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VAPMAQVTLSQATIAYRVLGPENSPHRPVLFVHGILVDDRLWSAVAEGLAAMGFRCILPTWPLGSHTIPA NEGADLSPAGIAEMIHEFMVALDLADVTLVGNDTGGGLCQLAIDAHPDLVGRLVLTNCDAFETFPPFPFP AVFTLLRRPRSIKTLFAAMGLRPLRHSPLGFGLLLNKPDAALTASWLQPCRTDARICDDLATLLRHVAAT DLTEVSTRFAQFTKPVTLVWGMGDRCFKPTLARRMAQLFPDASIIEVPGSKTFVALNEPAAVINAISTVG AHHG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2973 | - | - | 100% (284) | oxidoreductase |
| M. ulcerans Agy99 | MUL_4891 | - | 2e-46 | 37.41% (278) | oxidoreductase |
| M. ulcerans Agy99 | MUL_3358 | - | 5e-08 | 23.74% (278) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0079c | - | 3e-46 | 37.05% (278) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3236 | - | 2e-36 | 35.38% (277) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv0077c | - | 3e-46 | 37.05% (278) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0195c | - | 6e-36 | 34.26% (251) | putative hydrolase, alpha/beta hydrolase fold |
| M. marinum M | MMAR_2774 | - | 1e-160 | 98.22% (281) | oxidoreductase |
| M. avium 104 | MAV_5254 | - | 1e-45 | 36.23% (276) | hydrolase, alpha/beta hydrolase fold family protein |
| M. smegmatis MC2 155 | MSMEG_6763 | - | 3e-39 | 38.27% (277) | oxidoreductase |
| M. thermoresistible (build 8) | TH_3479 | - | 4e-32 | 33.56% (289) | PUTATIVE alpha/beta hydrolase fold |
| M. vanbaalenii PYR-1 | Mvan_5859 | - | 1e-37 | 39.43% (246) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3236|M.gilvum_PYR-GCK ---MSTVGVPSGTIAYEDTGGDGP---VMVFGHGLLMDGRQWRKVLPQLP
Mvan_5859|M.vanbaalenii_PYR-1 ---MFTADVPAGPIAYDDTGGDGP---VLVFGHGLLMDGRQWRKVIPRLP
MSMEG_6763|M.smegmatis_MC2_155 ---MPVIELPSGPIAYEDTGGDGP---VLVFGHGLLMDGRQWRKVIPLLP
MAB_0195c|M.abscessus_ATCC_199 ---MPTFESAAGPIQYRDSG-DGP---PIVFVHGLFVTGTMWRKIVEPLS
TH_3479|M.thermoresistible__bu -MSATTITVDDAAIEYTDVG-GGP---PIVFVHGAYVTGALWDDVVTRLS
MUL_2973|M.ulcerans_Agy99 MAPMAQVTLSQATIAYRVLGPENSPHRPVLFVHGILVDDRLWSAVAEGLA
MMAR_2774|M.marinum_M ---MAQVTLSQATIAYRVLGPENSPHPPVLFVHGILVDERLWSAVAEGLA
Mb0079c|M.bovis_AF2122/97 ---MSTIDISAGTIHYEATGPETG--RPVVFVHGYMMGGQLWRRVSERLA
Rv0077c|M.tuberculosis_H37Rv ---MSTIDISAGTIHYEATGPETG--RPVVFVHGYMMGGQLWRRVSERLA
MAV_5254|M.avium_104 ---MSTIDISAGTIHYEATGPADG--RPVVFVHGYLMGGQLWRQVGDRLA
..* * * ::* ** : * : *.
Mflv_3236|M.gilvum_PYR-GCK E--YRCITPTLPMGAHTSPMRHDADLTETGMANILADFLDALDLDDVTLV
Mvan_5859|M.vanbaalenii_PYR-1 G--YRCITPTLPLGAHTVPMRDDADLTQTGVAGILADFLDALDLDDVTLV
MSMEG_6763|M.smegmatis_MC2_155 G--CRCITPTLPMGAHTAPMRPDADLTEQGVAGILADFLDALDLKDVTLV
MAB_0195c|M.abscessus_ATCC_199 GR-FRCIAPDLPLGAHKTPMNPGVELGPRAVAGLVRDLIVNLDLDDVTVV
TH_3479|M.thermoresistible__bu RG-HRCIAPTWPFGAQRTPVGDSVDLDVVACGRRIIGLLEQLDLRDVTLV
MUL_2973|M.ulcerans_Agy99 AMGFRCILPTWPLGSHTIPANEGADLSPAGIAEMIHEFMVALDLADVTLV
MMAR_2774|M.marinum_M AMGFRCILPTWPLGSHTIPANEGADLSPAGIAEMIHEFMVALDLADVTLV
Mb0079c|M.bovis_AF2122/97 GRGLRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLV
Rv0077c|M.tuberculosis_H37Rv GRGLRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLV
MAV_5254|M.avium_104 GRGLRCIAPTWPMGAHPEPLRRGADRTITGVAAMVAELLSALDLEDVVLV
*** * *:*:: * ..: . . : .: *:* **.:*
Mflv_3236|M.gilvum_PYR-GCK LNDWGGG---QFMISEGRDK-RIGRMVLASVTAFDNYPPEPARPAALLCR
