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MSELFPAYRASWETDAHRDLRKHAAEFLRKESTPNQERWSAQHQVDREFWNKMGDAGLLGLDLPEEYGGA GGDFGFSAVVGEELALAQDTSTGWAVHSPIVAHYINTYGNEEQRARWMPGIISGDLVLAIAMTEPGTGSD LQAVRTTAIPDGDHYVINGSKTFISNGTHCDLLVIVAKTDPSQGAAGVSLIVAETKDLPGFERGRVLEKV GQHGQDTRELFFTDMRVPIANRLGDKDGLGFYQLMEQLARERLIIAAVCSGMAEGALIEAIKYTKEREAF GKPLIKFQNTKFQLAELKAEVLSIKTTVDYCVQDYINGNNDPATASMAKLIAADKAVSVVDRCVQFFGGY GYMMEYPIARAYAAARVNKIYGGTSEIMKEIISRSL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1863 | - | - | 100% (386) | acyl-CoA dehydrogenase FadE |
| M. abscessus ATCC 19977 | MAB_2081 | - | e-115 | 55.20% (375) | acyl CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3040c | - | e-102 | 49.06% (371) | acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2743c | fadE20 | 1e-95 | 47.44% (371) | acyl-CoA dehydrogenase FADE20 |
| M. gilvum PYR-GCK | Mflv_4601 | - | 1e-111 | 53.16% (380) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv2724c | fadE20 | 8e-97 | 47.71% (371) | acyl-CoA dehydrogenase FADE20 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 3e-49 | 31.64% (373) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_3132 | - | 1e-116 | 55.73% (375) | acyl-CoA dehydrogenase |
| M. avium 104 | MAV_2703 | - | 1e-172 | 76.49% (387) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5197 | - | 4e-99 | 47.72% (373) | long-chain specific acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3180 | - | 1e-106 | 49.60% (375) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_3367 | fadE20 | 7e-96 | 46.63% (371) | acyl-CoA dehydrogenase FadE20 |
| M. vanbaalenii PYR-1 | Mvan_2439 | - | 1e-100 | 47.24% (381) | long-chain-acyl-CoA dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2743c|M.bovis_AF2122/97 MGS-----ATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVD
Rv2724c|M.tuberculosis_H37Rv MGS-----ATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVD
MUL_3367|M.ulcerans_Agy99 MGS-----AIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVD
Mvan_2439|M.vanbaalenii_PYR-1 MGASEAKPVIAYERTLFEPEHDMFRESFRAFLDRHVAPHHEEWEKNKLVD
MSMEG_5197|M.smegmatis_MC2_155 -----------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVD
MAB_1863|M.abscessus_ATCC_1997 ----MSELFPAYRASWETDAHRDLRKHAAEFLRKESTPNQERWSAQHQVD
MAV_2703|M.avium_104 ----MSELFPDYRPSWETDQHRELRKHAAEFFRKEATPNQERWAAQHAVD
Mflv_4601|M.gilvum_PYR-GCK --------MAANRSSWMDDDLDALRDLARTFCEKEVAPHSARFIEQHHVD
MMAR_3132|M.marinum_M --------MTASISPWMSAELLELRDLAAKFFSTELAPHAQRFADQHQVD
TH_3180|M.thermoresistible__bu -------MITKRMSPWFDDEVRALYDLAREFFEREVVAHVDTWDAQRHID
MLBr_00737|M.leprae_Br4923 --MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFP
: . . .
Mb2743c|M.bovis_AF2122/97 RGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFG
Rv2724c|M.tuberculosis_H37Rv RGVWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFG
MUL_3367|M.ulcerans_Agy99 RGVWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFG
Mvan_2439|M.vanbaalenii_PYR-1 RDVWLEAGKQGFLGMAVPEEYGGGGVDDFRYNTIVTEEVTAGRYTGLGFS
MSMEG_5197|M.smegmatis_MC2_155 RSAYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKSGVHGPALS
MAB_1863|M.abscessus_ATCC_1997 REFWNKMGDAGLLGLDLPEEYGGAG-GDFGFSAVVGEELALAQDTSTGWA
MAV_2703|M.avium_104 REFWNKAGDAGLLGLDLPEEYGGAG-GDFAMNVVVQEELAYAYDQGFGFA
Mflv_4601|M.gilvum_PYR-GCK RDLWTRAGDLGLLCMSIPEQYGGGG-GTFAHEAVLIEEQARIGDSAWGAP
MMAR_3132|M.marinum_M RELWHKAGELGLLCMSIPEEYGGGG-GTFAHEAVVLEEQARVGDSSWGAG
TH_3180|M.thermoresistible__bu RQVWLEAGKLGLLLCSVPEEYGGGG-GTFAHDVAVFDAQGYSGDLSLGIA
MLBr_00737|M.leprae_Br4923 EEALAALNASGFNAIHVPEEYGGQG-ADSVAACIVIEEVARVDASASLIP
. . *: :**::** * : : .
