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AGAEEAGISGLLGQAARAQDIGFDGIWSTDVDRDPFLPLAVAAMTTTNVQLGTGIAVAFARNPMTTAMAA NDLQEMSDGRFVLGLGTQIQAHIERRFSMPWSAPAERMSEYVNAIRAIWRSWRTGERLDFRGDHYQHTLM TPMFTPTPHPHGDPKIVISAVGPRMTRVAARDADGLLVHGFTTQRYLSEVTLPIVEEELRKVGRRRADFT ISYPGLIASGSTDEELTRAVSAVRRQIAFYGSTPAYRHVLELHGWHDLHTELHRLSKAGDWTTMTGLIDD EVLNTFAAVGEPTEAGAEVVTRFAGLVDRFTLLTPYPLGDEAAAAIVAGARAATARA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0341 | - | - | 100% (338) | hypothetical protein MSMEG_0341 |
| M. smegmatis MC2 155 | MSMEG_2256 | - | 5e-95 | 55.02% (309) | hypothetical protein MSMEG_2256 |
| M. smegmatis MC2 155 | MSMEG_2037 | - | 2e-77 | 48.72% (312) | hypothetical protein MSMEG_2037 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1395 | - | 1e-88 | 51.57% (318) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4326 | - | 7e-93 | 49.25% (333) | putative oxidoreductase |
| M. tuberculosis H37Rv | Rv1360 | - | 1e-88 | 51.57% (318) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 5e-19 | 25.94% (293) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3914c | - | 8e-80 | 49.36% (314) | oxidoreductase |
| M. marinum M | MMAR_1390 | - | 4e-75 | 44.86% (321) | oxidoreductase |
| M. avium 104 | MAV_4719 | - | 3e-68 | 43.65% (307) | hypothetical protein MAV_4719 |
| M. thermoresistible (build 8) | TH_1626 | - | 1e-100 | 53.78% (331) | PROBABLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_2486 | - | 4e-74 | 44.55% (321) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0358 | - | 1e-130 | 64.79% (338) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0341|M.smegmatis_MC2_155 -------------MAGAEEAGISGLLGQAARAQDIGFDGIWSTDVD-RDP
Mvan_0358|M.vanbaalenii_PYR-1 ---MYVDGNLGGSIDGTGGADLNVLAEQVGTAERIGYDGIWSTEVS-RDP
Mb1395|M.bovis_AF2122/97 ---MGG--ARRLKLDGSIPNQLARAADAAVALERNGFDGGWTAEAS-HDP
Rv1360|M.tuberculosis_H37Rv ---MGG--ARRLKLDGSIPNQLARAADAAVALERNGFDGGWTAEAS-HDP
Mflv_4326|M.gilvum_PYR-GCK -------------MDAAVVSQLSHVPAAARTLEQRGYDGCWTAEIN-HDP
TH_1626|M.thermoresistible__bu ---MGGGAVSGLKIDRGIPSQLDRVPDVARTLERQGYDGCWTGEIN-HDP
MAB_3914c|M.abscessus_ATCC_199 -----------MLIDVTLTTGLNTMAAEAAEAEESGYAGIWTFEGA-HDP
MMAR_1390|M.marinum_M -----------MRVFTALYG-LADAAERARELRDAGATGVATFEGP-HDV
MUL_2486|M.ulcerans_Agy99 -----------MRVFTALYG-LADAAERARELRDAGASGVATFEGP-HDV
MAV_4719|M.avium_104 -----------MKVQLQVDGSPVRAAASAAEIAATGADGLFTFEGQ-HDV
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDA
: . * . : : *
MSMEG_0341|M.smegmatis_MC2_155 FLPLAVAAMTTTNVQLGTGIAVAFARNPMTTAMAANDLQEMSDGRFVLGL
Mvan_0358|M.vanbaalenii_PYR-1 FLPLLLAADRSTSLQLGTGVAVAFARSPMTMATVANDLNTFSQGRFVLGL
Mb1395|M.bovis_AF2122/97 FLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGWDLQTYSKGRLILGL
Rv1360|M.tuberculosis_H37Rv FLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGWDLQTYSKGRLILGL
Mflv_4326|M.gilvum_PYR-GCK FLPLTLAAEHTERMELGTSIAVAFARNPMSVAQIGWDLQDYSEGRLLLGL
TH_1626|M.thermoresistible__bu FLPLLLAAEHTTRLEIGTSIAVAFARNPMTVANIGWDLQAYSRGRFVLGL
MAB_3914c|M.abscessus_ATCC_199 FLPLLLAAEHTKNVMLGTSIAVAFARNPMLLATIGWDLQAYSGGRFILGL
MMAR_1390|M.marinum_M FAPLTLAATVGG-LDLMTNVAIAFPRNPIHLAHQAYDHQLLSGGRFILGL
MUL_2486|M.ulcerans_Agy99 FAPLTLAATVGG-LDLMTNVAIAFPRNPIHLAHQAYDHQLLSGGRFILGL
MAV_4719|M.avium_104 FFPLLIAAEATG-CELMTNVAIAPPRSPMHLAYAAYDLQLYSGGRFRLGL
MLBr_00348|M.leprae_Br4923 YTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGL
: ** . : *.:. .*.* * . : * ** ***
MSMEG_0341|M.smegmatis_MC2_155 GTQIQAHIERRFSMPWSAPAERMSEYVNAIRAIWRSWR----TGERLDFR
Mvan_0358|M.vanbaalenii_PYR-1 GSQIQPHITRRFSMPWSAPADRMREYIHALQAIWHSWQ----TGDKLDFR
Mb1395|M.bovis_AF2122/97 GTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQ----DGTKLCFE
Rv1360|M.tuberculosis_H37Rv GTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQ----DGTKLCFE
Mflv_4326|M.gilvum_PYR-GCK GSQIKPHIEKRFSMPWGRPVARMREFVQALHEIWACWR----DGTRLNFE
TH_1626|M.thermoresistible__bu GTQIRPHVERRFSMPWSHPVRRMREFVTALREIWSCWR----DGTRLSFH
MAB_3914c|M.abscessus_ATCC_199 GTQIKPHITRRFDMPWSSPAARMRDMVLAVRAIWQSWQ----ERGALDYR
MMAR_1390|M.marinum_M GTQVRAQIENRFGAAFDHPVARMTELIAALRAIFAAWN----CGDRLNFR
MUL_2486|M.ulcerans_Agy99 GTQVRAQIENRFGAAFDHPVARMTELIAALRAIFAAWN----CGDRLNFR
MAV_4719|M.avium_104 GSQIKVHVEKRYGSKWEPPAARMAEAISAIKAIFAAWE----GRARLDFR
MLBr_00348|M.leprae_Br4923 GVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLP
* . : :. : * * : : :: ::
MSMEG_0341|M.smegmatis_MC2_155 GDHYQHTLMTPMFTPTP---HPHGDPKIVISAVGPRMTRVAARDADGLLV
Mvan_0358|M.vanbaalenii_PYR-1 GDHYQHTLMTPMFSPAA---NPFGPPPVMVAAVGPKMTTVAAEAADGLLV
Mb1395|M.bovis_AF2122/97 GEFYTHKIMTPMFTPEP---QPYPVPRVFIAAVGEAMTEMCGEVADGHLG
Rv1360|M.tuberculosis_H37Rv GEFYTHKIMTPMFTPEP---QPYPVPRVFIAAVGEAMTEMCGEVADGHLG
Mflv_4326|M.gilvum_PYR-GCK GEFYTHTLMTPMFVPQQ---HAYADPKVFVAAVGDRMTEMCGEVADGLLA
TH_1626|M.thermoresistible__bu GDFYSHTLMTPMFVPEP---QPHGDPRIFLAAVGPEMTRMCGEVADGLLA
MAB_3914c|M.abscessus_ATCC_199 GDFYQNTLMTPMFMPDPAEVSAFGPPPIWLAGVGTGMTEVAGEVADGFMS
MMAR_1390|M.marinum_M GQFYRHTLMTPTFNPGP---IPFGPPPIYVGALGPRLTRAVAQHADGLLV
MUL_2486|M.ulcerans_Agy99 GQFYRHTLMTPTSNPGP---IPFGPPPIYVGALGPRLTRAVAQHADGLLV
MAV_4719|M.avium_104 GEFYTHTIMAPTFDPGP---NPYGPPPVLLGALGPMMTRTAAEVADGLLV
MLBr_00348|M.leprae_Br4923 LTGAGATGLGKALKPIT--HPLRADIPIMLGAEGPKNVALAAEICDGWLP
. : * : :.. * . .. .** :
MSMEG_0341|M.smegmatis_MC2_155 HGFTTQRYLSEVTLPIVEEELRKVGRRRA--DFTISYPGLIASGSTDEEL
Mvan_0358|M.vanbaalenii_PYR-1 HGFTTARYLREVTLPTVEKGLVATGRTRG--DFTTSYPGLIATGAEERDF
Mb1395|M.bovis_AF2122/97 HPMVSKRYLTEVSVPALLRGLARSGRDRS--AFEVSCEVMVATGADDAEL
Rv1360|M.tuberculosis_H37Rv HPMVSKRYLTEVSVPALLRGLARSGRDRS--AFEVSCEVMVATGADDAEL
Mflv_4326|M.gilvum_PYR-GCK HAFSTQRYVREVTIPTLERGIARAGRTRA--DVVVSSPLFVVTGHDEQEL
TH_1626|M.thermoresistible__bu HAFTTRRYLDEVTLPALLDGMNRAGRRRG--DFEVSCPVFVVTGTTETEL
