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SAPWGPVAAGPSALVRSGQASTIEPFQREMTPPTPTPEAAHNPTMNVSRETSTEFDTPIGAAAERAMRVL HTTHEPLQRPGRRRVLTIANQKGGVGKTTTAVNIAAALAVQGLKTLVIDLDPQGNASTALGITDRQSGTP SSYEMLIGEVSLHTALRRSPHSERLFCIPATIDLAGAEIELVSMVARENRLRTALAALDNFDFDYVFVDC PPSLGLLTINALVAAPEVMIPIQCEYYALEGVSQLMRNIEMVKAHLNPQLEVTTVILTMYDGRTKLADQV ADEVRQYFGSKVLRTVIPRSVKVSEAPGYSMTIIDYDPGSRGAMSYLDASRELAERDRPPSAKGRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3918c | parA | - | 100% (347) | PROBABLE CHROMOSOME PARTITIONING PROTEIN PARA |
| M. tuberculosis H37Rv | Rv1708 | - | 2e-46 | 38.55% (262) | putative initiation inhibitor protein |
| M. tuberculosis H37Rv | Rv3213c | - | 3e-43 | 39.92% (263) | SOJ/PARA-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3949c | parA | 0.0 | 100.00% (347) | chromosome partitioning protein ParA |
| M. gilvum PYR-GCK | Mflv_0834 | - | 1e-127 | 79.25% (294) | cobyrinic acid a,c-diamide synthase |
| M. leprae Br4923 | MLBr_02707 | parA | 1e-146 | 77.65% (349) | putative cell division protein |
| M. abscessus ATCC 19977 | MAB_4950c | - | 1e-115 | 69.01% (313) | putative chromosome partitioning protein/ cobyrinic acid |
| M. marinum M | MMAR_5482 | parA | 1e-158 | 84.26% (343) | chromosome partitioning protein ParA |
| M. avium 104 | MAV_5307 | - | 1e-154 | 82.79% (337) | CobQ/CobB/MinD/ParA nucleotide binding domain-containing |
| M. smegmatis MC2 155 | MSMEG_6939 | - | 1e-128 | 77.12% (306) | Soj family protein |
| M. thermoresistible (build 8) | TH_2408 | parB | 1e-111 | 85.11% (235) | PROBABLE CHROMOSOME PARTITIONING PROTEIN PARA |
| M. ulcerans Agy99 | MUL_5071 | parA | 1e-155 | 89.29% (308) | chromosome partitioning protein ParA |
| M. vanbaalenii PYR-1 | Mvan_6072 | - | 1e-131 | 80.53% (303) | cobyrinic acid a,c-diamide synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0834|M.gilvum_PYR-GCK ----------------------------------------MSGSSDPGVA
Mvan_6072|M.vanbaalenii_PYR-1 ----------------------------------------MSASTDSGIP
MSMEG_6939|M.smegmatis_MC2_155 --------------------------------------MGSGQNKGQGVV
TH_2408|M.thermoresistible__bu --------------------------------------------------
Rv3918c|M.tuberculosis_H37Rv -----MSAPWG-----------------------PVAAGPSALVRSGQAS
