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ASIAVGDVEIDYVDAGSGPVVVFVHGAYVTGLLWQDVVDRLSDSHRCIAPTLPFGAQAAPVGAHVDLSVA ASGRLIAGLLDALDLSDVTLVANDTGGGIVLAALGNASLKWDRVSKLVFTNCDSFEHFPPKSFAPIVRLC ALSQSLGAIALKGLTTAPGLKVFTSAVTLNGVDAARRRAVFGGFLTSPAVRREAARFTADLKPSHTLAAV DALKRWDRPVLMAWGTSDKMFPLSHAERLAETFPNAVVRAIDNSSTYVMLDRPDETAQAIRAFVDPMKDV TR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1840 | - | - | 100% (283) | hydrolase, alpha/beta fold family protein, putative |
| M. avium 104 | MAV_2602 | - | 3e-74 | 50.38% (264) | putative hydrolase |
| M. avium 104 | MAV_5254 | - | 6e-39 | 36.67% (270) | hydrolase, alpha/beta hydrolase fold family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0079c | - | 3e-37 | 33.09% (269) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3236 | - | 2e-41 | 34.86% (284) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv0077c | - | 4e-37 | 33.09% (269) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0195c | - | 1e-40 | 36.19% (268) | putative hydrolase, alpha/beta hydrolase fold |
| M. marinum M | MMAR_0223 | - | 1e-38 | 34.93% (272) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_6763 | - | 6e-39 | 36.80% (269) | oxidoreductase |
| M. thermoresistible (build 8) | TH_3479 | - | 1e-98 | 63.00% (273) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_4891 | - | 8e-39 | 34.56% (272) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5859 | - | 3e-41 | 36.52% (282) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1840|M.avium_104 --MASIAVGDVEIDYVDAG--SGPVVVFVHGAYVTGLLWQDVVDRLSDS-
TH_3479|M.thermoresistible__bu MSATTITVDDAAIEYTDVG--GGPPIVFVHGAYVTGALWDDVVTRLSRG-
Mflv_3236|M.gilvum_PYR-GCK --MSTVGVPSGTIAYEDTGG-DGPVMVFGHGLLMDGRQWRKVLPQLPE--
Mvan_5859|M.vanbaalenii_PYR-1 --MFTADVPAGPIAYDDTGG-DGPVLVFGHGLLMDGRQWRKVIPRLPG--
MSMEG_6763|M.smegmatis_MC2_155 --MPVIELPSGPIAYEDTGG-DGPVLVFGHGLLMDGRQWRKVIPLLPG--
MAB_0195c|M.abscessus_ATCC_199 --MPTFESAAGPIQYRDSG--DGPPIVFVHGLFVTGTMWRKIVEPLSGR-
Mb0079c|M.bovis_AF2122/97 --MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRG
Rv0077c|M.tuberculosis_H37Rv --MSTIDISAGTIHYEATGPETGRPVVFVHGYMMGGQLWRRVSERLAGRG
MMAR_0223|M.marinum_M --MPTIDINAGTIHYEVTGPEHGRPVMFVHGYLMGGQLWRQVSERLAKRG
MUL_4891|M.ulcerans_Agy99 --MPTIDINAGTIHYEITGPEHGRPVMFVHGYLMGGQLWRQVSERLAEWG
* * * * ::* ** : * * : *.
MAV_1840|M.avium_104 HRCIAPTLPFGAQAAPVGAHVDLSVAASGRLIAGLLDALDLSDVTLVAND
TH_3479|M.thermoresistible__bu HRCIAPTWPFGAQRTPVGDSVDLDVVACGRRIIGLLEQLDLRDVTLVAND
Mflv_3236|M.gilvum_PYR-GCK YRCITPTLPMGAHTSPMRHDADLTETGMANILADFLDALDLDDVTLVLND
Mvan_5859|M.vanbaalenii_PYR-1 YRCITPTLPLGAHTVPMRDDADLTQTGVAGILADFLDALDLDDVTLVLND
MSMEG_6763|M.smegmatis_MC2_155 CRCITPTLPMGAHTAPMRPDADLTEQGVAGILADFLDALDLKDVTLVLND
MAB_0195c|M.abscessus_ATCC_199 FRCIAPDLPLGAHKTPMNPGVELGPRAVAGLVRDLIVNLDLDDVTVVATD
Mb0079c|M.bovis_AF2122/97 LRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGND
Rv0077c|M.tuberculosis_H37Rv LRCIAPTWPLGAHPKPLRPGADQTIGGVAGIVADVLAALELKDVVLVGND
MMAR_0223|M.marinum_M LRCFAPTWPLGAHPRALGPDADRSITGVGDLVADVLATLDLHDVVLVGND
MUL_4891|M.ulcerans_Agy99 LRCFAPTWPLGTHPRALGPDADRSITGVGDLVADVLATLDLHDVVLVGND
**::* *:*:: .: .: . . : ..: *:* **.:* .*
MAV_1840|M.avium_104 TGGGIVLAALGNASLKWDRVSKLVFTNCDSFEHFPPKSFAPIVRLCALSQ
TH_3479|M.thermoresistible__bu SGGGITLSALGILGLDWSRVSRLVFTNCDTFEHFPPKQFAPLVKLCRVAP
Mflv_3236|M.gilvum_PYR-GCK WGGG----QFMISEGRDKRIGRMVLASVTAFDNYPPEPARPAALLCRMPG
Mvan_5859|M.vanbaalenii_PYR-1 WGGG----QFVISEGRDKRIGRLVLVSCEAFDNFPPKPARPAALLCRFPG
MSMEG_6763|M.smegmatis_MC2_155 WGGG----QFLITDGRDARIGRLVLASCTAFDNYPPAPARPAAALCRLPG
MAB_0195c|M.abscessus_ATCC_199 TGGAI--TQLLLADGCD-RIGRVVLTPCDSFDNFLPKSIRIFQYWARVPG
Mb0079c|M.bovis_AF2122/97 TGGVV---TQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSAT
