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VTRTACSYCGVGCGISVETRTDPASGVPVIARVSGDKLHPTNFGRLCTKGATHAEMMAATDGRLTTALVR PSRDADPVALDVDDAVAEAGSRLRAIVDEHGPDAVALYVSGQMSIEAQYLATKLAKGFLRTVHIESNSRL CMASAGTGYKQSLGSDGPPGSYTDFDCTNLFFVIGSNMADCHPILYLRMADRLKAGARLIVVDPRRTATA DKADLYLPIRPGTDLALLNGILRVLVQDGAIDEAFIAEHTEGWEAMPAFLADYPPSRVAEITGLAEADIR SAAAMIAEAGDWISCWTMGLNQSTHGTWNTNAICNLHLATGAICRPGAGPMSLTGQPNAMGGREMGYMGP GLPGQRAVLSAEDRSFVETQWDLEPGTVRTEVGPGTVEMFRRIAGGDIKAVWIICTNPVASVANRDTVIT GLQSAELVITQDAYVDTATNRYADIMLPATLWAEADAVMVNSGRTLTLLAQSVPAAGDARPDWELICGVA RHLGFGDAFDHKSSEEIFDEIRRFHNPRTGYDLRGVTYERLRATPVQWPCPSEDAPDRNPIRYLNDGVSQ DLHIDDDGHIPRLAFATPSRRAVFHPRPHLDAAELPDDDYPFILNTGRLQHQWHTMTKTGRVAKLTKLNP APFVEIHPSDAAALGITDGQDLELRTRRGRAVLPAVLTERVRPGNTWAPFHWNDEHGENLTINALTNDAV DPDSLQPEFKVCAVRLTPVPAADGAPDLTDDEKLYIAGFLAGVDEGRPGVPVLPAGAPVGARARLWVDGL LAGRYSRLETAAPSASPRGGPLVLWASQTGTAEEFAGSLGERLAGARLRAMDDTDLSELSDAGEVVIVTS TFGDGGPPDNGTAFWERLESADAPALDGVRYTVLGIGDRSYDNFCGHAKSLDTRLADLGATRMLDRADCE AYDEQPMAAWADSVVGLMSTPVTPAPTQPAVPAAPAPFTRGNPAQAPLCRNVRLTPDGAGKDVRQFGFDI SGQDLAYSVGDSLGVWVVNSDAVVESWLSATGFHGAEAVIVDGRQISLREALTRHYDVCKVTSNLVTFVA EHCPDAATAKRLRNDRGALDTWLVDRNGLDLVREFGIRADPALWQEVLVRLTPRQYSISSSPLVSPHEVQ LTVSVVRYRGADGTPRGGVASTYLADLPDCTPVPVFLQRSPHFRPPEDPHTPMIMVGPGTGIAPFRGFLQ ERRALGHRGANWLFFGDQHREQNFYYRDDLLDMVDDGFLNRLDLAFSRDQRQRIYVQHKMLDYGADVWRW LDDGAHFYVCGDATRMAKDVDDALTEILRTHARMSSDAAREYKREMVAEKRYVRDVY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3016 | - | - | 100% (1317) | molybdopterin oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0347 | - | 8e-94 | 40.15% (538) | FAD-binding domain-containing protein |
| M. gilvum PYR-GCK | Mflv_5161 | - | 5e-37 | 25.32% (695) | molybdopterin oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0203 | - | 8e-25 | 23.76% (728) | oxidoreductase |
| M. tuberculosis H37Rv | Rv0197 | - | 1e-24 | 23.76% (728) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2438 | - | 0.0 | 59.97% (1314) | oxidoreductase |
| M. marinum M | MMAR_3639 | fdhF | 0.0 | 53.94% (1396) | formate dehydrogenase H FdhF |
| M. avium 104 | MAV_2075 | - | 0.0 | 55.62% (1406) | FdhF protein |
| M. smegmatis MC2 155 | MSMEG_2837 | - | 5e-92 | 32.20% (736) | nitrate reductase NarB |
| M. thermoresistible (build 8) | TH_4553 | - | 5e-72 | 74.01% (177) | PUTATIVE sulfite reductase (NADPH) alpha subunit |
| M. ulcerans Agy99 | MUL_1474 | fdhF | 0.0 | 53.65% (1396) | formate dehydrogenase H FdhF |
| M. vanbaalenii PYR-1 | Mvan_3491 | - | 0.0 | 84.52% (1318) | molybdopterin oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3016|M.gilvum_PYR-GCK ------------------------------------MTRTACSYCGVGCG
Mvan_3491|M.vanbaalenii_PYR-1 ------------------------------------MTRTACSYCGVGCG
TH_4553|M.thermoresistible__bu ---------------------------VATGRGGADCVRTACSYCGVGCG
MMAR_3639|M.marinum_M ------------------------------MAPNKDAVKTVCAYCGVGCG
