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TSHPANPEPGARRRGDKQRQAILAAVRELLQEKPFAELSVSTISLRAGVARSGFYFYFDSKYAVLAQLMA EATEELEQLTQYFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTACNEARHTDVEIRNLMDQQFEVVLA QIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALMLTGDPVLTGPDSDRDRRVAVLEQLWLHALWAGRP *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3926 | - | - | 100% (211) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5064 | - | 2e-14 | 25.81% (186) | transcriptional regulator, TetR family protein, putative |
| M. avium 104 | MAV_0173 | - | 7e-14 | 26.77% (198) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3084c | - | 2e-83 | 69.81% (212) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4314 | - | 3e-61 | 59.05% (210) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3058c | - | 2e-83 | 69.81% (212) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 2e-14 | 28.04% (214) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3422c | - | 3e-56 | 56.99% (193) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1635 | - | 1e-89 | 79.00% (200) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2290 | - | 8e-66 | 62.81% (199) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1635 | - | 4e-63 | 59.13% (208) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3401 | - | 7e-90 | 79.00% (200) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2032 | - | 2e-63 | 59.81% (209) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3084c|M.bovis_AF2122/97 -------MTSHAADEKQ-------AAPPMRRRGDRHRQAILRAARELLEE
Rv3058c|M.tuberculosis_H37Rv -------MTSHAADEKQ-------AAPPMRRRGDRHRQAILRAARELLEE
MMAR_1635|M.marinum_M ------MVNGQAADEKQ-------RGPTLRRRGDKQRQAILQAVRELLEE
MUL_3401|M.ulcerans_Agy99 ------MVNGQAADEKQ-------RGPTLRRRGDKQRQAILQAVRELLEE
MAV_3926|M.avium_104 -------MTSHPANPE----------PGARRRGDKQRQAILAAVRELLQE
MSMEG_2290|M.smegmatis_MC2_155 -------MTAESVPQGSNGSAGATAAQARRSRGDRQREAIVAAVRELLEE
TH_1635|M.thermoresistible__bu -------VTTDSP-----------AREDRRSRGDRQRDAIVAAVRELLEE
Mflv_4314|M.gilvum_PYR-GCK -MPRSNSMTAEPAP-----------TDLRRSRGDRQRDAIVTAVRELLHE
Mvan_2032|M.vanbaalenii_PYR-1 -------MTAEPAP-----------SDLRRSRGDRQRDAIIAAVRELLQE
MAB_3422c|M.abscessus_ATCC_199 -------MVSPARS-------------GTQTRGDRQRDAIMTAVAELIAE
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASR-------GRRSSQLSGDDREQAILAVAERLLAE
: ** :.:**: .. .*: *
Mb3084c|M.bovis_AF2122/97 -TPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQ
Rv3058c|M.tuberculosis_H37Rv -TPFAELSVRAISLRAGVARSGFYFYFDSKYSVLAQILAEATEELEEASQ
MMAR_1635|M.marinum_M -RPFAELSVATISNRAGVARSGFYFYFDSKYSVLAQLMAEAVEELEERTQ
MUL_3401|M.ulcerans_Agy99 -RPFAELSVATISNRAGVARSGFYFYFDSKYSVLAQLMAEAVEELEERTQ
MAV_3926|M.avium_104 -KPFAELSVSTISLRAGVARSGFYFYFDSKYAVLAQLMAEATEELEQLTQ
MSMEG_2290|M.smegmatis_MC2_155 -QPFADISVSTISERAGVARSGFYFYFDSKYAVLAVILAEAMEELDALTH
TH_1635|M.thermoresistible__bu -RSFADLSVSTISERAGVARSGFYFYFDSKYAVLAVILGEAMEELDKLTQ
Mflv_4314|M.gilvum_PYR-GCK -RPFAELSVSTISERAGVARSGFYFYFDSKYAVLAVIIAEAMAELDQLTH
Mvan_2032|M.vanbaalenii_PYR-1 -RAFADLSVSTISERAGVARSGFYFYFDSKYAVLAVIVAEAMAELDQLTH
MAB_3422c|M.abscessus_ATCC_199 NHSFADLSVSAISERAGVGRSGFYFYFDSKYSVLAQMVGDAFAELDELTH
MLBr_01070|M.leprae_Br4923 -RPLGDFSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVE
.:.::** :: **:.*. ***** ** :** :: : : .
