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MLLEFDADQRLWQSTVRDAVTKQCPPSLVRSVAEEGVDPSPLWKSYVDQGWTELNDPESTVELAIVLEEL GHATDPTPFLATMSQFAPLVGEHFDPHQSGTAVYGGVCAYRDADGWVLDGTARHVLDGDRVDRLAVVTDA GVFITAANQVSARRTAVFDPVLHVADLSFAEVRVPDSARLSVDPERAHHVALTGMAITMVGACQRILDLV LEHVKSRQQFGVPIGSFQAVQHKVADMHVAVQRARALAYFAALTIAADDPRRRLAAAMAKASAGECQSLA FRHGLQLHGAMGFTWENDLQFALKRAKAGELMLGGAAEHRARIAEEYRAADF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0934 | - | - | 100% (332) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1838 | - | 2e-36 | 32.07% (368) | acyl-CoA dehydrogenase protein |
| M. avium 104 | MAV_1631 | - | 3e-33 | 32.65% (340) | putative acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3594 | fadE33 | 1e-30 | 32.42% (330) | acyl-CoA dehydrogenase FADE33 |
| M. gilvum PYR-GCK | Mflv_2491 | - | 1e-149 | 78.90% (327) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3564 | fadE33 | 1e-30 | 32.42% (330) | acyl-CoA dehydrogenase FADE33 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 2e-12 | 26.20% (229) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0594c | - | 3e-33 | 30.61% (330) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_4719 | - | 1e-166 | 86.75% (332) | acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4806 | - | 1e-143 | 74.70% (328) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3599 | - | 1e-155 | 78.96% (328) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_0319 | - | 1e-163 | 85.84% (332) | acyl-CoA dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4163 | - | 1e-145 | 77.48% (333) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3594|M.bovis_AF2122/97 ----------------MTPPEERQMLRETVASLVAKHAGPAAVRAAMASD
Rv3564|M.tuberculosis_H37Rv ----------------MTPPEERQMLRETVASLVAKHAGPAAVRAAMASD
MMAR_4719|M.marinum_M --------------MLLEFDADQRLWQATVRDVVTKQCPPSLVRSVAEN-
MUL_0319|M.ulcerans_Agy99 MLFSPVSARREAVRMLLEFDADQRLWQATVRDVVTKQCPPSLVRSVAEN-
MAV_0934|M.avium_104 --------------MLLEFDADQRLWQSTVRDAVTKQCPPSLVRSVAEE-
MSMEG_4806|M.smegmatis_MC2_155 --------------MLLEFDADQRLWQETVRDAVTKQCPATLVREVAEQ-
TH_3599|M.thermoresistible__bu --------------MLLEFDADQRLWQETVRDAVAKQCPASLIRSIVED-
Mflv_2491|M.gilvum_PYR-GCK --------------MLLEFDADQRLWQETVRDAVSKQCPASLIRGIAEN-
Mvan_4163|M.vanbaalenii_PYR-1 --------------MLLEFDADQKLWQETVRDAVSKQCPASLIRDIAEN-
MAB_0594c|M.abscessus_ATCC_199 --------------MKFDLDTQQRDFAASIDAALSVADVPAAARAWAAG-
MLBr_00737|M.leprae_Br4923 ----MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRA-
: ::. :: .
Mb3594|M.bovis_AF2122/97 RGYDESLWRLLCEQVGAAALVIPEELGGAGGELADAAIVVQELGRALVPS
Rv3564|M.tuberculosis_H37Rv RGYDESLWRLLCEQVGAAALVIPEELGGAGGELADAAIVVQELGRALVPS
MMAR_4719|M.marinum_M -GADSDPLWKVYVDLGWTELNDPASA-------VELAIVLEELGHATDPT
MUL_0319|M.ulcerans_Agy99 -GADSDPLWKVYVDLGWTELNDPASA-------VELAIVLEELGHATDPT
MAV_0934|M.avium_104 -GVDPSPLWKSYVDQGWTELNDPEST-------VELAIVLEELGHATDPT
MSMEG_4806|M.smegmatis_MC2_155 -GVDPAPLWKNYIEQGWTELTEPENA-------VELAIVLEELGRATDLT
TH_3599|M.thermoresistible__bu -GVDPGPLWKSFVDQGWTELTDPENA-------VELAIVVEELGRATDPT
Mflv_2491|M.gilvum_PYR-GCK -GVDPAPLWKSYLDAGWTELTDPENA-------VELAIVLEELGRATDPT
Mvan_4163|M.vanbaalenii_PYR-1 -GADATPLWNSYLDAGWTELTDPENA-------VELAIVLEELGRATDPT
MAB_0594c|M.abscessus_ATCC_199 NHGPGLAVWSTLAELGVTALAVSEKYDGIGAHPVDLVVALEGLGKWAVPG
MLBr_00737|M.leprae_Br4923 --RFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASA
* : . . . :.:: :.:
Mb3594|M.bovis_AF2122/97 ------------------------PLLGTTLAELALLAAAKPDAQALTEL
