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MSGWPFVGRDDELREAAEALRDSSRGVVLAGPSGVGKTALARALAGQLETEGYTIRYVLGTETGQAVPFG AFHHTLELSDAHEPTVMLAAAHHTLSADPNVLIVVDDAQYLDPLSALLVQQLAVHGSIKLIVTMRSGATT SDAVTALWKEHLLVRLDVEPFSRAQTAEVASTVLGGEVDEHAVAELHRYSSGSPMFLRGVLTAAMGDGVL VQAHGRWRLRGNLRPSPDLYELIASRVETLSAEELDVAEVVATADMLDWHVLLAICGPDAVARAERRGAI QVTSAGSHAVVQPGHPIIGEVVRSRCPVSRTRQINTLVAEHLSAQLRVATDASAVDVRTRIQLARFMTRA ESPPDTDLVTEAAASAVTMSDLVLGEQLARFAVEHGAGVNAALVLADAISWQGRGDEADALLARYPPDGE DDLTVTRWGCQRAANLFFVCGRPEPAWEVLAKTRDAVGSGKLTGLVTAMEVAFTYFSADMAGAAAAGSAA LATEMMPAATVWVALATAGALAKSGRFSEVAAVVRTGEHAASRCESGPHRYSLPLAEVLAGTLAGEFDDA QRACDRYAAASSDIPQADVMVTALAGRMKLARGQLEDACEQLQAAVWSMAAKLPPGWPMLVASWLAQAEG ARGNAEAAAVALTKAEAEVGPQVEVFAPELELARAWRAAAAGETSRAQHHAVLAAQNAHAAGMTAVELTA LHTSTRFGDRTVDARIQQLPTELDCPLGEAIALHSSGLAGHDGNRLVTAADRFERIGAMVLAGDAAAHAS REFGRRGERGNELEASTRAHWLASRCGAVTPALRCAADPLPLTPREWEIANLVSSGLSNRQVADRLCLSV RTVDGHLYRMFAKLGVADRDQLAKLIRFRPAT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2120 | - | - | 100% (872) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_4205 | - | e-132 | 35.37% (868) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5088 | - | 4e-52 | 27.39% (763) | TPR repeat-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1236c | - | 2e-69 | 35.27% (567) | hypothetical protein Mb1236c |
| M. gilvum PYR-GCK | Mflv_4479 | - | 1e-129 | 35.16% (856) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv1204c | - | 2e-69 | 35.27% (567) | hypothetical protein Rv1204c |
| M. leprae Br4923 | MLBr_01753 | - | 3e-13 | 22.55% (971) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3907c | - | 1e-133 | 35.48% (868) | LuxR transcriptional regulator |
| M. marinum M | MMAR_4234 | - | 1e-77 | 30.03% (786) | hypothetical protein MMAR_4234 |
| M. avium 104 | MAV_2364 | - | 0.0 | 49.30% (858) | TPR repeat-containing protein |
| M. thermoresistible (build 8) | TH_4413 | - | 5e-83 | 35.39% (664) | PUTATIVE putative response regulator receiver protein |
| M. ulcerans Agy99 | MUL_0955 | - | 7e-76 | 29.47% (777) | hypothetical protein MUL_0955 |
| M. vanbaalenii PYR-1 | Mvan_0243 | - | 0.0 | 56.39% (876) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2120|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0243|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4234|M.marinum_M --------------------------------------------------
MUL_0955|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MSMEG_2120|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0243|M.vanbaalenii_PYR-1 -------------------------------------------MTEKWTE
