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MDFRTFVRILGAHWKLALTALLACTVGAAFVTALQTKHYQSSATVLISFSGATDLNEVYSGTETAQERLS SYAQIAGGHIVAERAIRQLQLPMSADDLLSQTQVKYTPKSVMFTISVKDTDPARAAALAGAMANQFSALL PTIAPNTGPNTVGAQATAGPRPEVAETTPAPGQPPEAPAAVGPTGKPWPLARATMVEPPRVPNVPVSPVP LRNMVIGFIAGLLLAIAVALTREAGDRTVRTRAKLEELSGLPTLAELPGRRGGTPRFGTDTAFDDAVRGM RTRLLRAMGPDARQVLVTGPFGGEGTTTTAMNLALALAEMGEDALLVEGDSRRHVIAGLLRVESGEGLAS ALANPAAAAEVVKPTPISRLFILASRSARRESLPPSAYLPEVVDRVVQELSSRFDRIVIDGPPVLATADT GLLSGAVPATVLVVRAKRTTADELRDALTALRAAGAHVVGTVLTDARQSLHIRAADRAYRSKVSRPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1135 | - | - | 100% (487) | chain length determinant protein |
| M. avium 104 | MAV_4824 | - | 2e-05 | 29.52% (166) | hypothetical protein MAV_4824 |
| M. avium 104 | MAV_3068 | soj | 2e-05 | 29.32% (133) | SpoOJ regulator protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3949c | parA | 1e-05 | 25.50% (251) | chromosome partitioning protein ParA |
| M. gilvum PYR-GCK | Mflv_4771 | - | 2e-51 | 28.51% (470) | lipopolysaccharide biosynthesis |
| M. tuberculosis H37Rv | Rv3918c | parA | 1e-05 | 25.50% (251) | chromosome partitioning protein ParA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4516 | - | 1e-165 | 64.26% (484) | hypothetical protein MMAR_4516 |
| M. smegmatis MC2 155 | MSMEG_5955 | - | 4e-14 | 32.22% (180) | protein-tyrosine kinase, putative |
| M. thermoresistible (build 8) | TH_3875 | - | 7e-05 | 28.57% (133) | PUTATIVE Cobyrinic acid a,c-diamide synthase |
| M. ulcerans Agy99 | MUL_3237 | - | 4e-05 | 28.47% (137) | Soj family ATPase |
| M. vanbaalenii PYR-1 | Mvan_1681 | - | 2e-54 | 29.30% (471) | lipopolysaccharide biosynthesis |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1135|M.avium_104 -MDFRTFVRILGAHWKLALTALLACTVGAAFVTALQTKHYQSSATVLISF
MMAR_4516|M.marinum_M -MDFRTFVQTLAKRWKLVVGALLACLAGATAVTAFQTKVYQSSATIFISV
Mflv_4771|M.gilvum_PYR-GCK -MNLQDFVKLLRSRWMTVCVTMVFAVMGAIAYTLLITPQYQASTRLFVST
