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M. thermoresistible (build 8) TH_3199 (-)

annotation: retinol dehydrogenase 13
coordinates: 1818988 - 1819866
length: 293

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3199--100% (293)retinol dehydrogenase 13
M. thermoresistible (build 8)TH_4179-3e-5343.42% (304) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_1257-1e-1331.50% (200) short chain dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0069-8e-5645.87% (303) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1940-1e-12076.63% (291) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv0068-2e-5545.54% (303) short chain dehydrogenase
M. leprae Br4923MLBr_00315-8e-5344.22% (303) short chain dehydrogenase
M. abscessus ATCC 19977MAB_1144c-1e-8759.73% (293) short-chain dehydrogenase/reductase
M. marinum MMMAR_0757-7e-5345.63% (309) dehydrogenase/reductase
M. avium 104MAV_4124-1e-11471.63% (289) dehydrogenase
M. smegmatis MC2 155MSMEG_5430-1e-12577.66% (291) retinol dehydrogenase 13
M. ulcerans Agy99MUL_1391-2e-5245.31% (309) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_4786-1e-12076.29% (291) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


TH_3199|M.thermoresistible__bu      ---------MWTAADLPSFSDRTVIVTGANSGLGLVTARELARVGARVII
MSMEG_5430|M.smegmatis_MC2_155      -------MTQWTSADLPSFRGRTVVITGANSGLGLVTARELARVGAKVIV
Mflv_1940|M.gilvum_PYR-GCK          -------MSDWTAADLPSFAGRTVIVTGANSGLGLVTARELARVGATTIL
Mvan_4786|M.vanbaalenii_PYR-1       -------MSDWTAADLPSFAGRTVIVTGANSGLGLITARELARVGARTIL
MAV_4124|M.avium_104                -------MPDWTAAQLPSFAGRTVIVTGANAGLGEVTARELARVGGHVIL
MAB_1144c|M.abscessus_ATCC_199      ---MSKSTATWSAAKLPSFEGRTVIITGANSGLGLETARELARVGAHVIM
Mb0069|M.bovis_AF2122/97            -------MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVL
Rv0068|M.tuberculosis_H37Rv         -------MTKWTAADIPDQTGRTAVITGANTGLGFETAAALAAHGAHVVL
MLBr_00315|M.leprae_Br4923          -------MAKWTTADIPDQTGRVAVITGANTGLGYQTALALAEHGAHVVL
MMAR_0757|M.marinum_M               MSANGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALAGRGAHVVL
MUL_1391|M.ulcerans_Agy99           MSAKGKAKSHWSASDIPDQSGRVVVVTGANTGLGYHTAEALADRGAHVVL
                                              *:::.:*.  .*..::****:***  **  **  *. .::

TH_3199|M.thermoresistible__bu      AVRNTTKGEAAAEQMTGPG-HGPVEVRALDLQNLASVREFAAGVEG---D
MSMEG_5430|M.smegmatis_MC2_155      AVRNLDKGTAAAETMPG----GIVEVRKLDLQDLASVHEFADTVE----T
Mflv_1940|M.gilvum_PYR-GCK          AVRNLDKGRAAADSMSG-----DVEVRRLDLQDLSSVREFADGVD----S
Mvan_4786|M.vanbaalenii_PYR-1       AVRNLDKGNTAAATMTG-----DVEVRSLDLQNLASVRAFADGVD----S
MAV_4124|M.avium_104                AVRNTDKGRAAADRMAGVA-TGRVEVRELDLQDLASVRRFADGID----T
MAB_1144c|M.abscessus_ATCC_199      AVRNTEKGNAAQASIKG-----STEVRQVDVADLASVRAFADTVE----G
Mb0069|M.bovis_AF2122/97            AVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQR
Rv0068|M.tuberculosis_H37Rv         AVRNLDKGKQAAARITEATPGAEVELQELDLTSLASVRAAAAQLKSDHQR
MLBr_00315|M.leprae_Br4923          AVRNLDKGKDAAARITATSAQNNVALQELDLASLESVRAAAKQLRSDYDH
MMAR_0757|M.marinum_M               AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
MUL_1391|M.ulcerans_Agy99           AVRNPEKGNAAVAQIVAAKPQADVTLQALDLSSLDSVRSAADALRSAYPR
                                    ****  **  *   :        . :: :*: .* **:  *  :      

