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M. smegmatis MC2 155 MSMEG_5951 (-)

annotation: glycosyl transferase, group 1, putative
coordinates: 6012352 - 6013476
length: 374

MRILQVVTLFSPDGLYGGPTRVALNQSAELAGRGHEVTIAGAARGYEALPSELNGVPVKLFAATNILRRS
GFAWTYAPGLTSWLRRNWREFDTVHVHLARDLVTMPVAAVVRRRGIPYVLQTHGMVVPTNHSLATPLDRM
WTHDILRHARAVFFLDSVEREQLIAVAGPDLRLVELGNGVPEYPTAHSGRTLGRAPEVLFAARMHARKRP
VVFIEMARELLASGMDARFTLVGPDEGEGPAIRAALGGDPRITWEGALSPEAIPARMAEADVYVLPSVRE
PFPMSVLEAMSVGLPVVVTDDCGLAPIIEQCGCGAVTDPSVSGLAAAVGAILRDRAHTKSIGERGRETVV
ERFGMRPVGDRLVSTYSDALVGAP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5951--100% (374)glycosyl transferase, group 1, putative
M. smegmatis MC2 155MSMEG_4253-6e-1025.72% (311) glycosyl transferase, group 1 family protein
M. smegmatis MC2 155MSMEG_6484-4e-0928.67% (143) glycosyl transferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3058-7e-1225.19% (401) transferase
M. gilvum PYR-GCKMflv_2961-6e-1126.19% (294) glycosyl transferase, group 1
M. tuberculosis H37RvRv3032-7e-1225.19% (401) transferase
M. leprae Br4923MLBr_00886-5e-1025.84% (329) putative glycosyl transferase
M. abscessus ATCC 19977MAB_3366-1e-0925.50% (404) glycosyltransferase
M. marinum MMMAR_4505-3e-1128.21% (195) glycosyltransferase
M. avium 104MAV_1137-2e-1529.27% (287) glycosyl transferase, group 1 family protein
M. thermoresistible (build 8)TH_2191-1e-1124.62% (398) POSSIBLE TRANSFERASE
M. ulcerans Agy99MUL_3104-4e-1225.00% (380) glycosyl transferase
M. vanbaalenii PYR-1Mvan_3033-4e-1225.68% (366) glycosyl transferase, group 1

CLUSTAL 2.0.9 multiple sequence alignment


MUL_3104|M.ulcerans_Agy99           --------------------------------------------------
Mvan_3033|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3058|M.bovis_AF2122/97            --------------------------------------------------
Rv3032|M.tuberculosis_H37Rv         --------------------------------------------------
TH_2191|M.thermoresistible__bu      --------------------------------------------------
MAB_3366|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_2961|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_00886|M.leprae_Br4923          --------------------------------------------------
MSMEG_5951|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1137|M.avium_104                --------------------------------------------------
MMAR_4505|M.marinum_M               MTEEMDRAYLQRPVGDLAPLPAERSLAVLIVIGNGHDPVQSCLHSVAEQL
                                                                                      

MUL_3104|M.ulcerans_Agy99           --------------------------------------------------
Mvan_3033|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3058|M.bovis_AF2122/97            --------------------------------------------------
Rv3032|M.tuberculosis_H37Rv         --------------------------------------------------
TH_2191|M.thermoresistible__bu      --------------------------------------------------
MAB_3366|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_2961|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_00886|M.leprae_Br4923          --------------------------------------------------
MSMEG_5951|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1137|M.avium_104                --------------------------------------------------
MMAR_4505|M.marinum_M               PGLPVYVYDNSGQGYPGRQELAAGHPAVHWISGPADVGFAAACNALAQRS
                                                                                      

MUL_3104|M.ulcerans_Agy99           --------------------------------------------------
Mvan_3033|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3058|M.bovis_AF2122/97            --------------------------------------------------
Rv3032|M.tuberculosis_H37Rv         --------------------------------------------------
TH_2191|M.thermoresistible__bu      --------------------------------------------------
MAB_3366|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_2961|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_00886|M.leprae_Br4923          --------------------------------------------------
MSMEG_5951|M.smegmatis_MC2_155      --------------------------------------------------
MAV_1137|M.avium_104                --------------------------------------------------
MMAR_4505|M.marinum_M               PGDSDLLLLKADARLRGPLTRTRQLLRQPGVAAVSPLVRDEAAPDRPPWD
                                                                                      