MAV_2364|M.avium_104 --------------------------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4234|M.marinum_M --------------------------------------------------
MUL_0955|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 --------------------MTTTTGTIDGRGQAPRLSPAKVHPDLHSYP
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
MSMEG_2120|M.smegmatis_MC2_155 MSGWPFVGRDDELREAAEALRDSS--RGVVLAGPSGVGKTALARALAGQL
Mvan_0243|M.vanbaalenii_PYR-1 LPDWPLVGRARELGRAIDALRPGSGFRGVVFVGEPGSGKTTLARAIAATL
MAV_2364|M.avium_104 ----------MEFRRSLAALNNGE-FHGVALVGDGGVGKSTLARMLAKTV
Mb1236c|M.bovis_AF2122/97 ----------MRVWKHVEAAVDSPDRCGVVLVGPHGVGKTLLAQLAAEQV
Rv1204c|M.tuberculosis_H37Rv ----------MRVWKHVEAAVDSPDRCGVVLVGPHGVGKTLLAQLAAEQV
MMAR_4234|M.marinum_M MPIRWNVPQHAAALEQLDVALSDLARPGAVILGPDGVGKSTLARLAAEHF
MUL_0955|M.ulcerans_Agy99 -------------MEQLDVALSDLARPGAVILGPDGVGKSTLARLAAEHF
Mflv_4479|M.gilvum_PYR-GCK -----MTAGLGLARTQVESAIVAS-RLRAVLVGAAGVGKTSMARKLARDY
MAB_3907c|M.abscessus_ATCC_199 MARSWQLLDRQTEFGAVRSAMADDSTCGAVLVGAAGVGKTTLARAVTKSL
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
MSMEG_2120|M.smegmatis_MC2_155 ETEGY----TIRYVLGTETGQAVPFGAFHHTLELS----DAHEPTVMLAA
Mvan_0243|M.vanbaalenii_PYR-1 RSEGV----TTRFVLGTDTGQAVPLGAFHRTLSIE----DPHEPAVMLAA
MAV_2364|M.avium_104 ESAGR----TVRFALGTQTGWAVPLGAFSRAVSLG----VGHEPAIMLAA
Mb1236c|M.bovis_AF2122/97 MSEDGR-SGRARWVVGTAPGRAIPFGAFRHLISLPASGADIGRPAALLRA
Rv1204c|M.tuberculosis_H37Rv MSEDGR-SGRARWVVGTAPGRAIPFGAFRHLISLPASGADIGRPAALLRA
MMAR_4234|M.marinum_M AQRHP--ATVIRWVTGTPTERTVPFGAFSHLVEI----AELGKPAALLRA
MUL_0955|M.ulcerans_Agy99 AQRHP--ATVIRWVTGTPTERAVPLGAFSHLVEI----AELGKPAALLRA
Mflv_4479|M.gilvum_PYR-GCK ARKHP--RLTSHWVSATASARDIPFAAFSHLIDV----SGGEEPTTLLRA
MAB_3907c|M.abscessus_ATCC_199 D-------ADVRWVACTESSRSIPLGVFAHWIQA----SGSRDPTALIAA
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSH-LLRDLARPVRVMQL
MSMEG_2120|M.smegmatis_MC2_155 AHHTLSA---DPNVLIVVDDAQYLDPLSALLVQQLAVHGSIKLIVTMRSG
Mvan_0243|M.vanbaalenii_PYR-1 AHRALAR---EHNLVLAIDDAHLLDPLSALLVQQAATSDTARLIVTIRSG
MAV_2364|M.avium_104 AHNTLGQ---DKNLVVVVDEAQLLDPLSATLVNQLAAGRSARLIVTIRSG
Mb1236c|M.bovis_AF2122/97 ARSSLTG--DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASE
Rv1204c|M.tuberculosis_H37Rv ARSSLTG--DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASE
MMAR_4234|M.marinum_M ARASLGRKVRQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAE
MUL_0955|M.ulcerans_Agy99 ARASLGRKVRQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAE
Mflv_4479|M.gilvum_PYR-GCK ARESLRS---AHGLLLVVDDAHHLDTLSATLVHQLAVTDNAHIMLTVREG
MAB_3907c|M.abscessus_ATCC_199 ARESIVS---TANPIIGIDDAHLLDDLSATLLHQIAVDHVGHVVATVRSG