MUL_1474|M.ulcerans_Agy99 ------------------------------MAPNKDAVKTVCAYCGVGCG
MAV_2075|M.avium_104 -------------------------------------MNTMCAYCGVGCG
MAB_2438|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 MARTDRISDPWGSRTPYAAGEPWPQRVDRYLTPGLTDDDVDRWVQSAAVL
Mb0203|M.bovis_AF2122/97 -------------------------------MTSSDWLPTACILCECNCG
Rv0197|M.tuberculosis_H37Rv -------------------------------MTSSDWLPTACILCECNCG
Mflv_3016|M.gilvum_PYR-GCK ISVETRTDPASGVPVIARVSGDKLHPTNFGRLCTKGATHAEMMAATDGRL
Mvan_3491|M.vanbaalenii_PYR-1 ISVETRTDPATGVPVIARVTGDKLHPSNFGRLCTKGATHAEMMAATDGRL
TH_4553|M.thermoresistible__bu IEVRTTPGPAG--PVIAGVAGDPLHPTNRGRLCTKGATHAELMGSTKGRA
MMAR_3639|M.marinum_M IVLQTTTDPQTGKRRVAKSTGDKSHPANLGRLCTKGTTTADLLAAP-GRM
MUL_1474|M.ulcerans_Agy99 IVLQTTTDPQTGKRRVAKSTGDKSHPANLGRLCTKGTTTADLLAAP-GRM
MAV_2075|M.avium_104 MVLQITTDPQTGRRHVAKSVGNKEHPANFGRLCTKGATTADLLAAP-GRM
MAB_2438|M.abscessus_ATCC_1997 ---MRTDAHAAGPVTVATVEGDVLHPSNQGRLCTKGATHAQLMAAD-GRM
MSMEG_2837|M.smegmatis_MC2_155 HSNGDGLDIAVKDGRIVGVRGRADDRVNHGRLDPKDLFGWQANHAR-DRL
Mb0203|M.bovis_AF2122/97 IVVQVDD------RRLARIRGDKAHPGSAGYTCNKALRLDHYQNNR--AR
Rv0197|M.tuberculosis_H37Rv IVVQVDD------RRLARIRGDKAHPGSAGYTCNKALRLDHYQNNR--AR
:. * . . * * .
Mflv_3016|M.gilvum_PYR-GCK TTALVRPSRDADPVALDVDDAVAEAGSRLRAIVDEHGPDAVALYVSGQMS
Mvan_3491|M.vanbaalenii_PYR-1 TTALLRPSRDAEPVATDVDDALAEAGARLRAILDEHGPDAVALYVSGQMS
TH_4553|M.thermoresistible__bu LTALIRPRRGEPPVPAPVDDAVAAAGQRLRAILDTHGPDAIALYVSGQLS
MMAR_3639|M.marinum_M ESAHLRAHRAGHLESIPIDDAITQCAMRLRAIIDEHGPDAVGVYVSGQMS
MUL_1474|M.ulcerans_Agy99 ESAHLRAHRAGHLESIPIDDAITQCAMRLRAIIDEHGPDAVGVYVSGQMS
MAV_2075|M.avium_104 DSAHARAGRGEPLEPIGTDQAITRCAKQLRAIIDEHGPDAFAMYVSGQMS
MAB_2438|M.abscessus_ATCC_1997 TTAHLRSIRGQQPIPAPLAAATAEAGRRLREILDNHGPDAIALYVSGQMT
MSMEG_2837|M.smegmatis_MC2_155 RTPLIR--QDGVLVESDWDTAMDRIVARSRQLLDERGPNSIGFYTSGQLF
Mb0203|M.bovis_AF2122/97 LSSPMRRRADGTYEEIDWDTAIVEIAEGFKQIRDTHGGDKIFYYGGGGQ-
Rv0197|M.tuberculosis_H37Rv LSSPMRRRADGTYEEIDWDTAIVEIAEGFKQIRDTHGGDKIFYYGGGGQ-
:. * * : : * :* : . * .*
Mflv_3016|M.gilvum_PYR-GCK IEAQYLATKLAKGFLRTVHIESNSRLCMASAGTGYKQSLGSDGPPGSYTD
Mvan_3491|M.vanbaalenii_PYR-1 IEAQYLATKLAKGFLRTVHIESNSRLCMASAGTGFKQSLGADGPPGSYTD
TH_4553|M.thermoresistible__bu LEAQYLATKLAKGFIRTAHLEANSRLCMASAASGYKQSLGADGPPGSYDD
MMAR_3639|M.marinum_M IEAQYLANKLTKGFIGTNQIESNSRLCMAGASSGYKLSLGADGPPGSYQD
MUL_1474|M.ulcerans_Agy99 IEAQYLANKLTKGFIGTKQIESNSRLCMAGASSGYKLSLGADGPPGSYQD
MAV_2075|M.avium_104 LEAQYLANKLTKGFIGTNQIESNSRLCMASAGSGYKLSLGADGPPGSYQD
MAB_2438|M.abscessus_ATCC_1997 LEAQYLANKLAKGYIRTTHIESNSRLCMASAGTGYAQSLGADGPPGSYSD
MSMEG_2837|M.smegmatis_MC2_155 LEEYYTQCVIAHGAIGTNHVDGNTRLCTATAAEALKESFGCDGQPGSYTD
Mb0203|M.bovis_AF2122/97 --GNHLGGAYSGAFLKALGSRYRSNALAQEKTGEAWVDFQLYGG-HTRGE
Rv0197|M.tuberculosis_H37Rv --GNHLGGAYSGAFLKALGSRYRSNALAQEKTGEAWVDFQLYGG-HTRGE
: : . : : .:. .: * : :
