosis H37RvRv1219c-8e-8973.61% (216) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1360c-1e-6154.29% (210) TetR family transcriptional regulator
M. marinum MMMAR_4219-6e-8573.43% (207) transcriptional regulator
M. avium 104MAV_1363-4e-8770.83% (216) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_5074-3e-8371.72% (198) transcriptional regulatory protein
M. ulcerans Agy99MUL_1500-2e-1837.74% (159) transcriptional regulator
M. vanbaalenii PYR-1Mvan_4498-1e-9072.73% (220) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2198|M.gilvum_PYR-GCK          ---MRSVDDLTAAARIRDAAVELFGAEGF-AVSVRTIAAAAGVSPGLVIH
Mvan_4498|M.vanbaalenii_PYR-1       ---MRSADDLTAAARIRDAAIDLFGRDGF-AVGVRSIASAAGVSPGLVIH
Mb1251c|M.bovis_AF2122/97           ---MR-SADLTAHARIREAAIEQFGRHGF-GVGLRAIAEAAGVSAALVIH
Rv1219c|M.tuberculosis_H37Rv        ---MR-SADLTAHARIREAAIEQFGRHGF-GVGLRAIAEAAGVSAALVIH
MMAR_4219|M.marinum_M               ---MR-SVDLTAAARIRDAAIEQFGQHGF-GVSLRAIAEGAGVSAALVIH
MAV_1363|M.avium_104                MLNMR-SADLTAAARIRDAAIEQFGEHGF-GVGLRRIAEAAGVSAALVIH
MSMEG_5074|M.smegmatis_MC2_155      ------MDDRTAMARIRDTAIEQFGQHGF-NVGLRSIAEAAGVSAALVIH
TH_0547|M.thermoresistible__bu      ---MRSADDRTAAARIRDAAIDQFGRHGF-DVSVRAIAEAAGVSPALVIH
MAB_1360c|M.abscessus_ATCC_199      ---MRSADDLTAAARIRDAAIKLWGEQGN-GASVRAIADAAGVSPALVIH
MUL_1500|M.ulcerans_Agy99           --MHLATDDRTARARIRDEALRLFAERGPDAVTMRDIATAAGVSPALLIR
                                            * ** ****: *:  :.  *   . :* ** .****..*:*:

Mflv_2198|M.gilvum_PYR-GCK          HFGSKDQLHKACDAYVAETVRAAKSESIQTSDPA---------TWLAQMA
Mvan_4498|M.vanbaalenii_PYR-1       HFGSKDGLRKACDDFVAETVRASKSEAIQSSDPA---------TWLAQIA
Mb1251c|M.bovis_AF2122/97           HFGSKEGLRKACDDFVAEEIRSSKAAALKSNDPT---------TWLAQMA
Rv1219c|M.tuberculosis_H37Rv        HFGSKEGLRKACDDFVAEEIRSSKAAALKSNDPT---------TWLAQMA
MMAR_4219|M.marinum_M               HFGSKEGLRKACDNYVAEEIRSEKLTAMQSNDPA---------TWLGQLA
MAV_1363|M.avium_104                HFGSKEGLRKACDDHIAEQIRESKTEALQTNDPA---------VWFGQLA
MSMEG_5074|M.smegmatis_MC2_155      HFGSKEGLRKACDDHVAEVILELKTESMHASDPA---------TWLAYVA
TH_0547|M.thermoresistible__bu      HFGSKDNLRKACDDHIAEEIRSGKSAAIRSNDPA---------TWFAQIA
MAB_1360c|M.abscessus_ATCC_199      HYGSKDGLRQAVDDYLLAYIRSEKSRTITSNDPQ---------VWLDAID
MUL_1500|M.ulcerans_Agy99           HYGSKDGLIEAVDNHVIAIFEVLLTEATRETEAVGLGQAAVGGLLDGLAT
                                    *:***: * :* * .:   .      :   .:.                 

