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STIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRGLRCIAPTWPLGAHPKPLRPGADQ TIGGVAGIVADVLAALELKDVVLVGNDTGGVVTQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAA KSATLFRAAIQVMRAPAARNRAYAGLSHHNIDHLTRAWVRPALSNPAIAEDLRQLSLSLRTEVTTAVAAR LPEFDKPALIAWSADDVFFALENGQRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0077c | - | - | 100% (276) | PROBABLE OXIDOREDUCTASE |
| M. tuberculosis H37Rv | Rv2715 | - | 1e-11 | 23.74% (257) | hydrolase |
| M. tuberculosis H37Rv | Rv1833c | - | 3e-11 | 28.57% (273) | haloalkane dehalogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0079c | - | 1e-157 | 100.00% (276) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3236 | - | 1e-37 | 35.53% (273) | alpha/beta hydrolase fold |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0195c | - | 4e-41 | 35.16% (273) | putative hydrolase, alpha/beta hydrolase fold |
| M. marinum M | MMAR_0223 | - | 1e-124 | 79.35% (276) | oxidoreductase |
| M. avium 104 | MAV_5254 | - | 1e-126 | 80.07% (276) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_6763 | - | 2e-38 | 37.00% (273) | oxidoreductase |
| M. thermoresistible (build 8) | TH_3479 | - | 6e-37 | 33.93% (280) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_4891 | - | 1e-123 | 78.62% (276) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5859 | - | 1e-39 | 38.10% (273) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3236|M.gilvum_PYR-GCK --MSTVGVPSGTIAYEDTGG-DGPVMVFGHGLLMDGRQWRKVLPQLPE--
Mvan_5859|M.vanbaalenii_PYR-1 --MFTADVPAGPIAYDDTGG-DGPVLVFGHGLLMDGRQWRKVIPRLPG--
MSMEG_6763|M.smegmatis_MC2_155 --MPVIELPSGPIAYEDTGG-DGPVLVFGHGLLMDGRQWRKVIPLLPG--
MAB_0195c|M.abscessus_ATCC_199 --MPTFESAAGPIQYRDSG--DGPPIVFVHGLFVTGTMWRKIVEPLSGR-
Rv0077c|M.tuberculosis_H37Rv --MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRG
Mb0079c|M.bovis_AF2122/97 --MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRG
MMAR_0223|M.marinum_M --MPTIDINAGTIHYEVTGPEHGRPVMFVHGYLMGGQLWRQVSERLAKRG
MUL_4891|M.ulcerans_Agy99 --MPTIDINAGTIHYEITGPEHGRPVMFVHGYLMGGQLWRQVSERLAEWG
MAV_5254|M.avium_104 --MSTIDISAGTIHYEATGPADGRPVVFVHGYLMGGQLWRQVGDRLAGRG
TH_3479|M.thermoresistible__bu MSATTITVDDAAIEYTDVGG--GPPIVFVHGAYVTGALWDDVVTRLSRG-
. ..* * * * ::* ** : * * : *.
Mflv_3236|M.gilvum_PYR-GCK YRCITPTLPMGAHTSPMRHDADLTETGMANILADFLDALDLDDVTLVLND
Mvan_5859|M.vanbaalenii_PYR-1 YRCITPTLPLGAHTVPMRDDADLTQTGVAGILADFLDALDLDDVTLVLND
MSMEG_6763|M.smegmatis_MC2_155 CRCITPTLPMGAHTAPMRPDADLTEQGVAGILADFLDALDLKDVTLVLND
MAB_0195c|M.abscessus_ATCC_199 FRCIAPDLPLGAHKTPMNPGVELGPRAVAGLVRDLIVNLDLDDVTVVATD
Rv0077c|M.tuberculosis_H37Rv LRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGND
Mb0079c|M.bovis_AF2122/97 LRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGND
MMAR_0223|M.marinum_M LRCFAPTWPLGAHPRALGPDADRSITGVGDLVADVLATLDLHDVVLVGND
MUL_4891|M.ulcerans_Agy99 LRCFAPTWPLGTHPRALGPDADRSITGVGDLVADVLATLDLHDVVLVGND
MAV_5254|M.avium_104 LRCIAPTWPMGAHPEPLRRGADRTITGVAAMVAELLSALDLEDVVLVGND
TH_3479|M.thermoresistible__bu HRCIAPTWPFGAQRTPVGDSVDLDVVACGRRIIGLLEQLDLRDVTLVAND
**::* *:*:: .: ..: . . : .: *:* **.:* .*
Mflv_3236|M.gilvum_PYR-GCK WGGG----QFMISEGRDKRIGRMVLASVTAFDNYPPEPARPAALLCRMPG