MUL_3104|M.ulcerans_Agy99           ---------------------MRVVQVANFYGPRS---------------
Mvan_3033|M.vanbaalenii_PYR-1       ---------------------MRVVQVANFYGPRS---------------
Mb3058|M.bovis_AF2122/97            ---------------------MRILMVSWEYPPVVI--------------
Rv3032|M.tuberculosis_H37Rv         ---------------------MRILMVSWEYPPVVI--------------
TH_2191|M.thermoresistible__bu      ---------------------MKILMVSWEYPPVVV--------------
MAB_3366|M.abscessus_ATCC_1997      ---------------------MRILMVSWEYPPVVI--------------
Mflv_2961|M.gilvum_PYR-GCK          ----------------MGGLVKRILLVTNDFPPRR---------------
MLBr_00886|M.leprae_Br4923          --------------------MSRVLLVTNDFPPRR---------------
MSMEG_5951|M.smegmatis_MC2_155      ---------------------MRILQVVTLFSPDGLY-------------
MAV_1137|M.avium_104                -----------------------MIAVTHVGPDRYSI-------------
MMAR_4505|M.marinum_M               IATQRLTLVRGVVEATGLSSWLRATRISPLYPQRPRESQSVSGYLKATCL
                                                              :                       

MUL_3104|M.ulcerans_Agy99           ----------GGLRTAVDRLG------AEYCASG-HEVFLIV-------P
Mvan_3033|M.vanbaalenii_PYR-1       ----------GGLRTAVDRLG------AEYCAAG-HTVFLIV-------P
Mb3058|M.bovis_AF2122/97            ----------GGLGRHVHHLS------TALAAAG-HDVVVLSRCPSGTDP
Rv3032|M.tuberculosis_H37Rv         ----------GGLGRHVHHLS------TALAAAG-HDVVVLSRCPSGTDP
TH_2191|M.thermoresistible__bu      ----------GGLGRHVYHLS------TALAAAG-HEVVVLSRRPTGTDP
MAB_3366|M.abscessus_ATCC_1997      ----------GGLGRHVHHLS------TELAAAG-HDVVVLTRRPSGTDP
Mflv_2961|M.gilvum_PYR-GCK          ----------GGIQSYLEALV------GHLVASGDHTLTVYAPKWKG---
MLBr_00886|M.leprae_Br4923          ----------GGIQSYLGEFV------DRLINIGSHDVMVYAPQWTG---
MSMEG_5951|M.smegmatis_MC2_155      ----------GGPTRVALNQS------AELAGRG-HEVTIAGAARGYEAL
MAV_1137|M.avium_104                ----------GGTQSVIRVIH------DNNIGADRIRVLSTWNG------
MMAR_4505|M.marinum_M               AISRAAWNAIGGFDEEYLNHGGPADWQARARAAGWRVLLADELGAQQGGA
                                              **                     .   :            

MUL_3104|M.ulcerans_Agy99           GAHTG--QRRLDTGVVRISLPANLIPLTG-----------GYRAVMPGRV
Mvan_3033|M.vanbaalenii_PYR-1       GPHPE--RVTLPSGVVRICLPARLIPYTG-----------GYRAVHPGPV
Mb3058|M.bovis_AF2122/97            STHPS--SDEVTEGVRVIAAAQDPHEFTFGNDMMAWTLAMGHAMIRAGLR
Rv3032|M.tuberculosis_H37Rv         STHPS--SDEVTEGVRVIAAAQDPHEFTFGNDMMAWTLAMGHAMIRAGLR
TH_2191|M.thermoresistible__bu      STHPS--TDEVRDGVRVLAAAQDPHEFDFGRDMMAWTLAMGHSMVRAGLA
MAB_3366|M.abscessus_ATCC_1997      SSHPT--SDEISEGVRVVAAAEDPHDFDFGTDMMAWTLAMGHAMVRAGLA
Mflv_2961|M.gilvum_PYR-GCK          APDYD--AVAAATGYEVVRHPG--------------------TLMLPEPT
MLBr_00886|M.leprae_Br4923          ADTFD--NAAHDGGYQVVRHPG--------------------TLMLPGPA
MSMEG_5951|M.smegmatis_MC2_155      PSELNGVPVKLFAATNILRRSG------------------FAWTYAPGLT
MAV_1137|M.avium_104                PNQVKNLWLTARAGTTLARSAA-------------------------GSI
MMAR_4505|M.marinum_M               PPTGAETGPTVTAGERRRTRDVIRANDALLLEHQCSVHHADAYLATTKVL
                                                 .                                    

