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DFRTFVQTLAKRWKLVVGALLACLAGATAVTAFQTKVYQSSATIFISVSGQTDVNDVYWGGQAAQDLLSS YAEIAGGREVAQRAISQLQLPISPEALVQQTQVKYTPKSMLFTIAVSDTDPKRAALLAGGMADSFATLVG TLGSAPRALGAEPQQQAPPTAPMARVTVVKRAEVPVSPSRPLPKRNLVMGLAAGLLLGIAVALAREASDR TVHSRRQLDQLSGLPTLAELPGRRGGVPQFGNDAAIDDAVRGLRTRLLRAMGPQARRLVVAAPFAGEGTT TTALNLSLSLAELGEDVLLVEGDTRRPVIAGLLKVESREGLANALANPEIALEVVKPTRISKLFILASRS VRRETASANAYLPEVIDSVLMDLSARFSRMVIDGPPVLATADTGLLAGAVQATVLVVRAGRTTVDEVDDA LSALRAAGANVVGTVLTDARISRHTSAAARIYRGKISGLS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4516 | - | - | 100% (461) | hypothetical protein MMAR_4516 |
| M. marinum M | MMAR_2523 | - | 3e-05 | 27.57% (214) | Soj family ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1735 | - | 5e-05 | 27.93% (179) | putative initiation inhibitor protein |
| M. gilvum PYR-GCK | Mflv_4771 | - | 5e-57 | 31.98% (444) | lipopolysaccharide biosynthesis |
| M. tuberculosis H37Rv | Rv1708 | - | 5e-05 | 27.93% (179) | putative initiation inhibitor protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | MAV_1135 | - | 1e-165 | 64.26% (484) | chain length determinant protein |
| M. smegmatis MC2 155 | MSMEG_5954 | - | 6e-15 | 30.14% (209) | cell surface polysaccharide biosynthesis, putative |
| M. thermoresistible (build 8) | TH_3875 | - | 2e-06 | 30.73% (179) | PUTATIVE Cobyrinic acid a,c-diamide synthase |
| M. ulcerans Agy99 | MUL_3237 | - | 1e-05 | 27.57% (214) | Soj family ATPase |
| M. vanbaalenii PYR-1 | Mvan_1681 | - | 1e-59 | 31.08% (444) | lipopolysaccharide biosynthesis |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1735|M.bovis_AF2122/97 ---MPAGLPGQASVAVRLSCDVPPDARHHEPRPGMTDHPDTGNGIGLTGR
Rv1708|M.tuberculosis_H37Rv ---MPAGLPGQASVAVRLSCDVPPDARHHEPRPGMTDHPDTGNGIGLTGR
MUL_3237|M.ulcerans_Agy99 ---MPAGLPAQADAAVRLSCDVHPDVLHNASRSGMNDHPDSGVSVGLTGR
TH_3875|M.thermoresistible__bu ----------------------------------MTDDAVTAEVVGLTGR
MMAR_4516|M.marinum_M MDFRTFVQTLAKRWKLVVGALLACLAGATAVTAFQTKVYQSSATIFISVS
MAV_1135|M.avium_104 MDFRTFVRILGAHWKLALTALLACTVGAAFVTALQTKHYQSSATVLISFS
Mflv_4771|M.gilvum_PYR-GCK MNLQDFVKLLRSRWMTVCVTMVFAVMGAIAYTLLITPQYQASTRLFVSTS
Mvan_1681|M.vanbaalenii_PYR-1 MNLQDFVKLLRARWITLCVALIVAVLGAVAVSMLTTPLYQASTRLFVSTA
MSMEG_5954|M.smegmatis_MC2_155 ---MTYLRLLRIRWRWLVWGVLLALAVATVVLILQPPMYQSKATVLVRTP
: : :
Mb1735|M.bovis_AF2122/97 PPRAIPDPTPRSSHGPAKVIAMCNQKGG---VGKTTSTINLGAALGEYGR
Rv1708|M.tuberculosis_H37Rv PPRAIPDPAPRSSHGPAKVIAMCNQKGG---VGKTTSTINLGAALGEYGR
MUL_3237|M.ulcerans_Agy99 PPRAIPDPKPLSSHGPAKVVAMCNQKGG---VGKTTSTINLGAALAEYDR