Mvan_1681|M.vanbaalenii_PYR-1 -MNLQDFVKLLRARWITLCVALIVAVLGAVAVSMLTTPLYQASTRLFVST
MSMEG_5955|M.smegmatis_MC2_155 -MNLKSFVAAAQRFWSTYLLVAGLVLIVGAAAIMMLPVTYVSSARLMVSI
Mb3949c|M.bovis_AF2122/97 MSAPWGPVAAGPSALVRSGQASTIEPFQREMTPPTPTPEAAHNPTMNVSR
Rv3918c|M.tuberculosis_H37Rv MSAPWGPVAAGPSALVRSGQASTIEPFQREMTPPTPTPEAAHNPTMNVSR
TH_3875|M.thermoresistible__bu -----------------------------------MTDDAVTAEVVGLTG
MUL_3237|M.ulcerans_Agy99 --MPAGLPAQADAAVRLS--CDVHPDVLHNASRSGMNDHPDSGVSVGLTG
: ::
MAV_1135|M.avium_104 SGATDLNEVYSGTETAQERLSSYAQIAGGHIVAERAIRQLQLPMSADDLL
MMAR_4516|M.marinum_M SGQTDVNDVYWGGQAAQDLLSSYAEIAGGREVAQRAISQLQLPISPEALV
Mflv_4771|M.gilvum_PYR-GCK SSSSSVSEIYQGNRFSQERVVSYAELLMGETLAQRTIDKLGLDMSASSLR
Mvan_1681|M.vanbaalenii_PYR-1 AAGSSLSDMYQGNRFSQERVVSYAELLKGETLAQRTIDKLGLDMTAGALR
MSMEG_5955|M.smegmatis_MC2_155 EG-STTAAAYQNEEVAIRRIRTYIPLLKSDVVTQRVIDKLGLPMTAKQLA
Mb3949c|M.bovis_AF2122/97 ETSTEFDTPIGAAAERAMRVLHTTHEPLQRPGRRRVLTIANQKGGVGKTT
Rv3918c|M.tuberculosis_H37Rv ETSTEFDTPIGAAAERAMRVLHTTHEPLQRPGRRRVLTIANQKGGVGKTT
TH_3875|M.thermoresistible__bu RPPRPIPEPP----------------PKSTHGPAKVIAMCNQKGGVGKTT
MUL_3237|M.ulcerans_Agy99 RPPRAIPDPK----------------PLSSHGPAKVVAMCNQKGGVGKTT
:.:
MAV_1135|M.avium_104 SQTQVK-YTPKSVMFTISVKDTDPARAAALAGAMANQFSALLPTIAPNTG
MMAR_4516|M.marinum_M QQTQVK-YTPKSMLFTIAVSDTDPKRAALLAGGMADSFATLVGTLG--SA
Mflv_4771|M.gilvum_PYR-GCK ENISAS-AKPDTVLIDVAVRDPSPVRARDIANTLSDEFVAMVRELETPDG
Mvan_1681|M.vanbaalenii_PYR-1 ANVSAS-AKPDTVLIDVKVLDPSPVRARDIANTLSDEFVAMIRELETPED
MSMEG_5955|M.smegmatis_MC2_155 EELSATNVPPKTSLIDIRISDSSPQRAELIANTVAREFVAYTAAIETATG
Mb3949c|M.bovis_AF2122/97 TAVNIA-AALAVQGLKTLVIDLDPQGNASTALGITDRQSGTPSSYEMLIG
Rv3918c|M.tuberculosis_H37Rv TAVNIA-AALAVQGLKTLVIDLDPQGNASTALGITDRQSGTPSSYEMLIG
TH_3875|M.thermoresistible__bu STINLG-ASLAEYGRRVLLVDLDPQGALSAGLGVPHYDLDHTVYNLLVEP
MUL_3237|M.ulcerans_Agy99 STINLG-AALAEYDRRVLLVDMDPQGALSAGLGVAHYELEKTIHNVLVEP
. : * .* . :.