Mb3949c|M.bovis_AF2122/97 -----MSAPWG-----------------------PVAAGPSALVRSGQAS
MMAR_5482|M.marinum_M MRLLRIPVPGAGASAAAKDDA-ESGGAAGVDKGSDAAAGTPAGVATGEAD
MUL_5071|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02707|M.leprae_Br4923 -----MSSLQG---------------------WVDTPALWSASLTDQSAL
MAV_5307|M.avium_104 -----MTSSGDWPVASSEAREGAATPAPDASSATHTPAAPIGPGAPSGTP
MAB_4950c|M.abscessus_ATCC_199 -------------------------------------------MSSDDVS
Mflv_0834|M.gilvum_PYR-GCK EESGTAPADSV----SRETEGSRETDVSRETWNP-QDVDTPIGAEAARAV
Mvan_6072|M.vanbaalenii_PYR-1 EA--IPPAD-----------------VSRETWNS-PEVDTPIGAEAERAV
MSMEG_6939|M.smegmatis_MC2_155 QKPNVSRET---------------WDSATSTWVTDAAMDTPIAAEAEQAT
TH_2408|M.thermoresistible__bu --------------------------------------------------
Rv3918c|M.tuberculosis_H37Rv T---IEPFQRE-MTPPTPTPEAAHNPTMNVSRETSTEFDTPIGAAAERAM
Mb3949c|M.bovis_AF2122/97 T---IEPFQRE-MTPPTPTPEAAHNPTMNVSRETSTEFDTPIGAAAERAM
MMAR_5482|M.marinum_M APEAVEATGPD-ADGVASAAESADNPTVNVSRETSSEFDTPIGAAAERAM
MUL_5071|M.ulcerans_Agy99 ----MEATGPD-ADGVASAAESADNPTVNVSRETSSEFDTPIGAAAERAM
MLBr_02707|M.leprae_Br4923 LSSEIQKTPPEPMFRQEAYYDAECVVEMNVSHETTNELDTPIGAAAERAM
MAV_5307|M.avium_104 GASAVASPAPTAATAPPSSAAAPAPPPANVSRETADEFDTPIGAAAERAM
MAB_4950c|M.abscessus_ATCC_199 RETGAASDG-------------------HRAPTEFVESETPIGAAAQRAT
Mflv_0834|M.gilvum_PYR-GCK RLMQAAVQGQLPRPSRQRVFTIANQKGGVGKTTTAVNIAAALALQGLRVL
Mvan_6072|M.vanbaalenii_PYR-1 RLMQAAVQGQLPRPKRQRVFTVANQKGGVGKTTTAVNIAAALALQGLRTL
MSMEG_6939|M.smegmatis_MC2_155 RVLHSSARRQLPRPERQRVFTIANQKGGVGKTTTAVNVAAALALQGLRTL
TH_2408|M.thermoresistible__bu -----------------------------------VNVAAALALQGLKTL
Rv3918c|M.tuberculosis_H37Rv RVLHTTHE-PLQRPGRRRVLTIANQKGGVGKTTTAVNIAAALAVQGLKTL
Mb3949c|M.bovis_AF2122/97 RVLHTTHE-PLQRPGRRRVLTIANQKGGVGKTTTAVNIAAALAVQGLKTL
MMAR_5482|M.marinum_M RVLHTTHD-PLKPPHQRRVFTIANQKGGVGKTTTAVNLAAALAIQGLKTL
MUL_5071|M.ulcerans_Agy99 RVLHTTHD-PLKPPHQRRVFTIANQKGGVGKTTTAVNLAAALAIQGLKTL
MLBr_02707|M.leprae_Br4923 RVLHTTYD-PLCRPCHRRLFTIANQKGGVGKTTTAVNLAAALALQGLKAL
MAV_5307|M.avium_104 RILHTTYP-PLRRPKHRRVFTVANQKGGVGKTTTAVNLAAALALQGLKTL
MAB_4950c|M.abscessus_ATCC_199 QLKQGSVR--LPKPAHRRMLTIANQKGGVGKTTTAVNLAAAMALQGLNVL