Mvan_5859|M.vanbaalenii_PYR-1 LNDWGGG---QFVISEGRDK-RIGRLVLVSCEAFDNFPPKPARPAALLCR
MSMEG_6763|M.smegmatis_MC2_155 LNDWGGG---QFLITDGRDA-RIGRLVLASCTAFDNYPPAPARPAAALCR
MAB_0195c|M.abscessus_ATCC_199 ATDTGGAI-TQLLLADGCD--RIGRVVLTPCDSFDNFLPKSIRIFQYWAR
TH_3479|M.thermoresistible__bu ANDSGGGITLSALGILGLDWSRVSRLVFTNCDTFEHFPPKQFAPLVKLCR
MUL_2973|M.ulcerans_Agy99 GNDTGGG---LCQLAIDAHPDLVGRLVLTNCDAFETFPPFPFPAVFTLLR
MMAR_2774|M.marinum_M GNDTGGG---LCQLAIDAHPDLVGRLVLTNCDAFETFPPFPFPAVFTLLR
Mb0079c|M.bovis_AF2122/97 GNDTGGV---VTQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAK
Rv0077c|M.tuberculosis_H37Rv GNDTGGV---VTQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAK
MAV_5254|M.avium_104 GNDTGGV---VSQLVAVHHRERLGALVLTSCDAFEHFPPPVLRPVILAAK
.* ** :. :*:. :*: : * :
Mflv_3236|M.gilvum_PYR-GCK MPG--GGWVLSRMLGTRFFRHSRRAYG-AMAKSGLPDELFDAWFAPAVEN
Mvan_5859|M.vanbaalenii_PYR-1 FPG--GGWVLSRMLGTRLFRHSRRAYG-ALAKSGIPDAMFDEWFRPAVES
MSMEG_6763|M.smegmatis_MC2_155 LPG--GGRLLTKMFGTRFFRHSRLAYG-ALSKAGLPDGLFDEWFRPAVEN
MAB_0195c|M.abscessus_ATCC_199 VPG--TDFVLQPFK----LRLARRALGNTLAKHSIPDAVLGEWVAPLLAQ
TH_3479|M.thermoresistible__bu VAPPLGGAVLRLLATGPGLAFFKRAVT----RNGITGDRDDAIFGGFLSS
MUL_2973|M.ulcerans_Agy99 RPR----SIKTLFAAMGLRPLRHSPLGFGLLLNKPDAALTASWLQPCRTD
MMAR_2774|M.marinum_M GPR----SIKPLFAAMGLRPLRHSPLGYGLLLNKPDAALTASWLQPCRTD
Mb0079c|M.bovis_AF2122/97 SAT----LFRAAIQVMRAPAARNR--AYAGLSHHNIDHLTRAWVRPALSN
Rv0077c|M.tuberculosis_H37Rv SAT----LFRAAIQVMRAPAARNR--AYAGLSHHNIDHLTRAWVRPALSN
MAV_5254|M.avium_104 SKA----TFRAVAQAMRAPAVRKR--AFDGLAHSNIDALTELWVRPALSL
. . .
Mflv_3236|M.gilvum_PYR-GCK PAIRRDLVKFATGAPPRARLLEMSEQMRTFDRPVLVIWAREDRMMPLEHA
Mvan_5859|M.vanbaalenii_PYR-1 AAIRRDLVKFATGSPSRRRLLELSENLATFDRPVLVVWAREDRMMPLQHA
MSMEG_6763|M.smegmatis_MC2_155 AAVRRDLVKFATGAPPRRRLLELSERLRTFTRPVLVVWAREDRMMPLDHA
MAB_0195c|M.abscessus_ATCC_199 QGIRRDVRAFLRGIDNRD-TLAAAEILRGFERPVLLLWPRTLPFFPFAHA
TH_3479|M.thermoresistible__bu AAVRREAVRFSAGLHPQH-TAAAAQAIGKWTKPVLVLWGTADDLFPVSHA
MUL_2973|M.ulcerans_Agy99 ARICDDLATLLRHVAATD-LTEVSTRFAQFTKPVTLVWGMGDRCFKPTLA
MMAR_2774|M.marinum_M ARICDDLATLLRHVAATD-LTEVSTRFAQFTKPVTLVWGMGDRCFKPTLA
Mb0079c|M.bovis_AF2122/97 PAIAEDLRQLSLSLRTEV-TTAVAARLPEFDKPALIAWSADDVFFALENG
Rv0077c|M.tuberculosis_H37Rv PAIAEDLRQLSLSLRTEV-TTAVAARLPEFDKPALIAWSADDVFFALENG
MAV_5254|M.avium_104 PAVAEDLRRFTLSLRTEV-TTAAAARLYDFDKPTLIAWSADDVFFAQEDG
: : : : : : :*. : * : .
Mflv_3236|M.gilvum_PYR-GCK DRLVELYPDATKIVVDDSWTLIPEDQPAAMAQALRDFVSLSPRES
Mvan_5859|M.vanbaalenii_PYR-1 DRLVELFSDARKVVVDDSWTLIPEDQPEIMAQLLRDFVG------
MSMEG_6763|M.smegmatis_MC2_155 DRLVELFPDATKVIVDDSWTLIPEDQPEVMAGALREFVG------
MAB_0195c|M.abscessus_ATCC_199 ERWLRLLPNAKLVEVPDSYTFVSEDQPELMVREIETFVGQRV---
TH_3479|M.thermoresistible__bu QRLAEAFPNSRLRLIEGSSTYVMLDHPSETADAIGTFIAGRS---
MUL_2973|M.ulcerans_Agy99 RRMAQLFPDASIIEVPGSKTFVALNEPAAVINAISTVGAHHG---
MMAR_2774|M.marinum_M RRMAQLFPDASIIEVPGSKTFVALNEPAAVINAISTVGAHHG---
Mb0079c|M.bovis_AF2122/97 QRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT----
Rv0077c|M.tuberculosis_H37Rv QRLAATIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT----
MAV_5254|M.avium_104 ARLAATIPNARHEVIAGARTFSMVDQPDRLADLLSTVAVRT----
* . : : .: * : * : .