Mflv_3016|M.gilvum_PYR-GCK FDCTNLFFVIGSN--MADCHPILYLRMADRLKAG--ARLIVVDPRRTATA
Mvan_3491|M.vanbaalenii_PYR-1 FDCTDLFFVIGSN--MADCHPILYLRMADRLKAG--AKLIVVDPRRTATA
TH_4553|M.thermoresistible__bu IDRADLFFVIGAN--MAPWP-----RSATSTRS--------VAPR-----
MMAR_3639|M.marinum_M FDHADVFLVIGAN--MADCHPILFLRMMERVKSG--AKLIVVDPRRTATA
MUL_1474|M.ulcerans_Agy99 FDHADVFLVIGAN--MADCHPILFLRMMERVKSG--AKLIVVDPRRTATA
MAV_2075|M.avium_104 FEHADVFFVIGAN--MADCHPILFLRMMDRVKAG--AKLIVVDPRRTATA
MAB_2438|M.abscessus_ATCC_1997 IEHSDLFFVIGAN--MADCHPILFLRMADRLSSG--ARLIVVDPRRTATA
MSMEG_2837|M.smegmatis_MC2_155 VDHADVIALYGHN--VAETQTVLWMRMLDRLAGPNPPAIVCIDPRPTPVA
Mb0203|M.bovis_AF2122/97 FENAEVSVFVGKNPWMSQSFPRARVVLNEIAKDPG-RSMIVIDPVVTDTA
Rv0197|M.tuberculosis_H37Rv FENAEVSVFVGKNPWMSQSFPRARVVLNEIAKDPG-RSMIVIDPVVTDTA
.: ::: . * * :: : *
Mflv_3016|M.gilvum_PYR-GCK DKADLYLPIRPGTDLALLNGILRVLVQDGAIDEAFIAEHTEGWEAMPAFL
Mvan_3491|M.vanbaalenii_PYR-1 DKADLYLPIRPGTDLALLNGILHLLVENGAVDQEFIAEHTQGWESMPEFL
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M DKADLFLQIAPGTDLALLNGLLHLIVENEQTDPQFISEFTEGWEVMPSFL
MUL_1474|M.ulcerans_Agy99 DKADLFLQIAPGTDLALLNGLLHLIVENEQTDPQFISEFTEGWEVMPSFL
MAV_2075|M.avium_104 EKADLFLQIAPGTDLALLNGLLHLIVENGHTDGEFIAEFTEGWEVMPSFL
MAB_2438|M.abscessus_ATCC_1997 DRADLFLQITPGTDLALLNGLLHLLVENGAVDAEFIAQHTEGWDGMPEFL
MSMEG_2837|M.smegmatis_MC2_155 RHATVHLAPLPGTNVALMNGLLHEILDHDWMDHDYIEAHTVGFHELRKRV
Mb0203|M.bovis_AF2122/97 KMADFHLRVQPGCDAWCLAALAAVLVQENLCNEAFLAAHVHGVDTVRAAL
Rv0197|M.tuberculosis_H37Rv KMADFHLRVQPGCDAWCLAALAAVLVQENLCNEAFLAAHVHGVDTVRAAL
Mflv_3016|M.gilvum_PYR-GCK ADYPPSRVAEITGLAEADIRSAAAMIAEAGDWISCWTMGLNQSTHGTWNT
Mvan_3491|M.vanbaalenii_PYR-1 AGYPPDRVAAITGLSEADIRAAADMIAEAGDWLSCWTMGLNQSTHGTWNT
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M EQFTPDRVSEITGIPSEDIRTAARWIGTAANWMSCWTMGLNQSTHGTWNT
MUL_1474|M.ulcerans_Agy99 EQFTPDRVSEITGIPSEDIRTAARWIGTAANWMSCWTMGLNQSTHGTWNT
MAV_2075|M.avium_104 EQYTPDRVSEITGIPEQDIRAAAQLIGEADNFMSCWTMGLNQSTHGTWNT
MAB_2438|M.abscessus_ATCC_1997 AGYAPAVVAAITGLAEEDIRTAARWIGEAREWMTLWTMGLNQSTHGTWNT
MSMEG_2837|M.smegmatis_MC2_155 AEFPPERVADICGVDPDDVRRAGELIGTAERLLSTVLQGFYQSHQATAAA
Mb0203|M.bovis_AF2122/97 QEVPVADYAQRCGVDEELLRAAARRIGTAASVSVFEDLGIQQAPNSTVCS
Rv0197|M.tuberculosis_H37Rv QEVPVADYAQRCGVDEELLRAAARRIGTAASVSVFEDLGIQQAPNSTVCS
Mflv_3016|M.gilvum_PYR-GCK NAICNLHLATGAICRPGAGPMSLTGQPNAMGGREMGYMGPGLPGQRAVLS
Mvan_3491|M.vanbaalenii_PYR-1 NAICNLHLATGAICRPGSGPMSLTGQPNAMGGREMGYMGPGLPGQRSVAS
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M NALCNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSVLS
MUL_1474|M.ulcerans_Agy99 NALCNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSVLS
MAV_2075|M.avium_104 NAICNLHLATGAICKPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSVAS
MAB_2438|M.abscessus_ATCC_1997 NAICNLHLATGAICRPGSGPFSLTGQPNAMGGREMGYMGPGLPGQRSVKS
MSMEG_2837|M.smegmatis_MC2_155 VQVNNIHLVRGMLGRPGCGLLQMNGQPTAENTRECGADG-DLAGFRNWAN