TH_3875|M.thermoresistible__bu PPRPIPEPPPKSTHGPAKVIAMCNQKGG---VGKTTSTINLGASLAEYGR
MMAR_4516|M.marinum_M GQTDVNDVYWGGQAAQDLLSSYAEIAGGREVAQRAISQLQLPISPEALVQ
MAV_1135|M.avium_104 GATDLNEVYSGTETAQERLSSYAQIAGGHIVAERAIRQLQLPMSADDLLS
Mflv_4771|M.gilvum_PYR-GCK SSSSVSEIYQGNRFSQERVVSYAELLMGETLAQRTIDKLGLDMSASSLRE
Mvan_1681|M.vanbaalenii_PYR-1 AGSSLSDMYQGNRFSQERVVSYAELLKGETLAQRTIDKLGLDMTAGALRA
MSMEG_5954|M.smegmatis_MC2_155 GDVSR-VVDGGDTYARSRAATYAQLAKSSTVAERVIADLHLDIAPATLSS
. : .: . . :. : * :
Mb1735|M.bovis_AF2122/97 -------------RVLLVDMDP--QGALSAGLGVPHYELDKTIHN-----
Rv1708|M.tuberculosis_H37Rv -------------RVLLVDMDP--QGALSAGLGVPHYELDKTIHN-----
MUL_3237|M.ulcerans_Agy99 -------------RVLLVDMDP--QGALSAGLGVAHYELEKTIHN-----
TH_3875|M.thermoresistible__bu -------------RVLLVDLDP--QGALSAGLGVPHYDLDHTVYN-----
MMAR_4516|M.marinum_M QTQVKYTPKSMLFTIAVSDTDPKRAALLAGGMADSFATLVGTLG--SAPR
MAV_1135|M.avium_104 QTQVKYTPKSVMFTISVKDTDPARAAALAGAMANQFSALLPTIAPNTGPN
Mflv_4771|M.gilvum_PYR-GCK NISASAKPDTVLIDVAVRDPSPVRARDIANTLSDEFVAMVRELET-----
Mvan_1681|M.vanbaalenii_PYR-1 NVSASAKPDTVLIDVKVLDPSPVRARDIANTLSDEFVAMIRELET-----
MSMEG_5954|M.smegmatis_MC2_155 RINAENVPGTALITVTASAPSAGQAQQTATMFLSGYGATVRMLES-----
: .. : : . :
Mb1735|M.bovis_AF2122/97 ------------------------------------------VLVEPRVS
Rv1708|M.tuberculosis_H37Rv ------------------------------------------VLVEPRVS
MUL_3237|M.ulcerans_Agy99 ------------------------------------------VLVEPRVS
TH_3875|M.thermoresistible__bu ------------------------------------------LLVEPRVS
MMAR_4516|M.marinum_M ALGAE-------------PQQQAPPTAP-----------MARVTVVKRAE
MAV_1135|M.avium_104 TVGAQATAGPRPEVAETTPAPGQPPEAPAAVGPTGKPWPLARATMVEPPR
Mflv_4771|M.gilvum_PYR-GCK ------------------PDGGATPDAR--------------VVVEQRAT
Mvan_1681|M.vanbaalenii_PYR-1 ------------------PEDGSRPDSR--------------VVVEQRAS
MSMEG_5954|M.smegmatis_MC2_155 ----------------------------------------VPGSLVPRAE
:
Mb1735|M.bovis_AF2122/97 IDDVLIHSR-VKNMDLVPSNIDLSAAEIQLVNEVGREQTLARALYPVLD-
Rv1708|M.tuberculosis_H37Rv IDDVLIHSR-VKNMDLVPSNIDLSAAEIQLVNEVGREQTLARALYPVLD-
MUL_3237|M.ulcerans_Agy99 VDDVLIHTR-VKNLDLVPSNIDLSAAEIQLVNEVGREQTLGRALYPVLD-
TH_3875|M.thermoresistible__bu IDEVLVSTR-VRNLDLVPSNIDLSAAEIQLVTEVGREQALARALHPVLD-
MMAR_4516|M.marinum_M VPVSPSRPLPKRNLVMGLAAGLLLGIAVALAREASDRTVHSRRQLDQLSG
MAV_1135|M.avium_104 VPNVPVSPVPLRNMVIGFIAGLLLAIAVALTREAGDRTVRTRAKLEELSG
Mflv_4771|M.gilvum_PYR-GCK IPEHPVVPNTTRNIAMGLALGVLLGVAIAVVRDLLDNTVKDRETLEGITG
Mvan_1681|M.vanbaalenii_PYR-1 LPVTPVVPKTGRNIMFGVALGLLLGFGVAIVRDLLDNTVKDRKTLEEIAG
MSMEG_5954|M.smegmatis_MC2_155 LVVVDPPGMPSRMVASGVPLPLLL-FGVALTGLVAAATIVAVR-------
: : : * : :.
