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RRNIFEEIHDEFRATARSFFERECVPNVEKWERDGKVSREAWLAAGEHGLIGWEFDEKYGGLGVKDFRFN QIVSEEMFLTGSVGIGLGVQNDILVPYLNDLTTEEQKERWLPKFVSGEYIGSIAMSEPAAGSDLAGIKTT ARDEGDHWVVNGQKTFISNGLLSKLVLTAVKTDPSARHKGISLLMIEDGMEGFTRGRKLDKIGQYSADTA ELFFEDVKVPKENLVGELNRGFYHLVSNLPSERVGVACYALPAARRALDLTKTYASERTAFGQPIGKFQV NRHFLAEMQTKLDAAQTYLDQCVLSVNDGTLSDQDAAGLKWWTSEVQWEIIDRCLQLHGGYGYINEYEVA RLWRDSRVQRLYAGTTEIMKDLMGRAMGY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2561 | - | - | 100% (380) | long-chain specific acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1822 | - | 0.0 | 94.47% (380) | long-chain specific acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1883 | - | e-120 | 52.51% (379) | putative acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2743c | fadE20 | 1e-102 | 48.68% (378) | acyl-CoA dehydrogenase FADE20 |
| M. gilvum PYR-GCK | Mflv_2118 | - | 1e-121 | 53.03% (379) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv2724c | fadE20 | 1e-103 | 49.21% (378) | acyl-CoA dehydrogenase FADE20 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 2e-48 | 30.55% (383) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0065c | - | 1e-112 | 49.87% (381) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_1989 | fadE20 | 1e-107 | 50.79% (378) | acyl-CoA dehydrogenase FadE20 |
| M. smegmatis MC2 155 | MSMEG_5197 | - | 1e-119 | 52.51% (379) | long-chain specific acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4189 | - | 0.0 | 92.37% (380) | PUTATIVE isovaleryl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_3367 | fadE20 | 1e-104 | 50.00% (378) | acyl-CoA dehydrogenase FadE20 |
| M. vanbaalenii PYR-1 | Mvan_0906 | - | 1e-124 | 56.46% (379) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2561|M.avium_104 ---------MRRNIFEEIHDEFRATARSFFERECVPNVEKWERDGKVSRE
TH_4189|M.thermoresistible__bu ---------MRRNIFDEVHEDFRATARKFFERECVPNVEKWERDGKVSRE
Mb2743c|M.bovis_AF2122/97 ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVDRG
Rv2724c|M.tuberculosis_H37Rv ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRG
MMAR_1989|M.marinum_M ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVAPYHDEWEKAKIVDRG
MUL_3367|M.ulcerans_Agy99 ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVDRG
Mflv_2118|M.gilvum_PYR-GCK ---------MKRTIYDAEHEAFRDTVKEYIERELVPNSEKWETERIVDRS
MSMEG_5197|M.smegmatis_MC2_155 ---------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVDRS
Mvan_0906|M.vanbaalenii_PYR-1 ---------MRRTIFDTEHEQLRDTATQFIAREVAPNAQKWEEAGIVDRS
MAB_0065c|M.abscessus_ATCC_199 ---------MQRTIYTEDHEAFRESVKAFVQRHVDPRAETFIEQRYIDRE
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
*: :* : :. . .
