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M. thermoresistible (build 8) TH_0425 ()

annotation: CONSERVED HYPOTHETICAL ALANINE AND PROLINE-RICH PROTEIN
coordinates: 931223 - 932239
length: 339

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0425-100% (339)CONSERVED HYPOTHETICAL ALANINE AND PROLINE-RICH PROTEIN
M. thermoresistible (build 8)TH_1626-6e-5236.28% (317) PROBABLE OXIDOREDUCTASE
M. thermoresistible (build 8)TH_3181-1e-4634.89% (321) PUTATIVE conserved hypothetical protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1395-1e-4935.71% (308) oxidoreductase
M. gilvum PYR-GCKMflv_5162-1e-15980.06% (336) luciferase family protein
M. tuberculosis H37RvRv1360-1e-4935.71% (308) oxidoreductase
M. leprae Br4923MLBr_00348-4e-1028.49% (179) putative coenzyme F420-dependent oxidoreductase
M. abscessus ATCC 19977MAB_3914c-1e-4533.75% (323) oxidoreductase
M. marinum MMMAR_1372-1e-16079.70% (335) hypothetical protein MMAR_1372
M. avium 104MAV_2121-1e-16179.70% (335) hypothetical protein MAV_2121
M. smegmatis MC2 155MSMEG_2256-4e-5036.51% (304) hypothetical protein MSMEG_2256
M. ulcerans Agy99MUL_2504-1e-15978.81% (335) hypothetical protein MUL_2504
M. vanbaalenii PYR-1Mvan_1168-1e-15980.30% (335) luciferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1395|M.bovis_AF2122/97            ---MGGARR--LKLDGSIPNQLARAADAAVALERNGFDGGWTAEAS-HDP
Rv1360|M.tuberculosis_H37Rv         ---MGGARR--LKLDGSIPNQLARAADAAVALERNGFDGGWTAEAS-HDP
MSMEG_2256|M.smegmatis_MC2_155      ---MTDAQNPGVKVDRGISSRLSDVAQTARDLETAGCDGCWTGEIN-HDP
MAB_3914c|M.abscessus_ATCC_199      -----------MLIDVTLTTGLNTMAAEAAEAEESGYAGIWTFEGA-HDP
MMAR_1372|M.marinum_M               ----------MHIDVMTIPQPLAQIGDLARRTQAAGFSGLLFTETG-RTA
MUL_2504|M.ulcerans_Agy99           ----------MHIDVMTIPQPLAQIGDLARRTQAAGLSGLLFTETG-RTA
MAV_2121|M.avium_104                ----------MHVDAMTVPQPLGQIGDLARRTQSAGFSGLLFTETG-RTA
Mflv_5162|M.gilvum_PYR-GCK          ----------MHVDVMTTPQPLRSTGDLARRTQGAGFDGMLFTETG-RTA
Mvan_1168|M.vanbaalenii_PYR-1       ----------MHVDVMTTPQPLQSTGELARRTQEVGFSGLLFTETG-RTA
TH_0425|M.thermoresistible__bu      ----------VHVDVMVVPQPLGRVGDTARQVQRCGFSGLLLTETG-RTA
MLBr_00348|M.leprae_Br4923          MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDA
                                                      .      .  .   :  *  .    *     .

Mb1395|M.bovis_AF2122/97            FLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGWDLQTYSKGRLILGL
Rv1360|M.tuberculosis_H37Rv         FLPLLLAAEHTSRLELGTNIAVAFARNPMIVANVGWDLQTYSKGRLILGL
MSMEG_2256|M.smegmatis_MC2_155      FLPLALAAEHTRRIQIGTSIAVAFARNPMTVAHLGWDLQAYSGGRFILGL
MAB_3914c|M.abscessus_ATCC_199      FLPLLLAAEHTKNVMLGTSIAVAFARNPMLLATIGWDLQAYSGGRFILGL
MMAR_1372|M.marinum_M               YLNAAIASQAAPGLELSTGVAVAFPRSPFVTAATAWELQEATGGKFRLGL
MUL_2504|M.ulcerans_Agy99           YLNAAIASQAAPGLELSTGVAVAFPRSPFVTAATAWELQEATGGKFRLGL
MAV_2121|M.avium_104                YLNAAVASQAAPGLELSTGVAVAFPRSPFVTAAVAWELQEATKGRFRLGL
Mflv_5162|M.gilvum_PYR-GCK          YLNVAAAALAAPGLQLSTGVAVAFPRSPFVTAASAWELQEASGGNFRLGL
Mvan_1168|M.vanbaalenii_PYR-1       YLSAAVAAHAAPGLELSTGVAVAFPRSPFVTAASAWELQEATGGKFRLGL
TH_0425|M.thermoresistible__bu      YLNAAVASQAAPGLELSTGVAVAFPRSPFVTAAAAWELQEATGGKFRLGL
MLBr_00348|M.leprae_Br4923          YTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGL
                                    :      .  :  : :.*.:.   .*.*   *  .  *:  : *.  ***

Mb1395|M.bovis_AF2122/97            GTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQDGTKLCFEGEFY
Rv1360|M.tuberculosis_H37Rv         GTQIRPHIEKRFSMPWGHPARRMREFVAALRAIWLAWQDGTKLCFEGEFY
MSMEG_2256|M.smegmatis_MC2_155      GTQIRPHIEKRFSMPWSHPVRRMREYIAALQAIWTCWRDGTSLRFEGEFY
MAB_3914c|M.abscessus_ATCC_199      GTQIKPHITRRFDMPWSSPAARMRDMVLAVRAIWQSWQERGALDYRGDFY
MMAR_1372|M.marinum_M               GTQVRTHVVRRYGMAFERPGPRLRDYVLAVKACFSAFRTG-TLDHHGEFY
MUL_2504|M.ulcerans_Agy99           GTQVRTHVVRRYGMAFERPGPRLRDYVLAVKACFSAFRTG-TLDHHGEFY
MAV_2121|M.avium_104                GTQVRTHVVRRYGAAFERPGPRLRDYLLAVKACFAAFRSG-TLEHHGDFY
Mflv_5162|M.gilvum_PYR-GCK          GTQVRTHVVRRYGVEFEHPGPRLRDYVLAVKACFGAFRTG-TLDHHGDFY
Mvan_1168|M.vanbaalenii_PYR-1       GTQVRTHVVRRYGADFEHPGPRLRDYVLAVKACFAAFRTG-KLDHHGQFY
TH_0425|M.thermoresistible__bu      GTQVRTHVVRRYGMPFDRPGPRLRDYVRAVKACFTAFRTG-TLDHHGEFY
MLBr_00348|M.leprae_Br4923          GVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAR---EAPVVSDGQHY
                                    *..    :   :.  :  *  * *: :  ::  :        :   *:.*

Mb1395|M.bovis_AF2122/97            THKIMTPMFT-----PEP---QPYPVPRVFIAAVGEAMTEMCGEVADGHL
Rv1360|M.tuberculosis_H37Rv         THKIMTPMFT-----PEP---QPYPVPRVFIAAVGEAMTEMCGEVADGHL
MSMEG_2256|M.smegmatis_MC2_155      THKIMTPMFT-----PEP---SPAPFPKVFVAAVGERMTEMCGEAADGLL
MAB_3914c|M.abscessus_ATCC_199      QNTLMTPMFM-----PDPAEVSAFGPPPIWLAGVGTGMTEVAGEVADGFM
MMAR_1372|M.marinum_M               DLDFITPQWS-----AGP---IDAPDPKVDVAAVNPWMLRMAGEVADGVH
MUL_2504|M.ulcerans_Agy99           DLDLITPQWS-----AGP---IDAPDPKVDIAAVNPWMLRMAGEVADGVH
MAV_2121|M.avium_104                DLDFITPQWS-----PGP---IDAPDPKVDIAAVNPWMLRMAGEVADGVH
Mflv_5162|M.gilvum_PYR-GCK          NLDFITPQWS-----AGP---IDAPDPKVDVAAVNPWMLRMAGEVADGVH
Mvan_1168|M.vanbaalenii_PYR-1       NLDFITPQWS-----AGP---IDAPDPKVDVAAVNPWMLRMAGEVADGVH
TH_0425|M.thermoresistible__bu      ELDFITPQWS-----PGP---IYAPDPKVDVAAVNPWMLRMAGEVADGVH
MLBr_00348|M.leprae_Br4923          PLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWL
                                       :  .          *          : :.. .     :..* .**  

Mb1395|M.bovis_AF2122/97            GHPMVSKRYLTEVSVPALLRGLARSG--RDRSAFEVSCEVMVATGADDAE
Rv1360|M.tuberculosis_H37Rv         GHPMVSKRYLTEVSVPALLRGLARSG--RDRSAFEVSCEVMVATGADDAE
MSMEG_2256|M.smegmatis_MC2_155      AHAFTTRRYLDEVTLPALQRGMDRTG--RSRNDFEVSCPVFLVTGSDEHQ
MAB_3914c|M.abscessus_ATCC_199      SHPFCTPDYLAQVTRPALGRGALKSG--KALADIQIHHSPMIIIGRDDAE
MMAR_1372|M.marinum_M               IHPLGELGYLTRHVVPNVAKGAAKAG--RSPADIAVIVPVMTIVGDSEEE
MUL_2504|M.ulcerans_Agy99           IHPLGELGYLTRHVVPNVAKGAAKAG--RSPADIAVILPVMTIVGDSDEE
MAV_2121|M.avium_104                VHPIGEPGYLARHVLPTVAEGAAKAG--RSPSDIAIIVPVMTIVGDSDEE
Mflv_5162|M.gilvum_PYR-GCK          VHPLGEPGYIARHVIPKVAEGAQKSG--RSPSEIALIVPVMTVVGDTDEE
Mvan_1168|M.vanbaalenii_PYR-1       VHPLGEPGYIARHVIPKIAEGAQNSG--RSPDDIAVIVPVMTIVGDTDEE
TH_0425|M.thermoresistible__bu      VHPIGEPGYLTRHVLPNVAAGAARSQ--RSPDDIALIVPVLTVVGDTDEE
MLBr_00348|M.leprae_Br4923          PIFFSPR--MADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDR--
                                       :     :       :  *  .:   :    : :              

Mb1395|M.bovis_AF2122/97            LAAACTATRKQIAFYG------STPAYRKVLEQHGWGDLHPELHRLSKLG
Rv1360|M.tuberculosis_H37Rv         LAAACTATRKQIAFYG------STPAYRKVLEQHGWGDLHPELHRLSKLG
MSMEG_2256|M.smegmatis_MC2_155      MAEAAVATRKQLAFYG------STPAYRKVLELHGWGDLHTELHRLSLAG
MAB_3914c|M.abscessus_ATCC_199      LASARAAVRKQLAFYG------STPAYWPILELHGRAEMGPELKERSKQG
MMAR_1372|M.marinum_M               RAIERESVRASMAFYG------STPNYAFIWDEAGFEGTTARIREKQKAG
MUL_2504|M.ulcerans_Agy99           RAIERESVRASMAFYG------STPNYAFIWDEAGFEGTTARIREKQKAG
MAV_2121|M.avium_104                RDQQREAVRASMAFYG------STPNYAFIWDEAGFEGTTARIREKQKAG
Mflv_5162|M.gilvum_PYR-GCK          RHRERELVRASMSFYG------STPNYAFIWDEAGFEGTTARIREKQKAG
Mvan_1168|M.vanbaalenii_PYR-1       RHRERELVRASMSFYG------STPNYSFIWDEAGFEGTTARIRERQKAG
TH_0425|M.thermoresistible__bu      RHTERERARAALSFYG------STPNYAFIWDEAGFEGTTARIREKQKAR
MLBr_00348|M.leprae_Br4923          -AAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSN
                                            :  :::*       .*  :  :    *      .:       

Mb1395|M.bovis_AF2122/97            EWEAMGGLIDDEMLGAFAVVGP-VDTIAGALRNRCEGVVDRVLPIFMAAS
Rv1360|M.tuberculosis_H37Rv         EWEAMGGLIDDEMLGAFAVVGP-VDTIAGALRNRCEGVVDRVLPIFMAAS
MSMEG_2256|M.smegmatis_MC2_155      EWDTMGTLIDDDVLDAFAVVAP-LDELADALRRRCEGAIDRVLPGFPAAV
MAB_3914c|M.abscessus_ATCC_199      EWEAMAALVDDDFVDTAAVTVTDPGQGARELQERYGDLVHRLGFNTPYRP
MMAR_1372|M.marinum_M               DFPAMMAQISDEHVDAFATESS-WDGLADALTDKYGGIATRLVMYNALGD
MUL_2504|M.ulcerans_Agy99           DFPAMMAQISDEHIDAFATESS-WDGLADALTDKYGGIATRLVMYNALGD
MAV_2121|M.avium_104                DYAGMAAQVSDDHIAVFATEST-WDGLADALIEKYSGTATRLVMYNSAAD
Mflv_5162|M.gilvum_PYR-GCK          DIKGMAAQITDEHIATFATEST-WDGLADALKAKYGGTATRIVLYNALAN
Mvan_1168|M.vanbaalenii_PYR-1       DVKGMAAQITDEHIAAFATEST-WDGLADALTAKYGGTATRVVLYNALAD
TH_0425|M.thermoresistible__bu      DHAGMAAVITDEHLAVFTTEST-WDGLADALRARYGGVATRLVLYNAQNT
MLBr_00348|M.leprae_Br4923          QKDKAAEIIPNELVDSTMIVGD-VDYVCKQIAAWSAAGVTMMMVSASSVE
                                    :       : :: :          .  .  :          :        

Mb1395|M.bovis_AF2122/97            -QECINAALQDFRR-------
Rv1360|M.tuberculosis_H37Rv         -QECINAALQDFRR-------
MSMEG_2256|M.smegmatis_MC2_155      PPATVNAVLDEFRDRPPVTRL
MAB_3914c|M.abscessus_ATCC_199      DRALLPELLAAFPTR------
MMAR_1372|M.marinum_M               PGRFERYGEVARRMHG-----
MUL_2504|M.ulcerans_Agy99           PGRFERYGEVARRMHG-----
MAV_2121|M.avium_104                PERFERYGEVARRIQHAVSG-
Mflv_5162|M.gilvum_PYR-GCK          PERFERYGIVAQRLSNAQQA-
Mvan_1168|M.vanbaalenii_PYR-1       PERFERYGDVAQRLQR-----
TH_0425|M.thermoresistible__bu      PEQLERYGAVARQLSAD----
MLBr_00348|M.leprae_Br4923          QVRDLAGLF------------