MUL_3104|M.ulcerans_Agy99           RELLG------------ALDPDAVEVSDRLTLR-------SLGCWGRERG
Mvan_3033|M.vanbaalenii_PYR-1       IALLA------------ELRPDALEVSDRLTLR-------SLGPWGRRHG
Mb3058|M.bovis_AF2122/97            LKKLG---------TDRSWRPDVVHAHDWLVAH-------PAIALAQFYD
Rv3032|M.tuberculosis_H37Rv         LKKLG---------TDRSWRPDVVHAHDWLVAH-------PAIALAQFYD
TH_2191|M.thermoresistible__bu      LGLRGGT-------GGTPWQPDVVHAHDWLVAH-------PAIALAEFFD
MAB_3366|M.abscessus_ATCC_1997      LGLKG----------SGDWRPDVVHAHDWLVAH-------PAIALAEHFD
Mflv_2961|M.gilvum_PYR-GCK          VVLRMR-------------KIIAERGIDTVWFG-------AAAPLALMAP
MLBr_00886|M.leprae_Br4923          VDARMR-------------RLIVDHGIDTVWFG-------SAAPLALLAP
MSMEG_5951|M.smegmatis_MC2_155      SWLRRN---------WREFDTVHVHLARDLVTM-------PVAAVVRRRG
MAV_1137|M.avium_104                VHFHVS------------------NGGAWLREG-------PLIRLAGAKG
MMAR_4505|M.marinum_M               QRLRRAQRRAIRNTGAGKRRPAIVIATNRLVYGGAERQKALLAAELDRRG
                                                                 :                    

MUL_3104|M.ulcerans_Agy99           ITTVMISHERLDRLVGQVLPHRAAQRLADFANRRTAANYDTVVCTTAF--
Mvan_3033|M.vanbaalenii_PYR-1       VSTVMISHERLDRLVGQILPVPIARAVADVANRRTAANYDAVVCTTAF--
Mb3058|M.bovis_AF2122/97            VPMVSTIHATEAGRHSGWVSGALSRQVHAVESWLVRESDSLITCSASM--
Rv3032|M.tuberculosis_H37Rv         VPMVSTIHATEAGRHSGWVSGALSRQVHAVESWLVRESDSLITCSASM--
TH_2191|M.thermoresistible__bu      VPLVSTIHATEAGRHSGWVSGPISRQVHAVESWLVRDSDSLITCSASM--
MAB_3366|M.abscessus_ATCC_1997      VPLVSTLHATEAGRHSGWVSGRISRQVHSVEWWLARESDSLITCSASM--
Mflv_2961|M.gilvum_PYR-GCK          LARAAGARRVIASTHGHEVGWSMLPLARNALRRIGNDTDVVTYISAYT--
MLBr_00886|M.leprae_Br4923          CARKAGATRVLASTHGHEVGWSMLPVARSVLRRIGDVTDVVTFVSRYT--
MSMEG_5951|M.smegmatis_MC2_155      IPYVLQTHGMVVPTN----HSLATPLDRMWTHDILRHARAVFFLDSVE--
MAV_1137|M.avium_104                FRVIVTLHGSDFPEFARSRPRFVAATLR--------HADKVILLSEQA--
MMAR_4505|M.marinum_M               YPVTIVCVQRFGPLIKEIPDTVRVVRQPWWAPIVDVGPGPAVLISGDTNT
                                                                                      

MUL_3104|M.ulcerans_Agy99           -----------------------------------------AREEFDRIG
Mvan_3033|M.vanbaalenii_PYR-1       -----------------------------------------AREEFDRIG
Mb3058|M.bovis_AF2122/97            -----------------------------------------NDEITELFG
Rv3032|M.tuberculosis_H37Rv         -----------------------------------------NDEITELFG
TH_2191|M.thermoresistible__bu      -----------------------------------------SEEITELFG
MAB_3366|M.abscessus_ATCC_1997      -----------------------------------------LDEVTQLFG
Mflv_2961|M.gilvum_PYR-GCK          -----------------------------------------RGRFASAFG
MLBr_00886|M.leprae_Br4923          -----------------------------------------RSRVTAAFG
MSMEG_5951|M.smegmatis_MC2_155      -----------------------------------------REQLIAVAG
MAV_1137|M.avium_104                -----------------------------------------RAALLEVAP
MMAR_4505|M.marinum_M               ETGFATLWRAAGRRRRWLVAAHIPPLEVGPIYSGPLTAAMRRADGFIVLA
                                                                                      

MUL_3104|M.ulcerans_Agy99           --ATNTLTVPLGVDLQTFHPR----RRCPLVRQRFATPRQLLLIHCGRLS
Mvan_3033|M.vanbaalenii_PYR-1       --ATNVATVPLGVDLEQFHPR----RRSAEVRRRWAAPEQSLLVHCGRLS
Mb3058|M.bovis_AF2122/97            PGLAEITVIRNGIDAARWPFA----ARRPRTG-------PAELLYVGRLE
Rv3032|M.tuberculosis_H37Rv         PGLAEITVIRNGIDAARWPFA----ARRPRTG-------PAELLYVGRLE
TH_2191|M.thermoresistible__bu      PGLSEIRVIRNGIDVAQWPFA----RRSPRSG-------PPRLLYVGRLE
MAB_3366|M.abscessus_ATCC_1997      PELPQVHVIRNGIDVTRWVFA----PRPPADGT------PPVLLFVGRLE
Mflv_2961|M.gilvum_PYR-GCK          P-DAALEHVPPGVDTDRFVPDE---VARAEMRARYRLGNRPVVACVSRLV
MLBr_00886|M.leprae_Br4923          P-RAALEYLPPGVDADRFRPDP---ASRAELRNRYRLGERPTVVCLARLV
MSMEG_5951|M.smegmatis_MC2_155      P---DLRLVELGNGVPEYPTAH---SGRTLGR-------APEVLFAARMH
MAV_1137|M.avium_104                TVRTAVVPNPIVVDEEAPGAG----------------STPPVVLFAGTVG
MMAR_4505|M.marinum_M               QRHWDMLTPYHRLGGPRFVAPNGVAVTDRPAGRSRPAGAPPHLVMLSRIV
                                                 .                            :   . : 

MUL_3104|M.ulcerans_Agy99           VEKHVDRSIGALAALCDAGVDARFVIVGEGPLRARLQRQAAG----LPVD
Mvan_3033|M.vanbaalenii_PYR-1       VEKQPHRSIEAVAALRDSGIDARLVVVGEGPLRARLQRQAVR----LPVE
Mb3058|M.bovis_AF2122/97            YEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQQDWLIDQARKHRVLRATR
Rv3032|M.tuberculosis_H37Rv         YEKGVHDAIAALPRLRRTHPGTTLTIAGEGTQQDWLIDQARKHRVLRATR
TH_2191|M.thermoresistible__bu      YEKGVQDAIAALPRIRRTHPGTTLTIAGTGTQHEWLVEQARKHKVLKATR
MAB_3366|M.abscessus_ATCC_1997      YEKGIHDAIAALPKIRRAHPGTVLAVAGDGTQQDWLLEQARKYKVVKSVQ
Mflv_2961|M.gilvum_PYR-GCK          PRKGQDMLIRALPAIRQRAPGAALVIVGGGPYRTSLHRLAHDFGVADHVV
MLBr_00886|M.leprae_Br4923          PRKGQDMLIRALPSIRQRADGAALMIVGGGPYLGTLRKLAQGCGVADHVI
MSMEG_5951|M.smegmatis_MC2_155      ARKRPVVFIEMARELLASGMDARFTLVGPDEGEGPAIRAALGGD--PRIT
MAV_1137|M.avium_104                RRKGVDRLVAAWKLLLAEGIEGRCRIIG--PIDDYIPPATER------LT
MMAR_4505|M.marinum_M               EHKNPHLLIEALSGIT--ELPWTLSIFGDGPDRERLQARTPER-LRDRVH
                                     .*     :     :          : *           :          

