For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MASPAASTPQAALTIPADDITMAADAFGDPADPPVVLLHGGGQTRHSWKATAADLGGLGWYALTVDLRGH GDSGWSADGRYGLDRFASDVVRVTEFLARPPVLVGASLGGNASLAALGSRPDLALGLVLVDVSPFLQPSG TNRIRDFMVSHAEEGFGTLEEVADAVAAYLPHRPRPRNLDGLRKNLRLRDGRWYWHWDPAFMASPTDLPV QRDQLVDPARLGAAASSLRLPTLLVRGGESDVLSVDDAVRFLELVPHAEFASVAGAHHMVAGDDNAVFED VLGDFLARRVRSRLNLLNHR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1846 | - | - | 100% (300) | hydrolase, alpha/beta fold family protein |
| M. avium 104 | MAV_0677 | - | 2e-70 | 49.82% (275) | hydrolase, alpha/beta fold family protein |
| M. avium 104 | MAV_1254 | - | 1e-65 | 47.29% (277) | hydrolase, alpha/beta fold family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3502c | bpoA | 9e-65 | 48.67% (263) | peroxidase BpoA |
| M. gilvum PYR-GCK | Mflv_2096 | - | 2e-68 | 48.04% (281) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv3473c | bpoA | 1e-64 | 48.67% (263) | peroxidase BpoA |
| M. leprae Br4923 | MLBr_02297 | - | 1e-07 | 27.69% (260) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_2045 | - | 3e-60 | 44.93% (296) | putative hydrolase (alpha/beta fold) |
| M. marinum M | MMAR_4960 | bpoA | 3e-70 | 47.75% (289) | peroxidase BpoA |
| M. smegmatis MC2 155 | MSMEG_5209 | - | 4e-70 | 48.97% (292) | hydrolase, alpha/beta fold family protein |
| M. thermoresistible (build 8) | TH_0490 | bpoA | 7e-68 | 76.25% (160) | POSSIBLE PEROXIDASE BPOA (NON-HAEM PEROXIDASE) |
| M. ulcerans Agy99 | MUL_0147 | bpoB | 6e-67 | 46.23% (292) | peroxidase BpoB |
| M. vanbaalenii PYR-1 | Mvan_1862 | - | 1e-68 | 48.08% (287) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1846|M.avium_104 -----MASPAAS---TPQAALTIPADDITMAADAFGDPAD----------
TH_0490|M.thermoresistible__bu -----MSNDATN---AQRETLKIPSGDVTMVADAYGDPAD----------
Mb3502c|M.bovis_AF2122/97 --------------------------------------------------
Rv3473c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4960|M.marinum_M ---------MAT---APERFSVQGPDGVRIVADRCGDPRG----------
Mvan_1862|M.vanbaalenii_PYR-1 MRVSTYHPEMTS---APEQFLTDGHGGVRIVADRLGDPRA----------
Mflv_2096|M.gilvum_PYR-GCK -----MSIEHR----EPKTVTFRGADGLALVADEWNNPAQTEAFDR----
MSMEG_5209|M.smegmatis_MC2_155 -----MSTAQT----ESQTVAFRGVDDLTLVGDEWNKGAERAAD------
MUL_0147|M.ulcerans_Agy99 -----MSAMSN----NPRTVEFSGTEGITLVADEWNR--DTAAS------
MAB_2045|M.abscessus_ATCC_1997 -----MSAKRTGDSSAPVVERVPTADGLALAVDLYHCDAP----------
MLBr_02297|M.leprae_Br4923 ---MAMSNPSVTRIAGPWHHLDVHANGIRFHVVEAVPTQPAGQDCAPSAT
MAV_1846|M.avium_104 --PPVVLLHGGGQTRHSWKATAADLGGLGWYALTVDLRGHGDSGWSADGR
TH_0490|M.thermoresistible__bu --PPVVLLHGGGQTRHSWGSTAADLGAKDWYAVTVDLRGHGESGWSPDG-
Mb3502c|M.bovis_AF2122/97 ----MVFLHGGGQTRRSWGRAAAAVAERGWQAVTIDLRGHGESDWSSEGD
Rv3473c|M.tuberculosis_H37Rv ----MVFLHGGGQTRRSWGRAAAAVAERGWQAVTIDLRGHGESDWSSEGD
MMAR_4960|M.marinum_M --RAVVFLHGGGQTRRSWGRVAAVVAERGWQSVTVDLRGHGESDWSPHGD
Mvan_1862|M.vanbaalenii_PYR-1 --RAVVFLHGGGQTRRSWGRAAAAVAHRGWQAVTVDMRGHGESDWSPDGD
Mflv_2096|M.gilvum_PYR-GCK SRPSVLMMHGGGQNRFSWKKTGQILGEQGLHVVALDSRGHGDSDRSPDAR
MSMEG_5209|M.smegmatis_MC2_155 -RPTVLLLHGGGQNRYSWKNTGQILADQGFHVIALDARGHGDSDRSPSAN
MUL_0147|M.ulcerans_Agy99 GRPTILMLHGGCQNRFSWKNTGQILADTGLHVIALDTRGHGDSDRAPDAD
MAB_2045|M.abscessus_ATCC_1997 -RAVVLLLHGGGQSRHAWDVTAQRLHQRGYTVAAYDTRGHGDSDWDPDGR
MLBr_02297|M.leprae_Br4923 ARPLVMLLHGFGSFWWSWRHQLRGLTEA--RLVAVDLRGYGGSDKPPRG-
::::** . :* : : * **:* *. . .
