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LDIEYTDSGTGSTILFVHGVYVTGAVWNDVVAELGEGFHCIAPTWPLGAHSTPTGGADLGAEAAARRIVH FMEALDLTDVTVVANDTGGGLVLASLGDPGLDTSRIARLVLTNCDSYEHFPPGSFAQIVKLCRLSSRVGG GIVRLLATGPGQSFFLKAVSKHPPSRERQREIFGAFATSGAARRDAVMVTASLDPALTLRAAPAIKAFDR PVTLTWGTEDKLFPLDHARRLRDAFPHAALIEIPDCSAFVMIDAPAKLAEAIRNG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2602 | - | - | 100% (265) | putative hydrolase |
| M. avium 104 | MAV_1840 | - | 3e-74 | 50.38% (264) | hydrolase, alpha/beta fold family protein, putative |
| M. avium 104 | MAV_5254 | - | 8e-29 | 32.84% (268) | hydrolase, alpha/beta hydrolase fold family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0079c | - | 2e-32 | 32.06% (262) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3236 | - | 3e-35 | 34.75% (282) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv0077c | - | 2e-32 | 32.06% (262) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0195c | - | 5e-39 | 37.64% (263) | putative hydrolase, alpha/beta hydrolase fold |
| M. marinum M | MMAR_2774 | - | 2e-34 | 36.68% (259) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_6763 | - | 3e-35 | 36.67% (270) | oxidoreductase |
| M. thermoresistible (build 8) | TH_3479 | - | 2e-78 | 54.02% (261) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_2973 | - | 1e-34 | 36.58% (257) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5859 | - | 8e-34 | 36.16% (271) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2602|M.avium_104 -----------MDIEYTDSG-TGS---TILFVHGVYVTGAVWNDVVAELG
TH_3479|M.thermoresistible__bu -MSATTITVDDAAIEYTDVG-GGP---PIVFVHGAYVTGALWDDVVTRLS
Mflv_3236|M.gilvum_PYR-GCK ---MSTVGVPSGTIAYEDTGGDGP---VMVFGHGLLMDGRQWRKVLPQLP
Mvan_5859|M.vanbaalenii_PYR-1 ---MFTADVPAGPIAYDDTGGDGP---VLVFGHGLLMDGRQWRKVIPRLP
MSMEG_6763|M.smegmatis_MC2_155 ---MPVIELPSGPIAYEDTGGDGP---VLVFGHGLLMDGRQWRKVIPLLP
MAB_0195c|M.abscessus_ATCC_199 ---MPTFESAAGPIQYRDSG-DGP---PIVFVHGLFVTGTMWRKIVEPLS
Mb0079c|M.bovis_AF2122/97 ---MSTIDISAGTIHYEATGPETG--RPVVFVHGYMMGGQLWRRVSERLA
Rv0077c|M.tuberculosis_H37Rv ---MSTIDISAGTIHYEATGPETG--RPVVFVHGYMMGGQLWRRVSERLA
MMAR_2774|M.marinum_M ---MAQVTLSQATIAYRVLGPENSPHPPVLFVHGILVDERLWSAVAEGLA
MUL_2973|M.ulcerans_Agy99 MAPMAQVTLSQATIAYRVLGPENSPHRPVLFVHGILVDDRLWSAVAEGLA
* * * ::* ** : * : *
MAV_2602|M.avium_104 EG-FHCIAPTWPLGAHSTPTGG-ADLGAEAAARRIVHFMEALDLTDVTVV
TH_3479|M.thermoresistible__bu RG-HRCIAPTWPFGAQRTPVGDSVDLDVVACGRRIIGLLEQLDLRDVTLV
Mflv_3236|M.gilvum_PYR-GCK E--YRCITPTLPMGAHTSPMRHDADLTETGMANILADFLDALDLDDVTLV
Mvan_5859|M.vanbaalenii_PYR-1 G--YRCITPTLPLGAHTVPMRDDADLTQTGVAGILADFLDALDLDDVTLV
MSMEG_6763|M.smegmatis_MC2_155 G--CRCITPTLPMGAHTAPMRPDADLTEQGVAGILADFLDALDLKDVTLV
MAB_0195c|M.abscessus_ATCC_199 GR-FRCIAPDLPLGAHKTPMNPGVELGPRAVAGLVRDLIVNLDLDDVTVV
Mb0079c|M.bovis_AF2122/97 GRGLRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLV
Rv0077c|M.tuberculosis_H37Rv GRGLRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLV
MMAR_2774|M.marinum_M AMGFRCILPTWPLGSHTIPANEGADLSPAGIAEMIHEFMVALDLADVTLV
MUL_2973|M.ulcerans_Agy99 AMGFRCILPTWPLGSHTIPANEGADLSPAGIAEMIHEFMVALDLADVTLV
:** * *:*:: * .: . . : .: *:* **.:*
MAV_2602|M.avium_104 ANDTGGGLVLASLGDPGLDTSRIARLVLTNCDSYEHFPPGSFAQIVKLCR