TH_3199|M.thermoresistible__bu      VDVLVNNAGIMAVPLARTVDGFESQIGTNHLGHFALTNLLLPQIT----D
MSMEG_5430|M.smegmatis_MC2_155      VDVLVNNAGIMAVPLARTVDGFESQIGTNHLGHFALTNLLLPKIS----D
Mflv_1940|M.gilvum_PYR-GCK          VDVLVNNAGIMAVPYALTADGFESQIGTNHLGHFALTNLLLPKIS----D
Mvan_4786|M.vanbaalenii_PYR-1       VDVLVNNAGIMAVPYAQTVDGFESQIGTNHLGHFALTNLLLPKIS----D
MAV_4124|M.avium_104                VDVLVNNAGIMATKHAVTVDGFEGQIGTNHLGHFALTNLLLPKLT----D
MAB_1144c|M.abscessus_ATCC_199      ADILVNNAGIMMVPPAKTVDGFESQIGTNHLGAFALTNLLLPKLT----D
Mb0069|M.bovis_AF2122/97            IDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGS
Rv0068|M.tuberculosis_H37Rv         IDLLINNAGVMYTPRQTTADGFEMQFGTNHLGHFALTGLLIDRLLPVAGS
MLBr_00315|M.leprae_Br4923          IDLLINNAGVMWTPKSTTKDGFELQFGTNHLGHFAFTGLLLDRLLPIVGS
MMAR_0757|M.marinum_M               IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
MUL_1391|M.ulcerans_Agy99           IDLLINNAGVMWTPKQVTKDGFEMQFGTNHLGHFALTGLLLDHLLPVPGS
                                     *:*:****:* .    * **** *:****** **:*.**: ::     .

TH_3199|M.thermoresistible__bu      RVVTVSSLMHWF-GYLSLNDLNWKARPYSAWLAYAQSKLANLLFTSELQR
MSMEG_5430|M.smegmatis_MC2_155      RVVTVSSMMHWI-GRINLRDLNWKARPYSAWLAYGQSKLANLMFTSELQR
Mflv_1940|M.gilvum_PYR-GCK          RVVTVSSMMHLF-GRINLNDLNWKSRPYLAWPAYGQSKLANLLFTSELQR
Mvan_4786|M.vanbaalenii_PYR-1       RVVTVSSMMHLM-GRVNLKDLNWKSRPYLAWPAYGQSKLANLLFTGELQR
MAV_4124|M.avium_104                RVVTVSSLMHHF-GYISLKDLNFRSRPYSAWLAYSQSKLANLLFTSELQR
MAB_1144c|M.abscessus_ATCC_199      RVIAVSSVAHRA-GKIDLTDLNYERRRYTRAGAYGASKLANLLFTKELQR
Mb0069|M.bovis_AF2122/97            RVVTISSVGHRIRAAIHFDDLQWERR-YRRVAAYGQAKLANLLFTYELQR
Rv0068|M.tuberculosis_H37Rv         RVVTISSVGHRIRAAIHFDDLQWERR-YRRVAAYGQAKLANLLFTYELQR
MLBr_00315|M.leprae_Br4923          RVITVSSLSHRLFADIHFNDLQWECN-YNRVAAYGQSKLANLLFTYELQR
MMAR_0757|M.marinum_M               RVITVSSLGHRIRAAIHFDDLQWERS-YNRVAAYGQSKLANLLFTYELQR
MUL_1391|M.ulcerans_Agy99           RVITVSSLGHRIRAAIHFDDLQWERS-YNRVAAYGQSKLANLLFTYELQR
                                    **:::**: *   . : : **::.   *    **. :*****:** ****