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 CHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLL
MSMEG_2120|M.smegmatis_MC2_155 --------------------------------ATTSDAVTALWKEHLLVR
Mvan_0243|M.vanbaalenii_PYR-1 --------------------------------EVVPDAVTALWKEQLLMR
MAV_2364|M.avium_104 --------------------------------EPVLDAVTALLKERLLLT
Mb1236c|M.bovis_AF2122/97 --------------------------------AEPPDAIAALWSDDLLTR
Rv1204c|M.tuberculosis_H37Rv --------------------------------AEPPDAIAALWSDDLLTR
MMAR_4234|M.marinum_M --------------------------------VAP-EAIAALWTDNLLDR
MUL_0955|M.ulcerans_Agy99 --------------------------------VAP-EAIAALCTDNLLDR
Mflv_4479|M.gilvum_PYR-GCK --------------------------------EPVPDAVTALWKDSILSR
MAB_3907c|M.abscessus_ATCC_199 --------------------------------EPVPDAVTALWKDNYLQR
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 TLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDN
MSMEG_2120|M.smegmatis_MC2_155 LDVEPFSRAQTAEVASTVLGGEVDEHAVAELHRYSSGSPMFLRGVLTAAM
Mvan_0243|M.vanbaalenii_PYR-1 VDLNAFDRTQTQELVDAVLDGEVDSSVVDRLHDLAGGSPLVLRGLIGAAR
MAV_2364|M.avium_104 VHVDPFTREQTELLAGAVLGGPVDTRLVDELFERSAGNLLLLRGFLTAGV
Mb1236c|M.bovis_AF2122/97 VAIEPLDRAQTAAFVESALDATLDVADADELFRRSLGNPLYLRHLIDGGG
Rv1204c|M.tuberculosis_H37Rv VAIEPLDRAQTAAFVESALDATLDVADADELFRRSLGNPLYLRHLIDGGG
MMAR_4234|M.marinum_M IDVAPPD-------------------------------------------
MUL_0955|M.ulcerans_Agy99 IDVAPPD-------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK HDIAPFDRRESGLLLEQILGGTVEDVSTVRMFEISQGNPLYLRHLVDAAL
MAB_3907c|M.abscessus_ATCC_199 FELDPLTQRQSIALVEKVLGGPLEGLSADVMWRSSRGNPLFLRHLVEGSM
TH_4413|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LRRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPSLTILATSREPIGV
MSMEG_2120|M.smegmatis_MC2_155 GDGVLVQAHGRWRLRGNLRPSPDLYELIASRVETLSAEELDVAEVVATAD
Mvan_0243|M.vanbaalenii_PYR-1 EDGVLVRQGGRWRLHGRLRVGTDVHELVQTQLAGLTEGEFEVVEIVSAAE
MAV_2364|M.avium_104 ESGALVHTEQGWQLQGPLRGDRELHDALEYRLQSLSSEEREVVEVLATAE
Mb1236c|M.bovis_AF2122/97 ----LEHVDGRWRCRDEDRRP--LSGVIDEYLCALPEPARAVVDYLAIAE
Rv1204c|M.tuberculosis_H37Rv ----LEHVDGRWRCRDEDRRP--LSGVIDEYLCALPEPARAVVDYLAIAE
MMAR_4234|M.marinum_M ---------------GKTKQS--EPADVDEFIAELPAPARAVLDYLTVEE
MUL_0955|M.ulcerans_Agy99 ---------------GQTKQS--EPADVDEFIAELPAPARAVLDYLTVEE
Mflv_4479|M.gilvum_PYR-GCK GTGSLRQVEGVWQLRGEMTLSPQLTTLIDAHLTNLPEPVRSVLEFLAIDD
MAB_3907c|M.abscessus_ATCC_199 QAGSLTEVNGVWQLRGDAVVPSGLDTLIGDRLEHVDDTVFSALKVLSMCE
TH_4413|M.thermoresistible__bu -------------VVRRSGGAPGLIALIEERIGLLAEPVGDVVDILAVGE
MLBr_01753|M.leprae_Br4923 AGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLD
: . . . :
