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MIAVTHVGPDRYSIGGTQSVIRVIHDNNIGADRIRVLSTWNGPNQVKNLWLTARAGTTLARSAAGSIVHF HVSNGGAWLREGPLIRLAGAKGFRVIVTLHGSDFPEFARSRPRFVAATLRHADKVILLSEQARAALLEVA PTVRTAVVPNPIVVDEEAPGAGSTPPVVLFAGTVGRRKGVDRLVAAWKLLLAEGIEGRCRIIGPIDDYIP PATERLTVEGPIPPDRVRALLRSVRVVALPSFAEGMPMILTEALAGARPFVATPVGGTAQIAPDPGMLVP VDDVPALADAIGRYLRDPELAQRDGLRGQQHIAATRSPRVIDAELRRIYQGCDVAAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1137 | - | - | 100% (337) | glycosyl transferase, group 1 family protein |
| M. avium 104 | MAV_1357 | - | 3e-12 | 27.87% (244) | glycogen synthase |
| M. avium 104 | MAV_4082 | - | 2e-11 | 31.05% (248) | transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1244c | - | 2e-08 | 25.41% (244) | putative glycosyl transferase |
| M. gilvum PYR-GCK | Mflv_2191 | - | 5e-12 | 27.87% (244) | glycogen synthase |
| M. tuberculosis H37Rv | Rv1212c | - | 2e-08 | 25.41% (244) | putative glycosyl transferase |
| M. leprae Br4923 | MLBr_01715 | - | 9e-08 | 21.82% (307) | putative transferase |
| M. abscessus ATCC 19977 | MAB_1019c | - | 1e-10 | 26.91% (301) | glycosyl transferase |
| M. marinum M | MMAR_4514 | - | 3e-12 | 29.21% (267) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_5951 | - | 2e-15 | 29.27% (287) | glycosyl transferase, group 1, putative |
| M. thermoresistible (build 8) | TH_0550 | - | 2e-11 | 27.87% (244) | glycogen synthase |
| M. ulcerans Agy99 | MUL_1919 | - | 4e-09 | 23.95% (309) | transferase |
| M. vanbaalenii PYR-1 | Mvan_4504 | - | 5e-13 | 28.69% (244) | glycogen synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01715|M.leprae_Br4923 MFIQRHAVVRGIFGTFAPAEGTTLMKILIVSWEYPPVVIGGLGRHVHHLS
MUL_1919|M.ulcerans_Agy99 ------------------------MKILMVSWEYPPVVIGGLGRHVHHLA
Mb1244c|M.bovis_AF2122/97 ------------------------MRVAMLTREYPPEVYGGAGVHVTELV
Rv1212c|M.tuberculosis_H37Rv ------------------------MRVAMLTREYPPEVYGGAGVHVTELV
Mflv_2191|M.gilvum_PYR-GCK -----------------------------MTREYPPEVYGGAGVHVTELV
Mvan_4504|M.vanbaalenii_PYR-1 ------------------------MRVAMMTREYPPEVYGGAGVHVTELV
TH_0550|M.thermoresistible__bu ------------------------MRVAMMTREYPPEVYGGAGVHVTELV
MAB_1019c|M.abscessus_ATCC_199 ----------------------------MTGSEWFSSLPGGLNRYFTDLF
MMAR_4514|M.marinum_M ---------------MNSVGVPTPQDRLRVLVVGPAPAAATSRGGMATVI
MAV_1137|M.avium_104 --------------------------MIAVTHVGPDRYSIGGTQSVIRVI
MSMEG_5951|M.smegmatis_MC2_155 -----------------------MRILQVVTLFSPDGLYGGPTRVALNQS
MLBr_01715|M.leprae_Br4923 TALAAAGHDVVVLSRRPSGTDPCTHPTSDEISEGVRVIAAAQDPHEFTFS
