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M. avium 104 MAV_5254 (-)

MSTIDISAGTIHYEATGPADGRPVVFVHGYLMGGQLWRQVGDRLAGRGLRCIAPTWPMGAHPEPLRRGAD
RTITGVAAMVAELLSALDLEDVVLVGNDTGGVVSQLVAVHHRERLGALVLTSCDAFEHFPPPVLRPVILA
AKSKATFRAVAQAMRAPAVRKRAFDGLAHSNIDALTELWVRPALSLPAVAEDLRRFTLSLRTEVTTAAAA
RLYDFDKPTLIAWSADDVFFAQEDGARLAATIPNARHEVIAGARTFSMVDQPDRLADLLSTVAVRT

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_5254	-	-	100% (276)	hydrolase, alpha/beta hydrolase fold family protein
M. avium 104	MAV_1840	-	6e-39	36.67% (270)	hydrolase, alpha/beta fold family protein, putative
M. avium 104	MAV_2602	-	9e-29	32.84% (268)	putative hydrolase

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	Mb0079c	-	1e-126	80.07% (276)	oxidoreductase
M. gilvum PYR-GCK	Mflv_3236	-	2e-40	36.63% (273)	alpha/beta hydrolase fold
M. tuberculosis H37Rv	Rv0077c	-	1e-126	80.07% (276)	oxidoreductase
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_0195c	-	2e-41	36.03% (272)	putative hydrolase, alpha/beta hydrolase fold
M. marinum M	MMAR_0223	-	1e-117	74.64% (276)	oxidoreductase
M. smegmatis MC2 155	MSMEG_6763	-	4e-38	37.23% (274)	oxidoreductase
M. thermoresistible (build 8)	TH_3479	-	4e-37	35.13% (279)	PUTATIVE alpha/beta hydrolase fold
M. ulcerans Agy99	MUL_4891	-	1e-116	73.91% (276)	oxidoreductase
M. vanbaalenii PYR-1	Mvan_5859	-	3e-44	40.88% (274)	alpha/beta hydrolase fold

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3236|M.gilvum_PYR-GCK          --MSTVGVPSGTIAYEDTGG-DGPVMVFGHGLLMDGRQWRKVLPQLPE--
Mvan_5859|M.vanbaalenii_PYR-1       --MFTADVPAGPIAYDDTGG-DGPVLVFGHGLLMDGRQWRKVIPRLPG--
MSMEG_6763|M.smegmatis_MC2_155      --MPVIELPSGPIAYEDTGG-DGPVLVFGHGLLMDGRQWRKVIPLLPG--
MAB_0195c|M.abscessus_ATCC_199      --MPTFESAAGPIQYRDSG--DGPPIVFVHGLFVTGTMWRKIVEPLSGR-
MMAR_0223|M.marinum_M               --MPTIDINAGTIHYEVTGPEHGRPVMFVHGYLMGGQLWRQVSERLAKRG
MUL_4891|M.ulcerans_Agy99           --MPTIDINAGTIHYEITGPEHGRPVMFVHGYLMGGQLWRQVSERLAEWG
Mb0079c|M.bovis_AF2122/97           --MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRG
Rv0077c|M.tuberculosis_H37Rv        --MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRG
MAV_5254|M.avium_104                --MSTIDISAGTIHYEATGPADGRPVVFVHGYLMGGQLWRQVGDRLAGRG
TH_3479|M.thermoresistible__bu      MSATTITVDDAAIEYTDVGG--GPPIVFVHGAYVTGALWDDVVTRLSRG-
                                        .     ..* *   *   *  ::* **  : *  *  :   *.   

Mflv_3236|M.gilvum_PYR-GCK          YRCITPTLPMGAHTSPMRHDADLTETGMANILADFLDALDLDDVTLVLND
Mvan_5859|M.vanbaalenii_PYR-1       YRCITPTLPLGAHTVPMRDDADLTQTGVAGILADFLDALDLDDVTLVLND
MSMEG_6763|M.smegmatis_MC2_155      CRCITPTLPMGAHTAPMRPDADLTEQGVAGILADFLDALDLKDVTLVLND
MAB_0195c|M.abscessus_ATCC_199      FRCIAPDLPLGAHKTPMNPGVELGPRAVAGLVRDLIVNLDLDDVTVVATD
MMAR_0223|M.marinum_M               LRCFAPTWPLGAHPRALGPDADRSITGVGDLVADVLATLDLHDVVLVGND
MUL_4891|M.ulcerans_Agy99           LRCFAPTWPLGTHPRALGPDADRSITGVGDLVADVLATLDLHDVVLVGND
Mb0079c|M.bovis_AF2122/97           LRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGND
Rv0077c|M.tuberculosis_H37Rv        LRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGND
MAV_5254|M.avium_104                LRCIAPTWPMGAHPEPLRRGADRTITGVAAMVAELLSALDLEDVVLVGND
TH_3479|M.thermoresistible__bu      HRCIAPTWPFGAQRTPVGDSVDLDVVACGRRIIGLLEQLDLRDVTLVAND
                                     **::*  *:*::  .:  ..:    . .  :  .:  *:* **.:* .*