MSMEG_2120|M.smegmatis_MC2_155 MLDWHVLLAICG---PDAVARAE-RRGAIQVTSAGSHAVVQPGHPIIGEV
Mvan_0243|M.vanbaalenii_PYR-1 VLDWNVLRALCD---AEAIARTE-HRGVIEFVDDGSHTLVRAGHPILGEV
MAV_2364|M.avium_104 LLEWEILRDICD---ADAMASLE-RRGLIQLVTDGSHTLVQLNHPMLGEA
Mb1236c|M.bovis_AF2122/97 PLARTDLVALVGGEQLDTLGQAE-AAGAVRVGPDSDTSEIFVGHPLYADR
Rv1204c|M.tuberculosis_H37Rv PLARTDLVALVGGEQLDTLGQAE-AAGAVRVGPDSDTSEIFVGHPLYADR
MMAR_4234|M.marinum_M PLSLADLTVLAGEGAVQQAVELG-AAETRVRGEPDEPAVVYTAHPLFAKR
MUL_0955|M.ulcerans_Agy99 PLSLADLTVLAGEGAVQQAVELG-AAETRVRGEPDEPAVVYTAHPLFAKR
Mflv_4479|M.gilvum_PYR-GCK PLSVDDLAALTG---IDAVDAAE-TCGVVTITDRAGALYAHPFHPIYTER
MAB_3907c|M.abscessus_ATCC_199 PLDIDTLCEIAS---DEAVDAAE-IADLIRVERDGVRTVVRFSHPMFGEA
TH_4413|M.thermoresistible__bu PVDLGLLTRLTD---PAAVEEAD-VRGLIAIE-DGDRALVRLAHPLYGEV
MLBr_01753|M.leprae_Br4923 GMPLAIELAAARIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASM
: :.: .
MSMEG_2120|M.smegmatis_MC2_155 VRSRCPVSRTRQINTLVAEHLSAQLRVATDAS---AVDVRTRIQLARFMT
Mvan_0243|M.vanbaalenii_PYR-1 VRQRGGVARTRQLNTMLAQSISDFLGTDATHPYSVGADVRSRIQLARFMT
MAV_2364|M.avium_104 ATRHAGVVRSRQLNGILAKTLRKHLRAAGRRS--QISDPRGRIQLAQFIM
Mb1236c|M.bovis_AF2122/97 ARAVLTAEHAHALRVSLVAQLAKHP----------SDHVSDQLRLSSLAI
Rv1204c|M.tuberculosis_H37Rv ARAVLTAEHAHALRVSLVAQLAKHP----------SDHVSDQLRLSSLAI
MMAR_4234|M.marinum_M ARVALGDDGARQRRTELVTLLSQHP----------NEHLSDRLRLASLAL
MUL_0955|M.ulcerans_Agy99 ARVALGDDGARQRRTELVTLLSQHP----------NEHLSDRLRLASLAL
Mflv_4479|M.gilvum_PYR-GCK VRSSLGLLAMRRLRKLLAGRMSVRA----------PGNLSTRLRMAALAM
MAB_3907c|M.abscessus_ATCC_199 VRRRVGTASGRRLRGKLVRVLRDRD----------LGTASNRIRLARLSI
TH_4413|M.thermoresistible__bu RRRRAAVTRLRRLRGLVADELAQAAD---------ADDLAQVVRRTTLLL
MLBr_01753|M.leprae_Br4923 DWSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRLTM
. : :
MSMEG_2120|M.smegmatis_MC2_155 RAESPPD----------------TDLVTEAAASAVTMSDLVLGEQ-----
Mvan_0243|M.vanbaalenii_PYR-1 CSDAEPD----------------LELITAAAADAVTMSNLVLAEQ-----
MAV_2364|M.avium_104 RSDLEPD----------------LDVVIKAAADAMAMSNVVLGEQ-----
Mb1236c|M.bovis_AF2122/97 DVPASATPA-------------AVTDAATAAGQALRLGDVRLAER-----
Rv1204c|M.tuberculosis_H37Rv DVPASATPA-------------AVTDAATAAGQALRLGDVRLAER-----
MMAR_4234|M.marinum_M DTDALQP----------------VDDVVESAEQALRLGDLTLAER-----
MUL_0955|M.ulcerans_Agy99 DTDALQP----------------VDDVVESAEQALRLGDLTLAER-----
Mflv_4479|M.gilvum_PYR-GCK GTDEPPS----------------ADELVGLSWEAMRLGDLALGER-----
MAB_3907c|M.abscessus_ATCC_199 DCDEPVD----------------VDLLVTAAKDAVYLSNLPLGEE-----
TH_4413|M.thermoresistible__bu DSDRRPD----------------VDLFVRAARGAARIGDLPLAER-----
MLBr_01753|M.leprae_Br4923 LIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYM
:: *...