MUL_1919|M.ulcerans_Agy99 TALVAAGHEVVVLSRRPSGTDPSTHPSSDLISEGVRVIAAAQDPHEFSFG
Mb1244c|M.bovis_AF2122/97 AYLRRLCAVDVHCMGAP------------------RPGAFAYRPDPRLGS
Rv1212c|M.tuberculosis_H37Rv AYLRRLCAVDVHCMGAP------------------RPGAFAYRPDPRLGS
Mflv_2191|M.gilvum_PYR-GCK AQLRRLCEVDVHCMGAP------------------RPDAMVAATDPALAG
Mvan_4504|M.vanbaalenii_PYR-1 AQLRHLCEVDVHCMGTP------------------RPGVTVAQPDAALVG
TH_0550|M.thermoresistible__bu AQLRHLCAVDVLCMGAP------------------RVDAFAARPDPTLKG
MAB_1019c|M.abscessus_ATCC_199 TALRTRGDIELSAAAFG----------------------VPSDGGSSWGG
MMAR_4514|M.marinum_M ALMAAHPDPHIHITAVP-------------------TFIDGPLWPRLMLG
MAV_1137|M.avium_104 HDNNIGADRIRVLSTWN-----------------------GPNQVKNLWL
MSMEG_5951|M.smegmatis_MC2_155 AELAGRGHEVTIAGAARG----------------YEALPSELNGVPVKLF
MLBr_01715|M.leprae_Br4923 NDMMAWTLAMGHAMIRTGLSLTRHSSDLPWRPDVVHAHDWLVAHPAITLA
MUL_1919|M.ulcerans_Agy99 SDMMAWTLAMGHAMVRAGLTLSGPGAEQPWQPDIVHAHDWLVAHPAIALA
Mb1244c|M.bovis_AF2122/97 ANAALSTLSADLVMANAASAAT-----------VVHSHTWYTALAGHLAA
Rv1212c|M.tuberculosis_H37Rv ANAALSTLSADLVMANAASAAT-----------VVHSHTWYTALAGHLAA
Mflv_2191|M.gilvum_PYR-GCK ANPALTTLSADLNMVNAAAQAQ-----------VVHSHTWYAGMAGHLSA
Mvan_4504|M.vanbaalenii_PYR-1 ANPALATLSADLNMVNSASAAT-----------VVHSHTWYAGMAGHLAA
TH_0550|M.thermoresistible__bu ANAALSTLSADLHLVNAAGAAT-----------VVHSHTWYTGLAGHLAA
MAB_1019c|M.abscessus_ATCC_199 TGGSTRSRVLAAFNDRSGLQQPG----------ILDRHFCLYGPAAIGWG
MMAR_4514|M.marinum_M VRGMLRATWLVLRKRADVLHVH-----------LAHGGSVIRKALPLLAA
MAV_1137|M.avium_104 TARAGTTLARSAAGSIVHFHVS-------------NGGAWLREGPLIRLA
MSMEG_5951|M.smegmatis_MC2_155 AATNILRRSGFAWTYAPGLTSWLRRNWREFDTVHVHLARDLVTMPVAAVV
.
MLBr_01715|M.leprae_Br4923 QFYDVPMVSTIHATEAGR-HSGWVSGALSRQVHAVESWLVRESDSLITCS
MUL_1919|M.ulcerans_Agy99 DYYDVPMVSTIHATEAGR-HSGWVSGDLSRQVHAVESWLVRESDSLITCS
Mb1244c|M.bovis_AF2122/97 ILYDIPHILTAHSLEPLRPWKKEQLGGGYQVSTWVEQTAVLAANAVIAVS
Rv1212c|M.tuberculosis_H37Rv ILYDIPHVLTAHSLEPLRPWKKEQLGGGYQVSTWVEQTAVLAANAVIAVS
Mflv_2191|M.gilvum_PYR-GCK LLYGVPHVLTAHSLEPMRPWKAEQLGGGYRISSWVEKTAVEAADAVIAVS
Mvan_4504|M.vanbaalenii_PYR-1 LLYGVPHVLTAHSLEPMRPWKAEQLGGGYRISSWVEKTAVEAADAVIAVS
TH_0550|M.thermoresistible__bu LLYGIPHVLTAHSLEPMRPWKAEQLGGGYRISSWVERTAVEAADAVIAVS
MAB_1019c|M.abscessus_ATCC_199 TRS--RLVVHFHGPWAAESRFAGAGPLRARAKYVVERLRYAGAERVIVLS
MMAR_4514|M.marinum_M RLTGTPAIVHAHSYDFGGWFDQLAPPARAAVR------RMLAADHWVVLG
MAV_1137|M.avium_104 GAKGFRVIVTLHGSDFPEFARSRPR---------FVAATLRHADKVILLS
MSMEG_5951|M.smegmatis_MC2_155 RRRGIPYVLQTHGMVVPTNHSLATP-----LDRMWTHDILRHARAVFFLD
: *. : . .