Mb1735|M.bovis_AF2122/97 -----------------------------------RYDYVLIDCQPSLGL
Rv1708|M.tuberculosis_H37Rv -----------------------------------RYDYVLIDCQPSLGL
MUL_3237|M.ulcerans_Agy99 -----------------------------------RYDYVLVDCQPSLGL
TH_3875|M.thermoresistible__bu -----------------------------------RYDYVLIDCQPSLGL
MMAR_4516|M.marinum_M LPTLAELPG----RRGGVPQFG-NDAAIDDAVRGLRT-RLLRAMGPQARR
MAV_1135|M.avium_104 LPTLAELPG----RRGGTPRFG-TDTAFDDAVRGMRT-RLLRAMGPDARQ
Mflv_4771|M.gilvum_PYR-GCK AGIVGSVPLDKERRKQAAVAFDRDNSGIAEAFRKLRTNLQFLAVDNPPRV
Mvan_1681|M.vanbaalenii_PYR-1 TGVVGAVPLDKERRKQAAISFDSDNSGISEAFRKLRTNLQFLAVDHPPRV
MSMEG_5954|M.smegmatis_MC2_155 -----------------------------------------SALHPYAET
Mb1735|M.bovis_AF2122/97 LTVNGLACTDG-------------------VIIPTECEFFSLRGLALLTD
Rv1708|M.tuberculosis_H37Rv LTVNGLACTDG-------------------VIIPTECEFFSLRGLALLTD
MUL_3237|M.ulcerans_Agy99 LTVNGLACADG-------------------VVIPTECEYFSLRGLALLTD
TH_3875|M.thermoresistible__bu LTVNGLACSDG-------------------VIIPTECEYFSLRGLALLTD
MMAR_4516|M.marinum_M LVVAAPFAGEGTTTTALNLSLSLAELGEDVLLVEGDTRRPVIAGLLKVES
MAV_1135|M.avium_104 VLVTGPFGGEGTTTTAMNLALALAEMGEDALLVEGDSRRHVIAGLLRVES
Mflv_4771|M.gilvum_PYR-GCK IVVTSSMPSEGKSTTAINIALALAEGEHSVVLVDGDMRRPSLHKYLGLVG
Mvan_1681|M.vanbaalenii_PYR-1 IVVTSSMPGEGKSTTAINIALALAEAGRNVALIDGDLRRPTLHKYLDLVG
MSMEG_5954|M.smegmatis_MC2_155 ETEPSGVKG-----------------------------------------
.
