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HIDVMTIPQPLAQIGDLARRTQAAGFSGLLFTETGRTAYLNAAIASQAAPGLELSTGVAVAFPRSPFVTA ATAWELQEATGGKFRLGLGTQVRTHVVRRYGMAFERPGPRLRDYVLAVKACFSAFRTGTLDHHGEFYDLD FITPQWSAGPIDAPDPKVDVAAVNPWMLRMAGEVADGVHIHPLGELGYLTRHVVPNVAKGAAKAGRSPAD IAVIVPVMTIVGDSEEERAIERESVRASMAFYGSTPNYAFIWDEAGFEGTTARIREKQKAGDFPAMMAQI SDEHVDAFATESSWDGLADALTDKYGGIATRLVMYNALGDPGRFERYGEVARRMHG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1372 | - | - | 100% (337) | hypothetical protein MMAR_1372 |
| M. marinum M | MMAR_1390 | - | 1e-42 | 32.06% (315) | oxidoreductase |
| M. marinum M | MMAR_2980 | - | 2e-38 | 31.87% (320) | hypothetical protein MMAR_2980 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3214 | - | 1e-51 | 68.00% (150) | hypothetical protein Mb3214 |
| M. gilvum PYR-GCK | Mflv_5162 | - | 1e-164 | 81.79% (335) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3192 | - | 1e-51 | 68.00% (150) | hypothetical protein Rv3192 |
| M. leprae Br4923 | MLBr_00348 | - | 1e-09 | 25.32% (316) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3914c | - | 8e-49 | 35.53% (318) | oxidoreductase |
| M. avium 104 | MAV_2121 | - | 1e-171 | 84.78% (335) | hypothetical protein MAV_2121 |
| M. smegmatis MC2 155 | MSMEG_2256 | - | 1e-50 | 35.71% (308) | hypothetical protein MSMEG_2256 |
| M. thermoresistible (build 8) | TH_0425 | - | 1e-160 | 79.70% (335) | CONSERVED HYPOTHETICAL ALANINE AND PROLINE-RICH PROTEIN |
| M. ulcerans Agy99 | MUL_2504 | - | 0.0 | 98.22% (337) | hypothetical protein MUL_2504 |
| M. vanbaalenii PYR-1 | Mvan_1168 | - | 1e-166 | 82.99% (335) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3214|M.bovis_AF2122/97 ----------------MIPQPLSQLGDLARR---PGRRVLCSPKTA-APS
Rv3192|M.tuberculosis_H37Rv ----------------MIPQPLSQLGDLARR---PGRRVLCSPKTA-APS
MMAR_1372|M.marinum_M ----------MHIDVMTIPQPLAQIGDLARRTQAAGFSGLLFTETG-RTA
MUL_2504|M.ulcerans_Agy99 ----------MHIDVMTIPQPLAQIGDLARRTQAAGLSGLLFTETG-RTA
MAV_2121|M.avium_104 ----------MHVDAMTVPQPLGQIGDLARRTQSAGFSGLLFTETG-RTA
Mflv_5162|M.gilvum_PYR-GCK ----------MHVDVMTTPQPLRSTGDLARRTQGAGFDGMLFTETG-RTA
Mvan_1168|M.vanbaalenii_PYR-1 ----------MHVDVMTTPQPLQSTGELARRTQEVGFSGLLFTETG-RTA
TH_0425|M.thermoresistible__bu ----------VHVDVMVVPQPLGRVGDTARQVQRCGFSGLLLTETG-RTA
MAB_3914c|M.abscessus_ATCC_199 -----------MLIDVTLTTGLNTMAAEAAEAEESGYAGIWTFEGA-HDP
MSMEG_2256|M.smegmatis_MC2_155 ---MTDAQNPGVKVDRGISSRLSDVAQTARDLETAGCDGCWTGEIN-HDP
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDA
. . . * : .