Mb0203|M.bovis_AF2122/97 YLNKLLWILTGNFAKKGGQHLHSSFAPLFSQVSGRTPVTGAPIIAGLIPG
Rv0197|M.tuberculosis_H37Rv YLNKLLWILTGNFAKKGGQHLHSSFAPLFSQVSGRTPVTGAPIIAGLIPG
Mflv_3016|M.gilvum_PYR-GCK AEDRSFVETQWDLEPGTVRTEVG-PGTVEMFRRIAGGDIKAVWIICTNPV
Mvan_3491|M.vanbaalenii_PYR-1 AADRAFVEEQWDLEPGTIRADIG-PGTVEMFRQMGSGDIKAAWIICTNPV
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M APDREFVEEQWGLPGGALRTDVS-GGVIDMFSRMADGEIKACWIICSNPV
MUL_1474|M.ulcerans_Agy99 APDREFVEEQWGLPGGALRTDVS-GGVIDMFSRMADGEIKACWIICSNPV
MAV_2075|M.avium_104 AADREFVEDVWGVPRGRLRTEVG-TGTIDMFSRMADGQIKACWIICTNPV
MAB_2438|M.abscessus_ATCC_1997 PADRDFVEKRWQLPPGSIRAEFG-TGTVDMFAQMAAGNIKACWIICTNPV
MSMEG_2837|M.smegmatis_MC2_155 DSHIEELATLWNLDVTAIPHYAPPTHAMQMFRYAEEGSLRMLWVSATNPA
Mb0203|M.bovis_AF2122/97 NVVPEEILTEHPDRFRAMIVESGNPAHSLADSAACRAAFQALELMVVVDV
Rv0197|M.tuberculosis_H37Rv NVVPEEILTEHPDRFRAMIVERGNPAHSLADSAACRAAFQALELMVVVDV
Mflv_3016|M.gilvum_PYR-GCK ASVANRDTVITGLQSAELVITQDAYVDTATNRYADIMLPATLWAEADAVM
Mvan_3491|M.vanbaalenii_PYR-1 ASVANRDAVVAGLSTAELVITQDVYADTATNRYADIVLPATLWAETDAVM
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M ATVANRKTVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESDGVM
MUL_1474|M.ulcerans_Agy99 ATVANRKTVLAGLEKAELVISQDAFFETETNEYANVLLPAALWTESDGVM
MAV_2075|M.avium_104 ASVANRKTVLAGLERAELVIAQDAYLGTETSEYADVLLPAALWAETEGVM
MAB_2438|M.abscessus_ATCC_1997 ASVANRKNVVDGLRRAELVIAQDAFLATATNEYADILLPAALWAESDGVS
MSMEG_2837|M.smegmatis_MC2_155 VSLPELGRIRRILSQDRLFLVVQDLFLTETAQLADVVLPAAAWAEKTGTF
Mb0203|M.bovis_AF2122/97 AMTETARLAHYVLPAASQFEKPEATFFNFEFPRNGFQLRRPLFPPLPGTL
Rv0197|M.tuberculosis_H37Rv AMTETARLAHYVLPAASQFEKPEATFFNFEFPRNGFQLRRPLFPPLPGTL
Mflv_3016|M.gilvum_PYR-GCK VNSGRTLTLLAQS-VPAAGDARPDWELICGVARHLGFGDAFD-----HKS
Mvan_3491|M.vanbaalenii_PYR-1 VNSDRNLTLLQQS-VPPVGDARPDWELICGVARHLGFGDAFD-----YKS
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M VNCERNMSLFPKA-VDPVGDALPDWQIIARIACEMGFSESFS-----YSS
MUL_1474|M.ulcerans_Agy99 VNCERNMSLFPKA-VDPVGDALPDWQIIARIACEMGFSESFS-----YSS
MAV_2075|M.avium_104 VNSERNITLSQPA-VAAPGGAMPDWQIIARIACEMGFSEAFS-----YSC
MAB_2438|M.abscessus_ATCC_1997 INSERTATLTNRA-VEAPGDARPDWQLICDIATAMGFGDAFG-----YSS
MSMEG_2837|M.smegmatis_MC2_155 TNADRTVHISDKA-VDPPGQARSDFDIFLDYARRMDFRDRDGRPLPAWNT
Mb0203|M.bovis_AF2122/97 PEPEIWARLVRALGVVDEADLRPLREAAAQGRQAYTEAFLAAAATNPTVA
Rv0197|M.tuberculosis_H37Rv PEPEIWARLVRALGVVDEADLRPLREAAAQGRQAYTEAFLAAAATNPTVA
Mflv_3016|M.gilvum_PYR-GCK SEEIFDEIRRFHNPRTGYDLRGVTYERLR-ATPVQWPCPSEDAPDRNPIR
Mvan_3491|M.vanbaalenii_PYR-1 SEQIFDEIRRFHNPGTGYDLRGITYERLR-DTPVQWPCASAEQSDRNPIR
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M AAEVFEEIKRFSNPATGYDLRGISHDRLR-ETPLQWPCPPDGASNRSPIR
MUL_1474|M.ulcerans_Agy99 AAEVFEEIKRFSNPATGYDLRGISHDRLR-ETPLQWPCPPDGASNRSPIR
MAV_2075|M.avium_104 AEEVFEEIKRFWNPTTGYDLRGVSYERLR-RQPLQWPCPPQSTADRNPIR