MUL_3104|M.ulcerans_Agy99           FTGFVTHRDTVAQLLASADIPLAPG-------PHETFGLAALESLACGTP
Mvan_3033|M.vanbaalenii_PYR-1       FTGYIGCRDTVADILASADVALAPG-------PHETFGLAALEALACGTP
Mb3058|M.bovis_AF2122/97            FVGHLDH-TELLALLHRADAAVLPS-------HYEPFGLVALEAAAAGTP
Rv3032|M.tuberculosis_H37Rv         FVGHLDH-TELLALLHRADAAVLPS-------HYEPFGLVALEAAAAGTP
TH_2191|M.thermoresistible__bu      FVGQLGH-EALLRQLHTADAAVLPS-------HYEPFGIVALEAAATGAP
MAB_3366|M.abscessus_ATCC_1997      FLGTLDH-SELLHWLHHADAILLPS-------HYEPFGIVALEAAAAGTP
Mflv_2961|M.gilvum_PYR-GCK          FTDGVPG-EELPAHHAMADVFAMPCRTRGSGLDVEGLGIVYLEASSTGVP
MLBr_00886|M.leprae_Br4923          FAGGVAA-VEVPAHYTLADVFAMPCRTRGGGMDVEGLGIVFLEASATGVP
MSMEG_5951|M.smegmatis_MC2_155      WEGALSP-EAIPARMAEADVYVLPS-------VREPFPMSVLEAMSVGLP
MAV_1137|M.avium_104                VEGPIPP-DRVRALLRSVRVVALPS-------FAEGMPMILTEALAGARP
MMAR_4505|M.marinum_M               WRGWSPG---PGPALADADLLCVPS-------RSEAFPLVILEAMARAVP
                                      .              .     *          * : :   *: : . *

MUL_3104|M.ulcerans_Agy99           AVVSRTSALSEIITTDSG--ASADNDPAAIAAAVRTIVGWPE--RQRRSS
Mvan_3033|M.vanbaalenii_PYR-1       AVVSRTSALAEILTDDSG--ATADNDPHAIAHAVSTVLTRPE--HQRRHS
Mb3058|M.bovis_AF2122/97            LVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVLDDPAAAQRRARA
Rv3032|M.tuberculosis_H37Rv         LVTSNIGGLGEAVINGQTGVSCAPRDVAGLAAAVRSVLDDPAAAQRRARA
TH_2191|M.thermoresistible__bu      LVTSTAGGLGEAVIDGVTGKSFKPRDIAGLTAAVRAVLDDPEGAQQRAVA
MAB_3366|M.abscessus_ATCC_1997      LVTSTVGGLGEAVIDGETGMSFAPRDVAGIAEAVTRTLDDPAAAAERAVA
Mflv_2961|M.gilvum_PYR-GCK          VVAGRSGGAPETVRDGETGLVVDGWDVGAIAASVGELLADPARAAAMGAA
MLBr_00886|M.leprae_Br4923          VIAGKSGGAPEAVQHNKTGLVVDGRSVNMVADAVTELLTDRDRAAAMGAA
MSMEG_5951|M.smegmatis_MC2_155      VVVTDDCGLAPIIEQCGCGAVTDP-SVSGLAAAVGAILRDRAHTKSIGER
MAV_1137|M.avium_104                FVATPVGGTAQIAP--DPGMLVPVDDVPALADAIGRYLRDPELAQRDGLR
MMAR_4505|M.marinum_M               VAASAICAVPEMLDFGGAGFVVEPVTVSAWRERLAQILADPGELPAVGQR
                                      .    .                         :   :            

MUL_3104|M.ulcerans_Agy99           ARRR-AEMFTWQGWPP--PGC-------------------------
Mvan_3033|M.vanbaalenii_PYR-1       ARQR-AEQFTWPRSAAGMLGALGAR---------------------
Mb3058|M.bovis_AF2122/97            ARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPIVEHALPDR
Rv3032|M.tuberculosis_H37Rv         ARQRLTSDFDWQTVATATAQVYLAAKRGERQPQPRLPIVEHALPDR
TH_2191|M.thermoresistible__bu      ARERLTADFDWHSVAAETAQVYLAAKRREREPLPRRLIVEHALPDR
MAB_3366|M.abscessus_ATCC_1997      ARARLTADFDWATVADETAQVYLAAKRREREPLGRSVIVERPLPDR
Mflv_2961|M.gilvum_PYR-GCK          GRQWAVDNWRWSLQAERLARLL------------------------
MLBr_00886|M.leprae_Br4923          GRHWVTAEWRWDTLAARLADLLCGNDSR------------------
MSMEG_5951|M.smegmatis_MC2_155      GRETVVERFGMRPVGDRLVSTYSDALVGAP----------------
MAV_1137|M.avium_104                GQQHIAATRSPRVIDAELRRIYQGCDVAAG----------------
MMAR_4505|M.marinum_M               GFARMRKHYTVAAMTDAYLDAIHAVL--------------------
                                    .