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MRILQVVTLFSPDGLYGGPTRVALNQSAELAGRGHEVTIAGAARGYEALPSELNGVPVKLFAATNILRRS GFAWTYAPGLTSWLRRNWREFDTVHVHLARDLVTMPVAAVVRRRGIPYVLQTHGMVVPTNHSLATPLDRM WTHDILRHARAVFFLDSVEREQLIAVAGPDLRLVELGNGVPEYPTAHSGRTLGRAPEVLFAARMHARKRP VVFIEMARELLASGMDARFTLVGPDEGEGPAIRAALGGDPRITWEGALSPEAIPARMAEADVYVLPSVRE PFPMSVLEAMSVGLPVVVTDDCGLAPIIEQCGCGAVTDPSVSGLAAAVGAILRDRAHTKSIGERGRETVV ERFGMRPVGDRLVSTYSDALVGAP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_5951 | - | - | 100% (374) | glycosyl transferase, group 1, putative |
M. smegmatis MC2 155 | MSMEG_4253 | - | 6e-10 | 25.72% (311) | glycosyl transferase, group 1 family protein |
M. smegmatis MC2 155 | MSMEG_6484 | - | 4e-09 | 28.67% (143) | glycosyl transferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3058 | - | 7e-12 | 25.19% (401) | transferase |
M. gilvum PYR-GCK | Mflv_2961 | - | 6e-11 | 26.19% (294) | glycosyl transferase, group 1 |
M. tuberculosis H37Rv | Rv3032 | - | 7e-12 | 25.19% (401) | transferase |
M. leprae Br4923 | MLBr_00886 | - | 5e-10 | 25.84% (329) | putative glycosyl transferase |
M. abscessus ATCC 19977 | MAB_3366 | - | 1e-09 | 25.50% (404) | glycosyltransferase |
M. marinum M | MMAR_4505 | - | 3e-11 | 28.21% (195) | glycosyltransferase |
M. avium 104 | MAV_1137 | - | 2e-15 | 29.27% (287) | glycosyl transferase, group 1 family protein |
M. thermoresistible (build 8) | TH_2191 | - | 1e-11 | 24.62% (398) | POSSIBLE TRANSFERASE |
M. ulcerans Agy99 | MUL_3104 | - | 4e-12 | 25.00% (380) | glycosyl transferase |
M. vanbaalenii PYR-1 | Mvan_3033 | - | 4e-12 | 25.68% (366) | glycosyl transferase, group 1 |
CLUSTAL 2.0.9 multiple sequence alignment MUL_3104|M.ulcerans_Agy99 -------------------------------------------------- Mvan_3033|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb3058|M.bovis_AF2122/97 -------------------------------------------------- Rv3032|M.tuberculosis_H37Rv -------------------------------------------------- TH_2191|M.thermoresistible__bu -------------------------------------------------- MAB_3366|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_2961|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00886|M.leprae_Br4923 -------------------------------------------------- MSMEG_5951|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1137|M.avium_104 -------------------------------------------------- MMAR_4505|M.marinum_M MTEEMDRAYLQRPVGDLAPLPAERSLAVLIVIGNGHDPVQSCLHSVAEQL MUL_3104|M.ulcerans_Agy99 -------------------------------------------------- Mvan_3033|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb3058|M.bovis_AF2122/97 -------------------------------------------------- Rv3032|M.tuberculosis_H37Rv -------------------------------------------------- TH_2191|M.thermoresistible__bu -------------------------------------------------- MAB_3366|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_2961|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00886|M.leprae_Br4923 -------------------------------------------------- MSMEG_5951|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1137|M.avium_104 -------------------------------------------------- MMAR_4505|M.marinum_M PGLPVYVYDNSGQGYPGRQELAAGHPAVHWISGPADVGFAAACNALAQRS MUL_3104|M.ulcerans_Agy99 -------------------------------------------------- Mvan_3033|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb3058|M.bovis_AF2122/97 -------------------------------------------------- Rv3032|M.tuberculosis_H37Rv -------------------------------------------------- TH_2191|M.thermoresistible__bu -------------------------------------------------- MAB_3366|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_2961|M.gilvum_PYR-GCK -------------------------------------------------- MLBr_00886|M.leprae_Br4923 -------------------------------------------------- MSMEG_5951|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1137|M.avium_104 -------------------------------------------------- MMAR_4505|M.marinum_M PGDSDLLLLKADARLRGPLTRTRQLLRQPGVAAVSPLVRDEAAPDRPPWD MUL_3104|M.ulcerans_Agy99 ---------------------MRVVQVANFYGPRS--------------- Mvan_3033|M.vanbaalenii_PYR-1 ---------------------MRVVQVANFYGPRS--------------- Mb3058|M.bovis_AF2122/97 ---------------------MRILMVSWEYPPVVI-------------- Rv3032|M.tuberculosis_H37Rv ---------------------MRILMVSWEYPPVVI-------------- TH_2191|M.thermoresistible__bu ---------------------MKILMVSWEYPPVVV-------------- MAB_3366|M.abscessus_ATCC_1997 ---------------------MRILMVSWEYPPVVI-------------- Mflv_2961|M.gilvum_PYR-GCK ----------------MGGLVKRILLVTNDFPPRR--------------- MLBr_00886|M.leprae_Br4923 --------------------MSRVLLVTNDFPPRR--------------- MSMEG_5951|M.smegmatis_MC2_155 ---------------------MRILQVVTLFSPDGLY------------- MAV_1137|M.avium_104 -----------------------MIAVTHVGPDRYSI------------- MMAR_4505|M.marinum_M IATQRLTLVRGVVEATGLSSWLRATRISPLYPQRPRESQSVSGYLKATCL : MUL_3104|M.ulcerans_Agy99 ----------GGLRTAVDRLG------AEYCASG-HEVFLIV-------P Mvan_3033|M.vanbaalenii_PYR-1 ----------GGLRTAVDRLG------AEYCAAG-HTVFLIV-------P Mb3058|M.bovis_AF2122/97 ----------GGLGRHVHHLS------TALAAAG-HDVVVLSRCPSGTDP Rv3032|M.tuberculosis_H37Rv ----------GGLGRHVHHLS------TALAAAG-HDVVVLSRCPSGTDP TH_2191|M.thermoresistible__bu ----------GGLGRHVYHLS------TALAAAG-HEVVVLSRRPTGTDP MAB_3366|M.abscessus_ATCC_1997 ----------GGLGRHVHHLS------TELAAAG-HDVVVLTRRPSGTDP Mflv_2961|M.gilvum_PYR-GCK ----------GGIQSYLEALV------GHLVASGDHTLTVYAPKWKG--- MLBr_00886|M.leprae_Br4923 ----------GGIQSYLGEFV------DRLINIGSHDVMVYAPQWTG--- MSMEG_5951|M.smegmatis_MC2_155 ----------GGPTRVALNQS------AELAGRG-HEVTIAGAARGYEAL MAV_1137|M.avium_104 ----------GGTQSVIRVIH------DNNIGADRIRVLSTWNG------ MMAR_4505|M.marinum_M AISRAAWNAIGGFDEEYLNHGGPADWQARARAAGWRVLLADELGAQQGGA ** . : MUL_3104|M.ulcerans_Agy99 GAHTG--QRRLDTGVVRISLPANLIPLTG-----------GYRAVMPGRV Mvan_3033|M.vanbaalenii_PYR-1 GPHPE--RVTLPSGVVRICLPARLIPYTG-----------GYRAVHPGPV Mb3058|M.bovis_AF2122/97 STHPS--SDEVTEGVRVIAAAQDPHEFTFGNDMMAWTLAMGHAMIRAGLR Rv3032|M.tuberculosis_H37Rv STHPS--SDEVTEGVRVIAAAQDPHEFTFGNDMMAWTLAMGHAMIRAGLR TH_2191|M.thermoresistible__bu STHPS--TDEVRDGVRVLAAAQDPHEFDFGRDMMAWTLAMGHSMVRAGLA MAB_3366|M.abscessus_ATCC_1997 SSHPT--SDEISEGVRVVAAAEDPHDFDFGTDMMAWTLAMGHAMVRAGLA Mflv_2961|M.gilvum_PYR-GCK APDYD--AVAAATGYEVVRHPG--------------------TLMLPEPT MLBr_00886|M.leprae_Br4923 ADTFD--NAAHDGGYQVVRHPG--------------------TLMLPGPA MSMEG_5951|M.smegmatis_MC2_155 PSELNGVPVKLFAATNILRRSG------------------FAWTYAPGLT MAV_1137|M.avium_104 PNQVKNLWLTARAGTTLARSAA-------------------------GSI MMAR_4505|M.marinum_M PPTGAETGPTVTAGERRRTRDVIRANDALLLEHQCSVHHADAYLATTKVL . MUL_3104|M.ulcerans_Agy99 RELLG------------ALDPDAVEVSDRLTLR-------SLGCWGRERG Mvan_3033|M.vanbaalenii_PYR-1 IALLA------------ELRPDALEVSDRLTLR-------SLGPWGRRHG Mb3058|M.bovis_AF2122/97 LKKLG---------TDRSWRPDVVHAHDWLVAH-------PAIALAQFYD Rv3032|M.tuberculosis_H37Rv LKKLG---------TDRSWRPDVVHAHDWLVAH-------PAIALAQFYD TH_2191|M.thermoresistible__bu LGLRGGT-------GGTPWQPDVVHAHDWLVAH-------PAIALAEFFD MAB_3366|M.abscessus_ATCC_1997 LGLKG----------SGDWRPDVVHAHDWLVAH-------PAIALAEHFD Mflv_2961|M.gilvum_PYR-GCK VVLRMR-------------KIIAERGIDTVWFG-------AAAPLALMAP MLBr_00886|M.leprae_Br4923 VDARMR-------------RLIVDHGIDTVWFG-------SAAPLALLAP MSMEG_5951|M.smegmatis_MC2_155 SWLRRN---------WREFDTVHVHLARDLVTM-------PVAAVVRRRG MAV_1137|M.avium_104 VHFHVS------------------NGGAWLREG-------PLIRLAGAKG MMAR_4505|M.marinum_M QRLRRAQRRAIRNTGAGKRRPAIVIATNRLVYGGAERQKALLAAELDRRG : MUL_3104|M.ulcerans_Agy99 ITTVMISHERLDRLVGQVLPHRAAQRLADFANRRTAANYDTVVCTTAF-- Mvan_3033|M.vanbaalenii_PYR-1 VSTVMISHERLDRLVGQILPVPIARAVADVANRRTAANYDAVVCTTAF-- Mb3058|M.bovis_AF2122/97 VPMVSTIHATEAGRHSGWVSGALSRQVHAVESWLVRESDSLITCSASM-- Rv3032|M.tuberculosis_H37Rv VPMVSTIHATEAGRHSGWVSGALSRQVHAVESWLVRESDSLITCSASM-- TH_2191|M.thermoresistible__bu VPLVSTIHATEAGRHSGWVSGPISRQVHAVESWLVRDSDSLITCSASM-- MAB_3366|M.abscessus_ATCC_1997 VPLVSTLHATEAGRHSGWVSGRISRQVHSVEWWLARESDSLITCSASM-- Mflv_2961|M.gilvum_PYR-GCK LARAAGARRVIASTHGHEVGWSMLPLARNALRRIGNDTDVVTYISAYT-- MLBr_00886|M.leprae_Br4923 CARKAGATRVLASTHGHEVGWSMLPVARSVLRRIGDVTDVVTFVSRYT-- MSMEG_5951|M.smegmatis_MC2_155 IPYVLQTHGMVVPTN----HSLATPLDRMWTHDILRHARAVFFLDSVE-- MAV_1137|M.avium_104 FRVIVTLHGSDFPEFARSRPRFVAATLR--------HADKVILLSEQA-- MMAR_4505|M.marinum_M YPVTIVCVQRFGPLIKEIPDTVRVVRQPWWAPIVDVGPGPAVLISGDTNT MUL_3104|M.ulcerans_Agy99 -----------------------------------------AREEFDRIG Mvan_3033|M.vanbaalenii_PYR-1 -----------------------------------------AREEFDRIG Mb3058|M.bovis_AF2122/97 -----------------------------------------NDEITELFG Rv3032|M.tuberculosis_H37Rv -----------------------------------------NDEITELFG TH_2191|M.thermoresistible__bu -----------------------------------------SEEITELFG MAB_3366|M.abscessus_ATCC_1997 -----------------------------------------LDEVTQLFG Mflv_2961|M.gilvum_PYR-GCK -----------------------------------------RGRFASAFG MLBr_00886|M.leprae_Br4923 -----------------------------------------RSRVTAAFG MSMEG_5951|M.smegmatis_MC2_155 -----------------------------------------REQLIAVAG MAV_1137|M.avium_104 -----------------------------------------RAALLEVAP MMAR_4505|M.marinum_M ETGFATLWRAAGRRRRWLVAAHIPPLEVGPIYSGPLTAAMRRADGFIVLA MUL_3104|M.ulcerans_Agy99 --ATNTLTVPLGVDLQTFHPR----RRCPLVRQRFATPRQLLLIHCGRLS Mvan_3033|M.vanbaalenii_PYR-1 --ATNVATVPLGVDLEQFHPR----RRSAEVRRRWAAPEQSLLVHCGRLS Mb3058|M.bovis_AF2122/97 PGLAEITVIRNGIDAARWPFA----ARRPRTG-------PAELLYVGRLE Rv3032|M.tuberculosis_H37Rv PGLAEITVIRNGIDAARWPFA----ARRPRTG-------PAELLYVGRLE TH_2191|M.thermoresistible__bu PGLSEIRVIRNGIDVAQWPFA----RRSPRSG-------PPRLLYVGRLE MAB_3366|M.abscessus_ATCC_1997 PELPQVHVIRNGIDVTRWVFA----PRPPADGT------PPVLLFVGRLE Mflv_2961|M.gilvum_PYR-GCK P-DAALEHVPPGVDTDRFVPDE---VARAEMRARYRLGNRPVVACVSRLV MLBr_00886|M.leprae_Br4923 P-RAALEYLPPGVDADRFRPDP---ASRAELRNRYRLGERPTVVCLARLV MSMEG_5951|M.smegmatis_MC2_155 P---DLRLVELGNGVPEYPTAH---SGRTLGR-------APEVLFAARMH MAV_1137|M.avium_104 TVRTAVVPNPIVVDEEAPGAG----------------STPPVVLFAGTVG MMAR_4505|M.marinum_M QRHWDMLTPYHRLGGPRFVAPNGVAVTDRPAGRSRPAGAPPHLVMLSRIV . : . : MUL_3104|M.ulcerans_Agy99 VEKHVDRSIGALAALCDAGVDARFVIVGEGPLRARLQRQAAG----LPVD Mvan_3033|M.vanbaalenii_PYR-1 VEKQPHRSIEAVAALRDSGIDARLVVVGEGPLRARLQRQAVR----LPVE Mb3058|M.bovis_AF2122/97 YEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQQDWLIDQARKHRVLRATR Rv3032|M.tuberculosis_H37Rv YEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQQDWLIDQARKHRVLRATR TH_2191|M.thermoresistible__bu YEKGVQDAIAALPRIRRTHPGTTLTIAGTGTQHEWLVEQARKHKVLKATR MAB_3366|M.abscessus_ATCC_1997 YEKGIHDAIAALPKIRRAHPGTVLAVAGDGTQQDWLLEQARKYKVVKSVQ Mflv_2961|M.gilvum_PYR-GCK PRKGQDMLIRALPAIRQRAPGAALVIVGGGPYRTSLHRLAHDFGVADHVV MLBr_00886|M.leprae_Br4923 PRKGQDMLIRALPSIRQRADGAALMIVGGGPYLGTLRKLAQGCGVADHVI MSMEG_5951|M.smegmatis_MC2_155 ARKRPVVFIEMARELLASGMDARFTLVGPDEGEGPAIRAALGGD--PRIT MAV_1137|M.avium_104 RRKGVDRLVAAWKLLLAEGIEGRCRIIG--PIDDYIPPATER------LT MMAR_4505|M.marinum_M EHKNPHLLIEALSGIT--ELPWTLSIFGDGPDRERLQARTPER-LRDRVH .