**:***:*:***..*
Mflv_0834|M.gilvum_PYR-GCK VIDLDPQGNASTALGIEHR-PGTPSSYEVLIGEIGVESALQRSPHNERLY
Mvan_6072|M.vanbaalenii_PYR-1 VIDLDPQGNASTALGIEHR-PGTPSSYEVLIGDISVEAALQRSPHSERLY
MSMEG_6939|M.smegmatis_MC2_155 VIDLDPQGNASTALSIEHR-PGTPSSYEVLIGEIPVEEALQQSPHNERLY
TH_2408|M.thermoresistible__bu VIDLDPQGNASTALGIEHR-PGTPSSYEVLIGEIELETALQRSPHNERLY
Rv3918c|M.tuberculosis_H37Rv VIDLDPQGNASTALGITDRQSGTPSSYEMLIGEVSLHTALRRSPHSERLF
Mb3949c|M.bovis_AF2122/97 VIDLDPQGNASTALGITDRQSGTPSSYEMLIGEVSLHTALRRSPHSERLF
MMAR_5482|M.marinum_M VIDLDPQGNASTALGITDRQSGTPSSYEVLIGEVSLREALRRSPHSDRLF
MUL_5071|M.ulcerans_Agy99 VIDLDPQGNASTALGITDRQSGTPSSYEVLIGDVSLREALRRSPRSDRLF
MLBr_02707|M.leprae_Br4923 VIDLDPQGNASTALGISNRQSRVFSSYDVLIGEVSLQTALRCSPYNERLF
MAV_5307|M.avium_104 VIDLDPQGNASTALGITDRQSGTPSSYEVLLGEVSVHDALRQSPHNERLF
MAB_4950c|M.abscessus_ATCC_199 VIDLDPQGNASTALGADHR-AGTPSSYEVLLGEIPIQDAIQSSPQSEHLF
**************. .* . . ***::*:*:: :. *:: ** .::*:
Mflv_0834|M.gilvum_PYR-GCK CIPATIDLAGAEIELVSMVAREGRLRTALAELKHHDFDYVFIDCPPSLGL
Mvan_6072|M.vanbaalenii_PYR-1 CIPATIDLAGAEIELVSMVAREGRLRTALGELKHYDFDYVFIDCPPSLGL
MSMEG_6939|M.smegmatis_MC2_155 CIPATIDLAGAEIELVSMVAREGRLRTALAELKNHNFDYVFIDCPPSLGL
TH_2408|M.thermoresistible__bu CVPATIDLAGAEIELVSMVAREGRLRGALAELKNYDFDYVFIDCPPSLGL
Rv3918c|M.tuberculosis_H37Rv CIPATIDLAGAEIELVSMVARENRLRTALAALDNFDFDYVFVDCPPSLGL
Mb3949c|M.bovis_AF2122/97 CIPATIDLAGAEIELVSMVARENRLRTALAALDNFDFDYVFVDCPPSLGL
MMAR_5482|M.marinum_M CVPATIDLAGAEIELVSMVARENRLRNALAELDQFDFDYVFVDCPPSLGL
MUL_5071|M.ulcerans_Agy99 CVPATIDLAGAEIELVSMVARENRLRNALAELDQFDFDYVFVDCPPSLGL
MLBr_02707|M.leprae_Br4923 CLPAAIDLAGAEIELVSMVARENRLRTALTELNDLDFDYVFIDCPPSLGL
MAV_5307|M.avium_104 CIPATIDLAGAEIELVSMVARENRLRTALADLDNLDFDCVFIDCPPSLGL
MAB_4950c|M.abscessus_ATCC_199 CVPATIDLAGAEIELVSMVAREGRLRSAIAGLPADAFDFVFIDCPPSLGL
*:**:*****************.*** *: * ** **:********
Mflv_0834|M.gilvum_PYR-GCK LTINALVAAPEVLIPIQCEYYALEGVGQLLRNIEMVKAHLNPELDVSTVV
Mvan_6072|M.vanbaalenii_PYR-1 LTINALVAAPEVLIPIQCEYYALEGVGQLLRNIEMVKAHLNPELEVTTVV
MSMEG_6939|M.smegmatis_MC2_155 LTINALVAAPEVLIPIQCEYYALEGVGQLLRNIEMVKAHLNPELSVSTVI
TH_2408|M.thermoresistible__bu LTINALVAAPEVLIPIQCEYYALEGVGQLLRNIQMVKAHLNPELEVTTVL
Rv3918c|M.tuberculosis_H37Rv LTINALVAAPEVMIPIQCEYYALEGVSQLMRNIEMVKAHLNPQLEVTTVI
