For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_0898 (-)

annotation: putative acyl-CoA dehydrogenase
coordinates: 845408 - 846583
length: 391

VQLTFDADVEAFRAEFVAFLDAHLPAEAEALERPRSSSHVPEWARRWQRLLFDSGWLLPGNPPEFGGRNA
TLLQQYVYFEELGRRRIYQSFNPQGVGIIAASLLSFGTPEQKQRWAVPILRAEMTASLGMSEPGAGSDLA
SLKTRAVLDGDHFVVNGQKVWTSGAHDADVLLTFVRTDPNAPKHKGISVLLIPTDTPGVVRRPFASMCDI
DEIDFNEVFFTDARVPAENLVGELNEGWRVATGSLGHERVMLWMGYVDLLHELSADFRPADALQRDRYAT
LVMDAHALRLLGSAALAAAARGEEDVPAQSVLKLLGSEALQRASEDALEAAGSAGLVRRAVTAQVAPLNL
DSHYRSWFDRYARTFAATIAGGTSEIQRNIIAERVLGLPRN

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_0898 - - 100% (391) putative acyl-CoA dehydrogenase
M. avium 104 MAV_0935 - e-174 76.15% (390) putative acyl-CoA dehydrogenase
M. avium 104 MAV_1268 - 4e-65 40.15% (396) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3590c fadE30 1e-55 38.23% (395) acyl-CoA dehydrogenase FADE30
M. gilvum PYR-GCK Mflv_2492 - 1e-157 70.51% (390) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3560c fadE30 1e-55 38.23% (395) acyl-CoA dehydrogenase FADE30
M. leprae Br4923 MLBr_00737 fadE25 4e-24 28.28% (343) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0597 - 1e-57 38.61% (373) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_4751 - 0.0 82.23% (394) acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_4805 - 1e-166 72.56% (390) acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4023 - 1e-165 72.08% (394) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_0322 - 1e-169 80.56% (360) acyl-CoA dehydrogenase
M. vanbaalenii PYR-1 Mvan_4162 - 1e-156 69.54% (394) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3590c|M.bovis_AF2122/97           --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
Rv3560c|M.tuberculosis_H37Rv        --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MMAR_4751|M.marinum_M               -----------MQLTFDADVEAFRDEFISFLDRNLPDQAAGME---RPRS
MUL_0322|M.ulcerans_Agy99           -----------MQLTFDADVEAFRDEFISFLDRNLPDQAAGME---RPRS
MAV_0898|M.avium_104                -----------MQLTFDADVEAFRAEFVAFLDAHLPAEAEALE---RPRS
MSMEG_4805|M.smegmatis_MC2_155      -----------MQLTFDSDVEKFRAEFVAFLDANLPSEAATLE---RPRS
TH_4023|M.thermoresistible__bu      -----------MQLTFDADVEEFRAEFIAFLEANLPDEAQTLE---RPRS
Mflv_2492|M.gilvum_PYR-GCK          -----------MQLAFDSDVEEFRAEFSAFLDEHTPSAAETLE---RPRS
Mvan_4162|M.vanbaalenii_PYR-1       -----------MQLTFEPDVEEFRAEFSAFLDEHTPSAAETLE---RPRS
MLBr_00737|M.leprae_Br4923          ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
                                                    :   : .:                  :    .  

Mb3590c|M.bovis_AF2122/97           EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
Rv3560c|M.tuberculosis_H37Rv        EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
MMAR_4751|M.marinum_M               CSHVPEWARRWQRLLFDNGWLIPGNPPEFGGRNASLLQQYVHLQELARRR
MUL_0322|M.ulcerans_Agy99           CSHVPEWARRWQRLLFDNGWLIPGNPPEFGGRNASLLQQYVHLQELARRR
MAV_0898|M.avium_104                SSHVPEWARRWQRLLFDSGWLLPGNPPEFGGRNATLLQQYVYFEELGRRR
MSMEG_4805|M.smegmatis_MC2_155      VSHMPQWARDWQRLLFDNGWLLPAQPPEFGGRNANVVQQFVHLDELCRRR
TH_4023|M.thermoresistible__bu      VSHMPQWARDWQRLLFDNGWLLPAQPPEFGGRNATVLQQYVHLEELCKRR
Mflv_2492|M.gilvum_PYR-GCK          VSHMPQWARDWQRLLFDNGWLLPAQPPEFGGRNASVLQTFVHAEELCRRR
Mvan_4162|M.vanbaalenii_PYR-1       VSHMPQWAREWQRLLFDNGWLLPAQPPEFGGRNASVLQTFVHAEELCRRR
MLBr_00737|M.leprae_Br4923          VDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                      .  .        *   *      * *.**:.          :*  :  

Mb3590c|M.bovis_AF2122/97           APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
Rv3560c|M.tuberculosis_H37Rv        APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
MAB_0597|M.abscessus_ATCC_1997      APHKVNHLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPGAG
MMAR_4751|M.marinum_M               LYRSFNPQGVGIIAESLLSFGTPEQKRRWAVPILRAEMTASLGMSEPGAG
MUL_0322|M.ulcerans_Agy99           LYRSFNPQGVGIIAESLLSFGTPEQKRRWAVPILRAEMTASLGMSEPGAG
MAV_0898|M.avium_104                IYQSFNPQGVGIIAASLLSFGTPEQKQRWAVPILRAEMTASLGMSEPGAG
MSMEG_4805|M.smegmatis_MC2_155      IYHSFNPQGVNIIAASLLTFGTEEQKHRWAVPVLRGEKTASLGMSEPSAG
TH_4023|M.thermoresistible__bu      IYHSFNPQGVNIIAASLLSFGSDEQKHRWAVPVLKAEMTASLGMSEPSAG
Mflv_2492|M.gilvum_PYR-GCK          IYHSFNPQGVNIIAASLLTFGTDEQKHRWAVPVLRGERTASLGMSEPSAG
Mvan_4162|M.vanbaalenii_PYR-1       IYHSFNPQGVNIIAASLLTFGTDEQKHQWAVPVLRGERTASLGMSEPSAG
MLBr_00737|M.leprae_Br4923          ASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAG
                                       ..      :    *:  *: : :::    :       . . **  **

Mb3590c|M.bovis_AF2122/97           SDLASVATTAELD----GDQWVINGQKVWTSLAHLSQWCFVLARTEKGSQ
Rv3560c|M.tuberculosis_H37Rv        SDLASVATTAELD----GDQWVINGQKVWTSLAHLSQWCFVLARTEKGSQ
MAB_0597|M.abscessus_ATCC_1997      SDLANVSTSAVLD----GGDWVINGQKVWTSLALQSQWCFVVARTEPGSS
MMAR_4751|M.marinum_M               SDLASLKTRAVRYRDGEGDRFVVNGQKVWTSGAHDADVLLTFVRTDPDAP
MUL_0322|M.ulcerans_Agy99           SDLASLKTRAVRYRDGEGDRFVVNGQKVWTSGAHDADVLLTFVRTYPDAP
MAV_0898|M.avium_104                SDLASLKTRAVL----DGDHFVVNGQKVWTSGAHDADVLLTFVRTDPNAP
MSMEG_4805|M.smegmatis_MC2_155      SDLASLRTRAVR----DGDEFVVNGQKVWTSGAHDADWLLTFVRTDPDAP
TH_4023|M.thermoresistible__bu      SDLASLRTRAEFVSGDDGDHFVVNGQKVWTSGAHDADFLLTFVRTDPDAP
Mflv_2492|M.gilvum_PYR-GCK          SDLASLRTKAVRD----GDEFVVNGQKVWTSGAHDADFLLTFVRTDPDAP
Mvan_4162|M.vanbaalenii_PYR-1       SDLASLRTKAVLVSESGGSYFVVNGQKVWTSGAHDADFLLTFVRTDPDAP
MLBr_00737|M.leprae_Br4923          SDAASMRTRAKAD----GDDWILNGFKCWITNGGKSTWYTVMAVTDPD-K
                                    ** *.: * *       *. :::** * * : .  :    ... *  .  

