For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RIIVTGGNSGVGKATAAALAAAGHEVVIACRTLTKAHQAAADMAGDVEVAELDLADLTSVRKFADSVEFV DVLVNNAGVLGLPLTRTADGFEAHMGTNHLGHFALTCLLGDRIRNRVVVVASSNHALATMHFDDLNWHRR RYNPWSAYGESKLANMLFVQELTRRGRTAYASDPGMTATDITRDGSGLLQWAGRALSPRIAQSPADGARS TIQAVTTDLPSGTYIAPRGLFHQWGRPKPTKLIAKVRDPESARKLWDLSAELTGCDWQGANA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1968 | - | - | 100% (273) | retinol dehydrogenase 12 |
| M. avium 104 | MAV_2670 | - | e-101 | 85.31% (211) | retinol dehydrogenase 12 |
| M. avium 104 | MAV_1153 | - | 2e-58 | 45.72% (269) | retinol dehydrogenase 13 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0447c | - | 9e-51 | 43.31% (284) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1940 | - | 3e-58 | 46.89% (273) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0439c | - | 9e-51 | 43.31% (284) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00315 | - | 4e-46 | 41.84% (282) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1144c | - | 1e-55 | 44.07% (270) | short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_0757 | - | 1e-48 | 42.11% (285) | dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_5430 | - | 2e-60 | 47.23% (271) | retinol dehydrogenase 13 |
| M. thermoresistible (build 8) | TH_3199 | - | 5e-54 | 45.91% (281) | PUTATIVE retinol dehydrogenase 13 |
| M. ulcerans Agy99 | MUL_1391 | - | 6e-48 | 41.75% (285) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4786 | - | 3e-59 | 47.62% (273) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5430|M.smegmatis_MC2_155 -------MTQWTSADLPSFRGRTVVITGANSGLGLVTARELARVGAKVIV
TH_3199|M.thermoresistible__bu ---------MWTAADLPSFSDRTVIVTGANSGLGLVTARELARVGARVII
Mflv_1940|M.gilvum_PYR-GCK -------MSDWTAADLPSFAGRTVIVTGANSGLGLVTARELARVGATTIL
Mvan_4786|M.vanbaalenii_PYR-1 -------MSDWTAADLPSFAGRTVIVTGANSGLGLITARELARVGARTIL
MAB_1144c|M.abscessus_ATCC_199 ---MSKSTATWSAAKLPSFEGRTVIITGANSGLGLETARELARVGAHVIM
MAV_1968|M.avium_104 ---------------------MRIIVTGGNSGVGKATAAALAAAGHEVVI
Mb0447c|M.bovis_AF2122/97 MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVL
Rv0439c|M.tuberculosis_H37Rv MTANDNKTRKWSAADVPDQSGRVVVVTGANTGIGYHTAAVFADRGAHVVL
MMAR_0757|M.marinum_M MSANGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALAGRGAHVVL
MUL_1391|M.ulcerans_Agy99 MSAKGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAHVVL
MLBr_00315|M.leprae_Br4923 -------MAKWTTADIPDQTGRVAVITGANTGLGYQTALALAEHGAHVVL
::**.*:*:* ** :* * .::
MSMEG_5430|M.smegmatis_MC2_155 AVRNLDKGTAAAETMPG----GIVEVRKLDLQDLASVHEFADTVE----T
