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VRRTIFDTEHEQLRDTATQFIAREVAPNAQKWEEAGIVDRSAYTAAGRYGLIGFNMPEEYGGGGSDDFRF NAVVVEELAKFGFLTPALSVHNDIVGPYLKDLATREQQERWLPGYAAGELIGAIAMSEPGAGSDLAGIRT TAVRAGDDWILNGSKTFISAGINSDLVIVVARTDPDAGHKGFSLLVVERGMPGFERGRKLDKMGQPAQDT AELHFTDVRVPATNLLGEQNRGFYHLMANLPSERLSIAIAAVAGARETYRQTLQYAKDRTAFGQSIGSFQ HNRFVLAELDTELDIAEQYVDRCLQALLDQDFSAVDAAKAKWWCTELAKRVVDACLQLHGGYGYMNEYKV AKDYVDTRIQTIYGGTTEIMKDIVGRSLGL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_0906 | - | - | 100% (380) | acyl-CoA dehydrogenase domain-containing protein |
M. vanbaalenii PYR-1 | Mvan_4587 | - | e-167 | 72.11% (380) | acyl-CoA dehydrogenase domain-containing protein |
M. vanbaalenii PYR-1 | Mvan_2439 | - | e-127 | 57.94% (378) | long-chain-acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2743c | fadE20 | 1e-126 | 58.84% (379) | acyl-CoA dehydrogenase FADE20 |
M. gilvum PYR-GCK | Mflv_2118 | - | 1e-166 | 71.58% (380) | acyl-CoA dehydrogenase domain-containing protein |
M. tuberculosis H37Rv | Rv2724c | fadE20 | 1e-127 | 59.37% (379) | acyl-CoA dehydrogenase FADE20 |
M. leprae Br4923 | MLBr_00737 | fadE25 | 1e-51 | 33.33% (372) | putative acyl-CoA dehydrogenase |
M. abscessus ATCC 19977 | MAB_3040c | - | 1e-126 | 57.03% (377) | acyl-CoA dehydrogenase |
M. marinum M | MMAR_1989 | fadE20 | 1e-127 | 58.58% (379) | acyl-CoA dehydrogenase FadE20 |
M. avium 104 | MAV_2600 | - | 1e-167 | 71.84% (380) | acyl-CoA dehydrogenase |
M. smegmatis MC2 155 | MSMEG_5197 | - | 1e-165 | 71.32% (380) | long-chain specific acyl-CoA dehydrogenase |
M. thermoresistible (build 8) | TH_4527 | - | 1e-169 | 72.63% (380) | PUTATIVE acyl-CoA dehydrogenase domain protein |
M. ulcerans Agy99 | MUL_3367 | fadE20 | 1e-124 | 57.78% (379) | acyl-CoA dehydrogenase FadE20 |
CLUSTAL 2.0.9 multiple sequence alignment Mb2743c|M.bovis_AF2122/97 ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVDRG Rv2724c|M.tuberculosis_H37Rv ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRG MMAR_1989|M.marinum_M ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVAPYHDEWEKAKIVDRG MUL_3367|M.ulcerans_Agy99 ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVDRG MAB_3040c|M.abscessus_ATCC_199 ---MAGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRA Mflv_2118|M.gilvum_PYR-GCK ---------MKRTIYDAEHEAFRDTVKEYIERELVPNSEKWETERIVDRS MSMEG_5197|M.smegmatis_MC2_155 ---------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVDRS TH_4527|M.thermoresistible__bu ---------MKRTVYEPEHEAFRETVREYIERELVPHAEKWETERIVDRS MAV_2600|M.avium_104 ---------MKRLVLEPEHEAFRETVRQFIERELVPNAERWEADRIVDRS Mvan_0906|M.vanbaalenii_PYR-1 ---------MRRTIFDTEHEQLRDTATQFIAREVAPNAQKWEEAGIVDRS MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE **: :* : :. : . . Mb2743c|M.bovis_AF2122/97 VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLH Rv2724c|M.tuberculosis_H37Rv VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYSGIGFGLH MMAR_1989|M.marinum_M VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFGLH MUL_3367|M.ulcerans_Agy99 VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYSGIGFGLH MAB_3040c|M.abscessus_ATCC_199 LWVEAGKQGFLGTDMPEEFGGGGLIDFRYNTIITEEVTKGRHTGVGFSLH