Mb3949c|M.bovis_AF2122/97 LTINALVAAPEVMIPIQCEYYALEGVSQLMRNIEMVKAHLNPQLEVTTVI
MMAR_5482|M.marinum_M LTINALVAAPEVLIPIQCEYYALEGVSQLMRNIEMVKAHLNPDLEVTTVI
MUL_5071|M.ulcerans_Agy99 LTINALVAAPEVLIPIQCEYYALEGVSQLMRNIEMVKAHLNPDLEVTTVI
MLBr_02707|M.leprae_Br4923 LTINALVAAPEVIIPIQCEYYALEGVSQLMCNIEMVKAHLNPQLEVTTVI
MAV_5307|M.avium_104 LTINALVAAPEVMIPIQCEYYALEGVSQLMRNIEMVKAHLNPQLEVSTVV
MAB_4950c|M.abscessus_ATCC_199 LTVNALVAANEVLIPIQCEYYALEGVGQLLRNIELVQAHLNPALHVSTIL
**:****** **:*************.**: **::*:***** * *:*::
Mflv_0834|M.gilvum_PYR-GCK LTMHDGRTKLADQVANDVREHFGNKVLRTVIPRSVKVSEAPGYGMTIISY
Mvan_6072|M.vanbaalenii_PYR-1 LTMYDGRTKLADQVAMDVRAHFGDKVLRTVIPRSVKVSEAPGYGMTIIDY
MSMEG_6939|M.smegmatis_MC2_155 LTMYDGRTKLADQVAEDVREHFGDKVLRTVIPRSVKVSEAPGYGMTILNY
TH_2408|M.thermoresistible__bu LTMYDGRTKLADQVAADVRAHFGDKVLRTVIPRSVKVSEAPGYGMTILDY
Rv3918c|M.tuberculosis_H37Rv LTMYDGRTKLADQVADEVRQYFGSKVLRTVIPRSVKVSEAPGYSMTIIDY
Mb3949c|M.bovis_AF2122/97 LTMYDGRTKLADQVADEVRQYFGSKVLRTVIPRSVKVSEAPGYSMTIIDY
MMAR_5482|M.marinum_M LTMYDGRTKLADQVAEEVRSYFGDKVLRTVIPRSVKVSEAPGYSMTIIDY
MUL_5071|M.ulcerans_Agy99 LTMYDGRTKLADQVAEEVRSYFGDKALRTVIPRSVKVSEAPGYSMTIIDY
MLBr_02707|M.leprae_Br4923 LTMYDGRTKLADQVAEEVRRYFGTKVLQTVIPRSVKVSEAPGYSMTIIDY
MAV_5307|M.avium_104 LTMYDGRTKLADQVAEEVRRYFGSKVLRTVIPRSVKVSEAPGYSMTIIDY
MAB_4950c|M.abscessus_ATCC_199 LTMYDGRTKLADQVADEVRGHFGPKVLGSVIPRSVKVSEAPGYGTSVLEY
***:*********** :** :** *.* :**************. :::.*
Mflv_0834|M.gilvum_PYR-GCK DPGSRGAMSYLDASRELALRGGTAQDEGGRDR----------
Mvan_6072|M.vanbaalenii_PYR-1 DPGSRGAMSYLDASRELALRGG---DEGGGDR----------
MSMEG_6939|M.smegmatis_MC2_155 DPGSRGALSYLDASREIAERGAPPRQQ---------------
TH_2408|M.thermoresistible__bu DAGSRGAMSYLDASREIAERGLQQGRQAQQPGTGQPNSKDHA
Rv3918c|M.tuberculosis_H37Rv DPGSRGAMSYLDASRELAERDRPPSAKGRP------------
Mb3949c|M.bovis_AF2122/97 DPGSRGAMSYLDASRELAERDRPPSAKGRP------------
MMAR_5482|M.marinum_M DPGSRGAMSYLDASRELAQRDRPQTGKERA------------
MUL_5071|M.ulcerans_Agy99 DPGSRGAMSYLDASRELAQRDRPQTGKERA------------
MLBr_02707|M.leprae_Br4923 DPGSRGAMSYLDASRELAERDQPPSMKG--------------
MAV_5307|M.avium_104 DPGSRGAMSYLDASRELAERD---------------------
MAB_4950c|M.abscessus_ATCC_199 DPGSRGALSYLDAARELAQRPSSSASDPQ-------------
*.*****:*****:**:* *