MAB_3914c|M.abscessus_ATCC_199 HPFCTPDYLAQVTRPALGRGALKSGKALA--DIQIHHSPMIIIGRDDAEL
MMAR_1390|M.marinum_M MPFGSKRFLHANTMPAVHEGLRAGGRQAG--EFTIIPEIIVSAGDTEADR
MUL_2486|M.ulcerans_Agy99 MPFGSKRFLHANTMPAVHEGLRAGGRQAG--DFTIIPEIIVSAGDTEADR
MAV_4719|M.avium_104 MPFNSARHFAERTLPAIGEGLRRSGRTLT--EFPIIAQAMVAVGRDEADL
MLBr_00348|M.leprae_Br4923 IFFSPR--MADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDR---
: . . : * . :
MSMEG_0341|M.smegmatis_MC2_155 TRAVSAVRRQIAFYG------STPAYRHVLELHGWHDLHTELHRLSKAGD
Mvan_0358|M.vanbaalenii_PYR-1 NEALARVRHQIAFYG------ATPAYRAVLELHGWSELHTELHRLSKAGD
Mb1395|M.bovis_AF2122/97 AAACTATRKQIAFYG------STPAYRKVLEQHGWGDLHPELHRLSKLGE
Rv1360|M.tuberculosis_H37Rv AAACTATRKQIAFYG------STPAYRKVLEQHGWGDLHPELHRLSKLGE
Mflv_4326|M.gilvum_PYR-GCK AANAVATRKQIAFYA------STPAYRGVLELHGWGDLQTELHRLSRAGE
TH_1626|M.thermoresistible__bu RANAVATRRQLAFYA------STPAYRSVLDLHGWGDLHTELHALSRRGE
MAB_3914c|M.abscessus_ATCC_199 ASARAAVRKQLAFYG------STPAYWPILELHGRAEMGPELKERSKQGE
MMAR_1390|M.marinum_M EQAAAGTRRLLAFYG------STPAYRPVLAAHGWEDLQPELNALSKQGR
MUL_2486|M.ulcerans_Agy99 EQAAAGTRRLLAFYG------STPAYRPVLAAHGWEGLQPELNALSKQGR
MAV_4719|M.avium_104 ATAIDGVASLIAFYG------STPAYLPVLQVEGWDGIQPELNALSKQGR
MLBr_00348|M.leprae_Br4923 AAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQ
:*:* .* : : * : *: : .
MSMEG_0341|M.smegmatis_MC2_155 WTTMTGLIDDEVLNTFAA-VGEPTEAGAEVVTRFAGLVDRFTLLTPYPLG
Mvan_0358|M.vanbaalenii_PYR-1 WDAMTGLIDDEVLGTFAV-VGEPKDVGRDIIRRFDGLIDRFTLYTPYPLD
Mb1395|M.bovis_AF2122/97 WEAMGGLIDDEMLGAFAV-VGPVDTIAGALRNRCEGVVDRVLPIFMAAS-
Rv1360|M.tuberculosis_H37Rv WEAMGGLIDDEMLGAFAV-VGPVDTIAGALRNRCEGVVDRVLPIFMAAS-
Mflv_4326|M.gilvum_PYR-GCK WDTMGALIDDTMLAEFAV-VAPVDELVHTIRARCDGLIDRVLVGFPPSID
TH_1626|M.thermoresistible__bu WDAMGERIDDDVLAAFAV-VAPLDELAGRLRERCAGVIDRVLPAFPAGVP
MAB_3914c|M.abscessus_ATCC_199 WEAMAALVDDDFVDTAAVTVTDPGQGARELQERYGDLVHRLGFNTPYRPD
MMAR_1390|M.marinum_M WQEMGALIDDTMMHTLAA-CGTPADVAAHIRDRVDGISDTVCLYQAAPIG
MUL_2486|M.ulcerans_Agy99 WQEMGALIDDTMMHTLAA-CGTPADVAARIRDRVDGISDTVCLYQAAPIG
MAV_4719|M.avium_104 FAQMRGLITDELVARIGI-VGTPEQCAEQIAARFGEHADEVCCYFPGYTP
MLBr_00348|M.leprae_Br4923 KDKAAEIIPNELVDSTMI-VGDVDYVCKQIAAWSAAGVTMMMVSASSVEQ
: : .: : .
MSMEG_0341|M.smegmatis_MC2_155 -DEAAAAIVAGARAATARA------------
Mvan_0358|M.vanbaalenii_PYR-1 -EATRAEIVEGIRCESRGA------------
Mb1395|M.bovis_AF2122/97 -QECINAALQDFRR-----------------
Rv1360|M.tuberculosis_H37Rv -QECINAALQDFRR-----------------
Mflv_4326|M.gilvum_PYR-GCK -EATVVGLVSELQAEETS-------------
TH_1626|M.thermoresistible__bu -ETAVTAVLHELRAAPSPTTSPVSTERSRHP
MAB_3914c|M.abscessus_ATCC_199 -RALLPELLAAFPTR----------------
MMAR_1390|M.marinum_M -LRTLAAIIDELR------------------
MUL_2486|M.ulcerans_Agy99 -LRTLAAIIDELR------------------
MAV_4719|M.avium_104 RPADVADLIGALHRVPALP------------
MLBr_00348|M.leprae_Br4923 -VRDLAGLF----------------------
.