TH_3199|M.thermoresistible__bu AVRNTTKGEAAAEQMTGPG-HGPVEVRALDLQNLASVREFAAGVEG---D
Mflv_1940|M.gilvum_PYR-GCK AVRNLDKGRAAADSMSG-----DVEVRRLDLQDLSSVREFADGVD----S
Mvan_4786|M.vanbaalenii_PYR-1 AVRNLDKGNTAAATMTG-----DVEVRSLDLQNLASVRAFADGVD----S
MAB_1144c|M.abscessus_ATCC_199 AVRNTEKGNAAQASIKG-----STEVRQVDVADLASVRAFADTVE----G
MAV_1968|M.avium_104 ACRTLTKAHQAAADMAG-----DVEVAELDLADLTSVRKFADSVE----F
Mb0447c|M.bovis_AF2122/97 AVRNLEKGNAARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPR
Rv0439c|M.tuberculosis_H37Rv AVRNLEKGNAARARIMAARPGAHVTLQQLDLCSLDSVRAAADALRTAYPR
MMAR_0757|M.marinum_M AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MUL_1391|M.ulcerans_Agy99 AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MLBr_00315|M.leprae_Br4923 AVRNLDKGKDAAARITATSAQNNVALQELDLASLESVRAAAKQLRSDYDH
* *. *. * : . . : :*: .* **: * :
MSMEG_5430|M.smegmatis_MC2_155 VDVLVNNAGIMAVPLARTVDGFESQIGTNHLGHFALTNLLLPKIS----D
TH_3199|M.thermoresistible__bu VDVLVNNAGIMAVPLARTVDGFESQIGTNHLGHFALTNLLLPQIT----D
Mflv_1940|M.gilvum_PYR-GCK VDVLVNNAGIMAVPYALTADGFESQIGTNHLGHFALTNLLLPKIS----D
Mvan_4786|M.vanbaalenii_PYR-1 VDVLVNNAGIMAVPYAQTVDGFESQIGTNHLGHFALTNLLLPKIS----D
MAB_1144c|M.abscessus_ATCC_199 ADILVNNAGIMMVPPAKTVDGFESQIGTNHLGAFALTNLLLPKLT----D
MAV_1968|M.avium_104 VDVLVNNAGVLGLPLTRTADGFEAHMGTNHLGHFALTCLLGDRIR----N
Mb0447c|M.bovis_AF2122/97 IDVLINNAGVMWTPKQVTKDGFELQFGTNHLGHFALTGLVLDHMLPVPGS
Rv0439c|M.tuberculosis_H37Rv IDVLINNAGVMWTPKQVTKDGFELQFGTNHLGHFALTGLVLDHMLPVPGS
MMAR_0757|M.marinum_M IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MUL_1391|M.ulcerans_Agy99 IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MLBr_00315|M.leprae_Br4923 IDLLINNAGVMWTPKSTTKDGFELQFGTNHLGHFAFTGLLLDRLLPIVGS
*:*:****:: * * **** ::****** **:* *: :: .
MSMEG_5430|M.smegmatis_MC2_155 RVVTVSSMMH-WIGRINLRDLNWKARPYSAWLAYGQSKLANLMFTSELQR
TH_3199|M.thermoresistible__bu RVVTVSSLMH-WFGYLSLNDLNWKARPYSAWLAYAQSKLANLLFTSELQR
Mflv_1940|M.gilvum_PYR-GCK RVVTVSSMMH-LFGRINLNDLNWKSRPYLAWPAYGQSKLANLLFTSELQR
Mvan_4786|M.vanbaalenii_PYR-1 RVVTVSSMMH-LMGRVNLKDLNWKSRPYLAWPAYGQSKLANLLFTGELQR
MAB_1144c|M.abscessus_ATCC_199 RVIAVSSVAH-RAGKIDLTDLNYERRRYTRAGAYGASKLANLLFTKELQR
MAV_1968|M.avium_104 RVVVVASSNH-ALATMHFDDLNWHRRRYNPWSAYGESKLANMLFVQELTR
Mb0447c|M.bovis_AF2122/97 RVVTVSSQGHRIHAAIHFDDLQWERR-YNRVAAYGQAKLANLLFTYELQR
Rv0439c|M.tuberculosis_H37Rv RVVTVSSQGHRIHAAIHFDDLQWERR-YNRVAAYGQAKLANLLFTYELQR
MMAR_0757|M.marinum_M RVITVSSLGHRIRAAIHFDDLQWERS-YNRVAAYGQSKLANLLFTYELQR
MUL_1391|M.ulcerans_Agy99 RVITVSSLGHRIRAAIHFDDLQWERS-YNRVAAYGQSKLANLLFTYELQR