Mb3214|M.bovis_AF2122/97 ISNATVASPAAPGLELSTGIALAFPRGPFVPAAAAWELQEATSGKFQLGL
Rv3192|M.tuberculosis_H37Rv ISNATVASPAAPGLELSTGIALAFPRGPFVPAAAAWELQEATSGKFQLGL
MMAR_1372|M.marinum_M YLNAAIASQAAPGLELSTGVAVAFPRSPFVTAATAWELQEATGGKFRLGL
MUL_2504|M.ulcerans_Agy99 YLNAAIASQAAPGLELSTGVAVAFPRSPFVTAATAWELQEATGGKFRLGL
MAV_2121|M.avium_104 YLNAAVASQAAPGLELSTGVAVAFPRSPFVTAAVAWELQEATKGRFRLGL
Mflv_5162|M.gilvum_PYR-GCK YLNVAAAALAAPGLQLSTGVAVAFPRSPFVTAASAWELQEASGGNFRLGL
Mvan_1168|M.vanbaalenii_PYR-1 YLSAAVAAHAAPGLELSTGVAVAFPRSPFVTAASAWELQEATGGKFRLGL
TH_0425|M.thermoresistible__bu YLNAAVASQAAPGLELSTGVAVAFPRSPFVTAAAAWELQEATGGKFRLGL
MAB_3914c|M.abscessus_ATCC_199 FLPLLLAAEHTKNVMLGTSIAVAFARNPMLLATIGWDLQAYSGGRFILGL
MSMEG_2256|M.smegmatis_MC2_155 FLPLALAAEHTRRIQIGTSIAVAFARNPMTVAHLGWDLQAYSGGRFILGL
MLBr_00348|M.leprae_Br4923 YTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGL
. : : :.*.:. .* * * . *: : *.. ***
Mb3214|M.bovis_AF2122/97 GTQVRKNVVHRYGMAFHRPGPRLR-YLLAVKACFAVFQTG---TPDHHGE
Rv3192|M.tuberculosis_H37Rv GTQVRKNVVHRYGMAFHRPGPRLR-YLLAVKACFAVFQTG---TPDHHGE
MMAR_1372|M.marinum_M GTQVRTHVVRRYGMAFERPGPRLRDYVLAVKACFSAFRTG---TLDHHGE
MUL_2504|M.ulcerans_Agy99 GTQVRTHVVRRYGMAFERPGPRLRDYVLAVKACFSAFRTG---TLDHHGE
MAV_2121|M.avium_104 GTQVRTHVVRRYGAAFERPGPRLRDYLLAVKACFAAFRSG---TLEHHGD
Mflv_5162|M.gilvum_PYR-GCK GTQVRTHVVRRYGVEFEHPGPRLRDYVLAVKACFGAFRTG---TLDHHGD
Mvan_1168|M.vanbaalenii_PYR-1 GTQVRTHVVRRYGADFEHPGPRLRDYVLAVKACFAAFRTG---KLDHHGQ
TH_0425|M.thermoresistible__bu GTQVRTHVVRRYGMPFDRPGPRLRDYVRAVKACFTAFRTG---TLDHHGE
MAB_3914c|M.abscessus_ATCC_199 GTQIKPHITRRFDMPWSSPAARMRDMVLAVRAIWQSWQERG--ALDYRGD
MSMEG_2256|M.smegmatis_MC2_155 GTQIRPHIEKRFSMPWSHPVRRMREYIAALQAIWTCWRDGT--SLRFEGE
MLBr_00348|M.leprae_Br4923 GVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLP
*.. : :. : * * * : :: : .
Mb3214|M.bovis_AF2122/97 FDNPDFITAQWSPARIDPP---GP------------------------SP
Rv3192|M.tuberculosis_H37Rv FDNPDFITAQWSPARIDPP---GP------------------------SP
MMAR_1372|M.marinum_M FYDLDFITPQWSAGPIDAP---DPKVDVAAVNPWMLRMAGEVADGVHIHP
MUL_2504|M.ulcerans_Agy99 FYDLDLITPQWSAGPIDAP---DPKVDIAAVNPWMLRMAGEVADGVHIHP
MAV_2121|M.avium_104 FYDLDFITPQWSPGPIDAP---DPKVDIAAVNPWMLRMAGEVADGVHVHP
Mflv_5162|M.gilvum_PYR-GCK FYNLDFITPQWSAGPIDAP---DPKVDVAAVNPWMLRMAGEVADGVHVHP
Mvan_1168|M.vanbaalenii_PYR-1 FYNLDFITPQWSAGPIDAP---DPKVDVAAVNPWMLRMAGEVADGVHVHP
TH_0425|M.thermoresistible__bu FYELDFITPQWSPGPIYAP---DPKVDVAAVNPWMLRMAGEVADGVHVHP
MAB_3914c|M.abscessus_ATCC_199 FYQNTLMTPMFMPDPAEVSAFGPPPIWLAGVGTGMTEVAGEVADGFMSHP
MSMEG_2256|M.smegmatis_MC2_155 FYTHKIMTPMFTPEPSPAP---FPKVFVAAVGERMTEMCGEAADGLLAHA
MLBr_00348|M.leprae_Br4923 LTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIF
: .
