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VSDVGRTGAEEPRNIERIRAAALRSLAANGAAATTMRGVAAAAGVSLGLVQHHFATKAGLINDVDEYVLR LITTTMSRPLADPPVDSVVEIGDRVTTLFSEHPDVATYLGRALVDGSPAGVRIFDTLFAVGVARWQQRLD RGELRPDVDITWAAINGLVLALGAISLRSHLDRHLAEPLISPGQLARWQKAVDALLREGLFRRPVSE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4277 | - | - | 100% (208) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4498 | - | 4e-08 | 27.61% (134) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5714 | - | 3e-06 | 29.20% (113) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3439c | - | 1e-06 | 33.63% (113) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2369 | - | 1e-87 | 77.39% (199) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3405c | - | 1e-06 | 33.63% (113) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1861c | - | 6e-15 | 31.85% (157) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2297 | - | 7e-16 | 31.22% (189) | transcriptional regulator |
| M. avium 104 | MAV_3130 | - | 1e-38 | 46.82% (173) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6479 | - | 2e-06 | 28.32% (113) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_0084 | - | 2e-07 | 28.32% (113) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_1500 | - | 5e-16 | 31.22% (189) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4277|M.vanbaalenii_PYR-1 -----MVSDVGRTGAEEPRNIERIRAAALRSLAANGAAATTMRGVAAAAG
Mflv_2369|M.gilvum_PYR-GCK -----MS---GRIGSEGPRNIERIRAAALHSFGEHGAAATTLRGVAAAAG
MAV_3130|M.avium_104 ---------------------------------MRGIAATPLRAVAEAAD
Mb3439c|M.bovis_AF2122/97 -MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSK
Rv3405c|M.tuberculosis_H37Rv -MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSK
MMAR_2297|M.marinum_M ----------MHLASDDRTARARIRDEALRLFAERGPDAVTMRDIATAAG
MUL_1500|M.ulcerans_Agy99 ----------MHLATDDRTARARIRDEALRLFAERGPDAVTMRDIATAAG
MSMEG_6479|M.smegmatis_MC2_155 MSDPAMESTRRRLSARQADTVERLGRAAVELISREGYAGLTVRRVAAEAG
TH_0084|M.thermoresistible__bu VSDPALESTRRRLTAKQADTVDRLGRAAVELLQREGFAGLTIRRVAAEAG
MAB_1861c|M.abscessus_ATCC_199 -------MANPRASDEDLTAKARIRNTALDLYAQYGEERISLRAVASEAG
* .:* :* :
Mvan_4277|M.vanbaalenii_PYR-1 VSLGLVQHHFATKAGLINDVDEYVLRLITTTMS-RPLADPPVDSVVEIGD
Mflv_2369|M.gilvum_PYR-GCK VSLGLVQHHFATKAGLIEAVDDYVMKLVVTTMS-RPLPEPPVDSVAEIGN
MAV_3130|M.avium_104 VSIGLVQHHFRTKAALTAAVDQYVLQVLDEALKPTMLPEPPEDGLNEAGH
Mb3439c|M.bovis_AF2122/97 VNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGR
Rv3405c|M.tuberculosis_H37Rv VNHGLVFRHFGTKDQLVGAVLDHLGTKLTRLLHSEAPADIIERALDRHGR
MMAR_2297|M.marinum_M VSPALLIRHYGSKDGLVEAVDNHV-IAIFEVLLTEATRETEAVGLSQAAV