MAB_2438|M.abscessus_ATCC_1997 SEEIFEEIRAFWNPRTGYDMRGMSYARLR-QGPVQWPCPPESEVDRNPIR
MSMEG_2837|M.smegmatis_MC2_155 PDEAFEAWKRCSAGRP-CDYTGLSYEKLRGSGGIQWPCNAEHPDGVERLY
Mb0203|M.bovis_AF2122/97 KLTAYVLYETLGPTLPDGLAGAAALWGLAQKTAMAYPDAVRRAGHADGNA
Rv0197|M.tuberculosis_H37Rv KLTAYVLYETLGPTLPDGLAGAAALWGLAQKTAMAYPDAVRRAGHADGNA
Mflv_3016|M.gilvum_PYR-GCK YLNDGVSQDLHIDDDG---------HIPRLAFATPSRRAVFHPRPHLDAA
Mvan_3491|M.vanbaalenii_PYR-1 YLNDGVSQDQYVGPDG---------HRPRLAFPTPSRRAVFHPRPHMDAA
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M YLNDGVSQLQFVRADG---------TVPRLAFPTATGRAVFFARPHLVPD
MUL_1474|M.ulcerans_Agy99 YLNDGVSQLQFVRADG---------TVPRLAFPTATGRAVFFARPHLVPD
MAV_2075|M.avium_104 YLNDGVSQTQLVREDG---------TVPRLAFPTPSGRAVFFARPHLQPE
MAB_2438|M.abscessus_ATCC_1997 YLNDGISQHPHVDENG---------VVPRLAFPTPSRRAVFHARAHRDPA
MSMEG_2837|M.smegmatis_MC2_155 AGGEFFAAPDYCEAYGKDLITGAPLEPTEYRAMNPFGKAIIKAAEYVPPH
Mb0203|M.bovis_AF2122/97 LFDAILERPSGVTFTVHN-------YEDDFALISHPDHKIALEIPEMLAE
Rv0197|M.tuberculosis_H37Rv LFDAILERPSGVTFTVHN-------YEDDFALISHPDHKIALEIPEMLAE
Mflv_3016|M.gilvum_PYR-GCK ELPDDDYPFILNTGRLQHQWHTMTKTG-------RVAKLTKLNPAPFVEI
Mvan_3491|M.vanbaalenii_PYR-1 ELPDDDYPLVLNTGRLQHQWHTMTKTG-------KVAKLNKLNPGPFVEI
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M EMPDGDYPFLLNTGRLAHQWHTLTKTG-------KIAKLNKLNPGPFVEV
MUL_1474|M.ulcerans_Agy99 EMPDGDYPFLLNTGRLAHQWHTLTKTG-------KIAKLNKLNPGPFVEV
MAV_2075|M.avium_104 EMPDDDYPFLLNTGRLPHQWHTMTKTG-------KVAKLNKLNPGPFVEI
MAB_2438|M.abscessus_ATCC_1997 ELPGEGYPVVLNTGRLQHHWHTLTKTG-------RIKTLDRLHPSPFVEI
MSMEG_2837|M.smegmatis_MC2_155 ERPSAEYPCVLITGRTVYHFHTRTKTG-------RTPQLQAAAPEVWVEL
Mb0203|M.bovis_AF2122/97 IRSLTQTPSRLTTPQLPIVLSVGERRAYTANDIFRDPSWRKRDANGALRV
Rv0197|M.tuberculosis_H37Rv IRSLTQTPSRLTTPQLPIVLSVGERRAYTANDIFRDPSWRKRDANGALRV
Mflv_3016|M.gilvum_PYR-GCK HPSDAAALGITDGQDLELRTRRGRAVLPAVLTERVRPGNTWAPFHWN---
Mvan_3491|M.vanbaalenii_PYR-1 HPDDAAALGISGGHDVELVTRRGRAVLPAVLTDRVQPGNTWVPFHWN---
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M HPDDAADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWN---
MUL_1474|M.ulcerans_Agy99 HPDDAADMQICEGDHIEIASRRGRAVLPVVITDRVRPGNCFAPFHWN---
MAV_2075|M.avium_104 HPDDAARLGIGEHDRVEIASRRGRAVLPAVVSDRVRPGNCFAPFHWN---
MAB_2438|M.abscessus_ATCC_1997 HPHDATTLGISDGDIVEIASRRGTAELPALVSDRVKRGSCFAPFHWN---
MSMEG_2837|M.smegmatis_MC2_155 ARADALRAGIVEGDLVEIRTVRGCVTAAARLTD-LRRGVVFLPFHYGYWD
Mb0203|M.bovis_AF2122/97 SVEDAQALGLADGCLARITTAAGSAEATVEVTETMLAGHAALPNGFG---
Rv0197|M.tuberculosis_H37Rv SVEDAQALGLADGCLARITTAAGSAEATVEVTETMLAGHAALPNGFG---
Mflv_3016|M.gilvum_PYR-GCK -----DEHGENLTINALTNDAVDPDSLQPEFKVCAVRLTPVPAADGAPDL
Mvan_3491|M.vanbaalenii_PYR-1 -----DEHGDHLTVNALTNDAVDPDSLQPEFKVCAVRLAPVPAAG-APEF
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M -----DAFGEYLSINAVTNDAVDPISRQPEYKACAVTLTKVARPQLQPEP
MUL_1474|M.ulcerans_Agy99 -----DAFGEYLSINAVTNDAVDPISRQPEYKACAVTLTKVARPQLQPEP