* : : : * : MUL_3104|M.ulcerans_Agy99 FTGFVTHRDTVAQLLASADIPLAPG-------PHETFGLAALESLACGTP Mvan_3033|M.vanbaalenii_PYR-1 FTGYIGCRDTVADILASADVALAPG-------PHETFGLAALEALACGTP Mb3058|M.bovis_AF2122/97 FVGHLDH-TELLALLHRADAAVLPS-------HYEPFGLVALEAAAAGTP Rv3032|M.tuberculosis_H37Rv FVGHLDH-TELLALLHRADAAVLPS-------HYEPFGLVALEAAAAGTP TH_2191|M.thermoresistible__bu FVGQLGH-EALLRQLHTADAAVLPS-------HYEPFGIVALEAAATGAP MAB_3366|M.abscessus_ATCC_1997 FLGTLDH-SELLHWLHHADAILLPS-------HYEPFGIVALEAAAAGTP Mflv_2961|M.gilvum_PYR-GCK FTDGVPG-EELPAHHAMADVFAMPCRTRGSGLDVEGLGIVYLEASSTGVP MLBr_00886|M.leprae_Br4923 FAGGVAA-VEVPAHYTLADVFAMPCRTRGGGMDVEGLGIVFLEASATGVP MSMEG_5951|M.smegmatis_MC2_155 WEGALSP-EAIPARMAEADVYVLPS-------VREPFPMSVLEAMSVGLP MAV_1137|M.avium_104 VEGPIPP-DRVRALLRSVRVVALPS-------FAEGMPMILTEALAGARP MMAR_4505|M.marinum_M WRGWSPG---PGPALADADLLCVPS-------RSEAFPLVILEAMARAVP . . * * : : *: : . * MUL_3104|M.ulcerans_Agy99 AVVSRTSALSEIITTDSG--ASADNDPAAIAAAVRTIVGWPE--RQRRSS Mvan_3033|M.vanbaalenii_PYR-1 AVVSRTSALAEILTDDSG--ATADNDPHAIAHAVSTVLTRPE--HQRRHS Mb3058|M.bovis_AF2122/97 LVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVLDDPAAAQRRARA Rv3032|M.tuberculosis_H37Rv LVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVLDDPAAAQRRARA TH_2191|M.thermoresistible__bu LVTSTAGGLGEAVIDGVTGKSFKPRDIAGLTAAVRAVLDDPEGAQQRAVA MAB_3366|M.abscessus_ATCC_1997 LVTSTVGGLGEAVIDGETGMSFAPRDVAGIAEAVTRTLDDPAAAAERAVA Mflv_2961|M.gilvum_PYR-GCK VVAGRSGGAPETVRDGETGLVVDGWDVGAIAASVGELLADPARAAAMGAA MLBr_00886|M.leprae_Br4923 VIAGKSGGAPEAVQHNKTGLVVDGRSVNMVADAVTELLTDRDRAAAMGAA MSMEG_5951|M.smegmatis_MC2_155 VVVTDDCGLAPIIEQCGCGAVTDP-SVSGLAAAVGAILRDRAHTKSIGER MAV_1137|M.avium_104 FVATPVGGTAQIAP--DPGMLVPVDDVPALADAIGRYLRDPELAQRDGLR MMAR_4505|M.marinum_M VAASAICAVPEMLDFGGAGFVVEPVTVSAWRERLAQILADPGELPAVGQR . . : : MUL_3104|M.ulcerans_Agy99 ARRR-AEMFTWQGWPP--PGC------------------------- Mvan_3033|M.vanbaalenii_PYR-1 ARQR-AEQFTWPRSAAGMLGALGAR--------------------- Mb3058|M.bovis_AF2122/97 ARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPIVEHALPDR Rv3032|M.tuberculosis_H37Rv ARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPIVEHALPDR TH_2191|M.thermoresistible__bu ARERLTADFDWHSVAAETAQVYLAAKRREREPLPRRLIVEHALPDR MAB_3366|M.abscessus_ATCC_1997 ARARLTADFDWATVADETAQVYLAAKRREREPLGRSVIVERPLPDR Mflv_2961|M.gilvum_PYR-GCK GRQWAVDNWRWSLQAERLARLL------------------------ MLBr_00886|M.leprae_Br4923 GRHWVTAEWRWDTLAARLADLLCGNDSR------------------ MSMEG_5951|M.smegmatis_MC2_155 GRETVVERFGMRPVGDRLVSTYSDALVGAP---------------- MAV_1137|M.avium_104 GQQHIAATRSPRVIDAELRRIYQGCDVAAG---------------- MMAR_4505|M.marinum_M GFARMRKHYTVAAMTDAYLDAIHAVL-------------------- .