MSMEG_2120|M.smegmatis_MC2_155 LARFAVEHGAGVNAALVLADAISWQG-------RGDEADALLARYPPDGE
Mvan_0243|M.vanbaalenii_PYR-1 LARFAFDRGGGLPSAIALADAISWQG-------RGQEAEAILAAFDPDGA
MAV_2364|M.avium_104 LATFAVDRGGGLAAALVLAEAVSWQG-------RGEEADSILLGADVDDA
Mb1236c|M.bovis_AF2122/97 LARAALDRSDALAARLPLAYALGWQG-------RGREADAVLAAVNPAEL
Rv1204c|M.tuberculosis_H37Rv LARAALDRSDALAARLPLAYALGWQG-------RGREADAVLAAVNPAEL
MMAR_4234|M.marinum_M LAQAALDRSGGLQARLVLGQALAWRG-------RGREAGQVLTAVDPGQL
MUL_0955|M.ulcerans_Agy99 LAQAALDRSGGLQARLVLGQALAWRG-------RGREAGQVLTAVDPGQL
Mflv_4479|M.gilvum_PYR-GCK LARAALDQADGLAARLPLAHSLSWQG-------RGRDADDVLNPVDPDTL
MAB_3907c|M.abscessus_ATCC_199 LARAAVDGGGGLQAAAMLSRSLLWQG-------RPEQAEEILAAFDPDDL
TH_4413|M.thermoresistible__bu LSGAAVRAGATVEAAIVHARALTWLG-------RGDQAETVLAAIDVADH
MLBr_01753|M.leprae_Br4923 ALGALLDTPGDIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASS
. : . :: :
MSMEG_2120|M.smegmatis_MC2_155 DDLTVTRWGCQRAANLFFVCGRPEPAWEVLAKTRDAVGSGKLTGLVTAME
Mvan_0243|M.vanbaalenii_PYR-1 DALMTVRWGCLRGANLFFGCGHSDGAWAALATVRERVASEDLLSLVTAME
MAV_2364|M.avium_104 DEWLIARWGCLRAANLAWGCGDAEGATRVLAEVKQRLATEGSLQLIDALD
Mb1236c|M.bovis_AF2122/97 TETELMAWAIPRAANRFWMLNEPERATAFLQTTRSRVTEPTARSTLDALA
Rv1204c|M.tuberculosis_H37Rv TETELMAWAIPRAANRFWMLNEPERATAFLQTTRSRVTEPTARSTLDALA
MMAR_4234|M.marinum_M SEAELMAWAVPQAANQFWMLGEPERATAFLQTTRNRVTDLTARTTLDALT
MUL_0955|M.ulcerans_Agy99 SEAELMAWAVPQAANQFWMLGEPERATAFLQTTRNRVTDLTARTTLDALT
Mflv_4479|M.gilvum_PYR-GCK TQWDLMAWTLPKAANRFWMLSESEEAVEYLRQMRARITERGALHTIDALA
MAB_3907c|M.abscessus_ATCC_199 DELSLVLWGIPRISIAFWSMGENERAHELLALLHERVRHHILKPVVDATD
TH_4413|M.thermoresistible__bu T-----RLAFMRASNMLWALSDPEGAKRLIGQAAAGMP-ADQRAHLDAFC
MLBr_01753|M.leprae_Br4923 LQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAI
. : . : : :
MSMEG_2120|M.smegmatis_MC2_155 VAFTYFSA-----DMAGAAAAGSAALATEMMP-AATVWVALATAGALAKS
Mvan_0243|M.vanbaalenii_PYR-1 VSLAFFSG-----DVPVAVRLGQAALATERMP-MATVWAAMATAGALSLS
MAV_2364|M.avium_104 VSIGFFRG-----DIARTIELGPRLCEPDVVP-MATVWAAVATCGALTAV
Mb1236c|M.bovis_AF2122/97 ATFAMNSG-----NLPRAITLATEVLSGPAADDMAVAWAASAAALSSARM
Rv1204c|M.tuberculosis_H37Rv ATFAMNSG-----NLPRAITLATEVLSGPAADDMAVAWAASAAALSSARM
MMAR_4234|M.marinum_M ATFAMNSG-----NVPRAITLATEVLAEPSADDTAIAWAASAAALASARM
MUL_0955|M.ulcerans_Agy99 ATFAMNSG-----NVPRAITLATEVLAEPSADDTAIAWAASAAALASARM
Mflv_4479|M.gilvum_PYR-GCK ATFAMNAG-----DPAEAVTVAKGILAADDAQDLAVAWASAAATLSSARM