Rv0077c|M.tuberculosis_H37Rv TGGVV---TQLVAVHYPERLGALVLTSCDAFEHFPPPILKPVILAAKSAT
MMAR_0223|M.marinum_M TGGVV---AQLVAVRHPERLGALVLTSCDAFEHFPPPILKPVILAAKSKK
MUL_4891|M.ulcerans_Agy99 TGGVV---AQLVAVHHPERLGALVLTSCDAFEHFPPPILKPVILAAKSKK
** *:. :*:. :*::: * .
MAV_1840|M.avium_104 S--LGAIALKGLTTAPGLKVFTSAVTLNGVDAARRRAVFGGFLTSPAVRR
TH_3479|M.thermoresistible__bu P--LGGAVLRLLATGPGLAFFKRAVTRNGITGDRDDAIFGGFLSSAAVRR
Mflv_3236|M.gilvum_PYR-GCK GGWVLSRMLGTRFFRHSRRAYG-AMAKSGLPDELFDAWFAPAVENPAIRR
Mvan_5859|M.vanbaalenii_PYR-1 GGWVLSRMLGTRLFRHSRRAYG-ALAKSGIPDAMFDEWFRPAVESAAIRR
MSMEG_6763|M.smegmatis_MC2_155 GGRLLTKMFGTRFFRHSRLAYG-ALSKAGLPDGLFDEWFRPAVENAAVRR
MAB_0195c|M.abscessus_ATCC_199 TDFVLQPFK----LRLARRALGNTLAKHSIPDAVLGEWVAPLLAQQGIRR
Mb0079c|M.bovis_AF2122/97 LFRAAIQVMR----APAARNRAYAGLSHHNIDHLTRAWVRPALSNPAIAE
Rv0077c|M.tuberculosis_H37Rv LFRAAIQVMR----APAARNRAYAGLSHHNIDHLTRAWVRPALSNPAIAE
MMAR_0223|M.marinum_M MFRAAIQTMR----SPAARRRAYGDLAHADIDELAQRWVQPALSNPAIAE
MUL_4891|M.ulcerans_Agy99 MFRAAIQTMR----SPAARRRTYGDLAHADIDELAQRWVQPALSNPAIAE
. . : . .: .
MAV_1840|M.avium_104 EAARFTADLKPSH-TLAAVDALKRWDRPVLMAWGTSDKMFPLSHAERLAE
TH_3479|M.thermoresistible__bu EAVRFSAGLHPQH-TAAAAQAIGKWTKPVLVLWGTADDLFPVSHAQRLAE
Mflv_3236|M.gilvum_PYR-GCK DLVKFATGAPPRARLLEMSEQMRTFDRPVLVIWAREDRMMPLEHADRLVE
Mvan_5859|M.vanbaalenii_PYR-1 DLVKFATGSPSRRRLLELSENLATFDRPVLVVWAREDRMMPLQHADRLVE
MSMEG_6763|M.smegmatis_MC2_155 DLVKFATGAPPRRRLLELSERLRTFTRPVLVVWAREDRMMPLDHADRLVE
MAB_0195c|M.abscessus_ATCC_199 DVRAFLRGIDNRD-TLAAAEILRGFERPVLLLWPRTLPFFPFAHAERWLR
Mb0079c|M.bovis_AF2122/97 DLRQLSLSLRTEV-TTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA
Rv0077c|M.tuberculosis_H37Rv DLRQLSLSLRTEV-TTAVAARLPEFDKPALIAWSADDVFFALENGQRLAA
MMAR_0223|M.marinum_M DLRQLTLSLHTDV-TRGVAARLPEFSKPALIAWSADDKFFALEDGRRLAA
MUL_4891|M.ulcerans_Agy99 DLRQLTLSLHTDV-TRGVAARLPEFSKPALIAWSADDKFFALEDGRRLAA
: : . : : :*.*: * ::.. .. *
MAV_1840|M.avium_104 TFPNAVVRAIDNSSTYVMLDRPDETAQAIRAFVDPMKDVTR
TH_3479|M.thermoresistible__bu AFPNSRLRLIEGSSTYVMLDHPSETADAIGTFIAGRS----
Mflv_3236|M.gilvum_PYR-GCK LYPDATKIVVDDSWTLIPEDQPAAMAQALRDFVSLSPRES-
Mvan_5859|M.vanbaalenii_PYR-1 LFSDARKVVVDDSWTLIPEDQPEIMAQLLRDFVG-------
MSMEG_6763|M.smegmatis_MC2_155 LFPDATKVIVDDSWTLIPEDQPEVMAGALREFVG-------
MAB_0195c|M.abscessus_ATCC_199 LLPNAKLVEVPDSYTFVSEDQPELMVREIETFVGQRV----
Mb0079c|M.bovis_AF2122/97 TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT-----
Rv0077c|M.tuberculosis_H37Rv TIPRARFEVIEGARTFSMVDSPDRLADQLSTVAVRT-----
MMAR_0223|M.marinum_M TIPNARLELIEGARTFSMLDRPDRLADLLSAVAVRT-----
MUL_4891|M.ulcerans_Agy99 TIPNARLELIEGARTFSMLDRPDRLADLLSAVAVRT-----
. : : .: * * * . : .