MAV_1135|M.avium_104 PNTVGAQATAGPRPEVAETTPAPGQPPEAPAAVGPTGKPWPLARATMVEP
MMAR_4516|M.marinum_M PRALGAE-------------PQQQAPPTAP-----------MARVTVVKR
Mflv_4771|M.gilvum_PYR-GCK GATPDAR-------------------------------------VVVEQR
Mvan_1681|M.vanbaalenii_PYR-1 GSRPDSR-------------------------------------VVVEQR
MSMEG_5955|M.smegmatis_MC2_155 EDDQKVQ-------------------------------------TTMVSD
Mb3949c|M.bovis_AF2122/97 EVSLHTA---------------------------------------LRRS
Rv3918c|M.tuberculosis_H37Rv EVSLHTA---------------------------------------LRRS
TH_3875|M.thermoresistible__bu RVSIDEV---------------------------------------LVST
MUL_3237|M.ulcerans_Agy99 RVSVDDV---------------------------------------LIHT
:
MAV_1135|M.avium_104 PRVPNVPVSPVPLRNMVIGFIAGLLLAIAVALTREAGDRTVRTRAKLEEL
MMAR_4516|M.marinum_M AEVPVSPSRPLPKRNLVMGLAAGLLLGIAVALAREASDRTVHSRRQLDQL
Mflv_4771|M.gilvum_PYR-GCK ATIPEHPVVPNTTRNIAMGLALGVLLGVAIAVVRDLLDNTVKDRETLEGI
Mvan_1681|M.vanbaalenii_PYR-1 ASLPVTPVVPKTGRNIMFGVALGLLLGFGVAIVRDLLDNTVKDRKTLEEI
MSMEG_5955|M.smegmatis_MC2_155 ATPARRDPVERALLYLLAALAALLLGGAAVWLR--------ASREQLDAD
Mb3949c|M.bovis_AF2122/97 PHSERLFCIPATIDLAGAEIELVSMVARENRLRTALAALDNFDFDYVFVD
Rv3918c|M.tuberculosis_H37Rv PHSERLFCIPATIDLAGAEIELVSMVARENRLRTALAALDNFDFDYVFVD
TH_3875|M.thermoresistible__bu -RVRNLDLVPSNIDLSAAEIQLVTEVGREQALARALHPVLDR-YDYVLID
MUL_3237|M.ulcerans_Agy99 -RVKNLDLVPSNIDLSAAEIQLVNEVGREQTLGRALYPVLDR-YDYVLVD
. . : :
MAV_1135|M.avium_104 SGLPTLAELP-----GRRGGTPRFGTDTAFDDAVRGMRT-RLLRAMGPDA
MMAR_4516|M.marinum_M SGLPTLAELP-----GRRGGVPQFGNDAAIDDAVRGLRT-RLLRAMGPQA
Mflv_4771|M.gilvum_PYR-GCK TGAGIVGSVPLDKERRKQAAVAFDRDNSGIAEAFRKLRTNLQFLAVDNPP
Mvan_1681|M.vanbaalenii_PYR-1 AGTGVVGAVPLDKERRKQAAISFDSDNSGISEAFRKLRTNLQFLAVDHPP
MSMEG_5955|M.smegmatis_MC2_155 SDDPVG--------RAPKAAQTVEGS------------------------
Mb3949c|M.bovis_AF2122/97 CPPSLGLLTINALVAAPEVMIPIQCEYYALEGVSQLMRNIEMVKAHLNPQ
Rv3918c|M.tuberculosis_H37Rv CPPSLGLLTINALVAAPEVMIPIQCEYYALEGVSQLMRNIEMVKAHLNPQ
TH_3875|M.thermoresistible__bu CQPSLGLLTVNGLACSDGVIIPTECEYFSLRGLALLTDTVDKVRDRLNPK
MUL_3237|M.ulcerans_Agy99 CQPSLGLLTVNGLACADGVVIPTECEYFSLRGLALLTDTVEKVRDRLNPR
.
MAV_1135|M.avium_104 RQVLVTGPFGGEGTTTTAMNLALALAEMGEDALLVEGDSRRHVIAGLLRV
MMAR_4516|M.marinum_M RRLVVAAPFAGEGTTTTALNLSLSLAELGEDVLLVEGDTRRPVIAGLLKV
Mflv_4771|M.gilvum_PYR-GCK RVIVVTSSMPSEGKSTTAINIALALAEGEHSVVLVDGDMRRPSLHKYLGL
Mvan_1681|M.vanbaalenii_PYR-1 RVIVVTSSMPGEGKSTTAINIALALAEAGRNVALIDGDLRRPTLHKYLDL
MSMEG_5955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3949c|M.bovis_AF2122/97 LEVTTVILTMYDGRTKLADQVADEVRQYFGSKVLRTVIPRSVKVSEAPGY
Rv3918c|M.tuberculosis_H37Rv LEVTTVILTMYDGRTKLADQVADEVRQYFGSKVLRTVIPRSVKVSEAPGY
TH_3875|M.thermoresistible__bu LEISGILVTRYDPRTVNSREVMARVVERFDDLVFDTVITRTVRFPETSVA