TH_3479|M.thermoresistible__bu ANDSGGGITLSALGILGLDWSRVSRLVFTNCDTFEHFPPKQFAPLVKLCR
Mflv_3236|M.gilvum_PYR-GCK LNDWGGG--QFMISE-GRDK-RIGRMVLASVTAFDNYPPEPARPAALLCR
Mvan_5859|M.vanbaalenii_PYR-1 LNDWGGG--QFVISE-GRDK-RIGRLVLVSCEAFDNFPPKPARPAALLCR
MSMEG_6763|M.smegmatis_MC2_155 LNDWGGG--QFLITD-GRDA-RIGRLVLASCTAFDNYPPAPARPAAALCR
MAB_0195c|M.abscessus_ATCC_199 ATDTGGAITQLLLAD-GCD--RIGRVVLTPCDSFDNFLPKSIRIFQYWAR
Mb0079c|M.bovis_AF2122/97 GNDTGGVVTQLVAVH---YPERLGALVLTSCDAFEHFPPPILKPVILAAK
Rv0077c|M.tuberculosis_H37Rv GNDTGGVVTQLVAVH---YPERLGALVLTSCDAFEHFPPPILKPVILAAK
MMAR_2774|M.marinum_M GNDTGGGLCQLAIDA---HPDLVGRLVLTNCDAFETFPPFPFPAVFTLLR
MUL_2973|M.ulcerans_Agy99 GNDTGGGLCQLAIDA---HPDLVGRLVLTNCDAFETFPPFPFPAVFTLLR
.* ** :. :*:. ::: : * :
MAV_2602|M.avium_104 LSSRVGGGIVRLLATGPGQSFFLKAVS----KHPPSRERQREIFGAFATS
TH_3479|M.thermoresistible__bu VAPPLGGAVLRLLATGPGLAFFKRAVT----RNGITGDRDDAIFGGFLSS
Mflv_3236|M.gilvum_PYR-GCK MPG--GGWVLSRMLGTRFFRHSRRAYG-AMAKSGLPDELFDAWFAPAVEN
Mvan_5859|M.vanbaalenii_PYR-1 FPG--GGWVLSRMLGTRLFRHSRRAYG-ALAKSGIPDAMFDEWFRPAVES
MSMEG_6763|M.smegmatis_MC2_155 LPG--GGRLLTKMFGTRFFRHSRLAYG-ALSKAGLPDGLFDEWFRPAVEN
MAB_0195c|M.abscessus_ATCC_199 VPG--TDFVLQPFK----LRLARRALGNTLAKHSIPDAVLGEWVAPLLAQ
Mb0079c|M.bovis_AF2122/97 SAT----LFRAAIQVMRAPAARNR--AYAGLSHHNIDHLTRAWVRPALSN
Rv0077c|M.tuberculosis_H37Rv SAT----LFRAAIQVMRAPAARNR--AYAGLSHHNIDHLTRAWVRPALSN
MMAR_2774|M.marinum_M GPR----SIKPLFAAMGLRPLRHSPLGYGLLLNKPDAALTASWLQPCRTD
MUL_2973|M.ulcerans_Agy99 RPR----SIKTLFAAMGLRPLRHSPLGFGLLLNKPDAALTASWLQPCRTD
. . : . .
MAV_2602|M.avium_104 GAARRDAVMVTASLDPAL-TLRAAPAIKAFDRPVTLTWGTEDKLFPLDHA
TH_3479|M.thermoresistible__bu AAVRREAVRFSAGLHPQH-TAAAAQAIGKWTKPVLVLWGTADDLFPVSHA
Mflv_3236|M.gilvum_PYR-GCK PAIRRDLVKFATGAPPRARLLEMSEQMRTFDRPVLVIWAREDRMMPLEHA
Mvan_5859|M.vanbaalenii_PYR-1 AAIRRDLVKFATGSPSRRRLLELSENLATFDRPVLVVWAREDRMMPLQHA
MSMEG_6763|M.smegmatis_MC2_155 AAVRRDLVKFATGAPPRRRLLELSERLRTFTRPVLVVWAREDRMMPLDHA
MAB_0195c|M.abscessus_ATCC_199 QGIRRDVRAFLRGIDNRD-TLAAAEILRGFERPVLLLWPRTLPFFPFAHA
Mb0079c|M.bovis_AF2122/97 PAIAEDLRQLSLSLRTEV-TTAVAARLPEFDKPALIAWSADDVFFALENG
Rv0077c|M.tuberculosis_H37Rv PAIAEDLRQLSLSLRTEV-TTAVAARLPEFDKPALIAWSADDVFFALENG
MMAR_2774|M.marinum_M ARICDDLATLLRHVAATD-LTEVSTRFAQFTKPVTLVWGMGDRCFKPTLA
MUL_2973|M.ulcerans_Agy99 ARICDDLATLLRHVAATD-LTEVSTRFAQFTKPVTLVWGMGDRCFKPTLA
: . : : : :*. : * : .
MAV_2602|M.avium_104 RRLRDAFPHAALIEIPDCSAFVMIDAPAKLAEAIRNG--------
TH_3479|M.thermoresistible__bu QRLAEAFPNSRLRLIEGSSTYVMLDHPSETADAIGTFIAGRS---
Mflv_3236|M.gilvum_PYR-GCK DRLVELYPDATKIVVDDSWTLIPEDQPAAMAQALRDFVSLSPRES
Mvan_5859|M.vanbaalenii_PYR-1 DRLVELFSDARKVVVDDSWTLIPEDQPEIMAQLLRDFVG------
MSMEG_6763|M.smegmatis_MC2_155 DRLVELFPDATKVIVDDSWTLIPEDQPEVMAGALREFVG------
MAB_0195c|M.abscessus_ATCC_199 ERWLRLLPNAKLVEVPDSYTFVSEDQPELMVREIETFVGQRV---
Mb0079c|M.bovis_AF2122/97 QRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT----
Rv0077c|M.tuberculosis_H37Rv QRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT----
MMAR_2774|M.marinum_M RRMAQLFPDASIIEVPGSKTFVALNEPAAVINAISTVGAHHG---
MUL_2973|M.ulcerans_Agy99 RRMAQLFPDASIIEVPGSKTFVALNEPAAVINAISTVGAHHG---
* . : : .. : : * :