MAB_3907c|M.abscessus_ATCC_199 AAIALHEN-----RFDEGLARAHAVLSDPVAPKQAVEFAAFGVGLTLPVA
TH_4413|M.thermoresistible__bu AVHAAAMG-----QPDEVFRHAGAVVVDELPG-IIGAETAWALTLAAGEA
MLBr_01753|M.leprae_Br4923 LASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVAR
. . :
MSMEG_2120|M.smegmatis_MC2_155 GRFSEVAAVVRTGEH--AASRC-ESGPHRYSLP-LAEVLAGTLAGEFDDA
Mvan_0243|M.vanbaalenii_PYR-1 GRLDEVRPIARQGLQ--AARYC-ESGPQHYTIG-LAEVLAYTASGDMDAA
MAV_2364|M.avium_104 GRFSEVGRIAAAGVR--ATAQC-RAGAQRFAIG-LAEVMAATAAGDYPAA
Mb1236c|M.bovis_AF2122/97 GRFGDVDRLAERASA--AEHP----GLLRFTVG-LAQITSLLLAGDVAPA
Rv1204c|M.tuberculosis_H37Rv GRFGDVDRLAERASA--AEHP----GLLRFTVG-LAQITSLLLAGDVAPA
MMAR_4234|M.marinum_M GRFADVPQLAQRASE--AEHP----GLLRFTVG-LAQITTLLMAGEVAQA
MUL_0955|M.ulcerans_Agy99 GRFADVPQLAQRASE--AEHP----GLLRFTVG-LAQITTLLMAGEVAQA
Mflv_4479|M.gilvum_PYR-GCK GRFAEVDGLAQRGLD--AAHP----GLLRFTLG-LGQTLALIMNADVASA
MAB_3907c|M.abscessus_ATCC_199 GRGHEFEPIAQRCRD--DKKRT-TDGLIAAMVR-YCDVLALTYTGQLDLA
TH_4413|M.thermoresistible__bu GRTAEAVAAADTGYR--LTARFSDAAYTRFTLT-DAHVTALILAGRIAAA
MLBr_01753|M.leprae_Br4923 PYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAADDLA
: . . : . *
MSMEG_2120|M.smegmatis_MC2_155 QRACDRYAAASSD-IPQADVMVTALAGRMKLARGQLEDACEQLQAAVWSM
Mvan_0243|M.vanbaalenii_PYR-1 DHACERYSAMTCG-VPQAEAIVNALVGRVNFARGLLAAACDALSTSLWTM
MAV_2364|M.avium_104 ERIHKRYAALATG-LPAAEAMVDAMLGVLQLTRGELQEACATLDRSISQL
Mb1236c|M.bovis_AF2122/97 QELAKRFTDFA---------------------------------------
Rv1204c|M.tuberculosis_H37Rv QELAKRFTDFA---------------------------------------
MMAR_4234|M.marinum_M QELAQRFTDFAEL-QQPGRAIGEVLLAHVLIVKGEFGAAAAMLEPAAAEL
MUL_0955|M.ulcerans_Agy99 QELAQRFTDFAEL-QQPGRAIGEVLLAHVLIVKGEFGTAAAMVEPAAAEL
Mflv_4479|M.gilvum_PYR-GCK EHLARHYLSFSEF-QQPGRAIGEVLLGHTLLASGRFGDAVTLLRQAAAAL
MAB_3907c|M.abscessus_ATCC_199 EERVAEYTKFSSAGQFLAWAIARIMAGVVATQRGLFREAIEAFEQALAAQ
TH_4413|M.thermoresistible__bu VDTATVLDRQVGDLPGGTALLARGVAGRAALAAGRLDDAVAWLRDVVSVL
MLBr_01753|M.leprae_Br4923 QEIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRT
MSMEG_2120|M.smegmatis_MC2_155 A----AKLPPGWPMLVASWLAQ------------------------AEGA
Mvan_0243|M.vanbaalenii_PYR-1 S----ESLPSGWVMLVAAWLAQ------------------------AEAA
MAV_2364|M.avium_104 S----QGFPLPWQLVVGALQAQ------------------------AEGA
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4234|M.marinum_M E----RTG-YSWGPLSLMLLAT------------------------AIAQ
