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M. smegmatis MC2 155 MSMEG_5955 (-)

annotation: protein-tyrosine kinase, putative
coordinates: 6015525 - 6016190
length: 221

LNLKSFVAAAQRFWSTYLLVAGLVLIVGAAAIMMLPVTYVSSARLMVSIEGSTTAAAYQNEEVAIRRIRT
YIPLLKSDVVTQRVIDKLGLPMTAKQLAEELSATNVPPKTSLIDIRISDSSPQRAELIANTVAREFVAYT
AAIETATGEDDQKVQTTMVSDATPARRDPVERALLYLLAALAALLLGGAAVWLRASREQLDADSDDPVGR
APKAAQTVEGS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5955--100% (221)protein-tyrosine kinase, putative
M. smegmatis MC2 155MSMEG_5954-1e-0926.53% (196) cell surface polysaccharide biosynthesis, putative

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_4771-1e-2133.33% (192) lipopolysaccharide biosynthesis
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4516-9e-1228.70% (230) hypothetical protein MMAR_4516
M. avium 104MAV_1135-1e-1432.22% (180) chain length determinant protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_1681-1e-2242.24% (161) lipopolysaccharide biosynthesis

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4771|M.gilvum_PYR-GCK          MNLQDFVKLLRSRWMTVCVTMVFAVMGAIAYTLLITPQYQASTRLFVSTS
Mvan_1681|M.vanbaalenii_PYR-1       MNLQDFVKLLRARWITLCVALIVAVLGAVAVSMLTTPLYQASTRLFVSTA
MSMEG_5955|M.smegmatis_MC2_155      MNLKSFVAAAQRFWSTYLLVAGLVLIVGAAAIMMLPVTYVSSARLMVSIE
MMAR_4516|M.marinum_M               MDFRTFVQTLAKRWKLVVGALLACLAGATAVTAFQTKVYQSSATIFISVS
MAV_1135|M.avium_104                MDFRTFVRILGAHWKLALTALLACTVGAAFVTALQTKHYQSSATVLISFS
                                    *::: **      *     .       .     : .  * :*: :::*  

Mflv_4771|M.gilvum_PYR-GCK          SSSSVSEIYQGNRFSQERVVSYAELLMGETLAQRTIDKLGLDMSASSLRE
Mvan_1681|M.vanbaalenii_PYR-1       AGSSLSDMYQGNRFSQERVVSYAELLKGETLAQRTIDKLGLDMTAGALRA
MSMEG_5955|M.smegmatis_MC2_155      G-STTAAAYQNEEVAIRRIRTYIPLLKSDVVTQRVIDKLGLPMTAKQLAE
MMAR_4516|M.marinum_M               GQTDVNDVYWGGQAAQDLLSSYAEIAGGREVAQRAISQLQLPISPEALVQ
MAV_1135|M.avium_104                GATDLNEVYSGTETAQERLSSYAQIAGGHIVAERAIRQLQLPMSADDLLS
                                    . :     * . . :   : :*  :  .  :::*.* :* * ::.  *  

Mflv_4771|M.gilvum_PYR-GCK          NISAS-AKPDTVLIDVAVRDPSPVRARDIANTLSDEFVAMVRELETPDGG
Mvan_1681|M.vanbaalenii_PYR-1       NVSAS-AKPDTVLIDVKVLDPSPVRARDIANTLSDEFVAMIRELETPEDG
MSMEG_5955|M.smegmatis_MC2_155      ELSATNVPPKTSLIDIRISDSSPQRAELIANTVAREFVAYTAAIETATGE
MMAR_4516|M.marinum_M               QTQVK-YTPKSMLFTIAVSDTDPKRAALLAGGMADSFATLVGTLG--SAP
MAV_1135|M.avium_104                QTQVK-YTPKSVMFTISVKDTDPARAAALAGAMANQFSALLPTIAPNTGP
                                    : ...   *.: :: : : *..* **  :*. :: .* :    :      

Mflv_4771|M.gilvum_PYR-GCK          ATPDAR-------------------------------------VVVEQRA
Mvan_1681|M.vanbaalenii_PYR-1       SRPDSR-------------------------------------VVVEQRA
MSMEG_5955|M.smegmatis_MC2_155      DDQKVQ-------------------------------------TTMVSDA
MMAR_4516|M.marinum_M               RALGAE-------------PQQQAPPTAP-----------MARVTVVKRA
MAV_1135|M.avium_104                NTVGAQATAGPRPEVAETTPAPGQPPEAPAAVGPTGKPWPLARATMVEPP
                                         .                                     ..: . .

