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ELKGTEVRYNLMFPMRAVKHWNRWCEGAGIGDVARLVEEAGFDGFSMSEHPYPDREWLARGGHHAFDPFV SLSFAAGATTRVRLMTYILVSGYRSPYLTAKAAASFDLLSGGRFTLGTGAGYLKAEFEALGADFDRRGAL LDEAIAAWKATWAGVDHAGPEFGVSGHVALPPPLTTGGPPIWIGGNGAAAQRRVVEVADGWMPMAASGEM AAITRARPLEDIDTLGDWIARVNKQRAEAGRGAADVAFVPFEAHLLASGNCERFCAAVQPRLDAYAEAGV TWITIEPASRSYTDFRTDIDMLSSQLINR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2605 | - | - | 100% (310) | hypothetical protein MAV_2605 |
| M. avium 104 | MAV_1888 | - | e-137 | 75.75% (301) | hypothetical protein MAV_1888 |
| M. avium 104 | MAV_5129 | - | 3e-55 | 39.58% (283) | hypothetical protein MAV_5129 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 1e-20 | 32.12% (193) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_4097 | - | 2e-54 | 40.70% (285) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 1e-20 | 32.12% (193) | hypothetical protein Rv3079c |
| M. leprae Br4923 | MLBr_00269 | - | 5e-10 | 28.33% (180) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 2e-25 | 33.89% (239) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_0393 | - | 9e-54 | 40.28% (283) | hypothetical protein MMAR_0393 |
| M. smegmatis MC2 155 | MSMEG_4820 | - | 6e-53 | 40.28% (283) | hypothetical protein MSMEG_4820 |
| M. thermoresistible (build 8) | TH_2146 | - | 3e-56 | 38.96% (308) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1043 | - | 7e-53 | 42.59% (263) | hypothetical protein MUL_1043 |
| M. vanbaalenii PYR-1 | Mvan_2248 | - | 1e-51 | 37.34% (308) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 ---------------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAE
Rv3079c|M.tuberculosis_H37Rv ---------------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAE
Mflv_4097|M.gilvum_PYR-GCK -------MQFAITHPMHSHPYNPELVTGAGIARVAVAAEKAGFGGFGFTD
Mvan_2248|M.vanbaalenii_PYR-1 -------MQFAITHPMHSHPYNPELVTGTGIAQVAQAAEKAGFGGFGFTD
TH_2146|M.thermoresistible__bu -------MRFAFTYPMDSHPYHPDLATGAAVARVAATAETAGFSGFGFTD
MMAR_0393|M.marinum_M -------MRFIITHPMHSHPYHPELASGAGVAAVAAAAERAGFHGFGFTD
MUL_1043|M.ulcerans_Agy99 ---------------MHSHPYHPELASGAGVAAVAAAAERAGFHGFGFTD
MSMEG_4820|M.smegmatis_MC2_155 -------MRYSITHPMHSHPYHPDLVSGSGVVAVAAAAEAAGFDGFGFTD
MAV_2605|M.avium_104 MELKGTEVRYNLMFPMRAVKHWNRWCEGAGIGDVARLVEEAGFDGFSMSE
MAB_0366|M.abscessus_ATCC_1997 -----------MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVE
MLBr_00269|M.leprae_Br4923 -----------MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSD
.. * *: . :
Mb3106c|M.bovis_AF2122/97 HTHIPVNTQ---SPYPGGGPIPEKYYRTLDPFVALAAAAATTQSLVLGTG
Rv3079c|M.tuberculosis_H37Rv HTHIPVNTQ---SPYPGGGPIPEKYYRTLDPFVALAAAAATTQSLVLGTG
Mflv_4097|M.gilvum_PYR-GCK H---PAPTQ---RWLEAGG------HDALDPFVAMGFAAAHTTTLRLIPN
Mvan_2248|M.vanbaalenii_PYR-1 H---PAPTQ---RWLEAGG------HDALDPFVAMGFAAAHTSTLRLIPN
TH_2146|M.thermoresistible__bu H---PAPTQ---KWLDHGG------HDTLDPFVAMGFAAAHTTTLRLIPH
MMAR_0393|M.marinum_M H---PAPSQ---RWLEAGG------HDSLDPFVALGFAAAQTTSLRLIPN
MUL_1043|M.ulcerans_Agy99 H---PAPSQ---RWLEAGG------HDSLDPFVALGFAAAQTTSLRLIPN
MSMEG_4820|M.smegmatis_MC2_155 H---PAPSQ---RWLDAGG------HDAVDPFVAMAYAAAQTTTLRLVPN
MAV_2605|M.avium_104 H---PYPDR---EWLARGG------HHAFDPFVSLSFAAGATTRVRLMTY
MAB_0366|M.abscessus_ATCC_1997 HAVVIGDTQSTYPYSPTGQSHLPDDIDIPDPLELLSFVAAATTTLGLSTG
MLBr_00269|M.leprae_Br4923 HFQ---------PWRHQGG-------HASFSLSWMTAVGERTNRILLGTS
* * .: : .. * : * .