Mb2743c|M.bovis_AF2122/97 LHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGIT
Rv2724c|M.tuberculosis_H37Rv LHNDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGIT
MUL_3367|M.ulcerans_Agy99 LHNEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIK
Mvan_2439|M.vanbaalenii_PYR-1 LHNDVAAPYLIRLATEEQKQRWLPKFCSGEIISAIAMTEPGTGSDLQGIK
MSMEG_5197|M.smegmatis_MC2_155 LHNDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIR
MAB_1863|M.abscessus_ATCC_1997 VHSPIVAHYINTYGNEEQRARWMPGIISGDLVLAIAMTEPGTGSDLQAVR
MAV_2703|M.avium_104 VHSPIVAHYIWAYGSDEQRRRWLPKIISGEAVLAIAMTEPGTGSDLQSVK
Mflv_4601|M.gilvum_PYR-GCK LHSGIVAHYLLEYGTDEQKERFLPRLATGEMVGAIAMTEPGTGSDLQSVT
MMAR_3132|M.marinum_M LHSGIVAHYILQYAAEELRRQWLPKMASGEMIGAIAMTEPGTGSDLQSVK
TH_3180|M.thermoresistible__bu VHSGIVPHYIVKYGSEEQKRQWLPPMATGEVLSAIGMTEPGAGSDLKAIR
MLBr_00737|M.leprae_Br4923 AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
. : : . :* : : :* : : : .::* :*** .:
Mb2743c|M.bovis_AF2122/97 TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
Rv2724c|M.tuberculosis_H37Rv TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
MUL_3367|M.ulcerans_Agy99 TRAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVER
Mvan_2439|M.vanbaalenii_PYR-1 TRAVRDGDHYVLNGAKTFITNGIHSDLVIVVAQTDPDKGALGFSLLVVER
MSMEG_5197|M.smegmatis_MC2_155 TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
MAB_1863|M.abscessus_ATCC_1997 TTAIPDGDHYVINGSKTFISNGTHCDLLVIVAKTDPSQGAAGVSLIVAET
MAV_2703|M.avium_104 TTARRDGDFYVINGSKTFISNGTHCDLLVIVAKTDPSKGAAGVSLIVAET
Mflv_4601|M.gilvum_PYR-GCK TKASRVGDEYVVNGSKTFITNGAQADLIIVVAKTDPSAGANGISLVLVEG
MMAR_3132|M.marinum_M TKAILDGDEYVITGAKTFITNGQQADLIIVVAKTDPSQGAAGISLIVAEA
TH_3180|M.thermoresistible__bu TTAVRDGDEYIVNGSKTFITNGGSADMILLAVKTDPKAGARGISLLIVDL
MLBr_00737|M.leprae_Br4923 TRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHK
* * ** :::.* * :*:.* . : . ***. * *.* .:..
Mb2743c|M.bovis_AF2122/97 --GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLG-QEGMGFIYL
Rv2724c|M.tuberculosis_H37Rv --GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLG-QEGMGFIYL
MUL_3367|M.ulcerans_Agy99 --GMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLG-QEGMGFIYL
Mvan_2439|M.vanbaalenii_PYR-1 --GMAGFERGRKLDKIGLDAQDTAELSFTDVKVPVENLLG-EEGQGFIYL
MSMEG_5197|M.smegmatis_MC2_155 --GMEGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLG-KEGRGFYHL
MAB_1863|M.abscessus_ATCC_1997 KD-LPGFERGRVLEKVGQHGQDTRELFFTDMRVPIANRLGDKDGLGFYQL
MAV_2703|M.avium_104 DENLAGFERGRVLAKMGQHAQDTRELFFSDMRVPVANLLGAQEGLGFYQL
Mflv_4601|M.gilvum_PYR-GCK -D-RPGFRRGRVLDKVGQRGQDTSELYFEDVHIPVENLLGTTEGQGFIQL
MMAR_3132|M.marinum_M -D-RPGFRRGKVLDKIGQRGQDTSELFFDDVRVPRSHLLGETEGQGFIQL
TH_3180|M.thermoresistible__bu RD-CDGYQVTRVLDKVGQHGADTAELSFTDVRVPVANLLGAEEGKGFGQM
MLBr_00737|M.leprae_Br4923 --DDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIG-EPGTGFKTA
