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ANPRASDEDLTAKARIRNTALDLYAQYGEERISLRAVASEAGVTLGLVQHHFKTKAGLREAVDQLVVDYF VEALRSVDAEKDPRKLVAARDAAVTSMLKANPPIVNYVRRAVLEPSDEQMHLLDALIGLTRDEVAMLRDE GMAPTDRTASTQVVSVLVRQMGALLLQPLIDAAWDRVQSGDAPKPTLSIKVLD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1861c | - | - | 100% (194) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1518 | - | 2e-12 | 28.75% (160) | hypothetical protein MAB_1518 |
| M. abscessus ATCC 19977 | MAB_1360c | - | 3e-11 | 36.45% (107) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1251c | - | 3e-10 | 30.60% (134) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2369 | - | 7e-17 | 35.85% (159) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1219c | - | 3e-10 | 30.60% (134) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2316 | - | 3e-14 | 29.59% (196) | transcriptional regulator |
| M. avium 104 | MAV_2705 | - | 2e-70 | 68.91% (193) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5074 | - | 4e-11 | 34.55% (110) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0547 | - | 3e-11 | 34.13% (126) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1500 | - | 3e-13 | 28.48% (165) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4277 | - | 7e-15 | 31.85% (157) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1251c|M.bovis_AF2122/97 ------MR-SADLTAHARIREAAIEQFGRHGFG-VGLRAIAEAAGVSAAL
Rv1219c|M.tuberculosis_H37Rv ------MR-SADLTAHARIREAAIEQFGRHGFG-VGLRAIAEAAGVSAAL
MSMEG_5074|M.smegmatis_MC2_155 ---------MDDRTAMARIRDTAIEQFGQHGFN-VGLRSIAEAAGVSAAL
TH_0547|M.thermoresistible__bu ------MRSADDRTAAARIRDAAIDQFGRHGFD-VSVRAIAEAAGVSPAL
MMAR_2316|M.marinum_M -------MCSADLTAKARIRNAAVARFARDGFQKVNLRAIATSAGVSEAL
MUL_1500|M.ulcerans_Agy99 -----MHLATDDRTARARIRDEALRLFAERGPDAVTMRDIATAAGVSPAL
MAB_1861c|M.abscessus_ATCC_199 --MANPRASDEDLTAKARIRNTALDLYAQYGEERISLRAVASEAGVTLGL
MAV_2705|M.avium_104 MVMTNPRATNEDLTAKARIRNAALDLYAQYGEDRISLRDIASAAGVTLGL
Mflv_2369|M.gilvum_PYR-GCK MS---GRIGSEGPRNIERIRAAALHSFGEHGAAATTLRGVAAAAGVSLGL
Mvan_4277|M.vanbaalenii_PYR-1 MVSDVGRTGAEEPRNIERIRAAALRSLAANGAAATTMRGVAAAAGVSLGL
*** *: . * :* :* ***: .*
Mb1251c|M.bovis_AF2122/97 VIHHFGSKEGLRKACDDFVAEEIRSSKAAALKSNDPT--------TWL-A
Rv1219c|M.tuberculosis_H37Rv VIHHFGSKEGLRKACDDFVAEEIRSSKAAALKSNDPT--------TWL-A
MSMEG_5074|M.smegmatis_MC2_155 VIHHFGSKEGLRKACDDHVAEVILELKTESMHASDPA--------TWL-A
TH_0547|M.thermoresistible__bu VIHHFGSKDNLRKACDDHIAEEIRSGKSAAIRSNDPA--------TWF-A
MMAR_2316|M.marinum_M IFHHFGSKDGLRAACDEYVLNVLVGRARTAGRPTAMA--------DLLGV
MUL_1500|M.ulcerans_Agy99 LIRHYGSKDGLIEAVDNHVIAIFEVLLTEATRETEAVGLGQAAVGGLLDG
MAB_1861c|M.abscessus_ATCC_199 VQHHFKTKAGLREAVDQLVVDYFVEALRSVDAEKDPRKL----VAARDAA
MAV_2705|M.avium_104 VQHHFKTKAGVRDAVDQLVVDYFAHALAQVPAEGSARHV----AAARDEA
Mflv_2369|M.gilvum_PYR-GCK VQHHFATKAGLIEAVDDYVMKLVVTTMSRPLPE-PPVDS----VAEIGNR
Mvan_4277|M.vanbaalenii_PYR-1 VQHHFATKAGLINDVDEYVLRLITTTMSRPLAD-PPVDS----VVEIGDR
: :*: :* .: *: : .