Mflv_2118|M.gilvum_PYR-GCK AYTAAGKYGLIGFNMPEEFGGGGTDDFRFNAIIDEEIAKAGVHGPALSLH MSMEG_5197|M.smegmatis_MC2_155 AYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKSGVHGPALSLH TH_4527|M.thermoresistible__bu AYVAAGKYGLIGFNMPEKYGGGGTDDFRFNAVIDEEMAKAGVPGPALSLH MAV_2600|M.avium_104 AFVAAGKYGLIGFNMPEQYGGGGVDDFRFNAVIDEEIARYGGPSPSLSLQ Mvan_0906|M.vanbaalenii_PYR-1 AYTAAGRYGLIGFNMPEEYGGGGSDDFRFNAVVVEELAKFGFLTPALSVH MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQG-ADSVAACIVIEEVARVDASASLIPAV . *: . :**::** * * :: ** : Mb2743c|M.bovis_AF2122/97 NDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGITTR Rv2724c|M.tuberculosis_H37Rv NDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGITTR MMAR_1989|M.marinum_M NDIVAPYLLALATEEQKQRWLPKFCTGEFITAIAMTEPGTGSDLQGIKTR MUL_3367|M.ulcerans_Agy99 NEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIKTR MAB_3040c|M.abscessus_ATCC_199 NDVAGPYFRDLANDEQKARWFPGFCSGELISAIAMTEPGTGSDLQGIKTR Mflv_2118|M.gilvum_PYR-GCK NDVVGPYFKDLTNDEQKKRWLPGVTSGETIIAVAMTEPGAGSDLAGIRTS MSMEG_5197|M.smegmatis_MC2_155 NDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIRTS TH_4527|M.thermoresistible__bu NDVVAPYFNNLCTEEQKERWMPGIASGETIIAIAMTEPGAGSDLAGIRTS MAV_2600|M.avium_104 NDVVGPYFSSLANDEQKERWLPGIVSGELIVAVAMTEPGAGSDLAGIRTS Mvan_0906|M.vanbaalenii_PYR-1 NDIVGPYLKDLATREQQERWLPGYAAGELIGAIAMSEPGAGSDLAGIRTT MLBr_00737|M.leprae_Br4923 NKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTR *.: : . * : : :* : : *::* :*** .: * Mb2743c|M.bovis_AF2122/97 AVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERGM Rv2724c|M.tuberculosis_H37Rv AVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVERGM MMAR_1989|M.marinum_M AVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVERGM MUL_3367|M.ulcerans_Agy99 AVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVERGM MAB_3040c|M.abscessus_ATCC_199 AVKDGDHYILNGAKTFITNGINADLVIVVAQTDPEKGALGFSLIVVERGM Mflv_2118|M.gilvum_PYR-GCK AVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERDM MSMEG_5197|M.smegmatis_MC2_155 AVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVERGM TH_4527|M.thermoresistible__bu AVRDGDDWIINGSKTFISSGINCDLVVVVCRTDPEAGHKGFTLFVVERGM MAV_2600|M.avium_104 AVRDGDDWIINGAKTFISSGINCDLVVVVCRTDPEAGHKGFTLLVVEAGM Mvan_0906|M.vanbaalenii_PYR-1 AVRAGDDWILNGSKTFISAGINSDLVIVVARTDPDAGHKGFSLLVVERGM MLBr_00737|M.leprae_Br4923 AKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDD * **.:::** * :*: * :. *:. ***: * *:: ::*. . Mb2743c|M.bovis_AF2122/97 AGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNLP Rv2724c|M.tuberculosis_H37Rv AGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQNLP MMAR_1989|M.marinum_M EGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQNLP MUL_3367|M.ulcerans_Agy99 EGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQNLP MAB_3040c|M.abscessus_ATCC_199 EGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFIYLMKNLP Mflv_2118|M.gilvum_PYR-GCK EGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTNLP MSMEG_5197|M.smegmatis_MC2_155 EGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLGKEGRGFYHLMTNLP TH_4527|M.thermoresistible__bu EGFTRGRKLDKMGLHAQDTAELHFENVRVPHANLLGKEGHGFYHLMQNLP MAV_2600|M.avium_104 EGFSRGRKLEKMGLHYQDTAELAFENVRVPSANLLGKEGRGFYHLMHNLP Mvan_0906|M.vanbaalenii_PYR-1 PGFERGRKLDKMGQPAQDTAELHFTDVRVPATNLLGEQNRGFYHLMANLP MLBr_00737|M.leprae_Br4923 EGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLD ** * : .