TH_3199|M.thermoresistible__bu      RLDTVG-SPVRAVAAHPGYSSTNLQGHTGRRFGDALARIGNRYLATDAEF
MSMEG_5430|M.smegmatis_MC2_155      RLVASG-SSVRALAAHPGYSATNLQGHSGNRFGTAAAALGNRHLATDVTF
Mflv_1940|M.gilvum_PYR-GCK          RLSRAG-SPVRAVAAHPGYSATNLQGHSGNPLGEKIARAGNR-MATDADF
Mvan_4786|M.vanbaalenii_PYR-1       RLAAAG-SPVRAVAAHPGYSATNLQGHSGNPLGEKIARAGNR-IATDADF
MAV_4124|M.avium_104                RLDAVP-SSLRALAAHPGWSHTNLQGNSGRKLGDAAVLAVDRIVSTDADF
MAB_1144c|M.abscessus_ATCC_199      RLSAAG-SPVRALTVHPGVAATELQSHSGNPIFELALKTGNL-FAQNAAH
Mb0069|M.bovis_AF2122/97            RLAPG--GTTIAVASHPGVSNTELVRNMPRPLVAVAAILAP--LMQDAEL
Rv0068|M.tuberculosis_H37Rv         RLAPG--GTTIAVASHPGVSNTEVVRNMPRPLVAVAAILAP--LMQDAEL
MLBr_00315|M.leprae_Br4923          RLATR--QTTIAVAAHPGGSRTELTRTLPALIAPIFSVAELF-LTQDAAT
MMAR_0757|M.marinum_M               RLAADSQAATIAVAAHPGGSNTELARNLPRMLVPLANILGPA-LFQSAQM
MUL_1391|M.ulcerans_Agy99           RLAADSQAATIAVAAHPGDSNTELARNLPRMLVPLANILGPA-LFQSAQM
                                    **      .  *:: *** : *::       :           .  ..  

TH_3199|M.thermoresistible__bu      GARQTLYAVAR-DVPGDSFIGPR--FAMHGPTEQVGRSPLARSAGTARAL
MSMEG_5430|M.smegmatis_MC2_155      GARQTLYAVSQ-DLPGDTFVGPR--FGQWGPTGSVGRSPLARRTDTQRAL
Mflv_1940|M.gilvum_PYR-GCK          GARQTLYAVAR-DVAGDSFIGPR--FTMFGPTVTTWRSPLARNRTTAAQL
Mvan_4786|M.vanbaalenii_PYR-1       GARQTLYAVAA-DIPGDSFIGPR--FSMFGPTVATWRSPLARDRGKAAGL
MAV_4124|M.avium_104                GARQTLYAVSQ-DLPGDTFVGPR--FGLYGRTQPTWRNWPAKRAGTAAAL
MAB_1144c|M.abscessus_ATCC_199      GALPTLYAASQ-DLPGDTYIGPDGPFEAKGYPTRVGRSGRAQDTETAKGL
Mb0069|M.bovis_AF2122/97            GALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRL
Rv0068|M.tuberculosis_H37Rv         GALPTLRAATDPAVRGGQYFGPDGFGEIRGYPKVVASSAQSHDEQLQRRL
MLBr_00315|M.leprae_Br4923          GALPTLRAATDAAVLGGQYFGPDGFAEIRGHPKVVASNGKSHDVDRQLRL
MMAR_0757|M.marinum_M               GALPTLRAATDPSVAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRL
MUL_1391|M.ulcerans_Agy99           GALPTLRTATDPSAAGGQYYGPDGFAEQRGHPKIVQSSAQSHDEDLQRRL
                                    **  ** :.:     *. : **       * .  .  .  ::       *