MLBr_01715|M.leprae_Br4923 ASMCNEIIELFGPG-LAEITVIRNGIDPARWP----------FAARRART
MUL_1919|M.ulcerans_Agy99 GSMSDEITELFGPG-LAETAVIRNGIDVARWP----------FAVRKPRT
Mb1244c|M.bovis_AF2122/97 SAMRNDMLRVYPSLDPNLVHVIRNGIDTETWYPAGPARTGSVLAELGVDP
Rv1212c|M.tuberculosis_H37Rv SAMRNDMLRVYPSLDPNLVHVIRNGIDTETWYPAGPARTGSVLAELGVDP
Mflv_2191|M.gilvum_PYR-GCK AGMREDVLHAYPTLDPSRVHVVLNGIDTDKWRPVDAGGDESVLTELGVDL
Mvan_4504|M.vanbaalenii_PYR-1 SGMRADVLRTYPALDPERVHVVRNGIDTEVWYPAEPDTDESVLAKLGVDP
TH_0550|M.thermoresistible__bu SGMRADVLRTYPAVDPARVHVVRNGIDTDVWYPAPPDPQESVLAELGVDP
MAB_1019c|M.abscessus_ATCC_199 DRFRDVLVEDYRIP-TDRIEVIPPGVDLDRFG---------VLPRLDAPT
MMAR_4514|M.marinum_M ERHVQEYASRLRLP-TSRISVLPNAVRIPNTP------------VNQLGV
MAV_1137|M.avium_104 EQARAALLEVAPTV---RTAVVPNPIVVDEEAP-------------GAGS
MSMEG_5951|M.smegmatis_MC2_155 SVEREQLIAVAGPD----LRLVELGNGVPEYP---------TAHSGRTLG
::
MLBr_01715|M.leprae_Br4923 GPAELLYVGRLEYEKGVHDVIAALPRIRRS-YPGTTLTIAGEGTQQDWLV
MUL_1919|M.ulcerans_Agy99 GPPELLYVGRLEYEKGVHNAIAALPRIRRA-HPGTTLTIAGEGTQQDWLV
Mb1244c|M.bovis_AF2122/97 NRPMAVFVGRITRQKGVVHLVTAAHRFR----SDVQLVLCAGAADTPEVA
Rv1212c|M.tuberculosis_H37Rv NRPMAVFVGRITRQKGVVHLVTAAHRFR----SDVQLVLCAGAADTPEVA
Mflv_2191|M.gilvum_PYR-GCK SRPIVAFVGRITRQKGVAHLVAAAHHFD----PGIQLVLCAGAPDTPEIA
Mvan_4504|M.vanbaalenii_PYR-1 TRPVVAFVGRITRQKGVAHLVAAAHHFA----PEVQLVLCAGAPDTPEIA
TH_0550|M.thermoresistible__bu GRPIVAFVGRITRQKGVAHLLAAAHRFD----PGIQLVLCAGAPDTPEIA
MAB_1019c|M.abscessus_ATCC_199 GRRTVLCVRRLEHRMGIHRLIESWPTVVSA-HPDACLMIVGTGTAEKDLR
MMAR_4514|M.marinum_M QRVHAVALGRLGVRKGSYDLIDAVAALDET-VRNRLLATLAGDGDVAQVR
MAV_1137|M.avium_104 TPPVVLFAGTVGRRKGVDRLVAAWKLLLAEGIEGRCRIIGPIDDYIPPAT
MSMEG_5951|M.smegmatis_MC2_155 RAPEVLFAARMHARKRPVVFIEMARELLASGMDARFTLVGPDEGEGPAIR
: . : .
MLBr_01715|M.leprae_Br4923 DQARKYKVIKATRFVGHLNHNELLA------ALQRADAAVLP-SHYEPFG
MUL_1919|M.ulcerans_Agy99 EQARKHRVLKATKFLGHLEHAELLT------LLHRADAAVFP-SHYEPFG
Mb1244c|M.bovis_AF2122/97 DEVRVAVAELARNRTGVFWIQDRLTIGQLREILSAATVFVCP-SVYEPLG
Rv1212c|M.tuberculosis_H37Rv DEVRVAVAELARNRTGVFWIQDRLTIGQLREILSAATVFVCP-SVYEPLG
Mflv_2191|M.gilvum_PYR-GCK EEVASAVQRLAEARTGVFWVREMLPQPKIDEILSAATTFVCP-SVYEPLG
Mvan_4504|M.vanbaalenii_PYR-1 EEVASAVQALSQARTGVFWVREMLPTPKIREILSAATTFVCP-SVYEPLG
TH_0550|M.thermoresistible__bu AEITAAVGELARRRTGVFWVRDMLPIGKIREILSAATVFVCP-SVYEPLG
MAB_1019c|M.abscessus_ATCC_199 AQVAAAGLDDSVHFTGRVDDLTLTQ------LYTLADFTVVPSVALEGFG
MMAR_4514|M.marinum_M AAVAKAGLGETIDVVGWLNPMARDE------LLRRAQIFVLP-SRNEGLP