Mflv_4771|M.gilvum_PYR-GCK          TIPEHPVVPNTTRNIAMGLALGVLLGVAIAVVRDLLDNTVKDRETLEGIT
Mvan_1681|M.vanbaalenii_PYR-1       SLPVTPVVPKTGRNIMFGVALGLLLGFGVAIVRDLLDNTVKDRKTLEEIA
MSMEG_5955|M.smegmatis_MC2_155      TPARRDPVERALLYLLAALAALLLGGAAVWLR--------ASREQLDADS
MMAR_4516|M.marinum_M               EVPVSPSRPLPKRNLVMGLAAGLLLGIAVALAREASDRTVHSRRQLDQLS
MAV_1135|M.avium_104                RVPNVPVSPVPLRNMVIGFIAGLLLAIAVALTREAGDRTVRTRAKLEELS
                                      .       .   :  ..   :* . .: :           *  *:  :

Mflv_4771|M.gilvum_PYR-GCK          GAGIVGSVPLDKERRKQAAVAFDRDNSGIAEAFRKLRTNLQFLAVDNPPR
Mvan_1681|M.vanbaalenii_PYR-1       GTGVVGAVPLDKERRKQAAISFDSDNSGISEAFRKLRTNLQFLAVDHPPR
MSMEG_5955|M.smegmatis_MC2_155      DDPVG--------RAPKAAQTVEGS-------------------------
MMAR_4516|M.marinum_M               GLPTLAELPGRRGGVPQFGNDAAIDDAVRGLRTRLLR------AMGPQAR
MAV_1135|M.avium_104                GLPTLAELPGRRGGTPRFGTDTAFDDAVRGMRTRLLR------AMGPDAR
                                    .               : .     .                         

Mflv_4771|M.gilvum_PYR-GCK          VIVVTSSMPSEGKSTTAINIALALAEGEHSVVLVDGDMRRPSLHKYLGLV
Mvan_1681|M.vanbaalenii_PYR-1       VIVVTSSMPGEGKSTTAINIALALAEAGRNVALIDGDLRRPTLHKYLDLV
MSMEG_5955|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_4516|M.marinum_M               RLVVAAPFAGEGTTTTALNLSLSLAELGEDVLLVEGDTRRPVIAGLLKVE
MAV_1135|M.avium_104                QVLVTGPFGGEGTTTTAMNLALALAEMGEDALLVEGDSRRHVIAGLLRVE
                                                                                      

Mflv_4771|M.gilvum_PYR-GCK          GPVGFSTVLSGGTSLSEALQKTRFPGLTVLTSGAVPPN--PSELLGSQSA
Mvan_1681|M.vanbaalenii_PYR-1       GAVGFSTVLSGGVGLADALQKTRFPGLTVLTSGTIPPN--PSELLGSLAA
MSMEG_5955|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_4516|M.marinum_M               SREGLANALANPEIALEVVKPTRISKLFILASRSVRRETASANAYLPEVI
MAV_1135|M.avium_104                SGEGLASALANPAAAAEVVKPTPISRLFILASRSARRESLPPSAYLPEVV
                                                                                      

Mflv_4771|M.gilvum_PYR-GCK          RKLLSELRAEFDYVIVDSTPLLAVTDAAILGAGADGVLVMARFGQTKRDQ
Mvan_1681|M.vanbaalenii_PYR-1       RKVVNELRAQFDYVVIDSTPLVAVTDAAILAAGADGVLIIARYGHTKREQ
MSMEG_5955|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_4516|M.marinum_M               DSVLMDLSARFSRMVIDGPPVLATADTGLLAGAVQATVLVVRAGRTTVDE
MAV_1135|M.avium_104                DRVVQELSSRFDRIVIDGPPVLATADTGLLSGAVPATVLVVRAKRTTADE
                                                                                      

Mflv_4771|M.gilvum_PYR-GCK          LAHAVGSLVDVGAPLLGAVFTMVPTRGSSSYSYSYSYYGSESAPQQARQD
Mvan_1681|M.vanbaalenii_PYR-1       LAHAVGSLEGVGAPLLGAILTMMPTRGTGSYGYSYSYYGDDSTSSSSSR-
MSMEG_5955|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_4516|M.marinum_M               VDDALSALRAAGANVVGTVLTDARISRHTSAAARIYRGKISGLS------
MAV_1135|M.avium_104                LRDALTALRAAGAHVVGTVLTDARQSLHIRAADRAYRSKVSRPA------
                                                                                      

Mflv_4771|M.gilvum_PYR-GCK          VPVAPTKPAALDAAPSQTGAEPPDPDSSLPRADATPGASRRRRRQVSE
Mvan_1681|M.vanbaalenii_PYR-1       --RMSAKLAALELPPPKSDHSLKPPQSIAESGPDIVQQTSAKRRRAAD
MSMEG_5955|M.smegmatis_MC2_155      ------------------------------------------------
MMAR_4516|M.marinum_M               ------------------------------------------------
MAV_1135|M.avium_104                ------------------------------------------------