*: *:* . * ** * . :* . :* * **
Mb2743c|M.bovis_AF2122/97 MQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLL
Rv2724c|M.tuberculosis_H37Rv MQNLPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLL
MUL_3367|M.ulcerans_Agy99 MQNLPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVL
Mvan_2439|M.vanbaalenii_PYR-1 MQNLPQERISIAIMAAAAMEAVLDVTLQYTKERKAFGRPIGSQQNSRFLL
MSMEG_5197|M.smegmatis_MC2_155 MTNLPSERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLL
MAB_1863|M.abscessus_ATCC_1997 MEQLARERLIIAAVCSGMAEGALIEAIKYTKEREAFGKPLIKFQNTKFQL
MAV_2703|M.avium_104 MEQLARERLIIATICAALAEVAVLEAIKYSREREAFGRPIGKFQHTKFVL
Mflv_4601|M.gilvum_PYR-GCK MQQLPQERLILALGAVTVLETALEFTVEYTKDRHAFGKPVFAFQNTKFKL
MMAR_3132|M.marinum_M MTQLPQERLIVAVGAVAAMELAVEQTLKYTREREAFGRPVFGFQNTKFIL
TH_3180|M.thermoresistible__bu IDQLAQERLAVAAQAMGGMERAVDDTVAYTKSREAFGQSIFDFQNTAFEL
MLBr_00737|M.leprae_Br4923 LATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFML
: * * :. . . .. :: * :.*. **..: * * *
Mb2743c|M.bovis_AF2122/97 AELATEATVVRIMVDEFIKLHLAGKLTA-EQAAMAKWYATEKQVYLNDRC
Rv2724c|M.tuberculosis_H37Rv AELATEATVVRIMVDEFIKLHLAGKLTA-EQAAMAKWYATEKQVYLNDRC
MUL_3367|M.ulcerans_Agy99 AELATEATMVRIMVDESIELHLDGKLTA-EQAAMAKWYSTEKQVSLNDRC
Mvan_2439|M.vanbaalenii_PYR-1 AELSTEATVVRMMVDEFIKLHLQDKLTV-EQAAMAKWYSTEKQVHLIDRC
MSMEG_5197|M.smegmatis_MC2_155 AEMETELEVTENYIDRCLQGVVDGELTA-VEAAKAKWWATETAKKIVDNC
MAB_1863|M.abscessus_ATCC_1997 AELKAEVLSIKTTVDYCVQDYINGNNDP-ATASMAKLIAADKAVSVVDRC
MAV_2703|M.avium_104 AECKTEALAIKTMVDYAVGQYLDGKNDP-ATASMAKLFAAEKSDQIVDKC
Mflv_4601|M.gilvum_PYR-GCK AEVATDAHISRVFIDDCVARHLRGELDI-PTVAMAKWWTTERAMVALDDC
MMAR_3132|M.marinum_M AEAATETRIARVFLDYCIDLHLAGQLDV-QTVAMAKWWTTERAMKVLDDC
TH_3180|M.thermoresistible__bu AECATIARTCRAFFDQCVEAHLRGELDG-TDAAMAKYWLTDRQCEVVDRC
MLBr_00737|M.leprae_Br4923 ADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDA
*: . . .: : :* :: .
Mb2743c|M.bovis_AF2122/97 LQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
Rv2724c|M.tuberculosis_H37Rv LQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
MUL_3367|M.ulcerans_Agy99 LQLHGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
Mvan_2439|M.vanbaalenii_PYR-1 LQLHGGYGYMREYDVARAYLDARVQTIYGGTTEIMKEIIGRSLGV
MSMEG_5197|M.smegmatis_MC2_155 VQLHGGYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV
MAB_1863|M.abscessus_ATCC_1997 VQFFGGYGYMMEYPIARAYAAARVNKIYGGTSEIMKEIISRSL--
MAV_2703|M.avium_104 LQIFGGYGYMTEYPIANMYTASRVNRKYGRTSEIMKEIISRSL--
Mflv_4601|M.gilvum_PYR-GCK LQLHGGYGYMTEYPIGRMWADARVQKIYGGTNEIMKEIIARSL--
MMAR_3132|M.marinum_M LQLHGGYGYMTEYPISRLWVDQRVQKIYAGTNEVMKEIISRSL--
TH_3180|M.thermoresistible__bu VQLHGGYGYMREYLIARMYEDARVQRIYAGANEVMKQIIARSL--
MLBr_00737|M.leprae_Br4923 VQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
:*:.** ** :: : . :: : :.:: : ::.* *