MAV_2075|M.avium_104 -----DAFGEYLSINAVTNDAVDPISNQPEFKACAVTLTKVAVSHPDSAI
MAB_2438|M.abscessus_ATCC_1997 -----DAHGPGLTINAVTNDAVDPDSLQPEFKVSAVALRPTGRTKADSMP
MSMEG_2837|M.smegmatis_MC2_155 TGDDGGKDGHHRAANELTLTDWDPVSKQPIFKTAAASVR-----------
Mb0203|M.bovis_AF2122/97 --LDYTGDDGRTVVAGVAPNALTSTRWRDPYAG-----------------
Rv0197|M.tuberculosis_H37Rv --LDYTGDDGRTVVAGVAPNALTSTRWRDPYAG-----------------
Mflv_3016|M.gilvum_PYR-GCK T------------------------------------------------D
Mvan_3491|M.vanbaalenii_PYR-1 T------------------------------------------------E
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M GEPADTCADATAPKLLADTAQFSVTQVDALAELLGVANEPTPQFGPFARS
MUL_1474|M.ulcerans_Agy99 GEPADACADATAPKLLADTAQFSVTQVDALAELLGVGNEPTPQFGPSARS
MAV_2075|M.avium_104 G-TGPSAGHDTPESAPTEVREISVSQVDALGELLGVATSFKPEFNELGRS
MAB_2438|M.abscessus_ATCC_1997 E-----------------------KQKEALGD------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK DEKLYIAGFLAGVDEGRPGVPVLPAGAPVGARARLWVDGLLAGRYSRLET
Mvan_3491|M.vanbaalenii_PYR-1 TEKLYLAGFFAGIEEGLPGVPVLPASAPVGPRARLWVDGLLAGRYSRSDT
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M YLAGLIAGLRSETGRRMAGVPTLPVSSPFDTGTRLWLDGLLAGMFARAET
MUL_1474|M.ulcerans_Agy99 YLAGLIAGLRSETGRRMAGVSTLPISSPFDTGTRLWLDGLLAGMFARAET
MAV_2075|M.avium_104 YLAGMLTGLRSDVGRRAGGVPTLPPSAPFDSRTRLWVDGLLAGLFSRADA
MAB_2438|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK AAPS----------------------ASPRGGPLVLWASQTGTAEEFAGS
Mvan_3491|M.vanbaalenii_PYR-1 VAET----------------------PATEG-PLVLWASQTGNAEEFAGR
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M PPALPFPQTPGAAAQSDNAAEA----AVEQPPIVVLWASQTGTAEELAAS
MUL_1474|M.ulcerans_Agy99 PPALPFPQTPGAAAQSDNAAEA----AVEQPPIVVLWASQTGTAEELAAS
MAV_2075|M.avium_104 SQQAALPEPPQPAAQQPPAAPAGATPAPERAPVVVLWASQTGNAEELAAD
MAB_2438|M.abscessus_ATCC_1997 --------------------------------VAILWTSQTGNAETAAVS
MSMEG_2837|M.smegmatis_MC2_155 ----------------------------------RIGAGMAATPEPVAHA
Mb0203|M.bovis_AF2122/97 ----------------------------------TPWHKHVPAAIRRADA
Rv0197|M.tuberculosis_H37Rv ----------------------------------TPWHKHVPAAIRRADA
Mflv_3016|M.gilvum_PYR-GCK LGERLAGARL----RAMDDTDLSELSDAGEVVIVTSTFGDGGPPDNGTAF
Mvan_3491|M.vanbaalenii_PYR-1 LGERLNGARL----RAMDDVELDDLSEAGEVVIVTSTFGDGGPPDNGAGF
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M VAAQLSAAELPVVLHGMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAF
MUL_1474|M.ulcerans_Agy99 VAAQLSAAELPVVLHGMDEFAVADLVSTQRLLLVTSTTGDGEPPDNGAAF
MAV_2075|M.avium_104 VAAQLAAAELPVALHSMDDFPAAELAATRELLLITSTTGDGDAPDNGSGL
MAB_2438|M.abscessus_ATCC_1997 VHRLLHTAGISATITAMDECDPADLVGVNTAVVIASSFGEGGPPDNGARF
MSMEG_2837|M.smegmatis_MC2_155 VADEHL--------------------------------------------
Mb0203|M.bovis_AF2122/97 ESPIW---------------------------------------------
Rv0197|M.tuberculosis_H37Rv ESPIWYPKWAILPARGVLA-------------------------------