Mb3214|M.bovis_AF2122/97 AG----------PR------------------------------------
Rv3192|M.tuberculosis_H37Rv AG----------PR------------------------------------
MMAR_1372|M.marinum_M LGELGYLTRHVVPNVAKGAAKAGRSPADIAVIVPVMTIVGDSEEERAIER
MUL_2504|M.ulcerans_Agy99 LGELGYLTRHVVPNVAKGAAKAGRSPADIAVILPVMTIVGDSDEERAIER
MAV_2121|M.avium_104 IGEPGYLARHVLPTVAEGAAKAGRSPSDIAIIVPVMTIVGDSDEERDQQR
Mflv_5162|M.gilvum_PYR-GCK LGEPGYIARHVIPKVAEGAQKSGRSPSEIALIVPVMTVVGDTDEERHRER
Mvan_1168|M.vanbaalenii_PYR-1 LGEPGYIARHVIPKIAEGAQNSGRSPDDIAVIVPVMTIVGDTDEERHRER
TH_0425|M.thermoresistible__bu IGEPGYLTRHVLPNVAAGAARSQRSPDDIALIVPVLTVVGDTDEERHTER
MAB_3914c|M.abscessus_ATCC_199 FCTPDYLAQVTRPALGRGALKSGKALADIQIHHSPMIIIGRDDAELASAR
MSMEG_2256|M.smegmatis_MC2_155 FTTRRYLDEVTLPALQRGMDRTGRSRNDFEVSCPVFLVTGSDEHQMAEAA
MLBr_00348|M.leprae_Br4923 FSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVT---EDRAAAF
Mb3214|M.bovis_AF2122/97 --------------------------------------------------
Rv3192|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1372|M.marinum_M ESVRASMAFYG------STPNYAFIWDEAGFEGTTARIREKQKAGDFPAM
MUL_2504|M.ulcerans_Agy99 ESVRASMAFYG------STPNYAFIWDEAGFEGTTARIREKQKAGDFPAM
MAV_2121|M.avium_104 EAVRASMAFYG------STPNYAFIWDEAGFEGTTARIREKQKAGDYAGM
Mflv_5162|M.gilvum_PYR-GCK ELVRASMSFYG------STPNYAFIWDEAGFEGTTARIREKQKAGDIKGM
Mvan_1168|M.vanbaalenii_PYR-1 ELVRASMSFYG------STPNYSFIWDEAGFEGTTARIRERQKAGDVKGM
TH_0425|M.thermoresistible__bu ERARAALSFYG------STPNYAFIWDEAGFEGTTARIREKQKARDHAGM
MAB_3914c|M.abscessus_ATCC_199 AAVRKQLAFYG------STPAYWPILELHGRAEMGPELKERSKQGEWEAM
MSMEG_2256|M.smegmatis_MC2_155 VATRKQLAFYG------STPAYRKVLELHGWGDLHTELHRLSLAGEWDTM
MLBr_00348|M.leprae_Br4923 AGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKA
Mb3214|M.bovis_AF2122/97 --------------------------------------------------
Rv3192|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1372|M.marinum_M MAQISDEHVDAFATESS-WDGLADALTDKYGGIATRLVMYNALGDPGRFE
MUL_2504|M.ulcerans_Agy99 MAQISDEHIDAFATESS-WDGLADALTDKYGGIATRLVMYNALGDPGRFE
MAV_2121|M.avium_104 AAQVSDDHIAVFATEST-WDGLADALIEKYSGTATRLVMYNSAADPERFE
Mflv_5162|M.gilvum_PYR-GCK AAQITDEHIATFATEST-WDGLADALKAKYGGTATRIVLYNALANPERFE
Mvan_1168|M.vanbaalenii_PYR-1 AAQITDEHIAAFATEST-WDGLADALTAKYGGTATRVVLYNALADPERFE
TH_0425|M.thermoresistible__bu AAVITDEHLAVFTTEST-WDGLADALRARYGGVATRLVLYNAQNTPEQLE
MAB_3914c|M.abscessus_ATCC_199 AALVDDDFVDTAAVTVTDPGQGARELQERYGDLVHRLGFNTPYRPDRALL
MSMEG_2256|M.smegmatis_MC2_155 GTLIDDDVLDAFAVVAP-LDELADALRRRCEGAIDRVLPGFPAAVPPATV
MLBr_00348|M.leprae_Br4923 AEIIPNELVDSTMIVGD-VDYVCKQIAAWSAAGVTMMMVSASSVEQVRDL
Mb3214|M.bovis_AF2122/97 ----------------
Rv3192|M.tuberculosis_H37Rv ----------------
MMAR_1372|M.marinum_M RYGEVARRMHG-----
MUL_2504|M.ulcerans_Agy99 RYGEVARRMHG-----
MAV_2121|M.avium_104 RYGEVARRIQHAVSG-
Mflv_5162|M.gilvum_PYR-GCK RYGIVAQRLSNAQQA-
Mvan_1168|M.vanbaalenii_PYR-1 RYGDVAQRLQR-----
TH_0425|M.thermoresistible__bu RYGAVARQLSAD----
MAB_3914c|M.abscessus_ATCC_199 PELLAAFPTR------
MSMEG_2256|M.smegmatis_MC2_155 NAVLDEFRDRPPVTRL
MLBr_00348|M.leprae_Br4923 AGLF------------