Mb3106c|M.bovis_AF2122/97 IALIPERD-PIVTAKEVASLDLVSQGRFRFGVGVGWLREEVAN----HGV
Rv3079c|M.tuberculosis_H37Rv IALIPERD-PIVTAKEVASLDLVSQGRFRFGVGVGWLREEVAN----HGV
Mflv_4097|M.gilvum_PYR-GCK IVVLPYRN-PFVVAKAGATLDLISDGRFTLAVGVGYLKREFAA----LGV
Mvan_2248|M.vanbaalenii_PYR-1 IVVLPYRN-PFVVAKAGATLDLISEGRFTLAVGVGYLKREFTA----LGV
TH_2146|M.thermoresistible__bu IVVLPYRN-PFVVAKAGASVDLLSGGRFTLGVGVGYLKREFAA----LGV
MMAR_0393|M.marinum_M IVVLPYRN-PFVVAKSAATLDLLSGGRFILAVGVGYLKREFAA----LGV
MUL_1043|M.ulcerans_Agy99 IVVLPYRN-PFVVAKSAATLDLLSGGRFILAVGVGYLKREFAA----LGV
MSMEG_4820|M.smegmatis_MC2_155 IVVLPYRN-PFVVAKSGATLDLLSGGRFTLAVGVGYLKREFAA----LGV
MAV_2605|M.avium_104 ILVSGYRS-PYLTAKAAASFDLLSGGRFTLGTGAGYLKAEFEA----LGA
MAB_0366|M.abscessus_ATCC_1997 VLVLPDHH-PVVLAKRLATLDRLSRGRLRICAGVGWMREEIEA----CGG
MLBr_00269|M.leprae_Br4923 VLTPTFRYNPAVIGQAFATMGCLYPNRVFLGVGTGEALNEVATGYQGAWP
: : * : .: *:.. : .*. : .*.* *.
Mb3106c|M.bovis_AF2122/97 DPAVRGRVIDERLRAIIEIWTQE-QAEFHGTYVDFDPIYCWPKPVTKPYP
Rv3079c|M.tuberculosis_H37Rv DPAVRGRVIDERLRAIIEIWTQE-QAEFHGTYVDFDPIYCWPKPVTKPYP
Mflv_4097|M.gilvum_PYR-GCK EFDERAAVFEEALDVITQIWTTD-DLSYDGRNFSAKGITAHPKPLTTPHP
Mvan_2248|M.vanbaalenii_PYR-1 DFDERAELFEESLQVIRDAWTTD-DITFEGKHFSAKGITAHPRPVSTPHP
TH_2146|M.thermoresistible__bu DFEERAALFEEALEVIRAIWTTD-NVSYTGRHFTADGITAHPHPVTKPHP
MMAR_0393|M.marinum_M DHAERAELFEEALQVIRAVWTSD-DISFEGRHFSARGITAHPRPASNPYP
MUL_1043|M.ulcerans_Agy99 DHAERAELFDEALQVIRAVWTSD-DISFEGRHFSARGITAHPRPASNPYP
MSMEG_4820|M.smegmatis_MC2_155 AFDERTELFDESLEVIRGIWTTD-DFTYEGMHFSARGITAHPRPVNP--P
MAV_2605|M.avium_104 DFDRRGALLDEAIAAWKATWAG---VDHAGPEFGVSGHVALPPPLTTGGP
MAB_0366|M.abscessus_ATCC_1997 DFDRRGRAADEAIAVMRALWSTDGPTSHDGEFYSFRNAYSYPKPVRPQGV
MLBr_00269|M.leprae_Br4923 EFKERFARLRESVRLMRELWRGD-RVDFDGDYYQLKGASIY--DVPEGGV
* * : * . *
Mb3106c|M.bovis_AF2122/97 PLYVGG-GPANFPRIARLNAGWIAISP--------------SPQRLSGP-
Rv3079c|M.tuberculosis_H37Rv PLYVGG-GPANFPRIARLNAGWIAISP--------------SPQRLSGP-
Mflv_4097|M.gilvum_PYR-GCK PIWVGGNTSAARARVAKYAQGWCPFRAPAMLAQTARTAALETTEHLAKG-
Mvan_2248|M.vanbaalenii_PYR-1 PIWVGGNTSAARARVARYAQGWCPFRAPAVLAQTARTAALETVEHLKAG-
TH_2146|M.thermoresistible__bu PIWIGGNTGAARQRVADHGAGWCPFPAPAVLAQTARTAAMDSAEALAAG-
MMAR_0393|M.marinum_M PIWVGGNTAAARRRVAAHGDGWCPFPAPAPLAQTAGTAAIDSADRLAAG-
MUL_1043|M.ulcerans_Agy99 PIWVGGNTAAARRRVAVHGDGWCPFPAPAPLAQTAGTAAIDSADRLAAG-
MSMEG_4820|M.smegmatis_MC2_155 PIWIGGNTAAARARVARHGDGWCPFAAPPGLAQTAGTAAIDSIERLAAG-
MAV_2605|M.avium_104 PIWIGGNGAAAQRRVVEVADGWMPMAASGEMAAITRARPLEDIDTLGDW-