MAV_1846|M.avium_104 YGLDRFASDVVRV--TEFLARPPVLVGASLGGNASLAALG-SRPDLALGL
TH_0490|M.thermoresistible__bu YGLDRFAGDVTCV--ADFLGRPPVYVGASLGGNASLAAIG-LRPDRALGL
Mb3502c|M.bovis_AF2122/97 YRLVSFAGDIQEV--LRNLPGQPALVGASLGGFAAMLLAGELSPGIASAV
Rv3473c|M.tuberculosis_H37Rv YRLVSFAGDIQEV--LRNLPGQPALVGASLGGFAAMLLAGELSPGIASAV
MMAR_4960|M.marinum_M YRVVSFAADIQEV--LRGLPPQPVLVGASLGGFTSMLLAGELSPGIASAV
Mvan_1862|M.vanbaalenii_PYR-1 YRVSSFAADVREI--LDRLPPRPVLVGASLGGITSMLLAGELARGIAAAV
Mflv_2096|M.gilvum_PYR-GCK YTVEALCEDTLRV--LEQIGRPTVLIGASMGGLTGILAARRAGPEVVTRL
MSMEG_5209|M.smegmatis_MC2_155 YSVDAMCGDVLAV--LYQISRPVALIGASMGGLTGLLAAHEAGPERVTQL
MUL_0147|M.ulcerans_Agy99 YAIETLTSDIRHV--LDAIGRPVVLIGASMGGLTGILVADSAGPDRVTGL
MAB_2045|M.abscessus_ATCC_1997 YDMDRLGSDLLAVRSYADSGRPVAAIGASLGGLTILGTHLLAPPDLWQAV
MLBr_02297|M.leprae_Br4923 YDGWTLAGDTAGL--IRALGHSSATLVGHAEGGLACWATALLHPRLVRAI
* : * : . : . * :
MAV_1846|M.avium_104 VLVDVSPFLQPSGTNRIRDFMVSHAEEGFGTLEEVADAVAAYLPHRPRPR
TH_0490|M.thermoresistible__bu VLVDVSPFLQPAGTSRIRDFMVSHAETGFGTLE-----------------
Mb3502c|M.bovis_AF2122/97 VLVDIVPNMDLAGASRIHAFMAERVESGFGSLDEVADVIANYNPHRPRPS
Rv3473c|M.tuberculosis_H37Rv VLVDIVPNMDLAGASRIHAFMAERVESGFGSLDEVADVIANYNPHRPRPS
MMAR_4960|M.marinum_M VLVDIVPNMDPSGASRIHAFMVERVESGFGSLDEVADMIAAYNPHRPRPT
Mvan_1862|M.vanbaalenii_PYR-1 VLVDIVPDMDPSGAERIHAFMADRMVDGFGSLDEVADMIAEFNPHRPRPA
Mflv_2096|M.gilvum_PYR-GCK VLVDVVPRYEKGGSARIRDFMFSHVH-GFDSLEQAADAVAEYLPHRAKPR
MSMEG_5209|M.smegmatis_MC2_155 VLVDVVPNFEKSGSARIRDFMASNVD-GFDTLEEAADAVAAYLPHRRRPR
MUL_0147|M.ulcerans_Agy99 VLVDVVPKYEKDGSARIRDFMFTNLH-GFATLEEAADAVATYLPHRTKPR
MAB_2045|M.abscessus_ATCC_1997 VLVDVTPRMEMDGARRVVAFMSAHPE-GFDSLESAADVIAAYNPHRPRPE
MLBr_02297|M.leprae_Br4923 ALINSP------HPAALRRSMLTHRNQGYALLPTLLRYQLPIWPERLLTR
.*:: . : * . *: *
MAV_1846|M.avium_104 N-LDGLRKNLRLR-DGRWYWHWDPAFMAS----PTDLPVQRDQLVDPARL
TH_0490|M.thermoresistible__bu --------------------------------------------------
Mb3502c|M.bovis_AF2122/97 D-PDGLVANLRRR-GDRWYWHWDPQFIGG----IAAFP--PVEVTDVDRM
Rv3473c|M.tuberculosis_H37Rv D-PDGLVANLRRR-GDRWYWHWDPQFIGG----IAAFP--PVEVTDVDRM
MMAR_4960|M.marinum_M D-LEGLTTNLRRR-GDRWYWHWDPRFISG----TAAFP--PIEVTEPHRL