Mflv_2198|M.gilvum_PYR-GCK          EIEEYAPLMAYLVRSLQAGGELGKMLWRTMTNDVEQYLEDGVRAGTVKPS
Mvan_4498|M.vanbaalenii_PYR-1       EIEEYAPLMAYLVRTLQTGGELAKMLWQNMIDNAEQYIEEGVRAGTVKPS
Mb1251c|M.bovis_AF2122/97           EIESYAPLMAYLVRSMQSGGELAKMLWQKMIDNAEEYLDEGVRAGTVKPS
Rv1219c|M.tuberculosis_H37Rv        EIESYAPLMAYLVRSMQSGGELAKMLWQKMIDNAEEYLDEGVRAGTVKPS
MMAR_4219|M.marinum_M               QVESYAPLMAYLVRSMQSGGELAMMLWQQMIDNAEEYLAVGVRAGTIKAS
MAV_1363|M.avium_104                EIEEFAPLIAYVLRSMQTGGDLAKMLWRQMIENAEGYLEEGVRAGTIKPS
MSMEG_5074|M.smegmatis_MC2_155      EIESYAPLMAYLVRSMQSGSELAKKFWRRMVDNAEQYLEEGVRTGMLKPS
TH_0547|M.thermoresistible__bu      ELESYAPIMAYLVRSMQSGSDLAKMLWQKMIDDTRWYLDEGERAGTVKPS
MAB_1360c|M.abscessus_ATCC_199      EIETFAPMVRYLLHSVQSGGEPGRAFLRRSIDDAEQYLEDGVRAGTIKPS
MUL_1500|M.ulcerans_Agy99           HLPPDSAVPAYLSRMLISGGTAGPGLFARLFRLSQDTLNAMAAAGTASPG
                                    .:   :.:  *: : : :*.  .  :        .  :     :*  ...

Mflv_2198|M.gilvum_PYR-GCK          ADPRARAFFLSMASGGGFLLYLQLHES-TDIRVVLRDYSEAMVLPALELY
Mvan_4498|M.vanbaalenii_PYR-1       ADPRGRARFLAMAGGGGFLLYLQMHDNPTDLRAVLRDYSEEMVLPALELY
Mb1251c|M.bovis_AF2122/97           RDPRARARFLAITGGGGFLLYLQMHENPTDLRAALRDYAHDMVLPSLEVY
Rv1219c|M.tuberculosis_H37Rv        RDPRARARFLAITGGGGFLLYLQMHENPTDLRAALRDYAHDMVLPSLEVY
MMAR_4219|M.marinum_M               RDPKARAKFLAITGAGGFLLYLQMHQTPTDLRAVLRDYARDMLLPSLEIY
MAV_1363|M.avium_104                RDPRARAKYLGITGGGGLLLYLQMHDNPTDLRAVLRDYSRDMILPALEIY
MSMEG_5074|M.smegmatis_MC2_155      RDPRARARFLAICGGGGFLLYLQMHDNPTDLRAVLRDYGEDMMLPALEIY
TH_0547|M.thermoresistible__bu      RDPKARARFLAISGGGSFLLYLQLHDNPTDLAAVLRDYSRDMMLPALEIY
MAB_1360c|M.abscessus_ATCC_199      RDPKGRALWVSLNSVGSLIIYVQMHAN-EDLREILRRYADELIFPAIEVY
MUL_1500|M.ulcerans_Agy99           ADPAVRAAFLLVNDLAVLTLRPRLIEV-LGVDPLTDAGMRRWAGEVFAVY
                                     **  ** :: : . . : :  ::     .:               : :*

Mflv_2198|M.gilvum_PYR-GCK          THGLLTDSTMYDAFVAER-----AHDHSSPSTG-ARDA
Mvan_4498|M.vanbaalenii_PYR-1       TNGLMTDSTMYDAFVARR-----AQGIPFTSTEGAHDD
Mb1251c|M.bovis_AF2122/97           TEGLLADRAMYEAFLAEA-----QQGEAHVG-------
Rv1219c|M.tuberculosis_H37Rv        TEGLLADRAMYEAFLAEA-----QQGEAHVG-------
MMAR_4219|M.marinum_M               TEGLMADSTMYDAFLAQD-----NQGESHGH-------
MAV_1363|M.avium_104                TEGLMADRTMYDAFLAAE-----DQGDSHGN-------
MSMEG_5074|M.smegmatis_MC2_155      SHGLMADTTMYETFLHQR-----EAGVPFTGTSEEAT-
TH_0547|M.thermoresistible__bu      THGLMADSTMFDAFVARETQQLSDQGGAHDDDVAAV--
MAB_1360c|M.abscessus_ATCC_199      TEGLMTDSTMLDAFAVQQ-----DKSHSKGDPK-----
MUL_1500|M.ulcerans_Agy99           RDGLVSD-------------------------------
                                     .**::*