*:* . *:** * . :* .::*: . ** : .* Mb2743c|M.bovis_AF2122/97 QERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELAT Rv2724c|M.tuberculosis_H37Rv QERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAELAT MMAR_1989|M.marinum_M QERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAELAT MUL_3367|M.ulcerans_Agy99 QERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAELAT MAB_3040c|M.abscessus_ATCC_199 QERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFLLAELAT Mflv_2118|M.gilvum_PYR-GCK SERLSIAISAIAGARAVFDETLQYSKDRKAFGQSIGSFQHNRFLLAEMET MSMEG_5197|M.smegmatis_MC2_155 SERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLLAEMET TH_4527|M.thermoresistible__bu SERLSIAISAIAGARATWRETLQYAKDRKAFGKPIGSFQHNRFLLAEMDT MAV_2600|M.avium_104 SERLSIAISAIAGARETWRQTLQYAKDRKAFGQSIGSFQHNRFLLAEMDT Mvan_0906|M.vanbaalenii_PYR-1 SERLSIAIAAVAGARETYRQTLQYAKDRTAFGQSIGSFQHNRFVLAELDT MLBr_00737|M.leprae_Br4923 HTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAM * :*. * . . . :: * .:*. **..* .** :*:**:: Mb2743c|M.bovis_AF2122/97 EATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQLHG Rv2724c|M.tuberculosis_H37Rv EATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQLHG MMAR_1989|M.marinum_M EATMVRIMVDEFIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQLHG MUL_3367|M.ulcerans_Agy99 EATMVRIMVDESIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQLHG MAB_3040c|M.abscessus_ATCC_199 DATVIRVMVDEFISLLNKEE-LSVEQAAMAKWYSTEKQVHLIDRCLQLHG Mflv_2118|M.gilvum_PYR-GCK ELEVTETYIDRCLQGVVDGE-LTAVEAAKAKWWATEVAKKVVDQCVQLHG MSMEG_5197|M.smegmatis_MC2_155 ELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKIVDNCVQLHG TH_4527|M.thermoresistible__bu ELEVSEQYIDRCLQAVVDGE-LTAVEAAKAKWWCTEVAKKVVDQCVQLHG MAV_2600|M.avium_104 ELEIGEQYIDRCLRAVVDGE-LTAVEASKAKWWCTETAKKVIDGCVQLHG Mvan_0906|M.vanbaalenii_PYR-1 ELDIAEQYVDRCLQALLDQD-FSAVDAAKAKWWCTELAKRVVDACLQLHG MLBr_00737|M.leprae_Br4923 KVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLFG . . : . :: :* :.:: : .:**.* Mb2743c|M.bovis_AF2122/97 GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV Rv2724c|M.tuberculosis_H37Rv GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV MMAR_1989|M.marinum_M GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI MUL_3367|M.ulcerans_Agy99 GYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI MAB_3040c|M.abscessus_ATCC_199 GYGFMREYPVARAYMDSRIQTIYGGTTEIMKEIIGRSL-- Mflv_2118|M.gilvum_PYR-GCK GYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV MSMEG_5197|M.smegmatis_MC2_155 GYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV TH_4527|M.thermoresistible__bu GYGYMMEYRVARDFVDGRIQTIFGGTTEIMKEIIGRDLGL MAV_2600|M.avium_104 GYGYMTEYRVARDYMDNRIMTIFGGTTEIMKDIIGRDLGL Mvan_0906|M.vanbaalenii_PYR-1 GYGYMNEYKVAKDYVDTRIQTIYGGTTEIMKDIVGRSLGL MLBr_00737|M.leprae_Br4923 GAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR * *: :: * : * :: *: **.:* : ::.* *