MUL_0955|M.ulcerans_Agy99 E----RTG-YSWGPLSLMLLAT------------------------AIAQ
Mflv_4479|M.gilvum_PYR-GCK T----YTG-YSWGPLALTGLAQ------------------------ALGQ
MAB_3907c|M.abscessus_ATCC_199 R----ADRPLPWQLPARLLLAR------------------------AYAA
TH_4413|M.thermoresistible__bu FSADTAGGFYGFGYRYQHPYAT------------------------ALAV
MLBr_01753|M.leprae_Br4923 FGLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALA
MSMEG_2120|M.smegmatis_MC2_155 RGNAEAAAVALTKAEAEVGPQVEVFAPELELARAWRAA----------AA
Mvan_0243|M.vanbaalenii_PYR-1 RGNADGAAAALARAEDANGPQVAVFVPELELARSWHRA----------CV
MAV_2364|M.avium_104 RGDSAAAAVALRRVEEAYGPHVAVFLPELELARAWERA----------AA
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4234|M.marinum_M QGNIAETAKALRRAETRHGTKSALFAPELSLARAWAKA----------TV
MUL_0955|M.ulcerans_Agy99 QGNIAETAKALRRAETRHGTKSALFAPELSLARAWAKA----------TV
Mflv_4479|M.gilvum_PYR-GCK QGRAADASAVLTRAEASHGMRSALYAPDLALARAWTLA----------AA
MAB_3907c|M.abscessus_ATCC_199 LGRAVDGERVLDEAREHSGPHVAIHMPQMMLAKAWLVA----------AR
TH_4413|M.thermoresistible__bu LGHTAAAATALATLDEREFPSWRYLDHERTIALAWLRA----------AQ
MLBr_01753|M.leprae_Br4923 MGDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRLAD
MSMEG_2120|M.smegmatis_MC2_155 GETSRAQHHAVLAAQNAHAAGMTAVELTALHTSTRFGDRTVDARIQQLPT
Mvan_0243|M.vanbaalenii_PYR-1 GQTTTARDHALRAAQTARVKGMWAVEMCALHTAVRFGDRSQSARLRQCAA
MAV_2364|M.avium_104 GDTAGAQTQAMQAAQTARKAGMHLVEMRARHAALRFGDRAQAARVDELAS
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4234|M.marinum_M RDQAGALFDTREAARAAERGKQSAVALCVWHDAVRLGDTRALAPVTRLAA
MUL_0955|M.ulcerans_Agy99 RDQAGALFDTREAARAAERGKQSAVALCVWHDAVRLGDTRALAPVTRLAA
Mflv_4479|M.gilvum_PYR-GCK RDLRGAVASARDAVHAAVQSGQDAVALRALQDCARLGDTHGLATAVRLSD
MAB_3907c|M.abscessus_ATCC_199 GSDRGAVDAARRAADAAHSAGQYALEAEALHHAARFGDRTVGRRIESLCT
TH_4413|M.thermoresistible__bu GAVSTSIQRLRAEAESARTAGRFAVELLCLQTAVQFGDRTCGPRLHQLED
MLBr_01753|M.leprae_Br4923 NSVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQASLG
MSMEG_2120|M.smegmatis_MC2_155 ELDCPLGEAIALHSSGLAGHDGNRLVTAADRFERIGAMVLAGDAAAHASR
Mvan_0243|M.vanbaalenii_PYR-1 QLDSPLAEAIAAHGIGLSDHDGDRLDAAADMFDRLGAAAMAADASAHAAR
MAV_2364|M.avium_104 ILNSPSAQAVAGHARGLAQHDGDLLDAAAHRFADLGALAFAADAAAQAAS
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4234|M.marinum_M EIDCKVGNIVVRHARALADNDAGALASVADELAAIGMHAAAADAAAQAER
MUL_0955|M.ulcerans_Agy99 EIDCKVGNIVVRHARALANNDAGALASVADELAAIGMHAAAADAAAQAER