MAV_2561|M.avium_104 AWLAAGEHGLIGWEFDEKYGGLGVKDFRFNQIVSEEMFLT-GSVGIGLGV
TH_4189|M.thermoresistible__bu AWLAAGEHGLIGWEFDEKYGGLGVKDFRFNQIISEEMFMT-GSVGIGLGI
Mb2743c|M.bovis_AF2122/97 VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAG-RYSGIGFGL
Rv2724c|M.tuberculosis_H37Rv VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAG-RYSGIGFGL
MMAR_1989|M.marinum_M VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAG-RYSGIGFGL
MUL_3367|M.ulcerans_Agy99 VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAG-RYSGIGFGL
Mflv_2118|M.gilvum_PYR-GCK AYTAAGKYGLIGFNMPEEFGGGGTDDFRFNAIIDEEIAKA-GVHGPALSL
MSMEG_5197|M.smegmatis_MC2_155 AYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKS-GVHGPALSL
Mvan_0906|M.vanbaalenii_PYR-1 AYTAAGRYGLIGFNMPEEYGGGGSDDFRFNAVVVEELAKF-GFLTPALSV
MAB_0065c|M.abscessus_ATCC_199 LWEEAGKQGYLGLDVPEEFGGSSAGDYRYNAVLQEELARSSAALASSMSI
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD--ASASLIPA
. * . . *::** . . :: * :
MAV_2561|M.avium_104 QNDILVPYLNDLTTEEQKERWLPKFVSGEYIGSIAMSEPAAGSDLAGIKT
TH_4189|M.thermoresistible__bu QNDILMPYLSSLTTEEQKERWLPKFISGEYIGSIAMSEPAAGSDLAGIKT
Mb2743c|M.bovis_AF2122/97 HNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGITT
Rv2724c|M.tuberculosis_H37Rv HNDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGITT
MMAR_1989|M.marinum_M HNDIVAPYLLALATEEQKQRWLPKFCTGEFITAIAMTEPGTGSDLQGIKT
MUL_3367|M.ulcerans_Agy99 HNEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIKT
Mflv_2118|M.gilvum_PYR-GCK HNDVVGPYFKDLTNDEQKKRWLPGVTSGETIIAVAMTEPGAGSDLAGIRT
MSMEG_5197|M.smegmatis_MC2_155 HNDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIRT
Mvan_0906|M.vanbaalenii_PYR-1 HNDIVGPYLKDLATREQQERWLPGYAAGELIGAIAMSEPGAGSDLAGIRT
MAB_0065c|M.abscessus_ATCC_199 HFDIVAPYLVELTTDEQKQRWLPKFCSGEMITAIGMTEPSGGSDLAALKT
MLBr_00737|M.leprae_Br4923 VNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRT
.: : . * :.: :* : : .::* *** .: *
MAV_2561|M.avium_104 TARDEGDHWVVNGQKTFISNGLLSKLVLTAVKTDPSARHKGISLLMIEDG
TH_4189|M.thermoresistible__bu TACDEGDHWVVNGQKTFISNGLLSKLVLTAVKTDPAAGHKGISLLMIEDG
Mb2743c|M.bovis_AF2122/97 RAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERG
Rv2724c|M.tuberculosis_H37Rv RAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERG
MMAR_1989|M.marinum_M RAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVERG
MUL_3367|M.ulcerans_Agy99 RAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVERG
Mflv_2118|M.gilvum_PYR-GCK SAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERD
MSMEG_5197|M.smegmatis_MC2_155 SAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERG
Mvan_0906|M.vanbaalenii_PYR-1 TAVRAGDDWILNGSKTFISAGINSDLVIVVARTDPDAGHKGFSLLVVERG
MAB_0065c|M.abscessus_ATCC_199 TAVKDGDDWVINGSKTFITNGARADLVVVAARTAPELKAKGITLFAVEEG
MLBr_00737|M.leprae_Br4923 RAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKD
* **.:::** * :*: * . . . * * :*:: : :. .