Mvan_1862|M.vanbaalenii_PYR-1 D-LDGLRNNLRRR-GERWYWHWDPQFIDG----SAANP--PIEVTDTERL
Mflv_2096|M.gilvum_PYR-GCK S-PEGLKKNLRRR-NGRWYWHWDPAFLTK----PSEDPFARVEQLEQA--
MSMEG_5209|M.smegmatis_MC2_155 N-PEGLKKNLRLR-DGRWYWHWDPAFLGK----PHDDPFVRVERLEQA--
MUL_0147|M.ulcerans_Agy99 S-PEGLKKNLRLR-DGRWYWHWDPAMMTA----PGDDPELRTENFERA--
MAB_2045|M.abscessus_ATCC_1997 N-LDGLRKVLARREDGRWSWRWDPAFVTSNFQFLQGDPDEGAEYFEMMSA
MLBr_02297|M.leprae_Br4923 NNAAEIERLVRSRSSAKWQACEDFAVTIDHLRIAIQIPAAAHCALEYQRW
MAV_1846|M.avium_104 GA-----------AASSLR---LPTLLVRGGESDVLSVDDAVRFLELVPH
TH_0490|M.thermoresistible__bu --------------------------------------------------
Mb3502c|M.bovis_AF2122/97 NA-----------AVATILRDEVPVLLVRGQVSDIVRQESADQFLSRFPQ
Rv3473c|M.tuberculosis_H37Rv NA-----------AVATILRDEVPVLLVRGQVSDIVRQESADQFLSRFPQ
MMAR_4960|M.marinum_M YA-----------AVDTILRGGVPMLLIRGQMSDLVSQERAEEFLARFPN
Mvan_1862|M.vanbaalenii_PYR-1 HS-----------AVEAILADGVPVLLVRGQVSDLVSRERADAFVARFPQ
Mflv_2096|M.gilvum_PYR-GCK -----------------ATELTVPILLIRGKLSDVVSEEAVQDFLAKVPG
MSMEG_5209|M.smegmatis_MC2_155 -----------------AVNLTVPILLIRGKLSDVVSPEGVAEFLEKVPA
MUL_0147|M.ulcerans_Agy99 -----------------AMNLTIPILLIRGKLSDVVTSEGVQDFLDKVPH
MAB_2045|M.abscessus_ATCC_1997 -F-----------LLDGARQVSAPTLLVRGLLSDIVSEETVRHFLTVVPH
MLBr_02297|M.leprae_Br4923 AVRSQLRNEGRKFMKSMSRPFSVPLLHVRGDADPYLLADSVDRTRRYAPH
MAV_1846|M.avium_104 AEFASVAGAHHMVAGDDNAVFEDVLGDFLARRVRSRLNLLNHR
TH_0490|M.thermoresistible__bu -------------------------------------------
Mb3502c|M.bovis_AF2122/97 VEFTDVRGAGHMVAGDRNDAFAGAVLDFLARHVGVR-------
Rv3473c|M.tuberculosis_H37Rv VEFTDVRGAGHMVAGDRNDAFAGAVLDFLARHVGVR-------
MMAR_4960|M.marinum_M VEFTDVRGAGHMVAGDRNDIFAAAVLDFLSRHLDAG-------
Mvan_1862|M.vanbaalenii_PYR-1 IAFVDVEGAGHMVAGDRNDLFADAVLDFLARSEIARP------
Mflv_2096|M.gilvum_PYR-GCK AEFAELSGAGHTAAGDDNDAFSEVVTRFVLR------------
MSMEG_5209|M.smegmatis_MC2_155 AEFVELSDAGHTAAGDDNDAFTQVVVEFVNR------------
MUL_0147|M.ulcerans_Agy99 AEFVELSNAGHTAAGDDNDAFTEVVVDFVKRRAATG-------
MAB_2045|M.abscessus_ATCC_1997 AQTVDVSGAGHMIAGDNNDAFSTAVVEFLDRTI----------
MLBr_02297|M.leprae_Br4923 GRYVSVSDAGHFSHEEAPEEINRYLTRFLKQVHGPRLS-----