Mb3590c|M.bovis_AF2122/97           RHAGLSYLLVPLDQPGVQIRPIVQITG--TAEFNEVFFDDARTDADLVVG
Rv3560c|M.tuberculosis_H37Rv        RHAGLSYLLVPLDQPGVQIRPIVQITG--TAEFNEVFFDDARTDADLVVG
MAB_0597|M.abscessus_ATCC_1997      RHKGLSYLLVPLDQPGVEIRPIIQLTG--TSEFNEVFFDNARTSADLVVG
MMAR_4751|M.marinum_M               KHKGISALLIPTDTPGVVRRPFASVCDHDDVDFNEVFFTDAAVPAENLVG
MUL_0322|M.ulcerans_Agy99           KHKGISALLIPTDTPGVVRRPFASVCDHDDVDFNEVFFTDAAAPAENLVG
MAV_0898|M.avium_104                KHKGISVLLIPTDTPGVVRRPFASMCDIDEIDFNEVFFTDARVPAENLVG
MSMEG_4805|M.smegmatis_MC2_155      KHKGISVLIVPTDTPGVVCRPFADMTGQENLDFNEVFFTDARVPAENLVG
TH_4023|M.thermoresistible__bu      KHKGISVLIIPTDLPGVVCRPFADICGPENKDFNEVFFTDVRVPAENLVG
Mflv_2492|M.gilvum_PYR-GCK          KHKGISVLLIPTDLDGVVCRPFADMTGIENLDFNEVFFTDVRVPAENLVG
Mvan_4162|M.vanbaalenii_PYR-1       KHKGISVLLIPTDLEGVVCRPFADMTGIDNLDFNEVFFTDVRVPVENLVG
MLBr_00737|M.leprae_Br4923          GANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIG
                                       *:* :::  *  *.   *  .  .      .*::* .     : ::*

Mb3590c|M.bovis_AF2122/97           APGDGWRVAMATLTFER-GVSTLGQQIVYARELSNLVELARRTAAADDPL
Rv3560c|M.tuberculosis_H37Rv        APGDGWRVAMATLTFER-GVSTLGQQIVYARELSNLVELARRTAAADDPL
MAB_0597|M.abscessus_ATCC_1997      EPGDGWRVAMGTLTFER-GVSTLGNQITYARELSRLAELAKSNGAADDPA
MMAR_4751|M.marinum_M               ELNGGWRVATGSLGHER-TMLWLGYANLLGELATDFTPAGVLQRDRYATL
MUL_0322|M.ulcerans_Agy99           ELNGGWRVATGSLGHER-TMLWLGYANLLGELATDFTPAGVLQRDHYATL
MAV_0898|M.avium_104                ELNEGWRVATGSLGHER-VMLWMGYVDLLHELSADFRPADALQRDRYATL
MSMEG_4805|M.smegmatis_MC2_155      PLNQGWKVANGSLGHER-TMMWLGFADRIDNMLADFNPRTELERDQYATT
TH_4023|M.thermoresistible__bu      PLNGGWKVANGSLGHER-TMMWLGFADRIDNIIADFTPRTPLERDQYATA
Mflv_2492|M.gilvum_PYR-GCK          PLNGGWGVANGSLGHER-TMMWLGFADRIANCIADFVPRTPLERDALASS
Mvan_4162|M.vanbaalenii_PYR-1       PLNGGWGVANGSLGHER-TMMWLGFADRIANCIADFKPKNPLERDALATS
MLBr_00737|M.leprae_Br4923          EPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESIS
                                      . *: .* .:* . *  :   .         : :              