Mvan_5859|M.vanbaalenii_PYR-1 WGGG----QFVISEGRDKRIGRLVLVSCEAFDNFPPKPARPAALLCRFPG
MSMEG_6763|M.smegmatis_MC2_155 WGGG----QFLITDGRDARIGRLVLASCTAFDNYPPAPARPAAALCRLPG
MAB_0195c|M.abscessus_ATCC_199 TGGAIT--QLLLADGCD-RIGRVVLTPCDSFDNFLPKSIRIFQYWARVPG
Rv0077c|M.tuberculosis_H37Rv TGGVV---TQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSAT
Mb0079c|M.bovis_AF2122/97 TGGVV---TQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSAT
MMAR_0223|M.marinum_M TGGVV---AQLVAVRHPERLGALVLTSCDAFEHFPPPILKPVILAAKSKK
MUL_4891|M.ulcerans_Agy99 TGGVV---AQLVAVHHPERLGALVLTSCDAFEHFPPPILKPVILAAKSKK
MAV_5254|M.avium_104 TGGVV---SQLVAVHHRERLGALVLTSCDAFEHFPPPVLRPVILAAKSKA
TH_3479|M.thermoresistible__bu SGGGITLSALGILGLDWSRVSRLVFTNCDTFEHFPPKQFAPLVKLCRVAP
** : *:. :*:. :*::: * .:
Mflv_3236|M.gilvum_PYR-GCK GGWVLSRMLGTRFFRHSRRAYG-AMAKSGLPDELFDAWFAPAVENPAIRR
Mvan_5859|M.vanbaalenii_PYR-1 GGWVLSRMLGTRLFRHSRRAYG-ALAKSGIPDAMFDEWFRPAVESAAIRR
MSMEG_6763|M.smegmatis_MC2_155 GGRLLTKMFGTRFFRHSRLAYG-ALSKAGLPDGLFDEWFRPAVENAAVRR
MAB_0195c|M.abscessus_ATCC_199 TDFVLQPFK----LRLARRALGNTLAKHSIPDAVLGEWVAPLLAQQGIRR
Rv0077c|M.tuberculosis_H37Rv --LFRAAIQVMRAPAARNRAYA--GLSHHNIDHLTRAWVRPALSNPAIAE
Mb0079c|M.bovis_AF2122/97 --LFRAAIQVMRAPAARNRAYA--GLSHHNIDHLTRAWVRPALSNPAIAE
MMAR_0223|M.marinum_M --MFRAAIQTMRSPAARRRAYG--DLAHADIDELAQRWVQPALSNPAIAE
MUL_4891|M.ulcerans_Agy99 --MFRAAIQTMRSPAARRRTYG--DLAHADIDELAQRWVQPALSNPAIAE
MAV_5254|M.avium_104 --TFRAVAQAMRAPAVRKRAFD--GLAHSNIDALTELWVRPALSLPAVAE
TH_3479|M.thermoresistible__bu --PLGGAVLRLLATGPGLAFFKRAVTRNGITGDRDDAIFGGFLSSAAVRR
. . . : .: .
Mflv_3236|M.gilvum_PYR-GCK DLVKFATGAPPRARLLEMSEQMRTFDRPVLVIWAREDRMMPLEHADRLVE
Mvan_5859|M.vanbaalenii_PYR-1 DLVKFATGSPSRRRLLELSENLATFDRPVLVVWAREDRMMPLQHADRLVE
MSMEG_6763|M.smegmatis_MC2_155 DLVKFATGAPPRRRLLELSERLRTFTRPVLVVWAREDRMMPLDHADRLVE
MAB_0195c|M.abscessus_ATCC_199 DVRAFLRGIDNRD-TLAAAEILRGFERPVLLLWPRTLPFFPFAHAERWLR
Rv0077c|M.tuberculosis_H37Rv DLRQLSLS-LRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA
Mb0079c|M.bovis_AF2122/97 DLRQLSLS-LRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA
MMAR_0223|M.marinum_M DLRQLTLS-LHTDVTRGVAARLPEFSKPALIAWSADDKFFALEDGRRLAA
MUL_4891|M.ulcerans_Agy99 DLRQLTLS-LHTDVTRGVAARLPEFSKPALIAWSADDKFFALEDGRRLAA
MAV_5254|M.avium_104 DLRRFTLS-LRTEVTTAAAARLYDFDKPTLIAWSADDVFFAQEDGARLAA
TH_3479|M.thermoresistible__bu EAVRFSAG-LHPQHTAAAAQAIGKWTKPVLVLWGTADDLFPVSHAQRLAE
: : . : : : :*.*: * ::. .. *
Mflv_3236|M.gilvum_PYR-GCK LYPDATKIVVDDSWTLIPEDQPAAMAQALRDFVSLSPRES
Mvan_5859|M.vanbaalenii_PYR-1 LFSDARKVVVDDSWTLIPEDQPEIMAQLLRDFVG------
MSMEG_6763|M.smegmatis_MC2_155 LFPDATKVIVDDSWTLIPEDQPEVMAGALREFVG------
MAB_0195c|M.abscessus_ATCC_199 LLPNAKLVEVPDSYTFVSEDQPELMVREIETFVGQRV---
Rv0077c|M.tuberculosis_H37Rv TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT----
Mb0079c|M.bovis_AF2122/97 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT----
MMAR_0223|M.marinum_M TIPNARLELIEGARTFSMLDRPDRLADLLSAVAVRT----
MUL_4891|M.ulcerans_Agy99 TIPNARLELIEGARTFSMLDRPDRLADLLSAVAVRT----
MAV_5254|M.avium_104 TIPNARHEVIAGARTFSMVDQPDRLADLLSTVAVRT----
TH_3479|M.thermoresistible__bu AFPNSRLRLIEGSSTYVMLDHPSETADAIGTFIAGRS---
. : : .: * * * . : .