MAB_0366|M.abscessus_ATCC_1997 PLYIGGHSKAAARRAGRLGSGFQPLGLVG--------------DDLTAA-
MLBr_00269|M.leprae_Br4923 PIYIAAGGPEVAKYAGRAGEGFVCTSGKGEELYTEKLIPAVLEGAAVAGR
*:::.. *:
Mb3106c|M.bovis_AF2122/97 ---------------------------------LQRLR------------
Rv3079c|M.tuberculosis_H37Rv ---------------------------------LQRLR------------
Mflv_4097|M.gilvum_PYR-GCK ---------------------------------IDDLRRRLEDAGRDPAD
Mvan_2248|M.vanbaalenii_PYR-1 ---------------------------------IDDLRRRLEGTGRDPFD
TH_2146|M.thermoresistible__bu ---------------------------------ITDLHRRLEATGRDPAD
MMAR_0393|M.marinum_M ---------------------------------IDDLRRKCDAAGRDFSA
MUL_1043|M.ulcerans_Agy99 ---------------------------------IDDLRRKCDAAGRDFSA
MSMEG_4820|M.smegmatis_MC2_155 ---------------------------------IADLRAKLDAAQRDPST
MAV_2605|M.avium_104 ---------------------------------IARVNKQRAEAGRGAAD
MAB_0366|M.abscessus_ATCC_1997 ---------------------------------VGVMRAAAVDAGRDP--
MLBr_00269|M.leprae_Br4923 DADDIDKMIEIKMSYDPDPEQALSNIRFWAPLSLAAEQKHSIDDPIEMEK
: .
Mb3106c|M.bovis_AF2122/97 -----AMAGGDVPVTVCQWGEAAAKDLEGYRHLGVERVLLELPTEPRDPT
Rv3079c|M.tuberculosis_H37Rv -----AMAGGDVPVTVCQWGEAAAKDLEGYRHLGVERVLLELPTEPRDPT
Mflv_4097|M.gilvum_PYR-GCK VDITFTNDAGGAPGTDDFNADEFLAGAEELERAGVTWLQVNVPGDSLAHA
Mvan_2248|M.vanbaalenii_PYR-1 IDITFTNDAGGSPGAADFNADEFLSGAAELERAGVTWIQVTVPGDSLAHT
TH_2146|M.thermoresistible__bu VDVVFSNLTGGTPGRADFNADAYLDGVAKLGALGVTWLQVPIPGDSLNHA
MMAR_0393|M.marinum_M IDVTFTNFDGGGPASADFNADAYLGGLEKLATLGVTWVHVGLPGDGLAHA
MUL_1043|M.ulcerans_Agy99 IDVTFTNFDGGGPASADFNADAYLGGLEKLAMLGVTWVHVGLPGDGLAHA
MSMEG_4820|M.smegmatis_MC2_155 VDIVFTNFDGGNPGDDDFDADAYLAGVDQLAALGVTWLHVTIPGDSLAHA
MAV_2605|M.avium_104 VAFVPFEAHLLASGNCERFCAAVQPRLDAYAEAGVTWITIEPASRSYTDF
MAB_0366|M.abscessus_ATCC_1997 ------RGLDLVLGHGLHRVDQAALDQAAHAGAGRMLLSASRRATTLEAV
MLBr_00269|M.leprae_Br4923 VADALPIEQVAKRWIVVSDPDEAVARVGQYVTWGLNHLVFHAPGHNQRRF
* :
Mb3106c|M.bovis_AF2122/97 LRYLDKLQAELARLA--
Rv3079c|M.tuberculosis_H37Rv LRYLDKLQAELARLA--
Mflv_4097|M.gilvum_PYR-GCK VEAIEGFGETVIAQR--
Mvan_2248|M.vanbaalenii_PYR-1 LEAIEEFGGSVIGRP--
TH_2146|M.thermoresistible__bu LEAIEAFGSEVIGKL--
MMAR_0393|M.marinum_M LECIDRFRVQVIEAA--
MUL_1043|M.ulcerans_Agy99 LECIDRFRVQVIEAA--
MSMEG_4820|M.smegmatis_MC2_155 LETIEGFGKSVIAR---
MAV_2605|M.avium_104 RTDIDMLSSQLINR---
MAB_0366|M.abscessus_ATCC_1997 LEEMAGCATRLELGGPR
MLBr_00269|M.leprae_Br4923 LELFEKDLAPRLRRLG-
: