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NLQYNLMFPMRAVKHWQRWSEGASLGEVAKVVENAGFHGFSMSEHPFPDKDWLAHGGHHAFDPFVSLSFA AAATTRLRLMTYILVSGYRSPYLTAKAAASFDLLSGGRFTLGTGAGYLKPEFEALGADFHRRGALLDEAI AAWKATWAGDEHHGPEFGVAGHLALPLPVTAGGPPIWIGGNSKAARRRVVETANGWIPMGQSGEMATITR TPPLEDIARLASLISEVNKQRAERGRDAADVSFVPFEADKLVSGDCGDFIESVKPRLAEYAEAGVTWITV EPASRTFSDFRADVELMATELVEAPWVSRRLGLLDSDQGLVGPVCIVERGFELRGWDVAEVAVQAAGVVP VDPTEGGEFYVLDGLPRSASSRPVDQLGLVVTVDCLRESVIETISNGPN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1888 | - | - | 100% (400) | hypothetical protein MAV_1888 |
| M. avium 104 | MAV_2605 | - | e-137 | 75.75% (301) | hypothetical protein MAV_2605 |
| M. avium 104 | MAV_5129 | - | 7e-57 | 37.13% (307) | hypothetical protein MAV_5129 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 1e-21 | 34.20% (193) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_4097 | - | 9e-56 | 41.49% (282) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 1e-21 | 34.20% (193) | hypothetical protein Rv3079c |
| M. leprae Br4923 | MLBr_00131 | - | 6e-09 | 24.67% (227) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 2e-26 | 38.27% (196) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_0393 | - | 3e-56 | 41.34% (283) | hypothetical protein MMAR_0393 |
| M. smegmatis MC2 155 | MSMEG_4820 | - | 3e-51 | 39.50% (281) | hypothetical protein MSMEG_4820 |
| M. thermoresistible (build 8) | TH_2146 | - | 1e-59 | 40.85% (306) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1043 | - | 2e-55 | 43.40% (265) | hypothetical protein MUL_1043 |
| M. vanbaalenii PYR-1 | Mvan_2248 | - | 2e-55 | 40.78% (282) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 -----------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAEHTHI
Rv3079c|M.tuberculosis_H37Rv -----------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAEHTHI
Mflv_4097|M.gilvum_PYR-GCK ---MQFAITHPMHSHPYNPELVTGAGIARVAVAAEKAGFGGFGFTDH---
Mvan_2248|M.vanbaalenii_PYR-1 ---MQFAITHPMHSHPYNPELVTGTGIAQVAQAAEKAGFGGFGFTDH---
MMAR_0393|M.marinum_M ---MRFIITHPMHSHPYHPELASGAGVAAVAAAAERAGFHGFGFTDH---
MUL_1043|M.ulcerans_Agy99 -----------MHSHPYHPELASGAGVAAVAAAAERAGFHGFGFTDH---
MSMEG_4820|M.smegmatis_MC2_155 ---MRYSITHPMHSHPYHPDLVSGSGVVAVAAAAEAAGFDGFGFTDH---
TH_2146|M.thermoresistible__bu ---MRFAFTYPMDSHPYHPDLATGAAVARVAATAETAGFSGFGFTDH---
MAV_1888|M.avium_104 -MNLQYNLMFPMRAVKHWQRWSEGASLGEVAKVVENAGFHGFSMSEH---
MAB_0366|M.abscessus_ATCC_1997 -------MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVEHAVV
MLBr_00131|M.leprae_Br4923 MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALVPR
: . : .
Mb3106c|M.bovis_AF2122/97 PVNTQS---PYPGGGPIPEKYYRTLDPFVALAAAAATTQS--LVLGTGIA
Rv3079c|M.tuberculosis_H37Rv PVNTQS---PYPGGGPIPEKYYRTLDPFVALAAAAATTQS--LVLGTGIA
Mflv_4097|M.gilvum_PYR-GCK PAPTQR---WLEAGG------HDALDPFVAMGFAAAHTTT--LRLIPNIV
Mvan_2248|M.vanbaalenii_PYR-1 PAPTQR---WLEAGG------HDALDPFVAMGFAAAHTST--LRLIPNIV
MMAR_0393|M.marinum_M PAPSQR---WLEAGG------HDSLDPFVALGFAAAQTTS--LRLIPNIV
MUL_1043|M.ulcerans_Agy99 PAPSQR---WLEAGG------HDSLDPFVALGFAAAQTTS--LRLIPNIV
MSMEG_4820|M.smegmatis_MC2_155 PAPSQR---WLDAGG------HDAVDPFVAMAYAAAQTTT--LRLVPNIV
TH_2146|M.thermoresistible__bu PAPTQK---WLDHGG------HDTLDPFVAMGFAAAHTTT--LRLIPHIV
MAV_1888|M.avium_104 PFPDKD---WLAHGG------HHAFDPFVSLSFAAAATTR--LRLMTYIL
MAB_0366|M.abscessus_ATCC_1997 IGDTQSTYPYSPTGQSHLPDDIDIPDPLELLSFVAAATTT--LGLSTGVL
MLBr_00131|M.leprae_Br4923 SVATPK---YLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVT
. :* :. ** . * * :
Mb3106c|M.bovis_AF2122/97 LIPERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGR
Rv3079c|M.tuberculosis_H37Rv LIPERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGR
Mflv_4097|M.gilvum_PYR-GCK VLPYRNPFVVAKAGATLDLISDGRFTLAVGVGYLKREFAALGVEFDERAA
Mvan_2248|M.vanbaalenii_PYR-1 VLPYRNPFVVAKAGATLDLISEGRFTLAVGVGYLKREFTALGVDFDERAE
MMAR_0393|M.marinum_M VLPYRNPFVVAKSAATLDLLSGGRFILAVGVGYLKREFAALGVDHAERAE
MUL_1043|M.ulcerans_Agy99 VLPYRNPFVVAKSAATLDLLSGGRFILAVGVGYLKREFAALGVDHAERAE
MSMEG_4820|M.smegmatis_MC2_155 VLPYRNPFVVAKSGATLDLLSGGRFTLAVGVGYLKREFAALGVAFDERTE
TH_2146|M.thermoresistible__bu VLPYRNPFVVAKAGASVDLLSGGRFTLGVGVGYLKREFAALGVDFEERAA
MAV_1888|M.avium_104 VSGYRSPYLTAKAAASFDLLSGGRFTLGTGAGYLKPEFEALGADFHRRGA
MAB_0366|M.abscessus_ATCC_1997 VLPDHHPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRRGR
MLBr_00131|M.leprae_Br4923 DAGRRNPAVTAQAAATLHLLTRGKAMLGIGVG-EREGNEPYGVEWTKPVA
: * : *: *:.. :: *: : *.* : *
Mb3106c|M.bovis_AF2122/97 VIDERLRAIIEIWTQEQ--AEFHGTYVDFDPIYCWPKPVTKPYPPLYVGG
Rv3079c|M.tuberculosis_H37Rv VIDERLRAIIEIWTQEQ--AEFHGTYVDFDPIYCWPKPVTKPYPPLYVGG
Mflv_4097|M.gilvum_PYR-GCK VFEEALDVITQIWTTDD--LSYDGRNFSAKGITAHPKPLTTPHPPIWVGG
Mvan_2248|M.vanbaalenii_PYR-1 LFEESLQVIRDAWTTDD--ITFEGKHFSAKGITAHPRPVSTPHPPIWVGG
MMAR_0393|M.marinum_M LFEEALQVIRAVWTSDD--ISFEGRHFSARGITAHPRPASNPYPPIWVGG
MUL_1043|M.ulcerans_Agy99 LFDEALQVIRAVWTSDD--ISFEGRHFSARGITAHPRPASNPYPPIWVGG
MSMEG_4820|M.smegmatis_MC2_155 LFDESLEVIRGIWTTDD--FTYEGMHFSARGITAHPRPVNP--PPIWIGG
TH_2146|M.thermoresistible__bu LFEEALEVIRAIWTTDN--VSYTGRHFTADGITAHPHPVTKPHPPIWIGG
MAV_1888|M.avium_104 LLDEAIAAWKATWAGD----EHHGPEFGVAGHLALPLPVTAGGPPIWIGG
MAB_0366|M.abscessus_ATCC_1997 AADEAIAVMRALWSTDGP-TSHDGEFYSFRNAYSYPKPVRPQGVPLYIGG
MLBr_00131|M.leprae_Br4923 RFQEALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPEIWVAA
:* : . * : . * :::..
Mb3106c|M.bovis_AF2122/97 GP-ANFPRIARLNAGWIAISPSP--------------QRLSGPLQRLRAM
Rv3079c|M.tuberculosis_H37Rv GP-ANFPRIARLNAGWIAISPSP--------------QRLSGPLQRLRAM
Mflv_4097|M.gilvum_PYR-GCK NTSAARARVAKYAQGWCPFRAPAMLAQTARTAALETTEHLAKGIDDLRRR
Mvan_2248|M.vanbaalenii_PYR-1 NTSAARARVARYAQGWCPFRAPAVLAQTARTAALETVEHLKAGIDDLRRR
MMAR_0393|M.marinum_M NTAAARRRVAAHGDGWCPFPAPAPLAQTAGTAAIDSADRLAAGIDDLRRK
MUL_1043|M.ulcerans_Agy99 NTAAARRRVAVHGDGWCPFPAPAPLAQTAGTAAIDSADRLAAGIDDLRRK
MSMEG_4820|M.smegmatis_MC2_155 NTAAARARVARHGDGWCPFAAPPGLAQTAGTAAIDSIERLAAGIADLRAK
TH_2146|M.thermoresistible__bu NTGAARQRVADHGAGWCPFPAPAVLAQTARTAAMDSAEALAAGITDLHRR
MAV_1888|M.avium_104 NSKAARRRVVETANGWIPMGQSGEMATITRTPPLEDIARLASLISEVNKQ
MAB_0366|M.abscessus_ATCC_1997 HSKAAARRAGRLGSGFQPLGLVG--------------DDLTAAVGVMRAA
MLBr_00131|M.leprae_Br4923 HGPRMLQATGRYADAWIPIVLVRP-------------TDYSCALEVVRTA
.: .: : :.
Mb3106c|M.bovis_AF2122/97 AGG------DVPVTVC--QWG-----------EAAAKDLEGYRHLGVERV
Rv3079c|M.tuberculosis_H37Rv AGG------DVPVTVC--QWG-----------EAAAKDLEGYRHLGVERV
Mflv_4097|M.gilvum_PYR-GCK LEDAGRDPADVDITFT--NDAGGAPGTDDFNADEFLAGAEELERAGVTWL
Mvan_2248|M.vanbaalenii_PYR-1 LEGTGRDPFDIDITFT--NDAGGSPGAADFNADEFLSGAAELERAGVTWI
MMAR_0393|M.marinum_M CDAAGRDFSAIDVTFT--NFDGGGPASADFNADAYLGGLEKLATLGVTWV
MUL_1043|M.ulcerans_Agy99 CDAAGRDFSAIDVTFT--NFDGGGPASADFNADAYLGGLEKLAMLGVTWV
MSMEG_4820|M.smegmatis_MC2_155 LDAAQRDPSTVDIVFT--NFDGGNPGDDDFDADAYLAGVDQLAALGVTWL
TH_2146|M.thermoresistible__bu LEATGRDPADVDVVFS--NLTGGTPGRADFNADAYLDGVAKLGALGVTWL
MAV_1888|M.avium_104 RAERGRDAADVSFVPF--EADKLVSGDCGDFIESVKPRLAEYAEAGVTWI
MAB_0366|M.abscessus_ATCC_1997 AVDAGRDPRGLDLVLG--HGLHR--------VDQAALDQAAHAGAGRMLL
MLBr_00131|M.leprae_Br4923 ASDAGRDPMSITPAAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWA
: . : *
Mb3106c|M.bovis_AF2122/97 LLELPTEPRDPTLRYLDKLQAELARLA-----------------------
Rv3079c|M.tuberculosis_H37Rv LLELPTEPRDPTLRYLDKLQAELARLA-----------------------
Mflv_4097|M.gilvum_PYR-GCK QVNVPGDSLAHAVEAIEGFGETVIAQR-----------------------
Mvan_2248|M.vanbaalenii_PYR-1 QVTVPGDSLAHTLEAIEEFGGSVIGRP-----------------------
MMAR_0393|M.marinum_M HVGLPGDGLAHALECIDRFRVQVIEAA-----------------------
MUL_1043|M.ulcerans_Agy99 HVGLPGDGLAHALECIDRFRVQVIEAA-----------------------
MSMEG_4820|M.smegmatis_MC2_155 HVTIPGDSLAHALETIEGFGKSVIAR------------------------
TH_2146|M.thermoresistible__bu QVPIPGDSLNHALEAIEAFGSEVIGKL-----------------------
MAV_1888|M.avium_104 TVEPASRTFSDFRADVELMATELVEAPWVSRRLGLLDSDQGLVGPVCIVE
MAB_0366|M.abscessus_ATCC_1997 SASRRATTLEAVLEEMAGCATRLELGGPR---------------------
MLBr_00131|M.leprae_Br4923 RHGVEHPMGADFAGVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPE
:
Mb3106c|M.bovis_AF2122/97 --------------------------------------------------
Rv3079c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2248|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0393|M.marinum_M --------------------------------------------------
MUL_1043|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_4820|M.smegmatis_MC2_155 --------------------------------------------------
TH_2146|M.thermoresistible__bu --------------------------------------------------
MAV_1888|M.avium_104 RGFELRGWDVAEVAVQAAGVVPVDPTEGGEFYVLDGLPRSASSRPVDQLG
MAB_0366|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00131|M.leprae_Br4923 EVIDQVAEWRDHGLKYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL-
Mb3106c|M.bovis_AF2122/97 ---------------------
Rv3079c|M.tuberculosis_H37Rv ---------------------
Mflv_4097|M.gilvum_PYR-GCK ---------------------
Mvan_2248|M.vanbaalenii_PYR-1 ---------------------
MMAR_0393|M.marinum_M ---------------------
MUL_1043|M.ulcerans_Agy99 ---------------------
MSMEG_4820|M.smegmatis_MC2_155 ---------------------
TH_2146|M.thermoresistible__bu ---------------------
MAV_1888|M.avium_104 LVVTVDCLRESVIETISNGPN
MAB_0366|M.abscessus_ATCC_1997 ---------------------
MLBr_00131|M.leprae_Br4923 ---------------------