Mflv_3236|M.gilvum_PYR-GCK          WGGG----QFMISEGRDKRIGRMVLASVTAFDNYPPEPARPAALLCRMPG
Mvan_5859|M.vanbaalenii_PYR-1       WGGG----QFVISEGRDKRIGRLVLVSCEAFDNFPPKPARPAALLCRFPG
MSMEG_6763|M.smegmatis_MC2_155      WGGG----QFLITDGRDARIGRLVLASCTAFDNYPPAPARPAAALCRLPG
MAB_0195c|M.abscessus_ATCC_199      TGGAIT--QLLLADGCD-RIGRVVLTPCDSFDNFLPKSIRIFQYWARVPG
MMAR_0223|M.marinum_M               TGGVV---AQLVAVRHPERLGALVLTSCDAFEHFPPPILKPVILAAKSKK
MUL_4891|M.ulcerans_Agy99           TGGVV---AQLVAVHHPERLGALVLTSCDAFEHFPPPILKPVILAAKSKK
Mb0079c|M.bovis_AF2122/97           TGGVV---TQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSAT
Rv0077c|M.tuberculosis_H37Rv        TGGVV---TQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSAT
MAV_5254|M.avium_104                TGGVV---SQLVAVHHRERLGALVLTSCDAFEHFPPPVLRPVILAAKSKA
TH_3479|M.thermoresistible__bu      SGGGITLSALGILGLDWSRVSRLVFTNCDTFEHFPPKQFAPLVKLCRVAP
                                     **        :      *:. :*:.   :*::: *         .:   

Mflv_3236|M.gilvum_PYR-GCK          GGWVLSRMLGTRFFRHSRRAYG-AMAKSGLPDELFDAWFAPAVENPAIRR
Mvan_5859|M.vanbaalenii_PYR-1       GGWVLSRMLGTRLFRHSRRAYG-ALAKSGIPDAMFDEWFRPAVESAAIRR
MSMEG_6763|M.smegmatis_MC2_155      GGRLLTKMFGTRFFRHSRLAYG-ALSKAGLPDGLFDEWFRPAVENAAVRR
MAB_0195c|M.abscessus_ATCC_199      TDFVLQPFK----LRLARRALGNTLAKHSIPDAVLGEWVAPLLAQQGIRR
MMAR_0223|M.marinum_M               --MFRAAIQTMRSPAARRRAYG--DLAHADIDELAQRWVQPALSNPAIAE
MUL_4891|M.ulcerans_Agy99           --MFRAAIQTMRSPAARRRTYG--DLAHADIDELAQRWVQPALSNPAIAE
Mb0079c|M.bovis_AF2122/97           --LFRAAIQVMRAPAARNRAYA--GLSHHNIDHLTRAWVRPALSNPAIAE
Rv0077c|M.tuberculosis_H37Rv        --LFRAAIQVMRAPAARNRAYA--GLSHHNIDHLTRAWVRPALSNPAIAE
MAV_5254|M.avium_104                --TFRAVAQAMRAPAVRKRAFD--GLAHSNIDALTELWVRPALSLPAVAE
TH_3479|M.thermoresistible__bu      --PLGGAVLRLLATGPGLAFFKRAVTRNGITGDRDDAIFGGFLSSAAVRR
                                       .                           .      .   :   .: .

Mflv_3236|M.gilvum_PYR-GCK          DLVKFATGAPPRARLLEMSEQMRTFDRPVLVIWAREDRMMPLEHADRLVE
Mvan_5859|M.vanbaalenii_PYR-1       DLVKFATGSPSRRRLLELSENLATFDRPVLVVWAREDRMMPLQHADRLVE
MSMEG_6763|M.smegmatis_MC2_155      DLVKFATGAPPRRRLLELSERLRTFTRPVLVVWAREDRMMPLDHADRLVE
MAB_0195c|M.abscessus_ATCC_199      DVRAFLRGIDNRD-TLAAAEILRGFERPVLLLWPRTLPFFPFAHAERWLR
MMAR_0223|M.marinum_M               DLRQLTLS-LHTDVTRGVAARLPEFSKPALIAWSADDKFFALEDGRRLAA
MUL_4891|M.ulcerans_Agy99           DLRQLTLS-LHTDVTRGVAARLPEFSKPALIAWSADDKFFALEDGRRLAA
Mb0079c|M.bovis_AF2122/97           DLRQLSLS-LRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA
Rv0077c|M.tuberculosis_H37Rv        DLRQLSLS-LRTEVTTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA
MAV_5254|M.avium_104                DLRRFTLS-LRTEVTTAAAARLYDFDKPTLIAWSADDVFFAQEDGARLAA
TH_3479|M.thermoresistible__bu      EAVRFSAG-LHPQHTAAAAQAIGKWTKPVLVLWGTADDLFPVSHAQRLAE
                                    :   :  .          :  :  : :*.*: *     ::.  .. *   

Mflv_3236|M.gilvum_PYR-GCK          LYPDATKIVVDDSWTLIPEDQPAAMAQALRDFVSLSPRES
Mvan_5859|M.vanbaalenii_PYR-1       LFSDARKVVVDDSWTLIPEDQPEIMAQLLRDFVG------
MSMEG_6763|M.smegmatis_MC2_155      LFPDATKVIVDDSWTLIPEDQPEVMAGALREFVG------
MAB_0195c|M.abscessus_ATCC_199      LLPNAKLVEVPDSYTFVSEDQPELMVREIETFVGQRV---
MMAR_0223|M.marinum_M               TIPNARLELIEGARTFSMLDRPDRLADLLSAVAVRT----
MUL_4891|M.ulcerans_Agy99           TIPNARLELIEGARTFSMLDRPDRLADLLSAVAVRT----
Mb0079c|M.bovis_AF2122/97           TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT----
Rv0077c|M.tuberculosis_H37Rv        TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT----
MAV_5254|M.avium_104                TIPNARHEVIAGARTFSMVDQPDRLADLLSTVAVRT----
TH_3479|M.thermoresistible__bu      AFPNSRLRLIEGSSTYVMLDHPSETADAIGTFIAGRS---
                                      . :    : .: *    * *   .  :  .