Mflv_3016|M.gilvum_PYR-GCK WERLESADAPALDGVRYTVLGIGDRSYDNFCGHAKSLDTRLADLGATRML
Mvan_3491|M.vanbaalenii_PYR-1 WERLESPHAPSLDGVRYTVLGIGDRSYDNFCGHARSLDARLADLGATRML
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M WRELCAATAPSLAGTRYSVLALGDSNYADFCGHGRALDHRLAELGASRVT
MUL_1474|M.ulcerans_Agy99 WRELCAPTAPSLAGTRYSVLALGDSNYADFCGHGRALDHRLAELGASRIT
MAV_2075|M.avium_104 WRALTGDAAPRLGNTRYAVLALGDSNYDDFCGHGRKLDARLAELGATRIA
MAB_2438|M.abscessus_ATCC_1997 WAALSGDTKP-LNHMRYAVLGFGDRAYADFCGHAKALDARLHELGASPLL
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK DRADCEAYDEQPMAAWADSVVGLMSTPVTPAP----------------TQ
Mvan_3491|M.vanbaalenii_PYR-1 DRVECEAYDAQPLARWADSVVELVAAPGTPP-------------------
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M DRVDCEPDYEESAARWLQEVLDGLRRTAPPV---------ITAAPVRAAS
MUL_1474|M.ulcerans_Agy99 DRVDCEPDYEESAARWLQEVLDGLRRTAPPV---------ITAEPVRAAS
MAV_2075|M.avium_104 ERVDCEPDYEQAAAKWVADVIEALTRTPTAVGGDGGATVSARTSPVAAPS
MAB_2438|M.abscessus_ATCC_1997 GRVDGEATDRTLVASWTADLLDAIGDGATAI---------VETVRKLRSE
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK PAVPAAPAPFTRGNPAQAPLCRNVRLTPDGAGKDVRQFGFDISGQDLAYS
Mvan_3491|M.vanbaalenii_PYR-1 AAPAQEPTLFTRAEPVAAPLCRNTRLTPQGAAKEVRQIGFDISAHDVTYS
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M IANR--PQGYTKKRPLLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYE
MUL_1474|M.ulcerans_Agy99 IASR--PQGYTKKRPLLTSVMRNTTLSRPRSAKDVRQLVFRVPEQTVSYE
MAV_2075|M.avium_104 RPNTPAPHTYSKKHPLITDMVRNTTLNGPKSTKDVRHLVFNLPEDAVSYE
MAB_2438|M.abscessus_ATCC_1997 GLRVAAPERFTRDAPILAALSHNELLSAPNSGKEVRRIEFDLTGHDVSYS
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK VGDSLGVWVVNSDAVVESWLSATGFHGAEAVIVDG-RQISLREALTRHYD
Mvan_3491|M.vanbaalenii_PYR-1 VGDSLGVCVVNSDFVVENWLAATDLRGDEAVVVDG-VQQALRDALTAHYD
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M AGDALGVWPRNAHQLVDEWLGVTQLDGHTEVEVAGHGTMSLRAALTDRFE
MUL_1474|M.ulcerans_Agy99 AGDALGVWPRNAHQLVDEWLGVTRLDGHTEVEVAGHGTMSLRAALTDRFE
MAV_2075|M.avium_104 AGDALGVWPRNSDELVDEWLAVTGLDGQTPVEVGEHGLMSLRSALTERIE
MAB_2438|M.abscessus_ATCC_1997 AGDALGIYPTNREEDVQRWLTTTGFDAQLPVTIDG-GELPLATALANHYD
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK VCKVTSNLVTFVAEHCPDA-----ATAKRLRNDRGALDTWLVDRNGLDLV
Mvan_3491|M.vanbaalenii_PYR-1 VCKVTSNLVKFVAEHCRDA-----ATAKRLRNDRGELDRWLVNRNGLDLV
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M IAHLSPDLLRFVAQRTLDSNTANQLAELMRPENKAALADWTWGRQSVDLL
MUL_1474|M.ulcerans_Agy99 IAHLSPDLLRFVAQRTLDSNTANQLAELMRPENKAALADWTWGRQSVDLL
MAV_2075|M.avium_104 IAHISRDLVRFVQERTGDA----KLAELLKPENKRALADWTWGRQSIDLL
MAB_2438|M.abscessus_ATCC_1997 ICRVTEDLLRFIAERRRDK----HSAKLLQGRDTQAREVWLRGRNALDVI
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK REFGIRADPALWQEVLVRLTPRQYSISSSPLVSPHEVQLTVSVVRYRGAD
Mvan_3491|M.vanbaalenii_PYR-1 REFSVRADPQLWQEVLVRLTPRQYSISSSPLVSPNEVQLTVSVVRYRGAD