Mflv_4479|M.gilvum_PYR-GCK RIGCVTGPLCVAHLRALAAGDGAALDAVSADLETAGLPAAAADAAAQATF
MAB_3907c|M.abscessus_ATCC_199 RVHGPLTGLYARHALAVAHSDITGLEAVSADFEAAGLLLSAADAAAQAVA
TH_4413|M.thermoresistible__bu RVDGPRVAVAARFADALHTGDGSGLRSIADEFEDMGDMVAAADAAAHAAI
MLBr_01753|M.leprae_Br4923 ISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESA
MSMEG_2120|M.smegmatis_MC2_155 EFGRRGERGNELEASTRAHWLASRCG-AVTPALRCAADP-------LPLT
Mvan_0243|M.vanbaalenii_PYR-1 EHARAGARVKELEATTRAHWLAGRNC-VRTPAVTAIEDP-------LPIT
MAV_2364|M.avium_104 EHARRGDRRKEVESSTWAHALAGQCG-SRTPALDAAARP-------LPFS
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4234|M.marinum_M AGGR----------------------------------------------
MUL_0955|M.ulcerans_Agy99 AGGR----------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK AHQRRGDRAGEVASRSRASRLSQVCGAPATPALEQVLNP-------MPLT
MAB_3907c|M.abscessus_ATCC_199 LRMRAGDRGKGSDAAARVLRMADRCGGVVTPAILAAAKP-------LPIS
TH_4413|M.thermoresistible__bu AHRRRGLRGSALACSAHAQGLAERCGGAHTPALRRAAED-------LPLT
MLBr_01753|M.leprae_Br4923 VAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLT
MSMEG_2120|M.smegmatis_MC2_155 PREWEIANLVSSGLSNRQVADRLCLSVRTVDGHLYRMFAKLGVADRDQLA
Mvan_0243|M.vanbaalenii_PYR-1 DREREIAVLVGESLTNREIAERLGVSVRTIDGHLYRIFAKLSIEDREQLA
MAV_2364|M.avium_104 GRERQIVNLVAAGLSNREIADRLVISVRTVEGHLYRLFTKLGINNRDQLI
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4234|M.marinum_M --------------------------------------------------
MUL_0955|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK GREREVAVMVSQGLTNKAIAQRLSVSVRTVEGHVYRACMKFGVPDRAALA
MAB_3907c|M.abscessus_ATCC_199 SREREIAVLIGEGLSDKDIATRLQLSVRTVEGHIYRARMKLDADDREEFA
TH_4413|M.thermoresistible__bu DREREIVLLLGAGLTNREIADTLTLSVRTVENHIYKSMLKTGTSSRDELA
MLBr_01753|M.leprae_Br4923 PAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLV
MSMEG_2120|M.smegmatis_MC2_155 KLIRFRPAT--------------
Mvan_0243|M.vanbaalenii_PYR-1 RLFRIRPAT--------------
MAV_2364|M.avium_104 QLIRRDAS---------------
Mb1236c|M.bovis_AF2122/97 -----------------------
Rv1204c|M.tuberculosis_H37Rv -----------------------
MMAR_4234|M.marinum_M -----------------------
MUL_0955|M.ulcerans_Agy99 -----------------------
Mflv_4479|M.gilvum_PYR-GCK STVGGMHGREGTA----------
MAB_3907c|M.abscessus_ATCC_199 KIVGSDLKPPEAS----------
TH_4413|M.thermoresistible__bu ALLPRSPRPSDPRRAPRSPRRID
MLBr_01753|M.leprae_Br4923 QEAARHN----------------