Mb1735|M.bovis_AF2122/97 TVDKVRDRLNPKLDISGILITRYDPRTVNS-------------------R
Rv1708|M.tuberculosis_H37Rv TVDKVRDRLNPKLDISGILITRYDPRTVNS-------------------R
MUL_3237|M.ulcerans_Agy99 TVEKVRDRLNPRLDITGILLTRYDPRTVNS-------------------R
TH_3875|M.thermoresistible__bu TVDKVRDRLNPKLEISGILVTRYDPRTVNS-------------------R
MMAR_4516|M.marinum_M REGLANALANPEIALEVVKPTRISKLFILASRSVRRETASANAYLPEVID
MAV_1135|M.avium_104 GEGLASALANPAAAAEVVKPTPISRLFILASRSARRESLPPSAYLPEVVD
Mflv_4771|M.gilvum_PYR-GCK PVGFSTVLSGGTSLSEALQKTRFPGLTVLTSGAVPPN--PSELLGSQSAR
Mvan_1681|M.vanbaalenii_PYR-1 AVGFSTVLSGGVGLADALQKTRFPGLTVLTSGTIPPN--PSELLGSLAAR
MSMEG_5954|M.smegmatis_MC2_155 --------------------------------------------------
Mb1735|M.bovis_AF2122/97 EVMARVVERFGDLVFDT---VITRTVRFPETSVAGEPITTWAPKSAG---
Rv1708|M.tuberculosis_H37Rv EVMARVVERFGDLVFDT---VITRTVRFPETSVAGEPITTWAPKSAG---
MUL_3237|M.ulcerans_Agy99 EVMARVVERFGDLVFDT---VITRTVRFPETSVAGEPITTWAPKSAG---
TH_3875|M.thermoresistible__bu EVMARVVERFDDLVFDT---VITRTVRFPETSVAGEPITTWAPKSTG---
MMAR_4516|M.marinum_M SVLMDLSARFSRMVIDGPPVLATADTGLLAGAVQATVLVVRAGRTTVDEV
MAV_1135|M.avium_104 RVVQELSSRFDRIVIDGPPVLATADTGLLSGAVPATVLVVRAKRTTADEL
Mflv_4771|M.gilvum_PYR-GCK KLLSELRAEFDYVIVDSTPLLAVTDAAILGAGADGVLVMARFGQTKRDQL
Mvan_1681|M.vanbaalenii_PYR-1 KVVNELRAQFDYVVIDSTPLVAVTDAAILAAGADGVLIIARYGHTKREQL
MSMEG_5954|M.smegmatis_MC2_155 --------------------------------------------------
Mb1735|M.bovis_AF2122/97 ALAYRALARELIDRFGM---------------------------------
Rv1708|M.tuberculosis_H37Rv ALAYRALARELIDRFGM---------------------------------
MUL_3237|M.ulcerans_Agy99 ALAYRALAREFIDRFGV---------------------------------
TH_3875|M.thermoresistible__bu AEAYRSLAREVIHRFGA---------------------------------
MMAR_4516|M.marinum_M DDALSALRAAGANVVGTVLTDARIS-RHTSAAARIYRGKISGLS------
MAV_1135|M.avium_104 RDALTALRAAGAHVVGTVLTDARQS-LHIRAADRAYRSKVSRPA------
Mflv_4771|M.gilvum_PYR-GCK AHAVGSLVDVGAPLLGAVFTMVPTRGSSSYSYSYSYYGSESAPQQARQDV
Mvan_1681|M.vanbaalenii_PYR-1 AHAVGSLEGVGAPLLGAILTMMPTRGTGSYGYSYSYYGDDSTSSSSSR--
MSMEG_5954|M.smegmatis_MC2_155 --------------------------------------------------
Mb1735|M.bovis_AF2122/97 -----------------------------------------------
Rv1708|M.tuberculosis_H37Rv -----------------------------------------------
MUL_3237|M.ulcerans_Agy99 -----------------------------------------------
TH_3875|M.thermoresistible__bu -----------------------------------------------
MMAR_4516|M.marinum_M -----------------------------------------------
MAV_1135|M.avium_104 -----------------------------------------------
Mflv_4771|M.gilvum_PYR-GCK PVAPTKPAALDAAPSQTGAEPPDPDSSLPRADATPGASRRRRRQVSE
Mvan_1681|M.vanbaalenii_PYR-1 -RMSAKLAALELPPPKSDHSLKPPQSIAESGPDIVQQTSAKRRRAAD
MSMEG_5954|M.smegmatis_MC2_155 -----------------------------------------------