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M AQSPVRASVDEWMSVLKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQ
MUL_1474|M.ulcerans_Agy99 AQSPVRASVDEWMSVLKPIQPRLYSISSSPKEHPGEVHLTVSPVRYN-FQ
MAV_2075|M.avium_104 AQLPVSASAHEWLRVLKRLQPRLYSISSSPKACPGEVHLTVSPVRYN-FQ
MAB_2438|M.abscessus_ATCC_1997 REFPIRAAIEEWQQVLIRLTPRQYSISSSPLVSPQAISLTVSIVRYQGPD
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK GTPRGGVASTYLADLPDCTPVPVFLQRSPHFRPPEDPHTPMIMVGPGTGI
Mvan_3491|M.vanbaalenii_PYR-1 GGPRGGVASTYLADLPDGTAVPVFLQRSPHFRPPQDSHTPMIMVGPGTGI
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M GVPRRGVCSTYLADRSPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGI
MUL_1474|M.ulcerans_Agy99 GVPRRGVCSTYLADRSPSDQIAIYVRKSSNFRPPSDPRTPMIMIGPGTGI
MAV_2075|M.avium_104 GVPRRGVCSTYLAARSPGDRVAVYLQPSSNFRPPSDPDTPMIMIGPGTGI
MAB_2438|M.abscessus_ATCC_1997 GSPRGGVGSTFLADRAQHLPVPIFLQRSPHFRPPRTSDTPMIMIGPGTGI
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK APFRGFLQERRALGHRGANWLFFGDQHREQNFYYRDDLLDMVDDGFLNRL
Mvan_3491|M.vanbaalenii_PYR-1 APFRGFLQERRALGHRGPNWLFFGDQHRAQNFYYRDDLQDMVDDGFLNRL
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M APFRGFLQERRALGHTGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNL
MUL_1474|M.ulcerans_Agy99 APFRGFLQERRALGHTGPNWLFFGEQHAATDFYYRDEIQAMHRDGLLTNL
MAV_2075|M.avium_104 APFRGFLQERRALGHRGPNWLFFGEQHAATDFYYRDELEQMREDGFLTEL
MAB_2438|M.abscessus_ATCC_1997 APFRGFLQERRALGHTGANWLFFGDQHRTEHFYYRDELDGFLRDGSLRRL
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK DLAFSRDQRQRIYVQHKMLDYGADVWRWLDDGAHFYVCGDATRMAKDVDD
Mvan_3491|M.vanbaalenii_PYR-1 DLAFSRDQARRVYVQHKMLDYGADVWRWLDDGAHFYVCGDATRMAGDVDD
TH_4553|M.thermoresistible__bu --------------------------------------------------
MMAR_3639|M.marinum_M DLAFSRDQRDKVYVQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDR
MUL_1474|M.ulcerans_Agy99 DLAFSRDQRDKVYVQHLMQQRGAQLWQWLQDGAQVYVCGTADPMAKDVDR
MAV_2075|M.avium_104 DLAFSRDQQHKVYVQHLMRNRGKQLWSWLQDGAQLYVCGTADPMAKDVDR
MAB_2438|M.abscessus_ATCC_1997 DLAFSRDQAKRIYVQHRMMEQGAQLWRWLNEGAHLYVCGDASRMAKDVDG
MSMEG_2837|M.smegmatis_MC2_155 --------------------------------------------------
Mb0203|M.bovis_AF2122/97 --------------------------------------------------
Rv0197|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3016|M.gilvum_PYR-GCK ALTEILRTHARMSSDAAREYKREMVAEKRYVRDVY
Mvan_3491|M.vanbaalenii_PYR-1 ALTEIIRTHGGMSADAARDYKREMVAEKRYVRDVY
TH_4553|M.thermoresistible__bu -----------------------------------
MMAR_3639|M.marinum_M MLCQIVAEHGGLDPESATAFVHALSADKRYHRDVY
MUL_1474|M.ulcerans_Agy99 MLCQIVAEHGGLDPESATAFVHALSADKRYHRDVY
MAV_2075|M.avium_104 ALCDIAAEFGNLDPDAAKAYVQSLSADKRYHRDVY
MAB_2438|M.abscessus_ATCC_1997 ALLTIAQKHGKLSGEQALEFRKELVAEKRYVRDVY
MSMEG_2837|M.smegmatis_MC2_155 -----------------------------------
Mb0203|M.bovis_AF2122/97 -----------------------------------
Rv0197|M.tuberculosis_H37Rv -----------------------------------