Rv3564|M.tuberculosis_H37Rv ------------------------PLLGTTLAELALLAAAKPDAQALTEL
MMAR_4719|M.marinum_M ------------------------PFLATMSQFAPLAAGCFDPHQSGTAV
MUL_0319|M.ulcerans_Agy99 ------------------------PFLATMSQFAPLAAGCFDPHQSGTAV
MAV_0934|M.avium_104 ------------------------PFLATMSQFAPLVGEHFDPHQSGTAV
MSMEG_4806|M.smegmatis_MC2_155 ------------------------PYLATMTQFAPLAGDRFDAASAGAAV
TH_3599|M.thermoresistible__bu ------------------------PFLATMTQFAPLVGERFDPHRAGAAV
Mflv_2491|M.gilvum_PYR-GCK ------------------------PFLATLTQFAPLVGDRFDSGGSGTAV
Mvan_4163|M.vanbaalenii_PYR-1 ------------------------PFLATLTQFAPLVGDRYDSSVAGTAV
MAB_0594c|M.abscessus_ATCC_199 ------------------------PVVESVAVAPVLLSSHEDGAEPSTRL
MLBr_00737|M.leprae_Br4923 SLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDA
: : : . . :
Mb3594|M.bovis_AF2122/97 AQG-SAIG------ALVLDPDYVVNGDIADIVVAATSGQ---------LT
Rv3564|M.tuberculosis_H37Rv AQG-SAIG------ALVLDPDYVVNGDIADIVVAATSGQ---------LT
MMAR_4719|M.marinum_M YNG-ITVRRDAQGWLLDGTARHVLEGDRADRLAVVTDAG---------VF
MUL_0319|M.ulcerans_Agy99 YNG-ITVRRDAQGWLLDGTARHVLERDRADRLAVVTDAG---------VF
MAV_0934|M.avium_104 YGG-VCAYRDADGWVLDGTARHVLDGDRVDRLAVVTDAG---------VF
MSMEG_4806|M.smegmatis_MC2_155 YGG-VTARRDETGWVLSGTGRHVLDGDRAETLAVVTEAG---------VF
TH_3599|M.thermoresistible__bu YGG-ISAHRDDTGWILDGTARHVLDADRAEQLAVVTSAG---------VF
Mflv_2491|M.gilvum_PYR-GCK YSG-ISAIRDAEGWVLTGTDRFVLDGDRADRLAVVTPAG---------VF
Mvan_4163|M.vanbaalenii_PYR-1 YSG-VTANRDAQGWVLSGTDRFVLDGDRADRLAVVTPAG---------VF
MAB_0594c|M.abscessus_ATCC_199 ASG-ELIAT----VAAPPIAPRALDADIAGLVLIADDIG---------IR
MLBr_00737|M.leprae_Br4923 ASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAF
: .
Mb3594|M.bovis_AF2122/97 RWTRFS------AQPVATMDPTRRLARLQSE-----ETEPLCPDPG----
Rv3564|M.tuberculosis_H37Rv RWTRFS------AQPVATMDPTRRLARLQSE-----ETEPLCPDPG----
MMAR_4719|M.marinum_M IVAASQ----VSARRESVFDPVLHVADLSFREVRVPENARVGVDAE----
MUL_0319|M.ulcerans_Agy99 IVAASQ----VSARRESVFDPVLHVADLSFREVRVPENARVGVDAE----
MAV_0934|M.avium_104 ITAANQ----VSARRTAVFDPVLHVADLSFAEVRVPDSARLSVDPE----
MSMEG_4806|M.smegmatis_MC2_155 LVDAGT----AAIRRSPVFDPVLHVAEVSFDGVAVADTDRVPVDIE----
TH_3599|M.thermoresistible__bu LVDAGV----ATVRRSQAFDPVLHITDVSFTGVQVPDTRRLATDPE----
Mflv_2491|M.gilvum_PYR-GCK VVEAGA----VTTRRVDVFDPVLHVAEVSFPGVHVAESDRLAVDTE----
Mvan_4163|M.vanbaalenii_PYR-1 CVDPRADSANVTTRRVDVFDPVLHVAEVSFAGTQVSDSDRLLVDTE----
MAB_0594c|M.abscessus_ATCC_199 EAQAGA--------QHESIDATRRVFDVQPK------EAGISLDTS----
MLBr_00737|M.leprae_Br4923 IVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKT
: :
Mb3594|M.bovis_AF2122/97 --IADTAAIL-LAAEQIGAAERCLQLTVEYAKSRVQFGRPIGSFQALKHR
Rv3564|M.tuberculosis_H37Rv --IADTAAIL-LAAEQIGAAERCLQLTVEYAKSRVQFGRPIGSFQALKHR
MMAR_4719|M.marinum_M --RARHIALTGMAITMVGACQRILDLVLEHVRSRHQFGVPIGSFQAVQHK
MUL_0319|M.ulcerans_Agy99 --RARHIALTGMAITMVGACQRILDLVLEHVRSRHQFGVPIGSFQAVQHK
MAV_0934|M.avium_104 --RAHHVALTGMAITMVGACQRILDLVLEHVKSRQQFGVPIGSFQAVQHK
MSMEG_4806|M.smegmatis_MC2_155 --KAHHLALTGMAVHTVGACRRVLDLVLEHAKQRQQFGVPIGSLQAVQHK
TH_3599|M.thermoresistible__bu --KARHVALTGMAMTMVGACQRVLDLALEHVKQRHQFGVPIGSFQAIQHK
Mflv_2491|M.gilvum_PYR-GCK --RAHHVALMGMAITTVGACQRILDLVLEHAKSRQQFGVAIGTFQAVQHK
Mvan_4163|M.vanbaalenii_PYR-1 --RARHVALMGMAVTMVGACQRILDLVLEHAKSRQQFGVAIGTFQAVQHK
MAB_0594c|M.abscessus_ATCC_199 --RAIDFGVLAISAQLIGAGQALLDRAVAYAKQRSQFGRPIGSYQAVKHK
MLBr_00737|M.leprae_Br4923 ALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFM
: :. :* . *: .: :.:.* *** .*.: *:::.
Mb3594|M.bovis_AF2122/97 MADLYVTIAAARAVVADACHAPTPTN------AATARLAASEALSTAAAE
Rv3564|M.tuberculosis_H37Rv MADLYVTIAAARAVVADACHAPTPTN------AATARLAASEALSTAAAE
MMAR_4719|M.marinum_M AADMHVAVQRARALAYFAALTISADDPRRRLAAAMAKASAGECQSLVFRH
MUL_0319|M.ulcerans_Agy99 AADMHVAVQRARALAYFAALTFSADDPRRRLAAAMAKASAGECQSLVFLH
MAV_0934|M.avium_104 VADMHVAVQRARALAYFAALTIAADDPRRRLAAAMAKASAGECQSLAFRH
MSMEG_4806|M.smegmatis_MC2_155 AVDMHVAIERARALAYFAALTIAENDPRRRLASRMAKASAGECQAVVFRH
TH_3599|M.thermoresistible__bu AADMHVAIERARALSYFAALTISVDDPRRRLAAAMAKASAGECQSLVFRH
Mflv_2491|M.gilvum_PYR-GCK ATDMYVAIERARALSYFAALTIAADDPRRRLAAAMAKASAGECQALVFKH
Mvan_4163|M.vanbaalenii_PYR-1 ATDMFVAIERARALSYFAALTIAADDPRRRLAAAMAKASAGECQSLVFRH
MAB_0594c|M.abscessus_ATCC_199 LADVHIALELARPLVYGAALSLADQSPTAARDASAAKVAAAKAAYLAARS
MLBr_00737|M.leprae_Br4923 LADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTD
.*: : : ** : *. . : :: *.. .
Mb3594|M.bovis_AF2122/97 GIQLHGGIAITWEHDMHLYFKRAHGSAQLLESPREVLRRLESEVWESP--
Rv3564|M.tuberculosis_H37Rv GIQLHGGIAITWEHDMHLYFKRAHGSAQLLESPREVLRRLESEVWESP--
MMAR_4719|M.marinum_M GLQLFGAMGFTWENDLQFALKRAKAGELMLGGAAQHRVQIAEEYRAADF-
MUL_0319|M.ulcerans_Agy99 GLQLFGAMGFTWGNDLQFALKRAKAGELMLGGAAQHRAQIAEEYRAADF-
MAV_0934|M.avium_104 GLQLHGAMGFTWENDLQFALKRAKAGELMLGGAAEHRARIAEEYRAADF-
MSMEG_4806|M.smegmatis_MC2_155 GLQLFGAMGFTWENDVQFALKRAKAGELLLGGAAEHRAVIAAEYRTTYRG
TH_3599|M.thermoresistible__bu GLQMFGAMGFTWENDLQFALKRAKAGELMLGGAAEHRAVIAEEYRTF---
Mflv_2491|M.gilvum_PYR-GCK GIQLFGAMGFTWENDLQFALKRAKAGELLLGGAAEHRAIIAEEYGRDL--
Mvan_4163|M.vanbaalenii_PYR-1 GVQLFGAMGFTWENDLQFALKRAKAGELMLGGAAEHRAMIAEEYREMV--
MAB_0594c|M.abscessus_ATCC_199 ALQTHGAIGFTAEYDLSLWILKVRALTSAWGTSEWHRARVLEAL------
MLBr_00737|M.leprae_Br4923 AVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR----
.:* .*. . * : : .: :
Mb3594|M.bovis_AF2122/97 -
Rv3564|M.tuberculosis_H37Rv -
MMAR_4719|M.marinum_M -
MUL_0319|M.ulcerans_Agy99 -
MAV_0934|M.avium_104 -
MSMEG_4806|M.smegmatis_MC2_155 L
TH_3599|M.thermoresistible__bu -
Mflv_2491|M.gilvum_PYR-GCK -
Mvan_4163|M.vanbaalenii_PYR-1 -
MAB_0594c|M.abscessus_ATCC_199 -
MLBr_00737|M.leprae_Br4923 -