TH_3199|M.thermoresistible__bu      WELSEQLTDTKFPL------------------------------------
MSMEG_5430|M.smegmatis_MC2_155      WELSEQLTGTTYPL------------------------------------
Mflv_1940|M.gilvum_PYR-GCK          WTLSEQLTGVEFPL------------------------------------
Mvan_4786|M.vanbaalenii_PYR-1       WTLSEQLTGTEFPL------------------------------------
MAV_4124|M.avium_104                WELSEELTGTSFRSDPDLRRGRAAGPPSPRRPPGAVTKLVLSATPRGVGG
MAB_1144c|M.abscessus_ATCC_199      WRLSEQLTGVSFPL------------------------------------
Mb0069|M.bovis_AF2122/97            WAVSEELTGVVYPVG-----------------------------------
Rv0068|M.tuberculosis_H37Rv         WAVSEELTGVVYPVG-----------------------------------
MLBr_00315|M.leprae_Br4923          WAVSEELTGVVYPVG-----------------------------------
MMAR_0757|M.marinum_M               WTVSEELTGVSFPV------------------------------------
MUL_1391|M.ulcerans_Agy99           WTVSEELTGVSFPV------------------------------------
                                    * :**:**.. :                                      

TH_3199|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5430|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1940|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4786|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4124|M.avium_104                YAMSDANLAAVLALCAALASAVGNVVRQRSAQEVTDKPVGHLALFGMLLR
MAB_1144c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0069|M.bovis_AF2122/97            --------------------------------------------------
Rv0068|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_00315|M.leprae_Br4923          --------------------------------------------------
MMAR_0757|M.marinum_M               --------------------------------------------------
MUL_1391|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_3199|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5430|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1940|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4786|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4124|M.avium_104                DTRWWLGGLGDIGSYVLLAAALDRGSVLLVMSLQVTALLFALPIYARMTH
MAB_1144c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0069|M.bovis_AF2122/97            --------------------------------------------------
Rv0068|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_00315|M.leprae_Br4923          --------------------------------------------------
MMAR_0757|M.marinum_M               --------------------------------------------------
MUL_1391|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_3199|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5430|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1940|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4786|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4124|M.avium_104                HPITGREWAWALLLAVALAVLIAVGDPTGGQQRAPLQTWLVVAAVIGPLL
MAB_1144c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0069|M.bovis_AF2122/97            --------------------------------------------------
Rv0068|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_00315|M.leprae_Br4923          --------------------------------------------------
MMAR_0757|M.marinum_M               --------------------------------------------------
MUL_1391|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_3199|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5430|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1940|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4786|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4124|M.avium_104                VLGLLGARVWADRPVAALLLAAVAGSLLAMFAVLMKGVVDILEHNPGQLW
MAB_1144c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0069|M.bovis_AF2122/97            --------------------------------------------------
Rv0068|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_00315|M.leprae_Br4923          --------------------------------------------------
MMAR_0757|M.marinum_M               --------------------------------------------------
MUL_1391|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_3199|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5430|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1940|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4786|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4124|M.avium_104                RSFELYALVFCGVAGMIYHQSAYRAGALTASLPTIIVAKPVVGGILGIIV
MAB_1144c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0069|M.bovis_AF2122/97            --------------------------------------------------
Rv0068|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_00315|M.leprae_Br4923          --------------------------------------------------
MMAR_0757|M.marinum_M               --------------------------------------------------
MUL_1391|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_3199|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5430|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1940|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4786|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_4124|M.avium_104                LRETLVAGGWEWVVLAVTAVVVIVATVGLARGEAASMSAGAGRDVRPTDR
MAB_1144c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0069|M.bovis_AF2122/97            --------------------------------------------------
Rv0068|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_00315|M.leprae_Br4923          --------------------------------------------------
MMAR_0757|M.marinum_M               --------------------------------------------------
MUL_1391|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_3199|M.thermoresistible__bu      -------
MSMEG_5430|M.smegmatis_MC2_155      -------
Mflv_1940|M.gilvum_PYR-GCK          -------
Mvan_4786|M.vanbaalenii_PYR-1       -------
MAV_4124|M.avium_104                PKAASQA
MAB_1144c|M.abscessus_ATCC_199      -------
Mb0069|M.bovis_AF2122/97            -------
Rv0068|M.tuberculosis_H37Rv         -------
MLBr_00315|M.leprae_Br4923          -------
MMAR_0757|M.marinum_M               -------
MUL_1391|M.ulcerans_Agy99           -------