Mb1251c|M.bovis_AF2122/97 QMAEIESYAPLMAYLVRSMQSGGELAKMLWQKMIDNAEEYLDEGVRAGTV
Rv1219c|M.tuberculosis_H37Rv QMAEIESYAPLMAYLVRSMQSGGELAKMLWQKMIDNAEEYLDEGVRAGTV
MSMEG_5074|M.smegmatis_MC2_155 YVAEIESYAPLMAYLVRSMQSGSELAKKFWRRMVDNAEQYLEEGVRTGML
TH_0547|M.thermoresistible__bu QIAELESYAPIMAYLVRSMQSGSDLAKMLWQKMIDDTRWYLDEGERAGTV
MMAR_2316|M.marinum_M YLSNPEEYRLQVQYMARAIEDDAPAAGTFVDTMVEESEAIFRAGAADGSM
MUL_1500|M.ulcerans_Agy99 LATHLPPDSAVPAYLSRMLISGGTAGPGLFARLFRLSQDTLNAMAAAGTA
MAB_1861c|M.abscessus_ATCC_199 VTSMLKANPPIVNYVRRAVLEPSDEQMHLLDALIGLTRDEVAMLRDEGMA
MAV_2705|M.avium_104 VARMLRDNPPVVNYVRRAVLDPSEDRLHLLDALIELTRREITALRGSGVA
Mflv_2369|M.gilvum_PYR-GCK ITRMFAEEPDVVAYLGRALADGSPIGTRIFDTLLASGIARWQQRIDRGEV
Mvan_4277|M.vanbaalenii_PYR-1 VTTLFSEHPDVATYLGRALVDGSPAGVRIFDTLFAVGVARWQQRLDRGEL
*: * : . . : :. *
Mb1251c|M.bovis_AF2122/97 KPSRDPRARARFLAITGGGGFLLYLQMHENPTDLRAALRDYAHDMVLPSL
Rv1219c|M.tuberculosis_H37Rv KPSRDPRARARFLAITGGGGFLLYLQMHENPTDLRAALRDYAHDMVLPSL
MSMEG_5074|M.smegmatis_MC2_155 KPSRDPRARARFLAICGGGGFLLYLQMHDNPTDLRAVLRDYGEDMMLPAL
TH_0547|M.thermoresistible__bu KPSRDPKARARFLAISGGGSFLLYLQLHDNPTDLAAVLRDYSRDMMLPAL
MMAR_2316|M.marinum_M RPSSDPRALAVLNLLVALG-LLTMAPPMARALGHEHFGPEVLQRMAVPAL
MUL_1500|M.ulcerans_Agy99 SPGADPAVRAAFLLVNDLAVLTLRPRLIE-VLGVDPLTDAGMRRWAGEVF
MAB_1861c|M.abscessus_ATCC_199 PTDRTASTQVVSVLVRQMGALLLQP-LIDAAWDR-------VQS-GDAPK
MAV_2705|M.avium_104 STKRPESTQILGVLIRQMGELLLQP-MVDAVWDR-------VAKPTDARK
Mflv_2369|M.gilvum_PYR-GCK RPDIDITWAAINGLVLALGAISLRH-HLDRHLSEPFTTPRQLDRWQRAVD
Mvan_4277|M.vanbaalenii_PYR-1 RPDVDITWAAINGLVLALGAISLRS-HLDRHLAEPLISPGQLARWQKAVD
. : . :
Mb1251c|M.bovis_AF2122/97 EVYTEGLLADRAMYEAFLAEAQQGEAHVG----------
Rv1219c|M.tuberculosis_H37Rv EVYTEGLLADRAMYEAFLAEAQQGEAHVG----------
MSMEG_5074|M.smegmatis_MC2_155 EIYSHGLMADTTMYETFLHQREAGVPFTGTSEEAT----
TH_0547|M.thermoresistible__bu EIYTHGLMADSTMFDAFVARETQQLSDQGGAHDDDVAAV
MMAR_2316|M.marinum_M ELYTRGLYTDDTLAKAAQDAWVARRAPQQEG--------
MUL_1500|M.ulcerans_Agy99 AVYRDGLVSD-----------------------------
MAB_1861c|M.abscessus_ATCC_199 PTLSIKVLD------------------------------
MAV_2705|M.avium_104 PRLRITVEN------------------------------
Mflv_2369|M.gilvum_PYR-GCK TLLREGLFRRE----------------------------
Mvan_4277|M.vanbaalenii_PYR-1 ALLREGLFRRPVSE-------------------------
: