For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NTMCAYCGVGCGMVLQITTDPQTGRRHVAKSVGNKEHPANFGRLCTKGATTADLLAAPGRMDSAHARAGR GEPLEPIGTDQAITRCAKQLRAIIDEHGPDAFAMYVSGQMSLEAQYLANKLTKGFIGTNQIESNSRLCMA SAGSGYKLSLGADGPPGSYQDFEHADVFFVIGANMADCHPILFLRMMDRVKAGAKLIVVDPRRTATAEKA DLFLQIAPGTDLALLNGLLHLIVENGHTDGEFIAEFTEGWEVMPSFLEQYTPDRVSEITGIPEQDIRAAA QLIGEADNFMSCWTMGLNQSTHGTWNTNAICNLHLATGAICKPGSGPFSLTGQPNAMGGREMGYMGPGLP GQRSVASAADREFVEDVWGVPRGRLRTEVGTGTIDMFSRMADGQIKACWIICTNPVASVANRKTVLAGLE RAELVIAQDAYLGTETSEYADVLLPAALWAETEGVMVNSERNITLSQPAVAAPGGAMPDWQIIARIACEM GFSEAFSYSCAEEVFEEIKRFWNPTTGYDLRGVSYERLRRQPLQWPCPPQSTADRNPIRYLNDGVSQTQL VREDGTVPRLAFPTPSGRAVFFARPHLQPEEMPDDDYPFLLNTGRLPHQWHTMTKTGKVAKLNKLNPGPF VEIHPDDAARLGIGEHDRVEIASRRGRAVLPAVVSDRVRPGNCFAPFHWNDAFGEYLSINAVTNDAVDPI SNQPEFKACAVTLTKVAVSHPDSAIGTGPSAGHDTPESAPTEVREISVSQVDALGELLGVATSFKPEFNE LGRSYLAGMLTGLRSDVGRRAGGVPTLPPSAPFDSRTRLWVDGLLAGLFSRADASQQAALPEPPQPAAQQ PPAAPAGATPAPERAPVVVLWASQTGNAEELAADVAAQLAAAELPVALHSMDDFPAAELAATRELLLITS TTGDGDAPDNGSGLWRALTGDAAPRLGNTRYAVLALGDSNYDDFCGHGRKLDARLAELGATRIAERVDCE PDYEQAAAKWVADVIEALTRTPTAVGGDGGATVSARTSPVAAPSRPNTPAPHTYSKKHPLITDMVRNTTL NGPKSTKDVRHLVFNLPEDAVSYEAGDALGVWPRNSDELVDEWLAVTGLDGQTPVEVGEHGLMSLRSALT ERIEIAHISRDLVRFVQERTGDAKLAELLKPENKRALADWTWGRQSIDLLAQLPVSASAHEWLRVLKRLQ PRLYSISSSPKACPGEVHLTVSPVRYNFQGVPRRGVCSTYLAARSPGDRVAVYLQPSSNFRPPSDPDTPM IMIGPGTGIAPFRGFLQERRALGHRGPNWLFFGEQHAATDFYYRDELEQMREDGFLTELDLAFSRDQQHK VYVQHLMRNRGKQLWSWLQDGAQLYVCGTADPMAKDVDRALCDIAAEFGNLDPDAAKAYVQSLSADKRYH RDVY*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_2075 | - | - | 100% (1405) | FdhF protein |
M. avium 104 | MAV_4535 | - | e-99 | 34.06% (731) | nitrate reductase NarB |
M. avium 104 | MAV_4983 | - | 1e-25 | 25.65% (499) | molybdopterin oxidoreductase Fe4S4 subunit |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2924c | fdhF | 1e-28 | 28.03% (396) | formate dehydrogenase H |
M. gilvum PYR-GCK | Mflv_3016 | - | 0.0 | 55.62% (1406) | molybdopterin oxidoreductase |
M. tuberculosis H37Rv | Rv2900c | fdhF | 1e-28 | 28.03% (396) | formate dehydrogenase H |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2438 | - | 0.0 | 70.11% (696) | oxidoreductase |
M. marinum M | MMAR_3639 | fdhF | 0.0 | 74.43% (1412) | formate dehydrogenase H FdhF |
M. smegmatis MC2 155 | MSMEG_0161 | - | 3e-98 | 32.69% (731) | formate dehydrogenase, alpha subunit |
M. thermoresistible (build 8) | TH_4553 | - | 2e-54 | 60.11% (178) | PUTATIVE sulfite reductase (NADPH) alpha subunit |
M. ulcerans Agy99 | MUL_1474 | fdhF | 0.0 | 74.22% (1412) | formate dehydrogenase H FdhF |
M. vanbaalenii PYR-1 | Mvan_3491 | - | 0.0 | 56.89% (1408) | molybdopterin oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_3639|M.marinum_M -------------------------------------------------- MUL_1474|M.ulcerans_Agy99 -------------------------------------------------- MAV_2075|M.avium_104 -------------------------------------------------- Mflv_3016|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3491|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 MTLLSEPDFGTPAKPGPATVTVEVDGIPVSVPEGTSVMRAAAEAGIDVPK MMAR_3639|M.marinum_M -------------------------------------------------- MUL_1474|M.ulcerans_Agy99 -------------------------------------------------- MAV_2075|M.avium_104 -------------------------------------------------- Mflv_3016|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3491|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 LCATDRLDAFGSCRLCLVEIDGRRGTPASCTTPVAEGMVVHTQTPKVAKL MMAR_3639|M.marinum_M -------------------------------------------------- MUL_1474|M.ulcerans_Agy99 -------------------------------------------------- MAV_2075|M.avium_104 -------------------------------------------------- Mflv_3016|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3491|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 RESVMELYISDHPLDCLTCPANGDCELQDMAGVVGLRQVRYGYEGANHFD MMAR_3639|M.marinum_M -------------------------------------------------- MUL_1474|M.ulcerans_Agy99 -------------------------------------------------- MAV_2075|M.avium_104 -------------------------------------------------- Mflv_3016|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3491|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2924c|M.bovis_AF2122/97 ---------------------------------------------MYVEA Rv2900c|M.tuberculosis_H37Rv ---------------------------------------------MYVEA MSMEG_0161|M.smegmatis_MC2_155 AEPDHSNPYFDFDPSKCIACSRCVRACGEIQGTFALTIEGRGFESKVSPG MMAR_3639|M.marinum_M --------------------------------MAPNKDAVKTVCAYCGVG MUL_1474|M.ulcerans_Agy99 --------------------------------MAPNKDAVKTVCAYCGVG MAV_2075|M.avium_104 ---------------------------------------MNTMCAYCGVG Mflv_3016|M.gilvum_PYR-GCK --------------------------------------MTRTACSYCGVG Mvan_3491|M.vanbaalenii_PYR-1 --------------------------------------MTRTACSYCGVG TH_4553|M.thermoresistible__bu -----------------------------VATGRGGADCVRTACSYCGVG MAB_2438|M.abscessus_ATCC_1997 ---------------------------------------MRTDAHAAGP- Mb2924c|M.bovis_AF2122/97 VRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQQMGAL Rv2900c|M.tuberculosis_H37Rv VRWQRSAASRDVLADYDEQAVTVAPRKREAAGVRAVMVSLQRGMQQMGAL MSMEG_0161|M.smegmatis_MC2_155 AGELFMDSECVSCGACVQACPTATLQERSVVELGIPTRSVTTTCAYCGVG * MMAR_3639|M.marinum_M CGIVLQTTTDPQTGKRRVAKSTGDKSHPANLGRLCTKGTTTADLLAA-PG MUL_1474|M.ulcerans_Agy99 CGIVLQTTTDPQTGKRRVAKSTGDKSHPANLGRLCTKGTTTADLLAA-PG MAV_2075|M.avium_104 CGMVLQITTDPQTGRRHVAKSVGNKEHPANFGRLCTKGATTADLLAA-PG Mflv_3016|M.gilvum_PYR-GCK CGISVETRTDPASGVPVIARVSGDKLHPTNFGRLCTKGATHAEMMAATDG Mvan_3491|M.vanbaalenii_PYR-1 CGISVETRTDPATGVPVIARVTGDKLHPSNFGRLCTKGATHAEMMAATDG TH_4553|M.thermoresistible__bu CGIEVRTTPGPAG--PVIAGVAGDPLHPTNRGRLCTKGATHAELMGSTKG MAB_2438|M.abscessus_ATCC_1997 ---------------VTVATVEGDVLHPSNQGRLCTKGATHAQLMAA-DG Mb2924c|M.bovis_AF2122/97 RTAAALARLNQRNGFDCPGCAWPEEPGGRKLAEFCENGAKAVAEEAT--K Rv2900c|M.tuberculosis_H37Rv RTAAALARLNQRNGFDCPGCAWPEEPGGRKLAEFCENGAKAVAEEAT--K MSMEG_0161|M.smegmatis_MC2_155 CSFKAELRGDE------LVRMVPQKAGGANEGHSCVKGRFAFGYATH-PD : : .. * :* MMAR_3639|M.marinum_M RMESAHLRAHRAGHLESIPIDDAITQCAMRLRAIIDEHG----------- MUL_1474|M.ulcerans_Agy99 RMESAHLRAHRAGHLESIPIDDAITQCAMRLRAIIDEHG----------- MAV_2075|M.avium_104 RMDSAHARAGRGEPLEPIGTDQAITRCAKQLRAIIDEHG----------- Mflv_3016|M.gilvum_PYR-GCK RLTTALVRPSRDADPVALDVDDAVAEAGSRLRAIVDEHG----------- Mvan_3491|M.vanbaalenii_PYR-1 RLTTALLRPSRDAEPVATDVDDALAEAGARLRAILDEHG----------- TH_4553|M.thermoresistible__bu RALTALIRPRRGEPPVPAPVDDAVAAAGQRLRAILDTHG----------- MAB_2438|M.abscessus_ATCC_1997 RMTTAHLRSIRGQQPIPAPLAAATAEAGRRLREILDNHG----------- Mb2924c|M.bovis_AF2122/97 RTVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRPISWDA Rv2900c|M.tuberculosis_H37Rv RTVTAEFFARHSVAELSAKPEYWLSQQGRLAHPMVLRPGDDHYRPISWDA MSMEG_0161|M.smegmatis_MC2_155 RVLRPMVRDKITDPWREVEWDEAINTVARRMQEIAQRHG----------- * . . : : * MMAR_3639|M.marinum_M --------------PDAVGVYVSGQMSIEAQYLANKLTKGFIGTNQIESN MUL_1474|M.ulcerans_Agy99 --------------PDAVGVYVSGQMSIEAQYLANKLTKGFIGTKQIESN MAV_2075|M.avium_104 --------------PDAFAMYVSGQMSLEAQYLANKLTKGFIGTNQIESN Mflv_3016|M.gilvum_PYR-GCK --------------PDAVALYVSGQMSIEAQYLATKLAKGFLRTVHIESN Mvan_3491|M.vanbaalenii_PYR-1 --------------PDAVALYVSGQMSIEAQYLATKLAKGFLRTVHIESN TH_4553|M.thermoresistible__bu --------------PDAIALYVSGQLSLEAQYLATKLAKGFIRTAHLEAN MAB_2438|M.abscessus_ATCC_1997 --------------PDAIALYVSGQMTLEAQYLANKLAKGYIRTTHIESN Mb2924c|M.bovis_AF2122/97 AYQLIAEQLNGLDSPDRAVFYTSGRTSNEAAFCYQLLVRSFG-TNNLPDC Rv2900c|M.tuberculosis_H37Rv AYQLIAEQLNGLDSPDRAVFYTSGRTSNEAAFCYQLLVRSFG-TNNLPDC MSMEG_0161|M.smegmatis_MC2_155 --------------AGAIGAITSSRCTNEEVYVVQKMVRAAFGNNNVDTC .. .*.: : * : :.:. . :: MMAR_3639|M.marinum_M SRLCMAGASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCHPILFL MUL_1474|M.ulcerans_Agy99 SRLCMAGASSGYKLSLGADGPPGSYQDFDHADVFLVIGANMADCHPILFL MAV_2075|M.avium_104 SRLCMASAGSGYKLSLGADGPPGSYQDFEHADVFFVIGANMADCHPILFL Mflv_3016|M.gilvum_PYR-GCK SRLCMASAGTGYKQSLGSDGPPGSYTDFDCTNLFFVIGSNMADCHPILYL Mvan_3491|M.vanbaalenii_PYR-1 SRLCMASAGTGFKQSLGADGPPGSYTDFDCTDLFFVIGSNMADCHPILYL TH_4553|M.thermoresistible__bu SRLCMASAASGYKQSLGADGPPGSYDDIDRADLFFVIGANMAPWP----- MAB_2438|M.abscessus_ATCC_1997 SRLCMASAGTGYAQSLGADGPPGSYSDIEHSDLFFVIGANMADCHPILFL Mb2924c|M.bovis_AF2122/97 SNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAGQNPGTNHPRMLS Rv2900c|M.tuberculosis_H37Rv SNMCHESSGAALTDSIGIGKGSVTIGDVEHADLIVIAGQNPGTNHPRMLS MSMEG_0161|M.smegmatis_MC2_155 ARVCHSPTGYGLKQTFGESAGTQDFRSVAEADVIVVIGANPTDGHPVFAS :.:* :. . ::* . . .. ::::.: * * MMAR_3639|M.marinum_M RMMERVKSGAKLIVVDPRRTA-----------------TADKADLFLQIA MUL_1474|M.ulcerans_Agy99 RMMERVKSGAKLIVVDPRRTA-----------------TADKADLFLQIA MAV_2075|M.avium_104 RMMDRVKAGAKLIVVDPRRTA-----------------TAEKADLFLQIA Mflv_3016|M.gilvum_PYR-GCK RMADRLKAGARLIVVDPRRTA-----------------TADKADLYLPIR Mvan_3491|M.vanbaalenii_PYR-1 RMADRLKAGAKLIVVDPRRTA-----------------TADKADLYLPIR TH_4553|M.thermoresistible__bu RSATSTRS------VAPR-------------------------------- MAB_2438|M.abscessus_ATCC_1997 RMADRLSSGARLIVVDPRRTA-----------------TADRADLFLQIT Mb2924c|M.bovis_AF2122/97 VLGKAKANGAKIIAVNPLPEAGLIRFKDPQKVNGVVGHGIPIADEFVQIR Rv2900c|M.tuberculosis_H37Rv VLGKAKANGAKIIAVNPLPEAGLIRFKDPQKVNGVVGHGIPIADEFVQIR MSMEG_0161|M.smegmatis_MC2_155 RMKQRIREGARLVVVDPRRIDLVR-------------SPHIEADHHLQLR * * MMAR_3639|M.marinum_M PGTDLALLNGLLHLIVENEQ------TDPQFISEFTEGWEVMPSFLEQ-- MUL_1474|M.ulcerans_Agy99 PGTDLALLNGLLHLIVENEQ------TDPQFISEFTEGWEVMPSFLEQ-- MAV_2075|M.avium_104 PGTDLALLNGLLHLIVENGH------TDGEFIAEFTEGWEVMPSFLEQ-- Mflv_3016|M.gilvum_PYR-GCK PGTDLALLNGILRVLVQDGA------IDEAFIAEHTEGWEAMPAFLAD-- Mvan_3491|M.vanbaalenii_PYR-1 PGTDLALLNGILHLLVENGA------VDQEFIAEHTQGWESMPEFLAG-- TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 PGTDLALLNGLLHLLVENGA------VDAEFIAQHTEGWDGMPEFLAG-- Mb2924c|M.bovis_AF2122/97 LGGDMALFAGLGRLLLEAEERVPGSVVDRSFVDNHCAGFDGYRRRTLQ-- Rv2900c|M.tuberculosis_H37Rv LGGDMALFAGLGRLLLEAEERVPGSVVDRSFVDNHCAGFDGYRRRTLQ-- MSMEG_0161|M.smegmatis_MC2_155 PGTNVAVVNAMAHVVVTEGL------TDASFVAERCEGFEEWAEFIAREE MMAR_3639|M.marinum_M FTPDRVSEITGIPSEDIRTAARWIGTAANWMSCWTMGLNQSTHGTWNTNA MUL_1474|M.ulcerans_Agy99 FTPDRVSEITGIPSEDIRTAARWIGTAANWMSCWTMGLNQSTHGTWNTNA MAV_2075|M.avium_104 YTPDRVSEITGIPEQDIRAAAQLIGEADNFMSCWTMGLNQSTHGTWNTNA Mflv_3016|M.gilvum_PYR-GCK YPPSRVAEITGLAEADIRSAAAMIAEAGDWISCWTMGLNQSTHGTWNTNA Mvan_3491|M.vanbaalenii_PYR-1 YPPDRVAAITGLSEADIRAAADMIAEAGDWLSCWTMGLNQSTHGTWNTNA TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 YAPAVVAAITGLAEEDIRTAARWIGEAREWMTLWTMGLNQSTHGTWNTNA Mb2924c|M.bovis_AF2122/97 VGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAVATIGE Rv2900c|M.tuberculosis_H37Rv VGLDTVMDATGIELAQLQRVAAMLMASQRTVICWAMGLTQHAHAVATIGE MSMEG_0161|M.smegmatis_MC2_155 NSPEAVEPITGVPAEELRAAARLYALAPNAAIYYGLGVTEHSQGSTMVMG MMAR_3639|M.marinum_M LCNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSVLSAP MUL_1474|M.ulcerans_Agy99 LCNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSVLSAP MAV_2075|M.avium_104 ICNLHLATGAICKPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSVASAA Mflv_3016|M.gilvum_PYR-GCK ICNLHLATGAICRPGAGPMSLTGQPNAMGGREMGYMGPGLPGQRAVLSAE Mvan_3491|M.vanbaalenii_PYR-1 ICNLHLATGAICRPGSGPMSLTGQPNAMGGREMGYMGPGLPGQRSVASAA TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 ICNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSVKSPA Mb2924c|M.bovis_AF2122/97 VTNVLLLRGMIGKPGAGVCPVRGHSNVQGDRTMG-----------IWEKM Rv2900c|M.tuberculosis_H37Rv VTNVLLLRGMIGKPGAGVCPVRGHSNVQGDRTMG-----------IWEKM MSMEG_0161|M.smegmatis_MC2_155 MANLAMACGNIGRDGVGVNPLRGQNNVQGSCDMGSFPHELPGYRHVSDDA MMAR_3639|M.marinum_M DREFVEEQWGLPGGALRTDVSGGVIDMFSRMADGEIKACWIICSNPVATV MUL_1474|M.ulcerans_Agy99 DREFVEEQWGLPGGALRTDVSGGVIDMFSRMADGEIKACWIICSNPVATV MAV_2075|M.avium_104 DREFVEDVWGVPRGRLRTEVGTGTIDMFSRMADGQIKACWIICTNPVASV Mflv_3016|M.gilvum_PYR-GCK DRSFVETQWDLEPGTVRTEVGPGTVEMFRRIAGGDIKAVWIICTNPVASV Mvan_3491|M.vanbaalenii_PYR-1 DRAFVEEQWDLEPGTIRADIGPGTVEMFRQMGSGDIKAAWIICTNPVASV TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 DRDFVEKRWQLPPGSIRAEFGTGTVDMFAQMAAGNIKACWIICTNPVASV Mb2924c|M.bovis_AF2122/97 PEQFLAALDREFGITSPRAHGFDTVAAIRAMRDGRVSVFMGMGGNFASAT Rv2900c|M.tuberculosis_H37Rv PEQFLAALDREFGITSPRAHGFDTVAAIRAMRDGRVSVFMGMGGNFASAT MSMEG_0161|M.smegmatis_MC2_155 VRQVFENLWGT---ELLAEPGLRIPNMFDAAIEGSFRGLFVHGEDIAQSD MMAR_3639|M.marinum_M ANRKTVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESDGVMVNC MUL_1474|M.ulcerans_Agy99 ANRKTVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESDGVMVNC MAV_2075|M.avium_104 ANRKTVLAGLERAELVIAQDAYLGTETSEYADVLLPAALWAETEGVMVNS Mflv_3016|M.gilvum_PYR-GCK ANRDTVITGLQSAELVITQDAYVDTATNRYADIMLPATLWAEADAVMVNS Mvan_3491|M.vanbaalenii_PYR-1 ANRDAVVAGLSTAELVITQDVYADTATNRYADIVLPATLWAETDAVMVNS TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 ANRKNVVDGLRRAELVIAQDAFLATATNEYADILLPAALWAESDGVSINS Mb2924c|M.bovis_AF2122/97 PDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALILPTLGRTDRDTRNG Rv2900c|M.tuberculosis_H37Rv PDTAVTEAALRRCALTVQVSTKLNRSHLVHGATALILPTLGRTDRDTRNG MSMEG_0161|M.smegmatis_MC2_155 PNVKHVLAALESMELVVVQDLFLN-ETSKYAHVFLPGASFLEKDGTFTNA MMAR_3639|M.marinum_M ERNMSLFPKAVDPVGDALPDWQIIARIACEMGFSESFSYSSAAEVFEEIK MUL_1474|M.ulcerans_Agy99 ERNMSLFPKAVDPVGDALPDWQIIARIACEMGFSESFSYSSAAEVFEEIK MAV_2075|M.avium_104 ERNITLSQPAVAAPGGAMPDWQIIARIACEMGFSEAFSYSCAEEVFEEIK Mflv_3016|M.gilvum_PYR-GCK GRTLTLLAQSVPAAGDARPDWELICGVARHLGFGDAFDHKSSEEIFDEIR Mvan_3491|M.vanbaalenii_PYR-1 DRNLTLLQQSVPPVGDARPDWELICGVARHLGFGDAFDYKSSEQIFDEIR TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 ERTATLTNRAVEAPGDARPDWQLICDIATAMGFGDAFGYSSSEEIFEEIR Mb2924c|M.bovis_AF2122/97 RKQLVSVEDSMSMVHLSR----------GSLHPPSDQVRSEVQIICQLAR Rv2900c|M.tuberculosis_H37Rv RKQLVSVEDSMSMVHLSR----------GSLHPPSDQVRSEVQIICQLAR MSMEG_0161|M.smegmatis_MC2_155 ERRINRVRAVMKPK-SGMHEWDIVCRIATAMGYPMHYDHPS--QIMDEIA MMAR_3639|M.marinum_M RFSNPATGYDLRGISHDRLRETPLQWPCPPDGASNRSPIRYLNDGVSQLQ MUL_1474|M.ulcerans_Agy99 RFSNPATGYDLRGISHDRLRETPLQWPCPPDGASNRSPIRYLNDGVSQLQ MAV_2075|M.avium_104 RFWNPTTGYDLRGVSYERLRRQPLQWPCPPQSTADRNPIRYLNDGVSQTQ Mflv_3016|M.gilvum_PYR-GCK RFHNPRTGYDLRGVTYERLRATPVQWPCPSEDAPDRNPIRYLNDGVSQDL Mvan_3491|M.vanbaalenii_PYR-1 RFHNPGTGYDLRGITYERLRDTPVQWPCASAEQSDRNPIRYLNDGVSQDQ TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 AFWNPRTGYDMRGMSYARLRQGPVQWPCPPESEVDRNPIRYLNDGISQHP Mb2924c|M.bovis_AF2122/97 ALFGPGHPVPWERFADDYDTIRDAIAAVVPGCDDYNHKVRVPDG------ Rv2900c|M.tuberculosis_H37Rv ALFGPGHPVPWERFADDYDTIRDAIAAVVPGCDDYNHKVRVPDG------ MSMEG_0161|M.smegmatis_MC2_155 TLTPTFTGVSFD----KLDQLGSIQWPCDEEAP----------------- MMAR_3639|M.marinum_M FVRADGTVPRLAFPTATGRAVFFARPHLVPDEMPDGDYPFLLNTGRLAHQ MUL_1474|M.ulcerans_Agy99 FVRADGTVPRLAFPTATGRAVFFARPHLVPDEMPDGDYPFLLNTGRLAHQ MAV_2075|M.avium_104 LVREDGTVPRLAFPTPSGRAVFFARPHLQPEEMPDDDYPFLLNTGRLPHQ Mflv_3016|M.gilvum_PYR-GCK HIDDDGHIPRLAFATPSRRAVFHPRPHLDAAELPDDDYPFILNTGRLQHQ Mvan_3491|M.vanbaalenii_PYR-1 YVGPDGHRPRLAFPTPSRRAVFHPRPHMDAAELPDDDYPLVLNTGRLQHQ TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 HVDENGVVPRLAFPTPSRRAVFHARAHRDPAELPGEGYPVVLNTGRLQHH Mb2924c|M.bovis_AF2122/97 FQLPHPPRDAREFRTSTGKANFAVNPLQWVPVPPGR---LVLQTLRSHDQ Rv2900c|M.tuberculosis_H37Rv FQLPHPPRDAREFRTSTGKANFAVNPLQWVPVPPGR---LVLQTLRSHDQ MSMEG_0161|M.smegmatis_MC2_155 ----EGTPIMHVDAFTRGLGRFVPTPFVPTDERSTRRFPLILTTGRILSQ MMAR_3639|M.marinum_M WHTLTKTGKIAKLNKLNPGPFVEVHPDDAADMQICEGDHIEIASRRGRAV MUL_1474|M.ulcerans_Agy99 WHTLTKTGKIAKLNKLNPGPFVEVHPDDAADMQICEGDHIEIASRRGRAV MAV_2075|M.avium_104 WHTMTKTGKVAKLNKLNPGPFVEIHPDDAARLGIGEHDRVEIASRRGRAV Mflv_3016|M.gilvum_PYR-GCK WHTMTKTGRVAKLTKLNPAPFVEIHPSDAAALGITDGQDLELRTRRGRAV Mvan_3491|M.vanbaalenii_PYR-1 WHTMTKTGKVAKLNKLNPGPFVEIHPDDAAALGISGGHDVELVTRRGRAV TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 WHTLTKTGRIKTLDRLHPSPFVEIHPHDATTLGISDGDIVEIASRRGTAE Mb2924c|M.bovis_AF2122/97 YNTTIYGLDDRYRGVKGGRRVVFINPADIETFGLTAGDRVDLVSEWTDGQ Rv2900c|M.tuberculosis_H37Rv YNTTIYGLDDRYRGVKGGRRVVFINPADIETFGLTAGDRVDLVSEWTDGQ MSMEG_0161|M.smegmatis_MC2_155 YNVGAQTRRTAN-IAWHAEDVLEIHPHDAEVRGIADGDLVTLASRVGETT MMAR_3639|M.marinum_M LPVVITDRVRPGNCFAPFHWNDAFGEYLSINAVTN-----DAVDPISRQP MUL_1474|M.ulcerans_Agy99 LPVVITDRVRPGNCFAPFHWNDAFGEYLSINAVTN-----DAVDPISRQP MAV_2075|M.avium_104 LPAVVSDRVRPGNCFAPFHWNDAFGEYLSINAVTN-----DAVDPISNQP Mflv_3016|M.gilvum_PYR-GCK LPAVLTERVRPGNTWAPFHWNDEHGENLTINALTN-----DAVDPDSLQP Mvan_3491|M.vanbaalenii_PYR-1 LPAVLTDRVQPGNTWVPFHWNDEHGDHLTVNALTN-----DAVDPDSLQP TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 LPALVSDRVKRGSCFAPFHWNDAHGPGLTINAVTN-----DAVDPDSLQP Mb2924c|M.bovis_AF2122/97 G----GLQERRAKDFLVVAYSTPVGNAAAYYPETNPLVPLDHTAAQSNTP Rv2900c|M.tuberculosis_H37Rv G----GLQERRAKDFLVVAYSTPVGNAAAYYPETNPLVPLDHTAAQSNTP MSMEG_0161|M.smegmatis_MC2_155 LHAQTSDRMPTGVVYTTFHYPVTGANVVTT----------DSSDWATNCP MMAR_3639|M.marinum_M EYKACAVTLTKVARPQLQPEPGEPADTCADATAPKLLADTAQFSVTQVDA MUL_1474|M.ulcerans_Agy99 EYKACAVTLTKVARPQLQPEPGEPADACADATAPKLLADTAQFSVTQVDA MAV_2075|M.avium_104 EFKACAVTLTKVAVSHPDSAIG-TGPSAGHDTPESAPTEVREISVSQVDA Mflv_3016|M.gilvum_PYR-GCK EFKVCAVRLTPVPAADG--------------------------------- Mvan_3491|M.vanbaalenii_PYR-1 EFKVCAVRLAPVPAAG---------------------------------- TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 EFKVSAVALRPT-------------------------------------- Mb2924c|M.bovis_AF2122/97 VSKAIIVRLEPTA------------------------------------- Rv2900c|M.tuberculosis_H37Rv VSKAIIVRLEPTA------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 EYKVTAVQVALAP------------------------------------- MMAR_3639|M.marinum_M LAELLGVANEPTPQFGPFARSYLAGLIAGLRSETGRRMAGVPTLPVSSPF MUL_1474|M.ulcerans_Agy99 LAELLGVGNEPTPQFGPSARSYLAGLIAGLRSETGRRMAGVSTLPISSPF MAV_2075|M.avium_104 LGELLGVATSFKPEFNELGRSYLAGMLTGLRSDVGRRAGGVPTLPPSAPF Mflv_3016|M.gilvum_PYR-GCK -----------APDLTDDEKLYIAGFLAGVDEGR----PGVPVLPAGAPV Mvan_3491|M.vanbaalenii_PYR-1 -----------APEFTETEKLYLAGFFAGIEEGL----PGVPVLPASAPV TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 -------------------------------------------------- Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M DTGTRLWLDGLLAGMFARAETPPALPFPQTPGAAAQSDNAAEA----AVE MUL_1474|M.ulcerans_Agy99 DTGTRLWLDGLLAGMFARAETPPALPFPQTPGAAAQSDNAAEA----AVE MAV_2075|M.avium_104 DSRTRLWVDGLLAGLFSRADASQQAALPEPPQPAAQQPPAAPAGATPAPE Mflv_3016|M.gilvum_PYR-GCK GARARLWVDGLLAGRYSRLETAAPSAS----------------------P Mvan_3491|M.vanbaalenii_PYR-1 GPRARLWVDGLLAGRYSRSDTVAETPA----------------------T TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 -------------GRTKADSMPEKQKE----------------------A Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M QPPIVVLWASQTGTAEELAASVAAQLSAAELPVVLHGMDEFAVADLVSTQ MUL_1474|M.ulcerans_Agy99 QPPIVVLWASQTGTAEELAASVAAQLSAAELPVVLHGMDEFAVADLVSTQ MAV_2075|M.avium_104 RAPVVVLWASQTGNAEELAADVAAQLAAAELPVALHSMDDFPAAELAATR Mflv_3016|M.gilvum_PYR-GCK RGGPLVLWASQTGTAEEFAGSLGERLAGA----RLRAMDDTDLSELSDAG Mvan_3491|M.vanbaalenii_PYR-1 EG-PLVLWASQTGNAEEFAGRLGERLNGA----RLRAMDDVELDDLSEAG TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 LGDVAILWTSQTGNAETAAVSVHRLLHTAGISATITAMDECDPADLVGVN Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M RLLLVTSTTGDGEPPDNGAAFWRELCAATAPSLAGTRYSVLALGDSNYAD MUL_1474|M.ulcerans_Agy99 RLLLVTSTTGDGEPPDNGAAFWRELCAPTAPSLAGTRYSVLALGDSNYAD MAV_2075|M.avium_104 ELLLITSTTGDGDAPDNGSGLWRALTGDAAPRLGNTRYAVLALGDSNYDD Mflv_3016|M.gilvum_PYR-GCK EVVIVTSTFGDGGPPDNGTAFWERLESADAPALDGVRYTVLGIGDRSYDN Mvan_3491|M.vanbaalenii_PYR-1 EVVIVTSTFGDGGPPDNGAGFWERLESPHAPSLDGVRYTVLGIGDRSYDN TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 TAVVIASSFGEGGPPDNGARFWAALSG-DTKPLNHMRYAVLGFGDRAYAD Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M FCGHGRALDHRLAELGASRVTDRVDCEPDYEESAARWLQEVLDGLRRTAP MUL_1474|M.ulcerans_Agy99 FCGHGRALDHRLAELGASRITDRVDCEPDYEESAARWLQEVLDGLRRTAP MAV_2075|M.avium_104 FCGHGRKLDARLAELGATRIAERVDCEPDYEQAAAKWVADVIEALTRTPT Mflv_3016|M.gilvum_PYR-GCK FCGHAKSLDTRLADLGATRMLDRADCEAYDEQPMAAWADSVVGLMST--- Mvan_3491|M.vanbaalenii_PYR-1 FCGHARSLDARLADLGATRMLDRVECEAYDAQPLARWADSVVELVAA--- TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 FCGHAKALDARLHELGASPLLGRVDGEATDRTLVASWTADLLDAIGDGAT Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 --PSARQAEARVDELPETELVR---------------------------- MMAR_3639|M.marinum_M PV---------ITAAPVRAASIANR--PQGYTKKRPLLTSVMRNTTLSRP MUL_1474|M.ulcerans_Agy99 PV---------ITAEPVRAASIASR--PQGYTKKRPLLTSVMRNTTLSRP MAV_2075|M.avium_104 AVGGDGGATVSARTSPVAAPSRPNTPAPHTYSKKHPLITDMVRNTTLNGP Mflv_3016|M.gilvum_PYR-GCK -------------PVTPAPTQPAVPAAPAPFTRGNPAQAPLCRNVRLTPD Mvan_3491|M.vanbaalenii_PYR-1 -------------PGTPP---AAPAQEPTLFTRAEPVAAPLCRNTRLTPQ TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 AI---------VETVRKLRSEGLRVAAPERFTRDAPILAALSHNELLSAP Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M RSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQLVDEWLGVTQLDGHT MUL_1474|M.ulcerans_Agy99 RSAKDVRQLVFRVPEQTVSYEAGDALGVWPRNAHQLVDEWLGVTRLDGHT MAV_2075|M.avium_104 KSTKDVRHLVFNLPEDAVSYEAGDALGVWPRNSDELVDEWLAVTGLDGQT Mflv_3016|M.gilvum_PYR-GCK GAGKDVRQFGFDISGQDLAYSVGDSLGVWVVNSDAVVESWLSATGFHGAE Mvan_3491|M.vanbaalenii_PYR-1 GAAKEVRQIGFDISAHDVTYSVGDSLGVCVVNSDFVVENWLAATDLRGDE TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 NSGKEVRRIEFDLTGHDVSYSAGDALGIYPTNREEDVQRWLTTTGFDAQL Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M EVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQRTLDSNTANQLAELM MUL_1474|M.ulcerans_Agy99 EVEVAGHGTMSLRAALTDRFEIAHLSPDLLRFVAQRTLDSNTANQLAELM MAV_2075|M.avium_104 PVEVGEHGLMSLRSALTERIEIAHISRDLVRFVQERTGDA----KLAELL Mflv_3016|M.gilvum_PYR-GCK AVIVDGR-QISLREALTRHYDVCKVTSNLVTFVAEHCPDA----ATAKRL Mvan_3491|M.vanbaalenii_PYR-1 AVVVDGV-QQALRDALTAHYDVCKVTSNLVKFVAEHCRDA----ATAKRL TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 PVTIDGG-ELPLATALANHYDICRVTEDLLRFIAERRRDK----HSAKLL Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M RPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSVLKPIQPRLYSISSS MUL_1474|M.ulcerans_Agy99 RPENKAALADWTWGRQSVDLLAQSPVRASVDEWMSVLKPIQPRLYSISSS MAV_2075|M.avium_104 KPENKRALADWTWGRQSIDLLAQLPVSASAHEWLRVLKRLQPRLYSISSS Mflv_3016|M.gilvum_PYR-GCK RN-DRGALDTWLVDRNGLDLVREFGIRADPALWQEVLVRLTPRQYSISSS Mvan_3491|M.vanbaalenii_PYR-1 RN-DRGELDRWLVNRNGLDLVREFSVRADPQLWQEVLVRLTPRQYSISSS TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 QGRDTQAREVWLRGRNALDVIREFPIRAAIEEWQQVLIRLTPRQYSISSS Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M PKEHPGEVHLTVSPVRYN-FQGVPRRGVCSTYLADRSPSDQIAIYVRKSS MUL_1474|M.ulcerans_Agy99 PKEHPGEVHLTVSPVRYN-FQGVPRRGVCSTYLADRSPSDQIAIYVRKSS MAV_2075|M.avium_104 PKACPGEVHLTVSPVRYN-FQGVPRRGVCSTYLAARSPGDRVAVYLQPSS Mflv_3016|M.gilvum_PYR-GCK PLVSPHEVQLTVSVVRYRGADGTPRGGVASTYLADLPDCTPVPVFLQRSP Mvan_3491|M.vanbaalenii_PYR-1 PLVSPNEVQLTVSVVRYRGADGGPRGGVASTYLADLPDGTAVPVFLQRSP TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 PLVSPQAISLTVSIVRYQGPDGSPRGGVGSTFLADRAQHLPVPIFLQRSP Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M NFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGHTGPNWLFFGEQHAA MUL_1474|M.ulcerans_Agy99 NFRPPSDPRTPMIMIGPGTGIAPFRGFLQERRALGHTGPNWLFFGEQHAA MAV_2075|M.avium_104 NFRPPSDPDTPMIMIGPGTGIAPFRGFLQERRALGHRGPNWLFFGEQHAA Mflv_3016|M.gilvum_PYR-GCK HFRPPEDPHTPMIMVGPGTGIAPFRGFLQERRALGHRGANWLFFGDQHRE Mvan_3491|M.vanbaalenii_PYR-1 HFRPPQDSHTPMIMVGPGTGIAPFRGFLQERRALGHRGPNWLFFGDQHRA TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 HFRPPRTSDTPMIMIGPGTGIAPFRGFLQERRALGHTGANWLFFGDQHRT Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M TDFYYRDEIQAMHRDGLLTNLDLAFSRDQRDKVYVQHLMQQRGAQLWQWL MUL_1474|M.ulcerans_Agy99 TDFYYRDEIQAMHRDGLLTNLDLAFSRDQRDKVYVQHLMQQRGAQLWQWL MAV_2075|M.avium_104 TDFYYRDELEQMREDGFLTELDLAFSRDQQHKVYVQHLMRNRGKQLWSWL Mflv_3016|M.gilvum_PYR-GCK QNFYYRDDLLDMVDDGFLNRLDLAFSRDQRQRIYVQHKMLDYGADVWRWL Mvan_3491|M.vanbaalenii_PYR-1 QNFYYRDDLQDMVDDGFLNRLDLAFSRDQARRVYVQHKMLDYGADVWRWL TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 EHFYYRDELDGFLRDGSLRRLDLAFSRDQAKRIYVQHRMMEQGAQLWRWL Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M QDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGLDPESATAFVHALSADKR MUL_1474|M.ulcerans_Agy99 QDGAQVYVCGTADPMAKDVDRMLCQIVAEHGGLDPESATAFVHALSADKR MAV_2075|M.avium_104 QDGAQLYVCGTADPMAKDVDRALCDIAAEFGNLDPDAAKAYVQSLSADKR Mflv_3016|M.gilvum_PYR-GCK DDGAHFYVCGDATRMAKDVDDALTEILRTHARMSSDAAREYKREMVAEKR Mvan_3491|M.vanbaalenii_PYR-1 DDGAHFYVCGDATRMAGDVDDALTEIIRTHGGMSADAARDYKREMVAEKR TH_4553|M.thermoresistible__bu -------------------------------------------------- MAB_2438|M.abscessus_ATCC_1997 NEGAHLYVCGDASRMAKDVDGALLTIAQKHGKLSGEQALEFRKELVAEKR Mb2924c|M.bovis_AF2122/97 -------------------------------------------------- Rv2900c|M.tuberculosis_H37Rv -------------------------------------------------- MSMEG_0161|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_3639|M.marinum_M YHRDVY MUL_1474|M.ulcerans_Agy99 YHRDVY MAV_2075|M.avium_104 YHRDVY Mflv_3016|M.gilvum_PYR-GCK YVRDVY Mvan_3491|M.vanbaalenii_PYR-1 YVRDVY TH_4553|M.thermoresistible__bu ------ MAB_2438|M.abscessus_ATCC_1997 YVRDVY Mb2924c|M.bovis_AF2122/97 ------ Rv2900c|M.tuberculosis_H37Rv ------ MSMEG_0161|M.smegmatis_MC2_155 ------