Mb3590c|M.bovis_AF2122/97           IRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWANWHRNLGE
Rv3560c|M.tuberculosis_H37Rv        IRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWANWHRNLGE
MAB_0597|M.abscessus_ATCC_1997      IRERLAQAYVGMRTMRAYALATMD---EERPGQDNVSKLLWANWHRDLGE
MMAR_4751|M.marinum_M               VMDTQAMRLLGSATLASAARGQED------VPAQSVLKLLGSEALQRACE
MUL_0322|M.ulcerans_Agy99           VMDTQAMRLLGSATLASAARGQED------VPAQSVLKLLGSEALQRACE
MAV_0898|M.avium_104                VMDAHALRLLGSAALAAAARGEED------VPAQSVLKLLGSEALQRASE
MSMEG_4805|M.smegmatis_MC2_155      IMDYQALRALGSAALARAARGEQD------TASVSVLKLLGSEAERNAFE
TH_4023|M.thermoresistible__bu      IMDYQALRLIGSVGLAKAARGEMD------TASVSVAKLLGSEAELRAAE
Mflv_2492|M.gilvum_PYR-GCK          IMDYEALRLLGSVGIAKAARGEVD------VASVSIPKLLGAEAEQRIEG
Mvan_4162|M.vanbaalenii_PYR-1       IMDYQALRLLGSVGIAKAARGEVD------VASVSIPKLLGAEAEQRIEG
MLBr_00737|M.leprae_Br4923          TFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASD
                                      :       .       *                   :: :        

Mb3590c|M.bovis_AF2122/97           LAMDVIGKPGMTMP-----------DGEFDEWQRLYLFTRADTIYGGSNE
Rv3560c|M.tuberculosis_H37Rv        LAMDVIGKPGMTMP-----------DGEFDEWQRLYLFTRADTIYGGSNE
MAB_0597|M.abscessus_ATCC_1997      LAMEIIGTSTLLTN-----------AGEMDEWQRLFLFSRADTIYGGSNE
MMAR_4751|M.marinum_M               DALDSAGGDGLVHPSITAPIAALNLDNHYGSWFDRYARSFAGTIAGGTSE
MUL_0322|M.ulcerans_Agy99           DALDSAGGDGLVHPSITAPIAALNLDNHYGS-------------------
MAV_0898|M.avium_104                DALEAAGSAGLVRRAVTAQVAPLNLDSHYRSWFDRYARTFAATIAGGTSE
MSMEG_4805|M.smegmatis_MC2_155      NALAAAGPEGLIHPSTSGPYAHMNLDHYFASWFERYARSFGGTIAGGTSE
TH_4023|M.thermoresistible__bu      MALTAAGSDGLIHPSTTGPYAHMNLDHYFASWFERFARSFSGTIAGGTSE
Mflv_2492|M.gilvum_PYR-GCK          LALEAAGLDGLVHPATSGPYEHMNLDHYFASWFERYCRSFGGTIAGGTSE
Mvan_4162|M.vanbaalenii_PYR-1       LALEAAGPDGLVHPATSGPYEHMNLDHYFASWFERYCRSFGGTIAGGTSE
MLBr_00737|M.leprae_Br4923          IAMEVTTDAVQLFGG-----AGYTSDFPVERFMR---DAKITQIYEGTNQ
                                     *:                                               

Mb3590c|M.bovis_AF2122/97           IQRNIIAERVLGLPREAKG
Rv3560c|M.tuberculosis_H37Rv        IQRNIIAERVLGLPREAKG
MAB_0597|M.abscessus_ATCC_1997      IQRNIISERVLGLPREAR-
MMAR_4751|M.marinum_M               IQRNIIAERILGLPRG---
MUL_0322|M.ulcerans_Agy99           -------------------
MAV_0898|M.avium_104                IQRNIIAERVLGLPRN---
MSMEG_4805|M.smegmatis_MC2_155      IQRNIIATQVLGLPRG---
TH_4023|M.thermoresistible__bu      IQRNIIAQQVLGLPRR---
Mflv_2492|M.gilvum_PYR-GCK          IQRNIIAQQVLGLPRR---
Mvan_4162|M.vanbaalenii_PYR-1       IQRNIIAQQVLGLPRR---
MLBr_00737|M.leprae_Br4923          IQRVVMSRALLR-------

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_0898	-	-	100% (391)	putative acyl-CoA dehydrogenase
M. avium 104	MAV_0935	-	e-174	76.15% (390)	putative acyl-CoA dehydrogenase
M. avium 104	MAV_1268	-	4e-65	40.15% (396)	acyl-CoA dehydrogenase domain-containing protein