MUL_3237|M.ulcerans_Agy99 LDITGILLTRYDPRTVNSREVMARVVERFGDLVFDTVITRTVRFPETSVA
MAV_1135|M.avium_104 ESGEGLASALANPAAAAEVVKPTPISRLFILASRSARRESLPPSAYLPEV
MMAR_4516|M.marinum_M ESREGLANALANPEIALEVVKPTRISKLFILASRSVRRETASANAYLPEV
Mflv_4771|M.gilvum_PYR-GCK VGPVGFSTVLSGGTSLSEALQKTRFPGLTVLTSGAVPPN--PSELLGSQS
Mvan_1681|M.vanbaalenii_PYR-1 VGAVGFSTVLSGGVGLADALQKTRFPGLTVLTSGTIPPN--PSELLGSLA
MSMEG_5955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3949c|M.bovis_AF2122/97 SMTIIDYDPGSRGAMSYLDASRELAERDRPPSAKGRP-------------
Rv3918c|M.tuberculosis_H37Rv SMTIIDYDPGSRGAMSYLDASRELAERDRPPSAKGRP-------------
TH_3875|M.thermoresistible__bu GEPITTWAPKSTGAEAYRSLAREVIHRFGA--------------------
MUL_3237|M.ulcerans_Agy99 GEPITTWAPKSAGALAYRALAREFIDRFGV--------------------
MAV_1135|M.avium_104 VDRVVQELSSRFDRIVIDGPPVLATADTGLLSGAVPATVLVVRAKRTTAD
MMAR_4516|M.marinum_M IDSVLMDLSARFSRMVIDGPPVLATADTGLLAGAVQATVLVVRAGRTTVD
Mflv_4771|M.gilvum_PYR-GCK ARKLLSELRAEFDYVIVDSTPLLAVTDAAILGAGADGVLVMARFGQTKRD
Mvan_1681|M.vanbaalenii_PYR-1 ARKVVNELRAQFDYVVIDSTPLVAVTDAAILAAGADGVLIIARYGHTKRE
MSMEG_5955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3949c|M.bovis_AF2122/97 --------------------------------------------------
Rv3918c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3875|M.thermoresistible__bu --------------------------------------------------
MUL_3237|M.ulcerans_Agy99 --------------------------------------------------
MAV_1135|M.avium_104 ELRDALTALRAAGAHVVGTVLTDARQSLHIRAADRAYRSKVSRPA-----
MMAR_4516|M.marinum_M EVDDALSALRAAGANVVGTVLTDARISRHTSAAARIYRGKISGLS-----
Mflv_4771|M.gilvum_PYR-GCK QLAHAVGSLVDVGAPLLGAVFTMVPTRGSSSYSYSYSYYGSESAPQQARQ
Mvan_1681|M.vanbaalenii_PYR-1 QLAHAVGSLEGVGAPLLGAILTMMPTRGTGSYGYSYSYYGDDSTSSSSSR
MSMEG_5955|M.smegmatis_MC2_155 --------------------------------------------------
Mb3949c|M.bovis_AF2122/97 --------------------------------------------------
Rv3918c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3875|M.thermoresistible__bu --------------------------------------------------
MUL_3237|M.ulcerans_Agy99 --------------------------------------------------
MAV_1135|M.avium_104 -------------------------------------------------
MMAR_4516|M.marinum_M -------------------------------------------------
Mflv_4771|M.gilvum_PYR-GCK DVPVAPTKPAALDAAPSQTGAEPPDPDSSLPRADATPGASRRRRRQVSE
Mvan_1681|M.vanbaalenii_PYR-1 ---RMSAKLAALELPPPKSDHSLKPPQSIAESGPDIVQQTSAKRRRAAD
MSMEG_5955|M.smegmatis_MC2_155 -------------------------------------------------
Mb3949c|M.bovis_AF2122/97 -------------------------------------------------
Rv3918c|M.tuberculosis_H37Rv -------------------------------------------------
TH_3875|M.thermoresistible__bu -------------------------------------------------
MUL_3237|M.ulcerans_Agy99 -------------------------------------------------