MUL_1500|M.ulcerans_Agy99 VSPALLIRHYGSKDGLIEAVDNHV-IAIFEVLLTEATRETEAVGLGQAAV
MSMEG_6479|M.smegmatis_MC2_155 VGSATAYTYFSSKEHLVAEVFWRRLSAAPPAVHESPDPATRVVEVLQ---
TH_0084|M.thermoresistible__bu VGAATAYTYFSSKEHLVAEVFWRRLAAAPPADHKSDDPATRVIEVLR---
MAB_1861c|M.abscessus_ATCC_199 VTLGLVQHHFKTKAGLREAVDQLVVDYFVEALRSVDAEKDPRKLVAARDA
* . :: :* * * :
Mvan_4277|M.vanbaalenii_PYR-1 R-----VTTLFSEHPDVATYLGRALVDGSPAGVRIFDTLFAVGVARWQQR
Mflv_2369|M.gilvum_PYR-GCK R-----ITRMFAEEPDVVAYLGRALADGSPIGTRIFDTLLASGIARWQQR
MAV_3130|M.avium_104 R-----LTTLMAERPDVVMYLGRALAEGGALGSVIFDGLLRICATQGEQF
Mb3439c|M.bovis_AF2122/97 -------------------VLARALLDGYPVG--QLQQRFPNVAELLDAV
Rv3405c|M.tuberculosis_H37Rv -------------------VLARALLDGYPVG--QLQQRFPNVAELLDAV
MMAR_2297|M.marinum_M GGLLDGLAAHLPPDSAVPAYLSRMLITGGTAGPGLFARLFRLSQDTLNAM
MUL_1500|M.ulcerans_Agy99 GGLLDGLATHLPPDSAVPAYLSRMLISGGTAGPGLFARLFRLSQDTLNAM
MSMEG_6479|M.smegmatis_MC2_155 -------------------HIASLVADEPAFAGAVTTALLGKDPD-----
TH_0084|M.thermoresistible__bu -------------------HIALLVADEPEFAGAVTTALLGRDPD-----
MAB_1861c|M.abscessus_ATCC_199 A-----VTSMLKANPPIVNYVRRAVLEPSDEQMHLLDALIGLTRDEVAML
: : :
Mvan_4277|M.vanbaalenii_PYR-1 LDRGELRPDVDITWAAINGLVLALGAISLRSHLDRHLAEPLISPGQLARW
Mflv_2369|M.gilvum_PYR-GCK IDRGEVRPDIDITWAAINGLVLALGAISLRHHLDRHLSEPFTTPRQLDRW
MAV_3130|M.avium_104 VAQGNTQLDLDPDWAAINILVLRVGAIILHPYIELHLGKPFFTEQQLRRW
Mb3439c|M.bovis_AF2122/97 RPRYDSDLGARLAVAHALALQ--FGWRLFAPMLRSATGIDELTGDELRLS
Rv3405c|M.tuberculosis_H37Rv RPRYDSDLGARLAVAHALALQ--FGWRLFAPMLRSATGIDELTGDELRLS
MMAR_2297|M.marinum_M VAAGTASPGADPAVRAAFLLVNDLAVLTLRPRLIEVLGVDPLTDAGMRRW
MUL_1500|M.ulcerans_Agy99 AAAGTASPGADPAVRAAFLLVNDLAVLTLRPRLIEVLGVDPLTDAGMRRW
MSMEG_6479|M.smegmatis_MC2_155 VDALRQRIGADIRQRLVAALGPDVRIDVIEALELLYTGTMVWAGMGYDSY
TH_0084|M.thermoresistible__bu VEVLRQRIGRDIRDRLLAALGPQTDYDVIEALELLYIGVLVWVGMGYSSQ
MAB_1861c|M.abscessus_ATCC_199 RDEGMAPTDRTASTQVVSVLVRQMGALLLQPLIDAAWDRVQSGDAPKPTL
. * :
Mvan_4277|M.vanbaalenii_PYR-1 QKAVDALLREGLFRRPVSE--------
Mflv_2369|M.gilvum_PYR-GCK QRAVDTLLREGLFRRE-----------
MAV_3130|M.avium_104 DASVTSLIRHGMFLEDTQHPYGDANAR
Mb3439c|M.bovis_AF2122/97 VNDAVARILEPH---------------
Rv3405c|M.tuberculosis_H37Rv VNDAVARILEPH---------------
MMAR_2297|M.marinum_M AGEVFAVYRDGLVSD------------
MUL_1500|M.ulcerans_Agy99 AGEVFAVYRDGLVSD------------
MSMEG_6479|M.smegmatis_MC2_155 EQVVRRLEKSARLVLS-----------
TH_0084|M.thermoresistible__bu EDMTRRLEKSARLILR-----------
MAB_1861c|M.abscessus_ATCC_199 SIKVLD---------------------
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