MLBr_00315|M.leprae_Br4923 RVITVSSLSHRLFADIHFNDLQWECN-YNRVAAYGQSKLANLLFTYELQR
**:.*:* * . : : **::. * **. :****::*. ** *
MSMEG_5430|M.smegmatis_MC2_155 RLV-ASGSSVRALAAHPGYSATNLQGHSGNRFGTAAAALGNRHLATDVTF
TH_3199|M.thermoresistible__bu RLD-TVGSPVRAVAAHPGYSSTNLQGHTGRRFGDALARIGNRYLATDAEF
Mflv_1940|M.gilvum_PYR-GCK RLS-RAGSPVRAVAAHPGYSATNLQGHSGNPLGEKIARAGNR-MATDADF
Mvan_4786|M.vanbaalenii_PYR-1 RLA-AAGSPVRAVAAHPGYSATNLQGHSGNPLGEKIARAGNR-IATDADF
MAB_1144c|M.abscessus_ATCC_199 RLS-AAGSPVRALTVHPGVAATELQSHSGNPIFELALKTGNL-FAQNAAH
MAV_1968|M.avium_104 RGR-T------AYASDPGMTATDIT-RDGSGLLQWAGRALSPRIAQSPAD
Mb0447c|M.bovis_AF2122/97 RLG-EAGKSTIAVAAHPGGSNTELT-RNLPRLIRPVATVLGPLLFQSPEM
Rv0439c|M.tuberculosis_H37Rv RLG-EAGKSTIAVAAHPGGSNTELT-RNLPRLIRPVATVLGPLLFQSPEM
MMAR_0757|M.marinum_M RLAADSQAATIAVAAHPGGSNTELA-RNLPRMLVPLANILGPALFQSAQM
MUL_1391|M.ulcerans_Agy99 RLAADSQAATIAVAAHPGDSNTELA-RNLPRMLVPLANILGPALFQSAQM
MLBr_00315|M.leprae_Br4923 RLA--TRQTTIAVAAHPGGSRTELT-RTLPALIAPIFSVAELFLTQDAAT
* * : .** : *:: : : : .
MSMEG_5430|M.smegmatis_MC2_155 GARQTLYAVSQ-DLPGDTFVGPR--FGQWGPTGSVGRSPLARRTDTQRAL
TH_3199|M.thermoresistible__bu GARQTLYAVAR-DVPGDSFIGPR--FAMHGPTEQVGRSPLARSAGTARAL
Mflv_1940|M.gilvum_PYR-GCK GARQTLYAVAR-DVAGDSFIGPR--FTMFGPTVTTWRSPLARNRTTAAQL
Mvan_4786|M.vanbaalenii_PYR-1 GARQTLYAVAA-DIPGDSFIGPR--FSMFGPTVATWRSPLARDRGKAAGL
MAB_1144c|M.abscessus_ATCC_199 GALPTLYAASQ-DLPGDTYIGPDGPFEAKGYPTRVGRSGRAQDTETAKGL
MAV_1968|M.avium_104 GARSTIQAVTT-DLPSGTYIAPRGLFHQWGRPKPTKLIAKVRDPESARKL
Mb0447c|M.bovis_AF2122/97 GALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRL
Rv0439c|M.tuberculosis_H37Rv GALPTLRAATDPTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRL
MMAR_0757|M.marinum_M GALPTLRAATDPSVAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRL
MUL_1391|M.ulcerans_Agy99 GALPTLRTATDPSAAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRL
MLBr_00315|M.leprae_Br4923 GALPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSHDVDRQLRL
** *: :.: .. : .* * . . : *
MSMEG_5430|M.smegmatis_MC2_155 WELSEQLTGTTYPL---
TH_3199|M.thermoresistible__bu WELSEQLTDTKFPL---
Mflv_1940|M.gilvum_PYR-GCK WTLSEQLTGVEFPL---
Mvan_4786|M.vanbaalenii_PYR-1 WTLSEQLTGTEFPL---
MAB_1144c|M.abscessus_ATCC_199 WRLSEQLTGVSFPL---
MAV_1968|M.avium_104 WDLSAELTGCDWQGANA
Mb0447c|M.bovis_AF2122/97 WTVSEELTGVSFGV---
Rv0439c|M.tuberculosis_H37Rv WTVSEELTGVSFGV---
MMAR_0757|M.marinum_M WTVSEELTGVSFPV---
MUL_1391|M.ulcerans_Agy99 WTVSEELTGVSFPV---
MLBr_00315|M.leprae_Br4923 WAVSEELTGVVYPVG--
* :* :**. :