MAV_1137|M.avium_104 ERLTVEGPIPPDRVR---------------ALLRSVRVVALP-SFAEGMP
MSMEG_5951|M.smegmatis_MC2_155 AALGGDPRITWEGALSPEAIPAR---------MAEADVYVLP-SVREPFP
. . * * :
MLBr_01715|M.leprae_Br4923 LVALEAAAAGTPLVTSNIGGLGEAVINGQTGVSCPPRD------IAELAA
MUL_1919|M.ulcerans_Agy99 LVALEAAAAGTPLVTSNIGGLGEAVIDGVTGVSCPPRD------VAALAA
Mb1244c|M.bovis_AF2122/97 IVNLEAMACATAVVASDVGGIPEVVADGITGSLVHYDADDATGYQARLAE
Rv1212c|M.tuberculosis_H37Rv IVNLEAMACATAVVASDVGGIPEVVADGITGSLVHYDADDATGYQARLAE
Mflv_2191|M.gilvum_PYR-GCK IVNLEAMACATAVVASDVGGIPEVVADGQTGLLVHYDAKDTATFERQLAE
Mvan_4504|M.vanbaalenii_PYR-1 IVNLEAMACATAVVASDVGGIPEVVVDQRTGLLVHYDPDDTASFERGLAE
TH_0550|M.thermoresistible__bu IVNLEAMACGTAVVASDVGGIPEVVSDHRTGLLVHYDAGDTEMYERRLAE
MAB_1019c|M.abscessus_ATCC_199 LIALESLATGRPAVVTDCGGLPDAVRGLDSSLIVPADN--AEALAARLVS
MMAR_4514|M.marinum_M MALLEAMANGLAPVTTTAGSIGEVVTDGVNGLLVGPAH------ADQLAH
MAV_1137|M.avium_104 MILTEALAGARPFVATPVGGTAQIAPD--PGMLVPVDD------VPALAD
MSMEG_5951|M.smegmatis_MC2_155 MSVLEAMSVGLPVVVTDDCGLAPIIEQCGCGAVTDPSVS-------GLAA
: *: : . . *.: . . *.
MLBr_01715|M.leprae_Br4923 MVCTVLEDPDAAQQRALAARERLTSDFDWQTVAQQTAQVYLAAKRRERQP
MUL_1919|M.ulcerans_Agy99 AVCGVLDDPAAAQQRARAARERLNSNFDWQTVAEQTAQVYLAAKRGERQP
Mb1244c|M.bovis_AF2122/97 AVNALVADPATAERYGHAGRQRCIQEFSWAYIAEQTLDIYRKVCA-----
Rv1212c|M.tuberculosis_H37Rv AVNALVADPATAERYGHAGRQRCIQEFSWAYIAEQTLDIYRKVCA-----
Mflv_2191|M.gilvum_PYR-GCK AVNSLVADPQRAREYGVAGRQRCIDEFSWARIAEQTLQIYRSVTA-----
Mvan_4504|M.vanbaalenii_PYR-1 AVNSLVADPQRARRYGVDGRQRCIDEFSWAHIAEQTLQIYRKVLN-----
TH_0550|M.thermoresistible__bu AVNTLVSEPDRARQYGQAGRDRCIREFSWAHIAEQTLQIYRQVAG-----
MAB_1019c|M.abscessus_ATCC_199 ALDGALPDPAQCRQHAES--------FSWAAAAQRHHAVYAELSA-----
MMAR_4514|M.marinum_M ALGALVTDENLRARLGGAARER-AGEFGLDRWYQQLTRLWASLAGDPHPS
MAV_1137|M.avium_104 AIGRYLRDPELAQRDGLRGQQHIAATRSPRVIDAELRRIYQGCDVAAG--
MSMEG_5951|M.smegmatis_MC2_155 AVGAILRDRAHTKSIGERGRETVVERFGMRPVGDRLVSTYSDALVGAP--
: : : . . . :
MLBr_01715|M.leprae_Br4923 QPRLPIVEHALPDR
MUL_1919|M.ulcerans_Agy99 LPRLPIVEHALPDR
Mb1244c|M.bovis_AF2122/97 --------------
Rv1212c|M.tuberculosis_H37Rv --------------
Mflv_2191|M.gilvum_PYR-GCK --------------
Mvan_4504|M.vanbaalenii_PYR-1 --------------
TH_0550|M.thermoresistible__bu --------------
MAB_1019c|M.abscessus_ATCC_199 --------------
MMAR_4514|M.marinum_M RR------------
MAV_1137|M.avium_104 --------------
MSMEG_5951|M.smegmatis_MC2_155 --------------