MAV_2561|M.avium_104 MEGFTRGRKLDKIGQYSADTAELFFEDVKVPKENLVGELNRGFYHLVSNL
TH_4189|M.thermoresistible__bu MEGFTRGRKLDKIGQLSADTAELFFDNVKVPKTNLVGELNRGFYHLVSNL
Mb2743c|M.bovis_AF2122/97 MAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNL
Rv2724c|M.tuberculosis_H37Rv MAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNL
MMAR_1989|M.marinum_M MEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQNL
MUL_3367|M.ulcerans_Agy99 MEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQNL
Mflv_2118|M.gilvum_PYR-GCK MEGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTNL
MSMEG_5197|M.smegmatis_MC2_155 MEGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLGKEGRGFYHLMTNL
Mvan_0906|M.vanbaalenii_PYR-1 MPGFERGRKLDKMGQPAQDTAELHFTDVRVPATNLLGEQNRGFYHLMANL
MAB_0065c|M.abscessus_ATCC_199 MPGFERGRKLDKVGQPEADTAELFFTDVRVPAENVIGEVNQGFISMMQRL
MLBr_00737|M.leprae_Br4923 DEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATL
** * : .*:* *:** * . :* .::*: . ** : *
MAV_2561|M.avium_104 PSERVGVACYALPAARRALDLTKTYASERTAFGQPIGKFQVNRHFLAEMQ
TH_4189|M.thermoresistible__bu PFERVGVACYALPAARRALDLTKAYALERTAFGQPIGKFQVNRHFIAEMQ
Mb2743c|M.bovis_AF2122/97 PQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELA
Rv2724c|M.tuberculosis_H37Rv PQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELA
MMAR_1989|M.marinum_M PQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAELA
MUL_3367|M.ulcerans_Agy99 PQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAELA
Mflv_2118|M.gilvum_PYR-GCK PSERLSIAISAIAGARAVFDETLQYSKDRKAFGQSIGSFQHNRFLLAEME
MSMEG_5197|M.smegmatis_MC2_155 PSERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLLAEME
Mvan_0906|M.vanbaalenii_PYR-1 PSERLSIAIAAVAGARETYRQTLQYAKDRTAFGQSIGSFQHNRFVLAELD
MAB_0065c|M.abscessus_ATCC_199 PQERMGCAVANIAHAVAVLEETVEYAKERKAFGQQIGSLQYNKFLIAELV
MLBr_00737|M.leprae_Br4923 DHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMA
* . . : * :*. **. *..:* :..:*::
MAV_2561|M.avium_104 TKLDAAQTYLDQCVLSVNDGTLSD-QDAAGLKWWTSEVQWEIIDRCLQLH
TH_4189|M.thermoresistible__bu VKLDAAQTYLDQCVLAVNEGTLSA-PDAAGLKWWTSEVQWEIIDRCLQLH
Mb2743c|M.bovis_AF2122/97 TEATVVRIMVDEFIKLHLAGKLTA-EQAAMAKWYATEKQVYLNDRCLQLH
Rv2724c|M.tuberculosis_H37Rv TEATVVRIMVDEFIKLHLAGKLTA-EQAAMAKWYATEKQVYLNDRCLQLH
MMAR_1989|M.marinum_M TEATMVRIMVDEFIELHLDGKLTA-EQAAMAKWYSTEKQVSLNDRCLQLH
MUL_3367|M.ulcerans_Agy99 TEATMVRIMVDESIELHLDGKLTA-EQAAMAKWYSTEKQVSLNDRCLQLH
Mflv_2118|M.gilvum_PYR-GCK TELEVTETYIDRCLQGVVDGELTA-VEAAKAKWWATEVAKKVVDQCVQLH
MSMEG_5197|M.smegmatis_MC2_155 TELEVTENYIDRCLQGVVDGELTA-VEAAKAKWWATETAKKIVDNCVQLH
Mvan_0906|M.vanbaalenii_PYR-1 TELDIAEQYVDRCLQALLDQDFSA-VDAAKAKWWCTELAKRVVDACLQLH
MAB_0065c|M.abscessus_ATCC_199 TKLEAAQVYVDQAVLAHSKGELTA-IDAAKAKWWSSQVQNEVIDACVQLH
MLBr_00737|M.leprae_Br4923 MKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLF
: .. : :* * : :: : .:**.
MAV_2561|M.avium_104 GGYGYINEYEVARLWRDSRVQRLYAGTTEIMKDLMGRAMGY
TH_4189|M.thermoresistible__bu GGYGYINEYEVARLWRDSRVQRLYAGTTEIMKDLMGRAMGF
Mb2743c|M.bovis_AF2122/97 GGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
Rv2724c|M.tuberculosis_H37Rv GGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
MMAR_1989|M.marinum_M GGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
MUL_3367|M.ulcerans_Agy99 GGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
Mflv_2118|M.gilvum_PYR-GCK GGYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV
MSMEG_5197|M.smegmatis_MC2_155 GGYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV
Mvan_0906|M.vanbaalenii_PYR-1 GGYGYMNEYKVAKDYVDTRIQTIYGGTTEIMKDIVGRSLGL
MAB_0065c|M.abscessus_ATCC_199 GGYGYMKEYRVARAWMDARVTKIWAGSNEIMKELIGRDLGF
MLBr_00737|M.leprae_Br4923 GGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
** ** :: * : * :: :: *:.:* : ::.* :