Mb3084c|M.bovis_AF2122/97 HFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL
Rv3058c|M.tuberculosis_H37Rv HFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRACNAARQSDMEIRDIL
MMAR_1635|M.marinum_M YFAPRQPGESPQEFAKRMVGSAAIVYTHNDPVMMACNAARHTDIEIRDIL
MUL_3401|M.ulcerans_Agy99 YFAPRQPGESPQEFAKRMVGSAAIVYTHNDPVMMACNAARHTDIEIRDIL
MAV_3926|M.avium_104 YFAPRQPGESPEQFAKRMVGSAAAVYAHNDPVMTACNEARHTDVEIRNLM
MSMEG_2290|M.smegmatis_MC2_155 NFAPRGENESPAAFAKRMVGSAAAVYATNDPVMSACTVAQNTDAQIRDIM
TH_1635|M.thermoresistible__bu NFAPRGAEETPAEFARRMVGSAAAVYASNDPVMRACSAAQNTDAQIREMM
Mflv_4314|M.gilvum_PYR-GCK SFGPRDEAESPSEFAKRMVGYAAIVFASNDPIMRACNLARSTDAQIREIM
Mvan_2032|M.vanbaalenii_PYR-1 DFAPREPGESPSDFAKRMVGYAATVYARNDPIMGACNLARNTDAEIREIM
MAB_3422c|M.abscessus_ATCC_199 YFAPRGEEETPEQFAHRMVGSAAASFAHNDPLMKACQEARITDPTIAGLL
MLBr_01070|M.leprae_Br4923 ALAEQLPAD-PAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLW
:. : : * . . : : .: * *: :. : :
Mb3084c|M.bovis_AF2122/97 ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDA
Rv3058c|M.tuberculosis_H37Rv ERQFQVLLRETIGVFEAEVKAGTAHPISEDLPTLVRTLAATTALMLTGDA
MMAR_1635|M.marinum_M DQQFDVVLREIVGVIDAEMRAGTANPISEDLPTLIRTLTATTALMLTGDA
MUL_3401|M.ulcerans_Agy99 DQQFDVVLREIVGVIDAEMRAGTANPISEDLPTLIRTLTATTALMLTGDA
MAV_3926|M.avium_104 DQQFEVVLAQIVGIVEAEMKAGTARPISDDLPTLIRTLAGTTALMLTGDP
MSMEG_2290|M.smegmatis_MC2_155 NDFEDATIAKIVGVIE---QDTGARPISDDLPALVRTLTATTAMTLSRDA
TH_1635|M.thermoresistible__bu GDLQAIVIDKIVGVIE---QDASAQPITDDLHALVRTLVATTALTLTHDS
Mflv_4314|M.gilvum_PYR-GCK DDFQNTVVEKIVGLVG---RDAGARPISDDLPALVRVMIAVTSSTLAHDS
Mvan_2032|M.vanbaalenii_PYR-1 DDFQDSVIDKIVDLVG---RDSGARPVSQDLPALVRTLIAMTSMTLAHDS
MAB_3422c|M.abscessus_ATCC_199 DDLTDVVIEKILKIAETEVKERGAQPISDDLPALVRSLVALTASTVSGDS
MLBr_01070|M.leprae_Br4923 STVMQQWIDYNTAAIQAE-RKCGVAPDTIPAEDLAVALQLMTERVMAATF
: : . * : * : * ::
Mb3084c|M.bovis_AF2122/97 LLVGPDSDAARRVRVLEQMWLNALWGGGKAP----
Rv3058c|M.tuberculosis_H37Rv LLVGPDSDAARRVRVLEQMWLNALWGGGKAP----
MMAR_1635|M.marinum_M LLVGRDSDLERRVRVLEQMWLNALWGGPIRT----
MUL_3401|M.ulcerans_Agy99 LLVGRDSDLERRVRVLEQMWLNALWGGPIRT----
MAV_3926|M.avium_104 VLTGPDSDRDRRVAVLEQLWLHALWAG--RP----
MSMEG_2290|M.smegmatis_MC2_155 GFVGRDADPARAVEIVERLWLSALWGG--LPE---
TH_1635|M.thermoresistible__bu AFVGRATDISRAVDVVERLWLYSLWGGGNLPER--
Mflv_4314|M.gilvum_PYR-GCK AFVGRDGDPARALAVVERLWESSLWGGQ-------
Mvan_2032|M.vanbaalenii_PYR-1 AFVGRGADPARAVEIVERLWLSSLWGGDSLETHKA
MAB_3422c|M.abscessus_ATCC_199 SFVGRNTDPARAIATVETLWRVSLLGR--------
MLBr_01070|M.leprae_Br4923 SDEKPLIPDKKVIDTLVHIWLASIYGS--------
: : : :* :: .