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M. avium 104 MAV_1268 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 1212960 - 1214129
length: 389

SGKMDFCYPAEVERFRTELRDWLSDNLTDELVKARRAGGRDDAAFEMLRAWNQTMADAGWAAVSWPREYG
GRGATVLEQLVYTEETTRARAPLPLNVIGLNNIAPAIMQYGTEAQKQRLLPRMMRADDIWCQGMSEPDAG
SDLAALRTRAVRDGDDFVVTGQKIWTSLGHRADWCQLYVRTDPDAPKHKGISCLIVDMTLPGIEARPLVT
LGGDADFAEVFFHDVRVPADALLGPLNAGWQVATTTLSHERAGAARLYAEMQVRLEELVDDLAAAGTGAL
DDPVTLRRLGELAVRIKYLEVLCQRSISATLHGGSELVALGSASLAKTVWGEIGQDLAALAFDVLGSRDD
GRAWANYRLTSRSLTIAGGTTQINKNITAQRVLGLPRK*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_1268 - - 100% (389) acyl-CoA dehydrogenase domain-containing protein
M. avium 104 MAV_2619 - 1e-74 39.80% (402) acyl-CoA dehydrogenase domain-containing protein
M. avium 104 MAV_0601 - 3e-74 39.69% (388) putative acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3590c fadE30 1e-76 39.74% (390) acyl-CoA dehydrogenase FADE30
M. gilvum PYR-GCK Mflv_1481 - 4e-77 40.00% (390) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3560c fadE30 2e-76 39.74% (390) acyl-CoA dehydrogenase FADE30
M. leprae Br4923 MLBr_00737 fadE25 8e-24 32.49% (197) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0597 - 2e-77 39.69% (388) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_5049 fadE30 4e-74 39.95% (388) acyl-CoA dehydrogenase FadE30
M. smegmatis MC2 155 MSMEG_6012 - 8e-72 39.15% (401) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4120 - 4e-80 42.27% (388) PUTATIVE putative acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_4125 fadE30 5e-73 39.43% (388) acyl-CoA dehydrogenase FadE30
M. vanbaalenii PYR-1 Mvan_5285 - 1e-72 39.03% (392) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MAV_1268|M.avium_104                -------MSGKMDFCYPAEVERFRTELRDWLSDNLTDELVKARRAGGR--
TH_4120|M.thermoresistible__bu      ------VNDRDYGVALTDADRAFRDEVREFLASSLTPDLLS--RDGG---
Mflv_1481|M.gilvum_PYR-GCK          --------------MIEV--QKFRAEVRDWLAENLVGDFAALKGLGGPGR
Mvan_5285|M.vanbaalenii_PYR-1       --------------MIEV--QEFRAEVRDWLAENLVGEYAALKGLGGPGR
MSMEG_6012|M.smegmatis_MC2_155      --------------MIEV--QEFRAEVRQWLADNLVGDFAALKGLGGPGR
Mb3590c|M.bovis_AF2122/97           --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
Rv3560c|M.tuberculosis_H37Rv        --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
MMAR_5049|M.marinum_M               --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MUL_4125|M.ulcerans_Agy99           --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MLBr_00737|M.leprae_Br4923          ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
                                                          .:   .                      

MAV_1268|M.avium_104                DDAAFEMLRAWNQTMADAGWAAVSWPREYGGRGATVLEQLVYTEETTRAR
TH_4120|M.thermoresistible__bu      ETARLDRLRRWQGLLYDAGLAAISWPTEYGGRAATPTQQLIFNTEMAAAR
Mflv_1481|M.gilvum_PYR-GCK          EHEAFEERLAWNQHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
Mvan_5285|M.vanbaalenii_PYR-1       EHEAFEERLAWNRHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
MSMEG_6012|M.smegmatis_MC2_155      EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYARAN
Mb3590c|M.bovis_AF2122/97           EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
Rv3560c|M.tuberculosis_H37Rv        EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
MMAR_5049|M.marinum_M               EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MUL_4125|M.ulcerans_Agy99           EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
MLBr_00737|M.leprae_Br4923          VDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                                  :  :*  .:  * *:**:.           * : . 

MAV_1268|M.avium_104                APLPLNVIGLNNIAPAIMQYGTEAQKQRLLPRMMRADDIWCQGMSEPDAG
TH_4120|M.thermoresistible__bu      APEPINRSAINQLGPTIIQWGTDEQRAYYLPRILSAEDVWCQGFSEPEAG
Mflv_1481|M.gilvum_PYR-GCK          APDKVNHLGEELLGPTLIAYGTPEQQQRFLPRILDVTELWSQGYSEPGAG
Mvan_5285|M.vanbaalenii_PYR-1       APDKVNHLGEELLGPTLIAYGTPEQQQRFLPKILDVTELWSQGYSEPGAG
MSMEG_6012|M.smegmatis_MC2_155      APDKVNHFGEELLGPTLIEYGTPEQQKRFLPKILDVTELWCQGYSEPNAG
Mb3590c|M.bovis_AF2122/97           APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
Rv3560c|M.tuberculosis_H37Rv        APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
MMAR_5049|M.marinum_M               APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
MUL_4125|M.ulcerans_Agy99           APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
MAB_0597|M.abscessus_ATCC_1997      APHKVNHLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPGAG
MLBr_00737|M.leprae_Br4923          ASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAG
                                    *.  :     :     ::  *:   :   ** :     : . . **  **

MAV_1268|M.avium_104                SDLAALRTRAVRD----------GDDFVVTGQKIWTSLGHRADWCQLYVR
TH_4120|M.thermoresistible__bu      SDLASLKTRAVID----------GDELVITGQKIWTSKATYANRIYLLAR
Mflv_1481|M.gilvum_PYR-GCK          SDLANVSTTATLD----------GDEWVINGQKVWTSLAHWAQWCFVVAR
Mvan_5285|M.vanbaalenii_PYR-1       SDLANVSTTAVLDE--------EGRQWHINGQKVWTSLAHWAQWCFVVAR
MSMEG_6012|M.smegmatis_MC2_155      SDLANVSTTAELVGDAEASGATGNQYWVINGQKVWTSLAHWAQWCFVVAR
Mb3590c|M.bovis_AF2122/97           SDLASVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVLAR
Rv3560c|M.tuberculosis_H37Rv        SDLASVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVLAR
MMAR_5049|M.marinum_M               SDLANVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
MUL_4125|M.ulcerans_Agy99           SDLANVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
MAB_0597|M.abscessus_ATCC_1997      SDLANVSTSAVLD----------GGDWVINGQKVWTSLALQSQWCFVVAR
MLBr_00737|M.leprae_Br4923          SDAASMRTRAKAD----------GDDWILNGFKCWITNGGKSTWYTVMAV
                                    ** * : * *             .    :.* * * : .  :    : . 

MAV_1268|M.avium_104                TDPDAPKHKGISCLIVDMTLPGIEARPLVTLGGD--ADFAEVFFHDVRVP
TH_4120|M.thermoresistible__bu      TDPDAPKREGISYILADLNTPGIEVRPIRQITGA--SEFCEVFLDSVRVP
Mflv_1481|M.gilvum_PYR-GCK          TEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTA
Mvan_5285|M.vanbaalenii_PYR-1       TEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTD
MSMEG_6012|M.smegmatis_MC2_155      TEKGSKRHAGLSYLLVPLDQPGVEIRPINQLTGD--SEFNEVFFDDARTE
Mb3590c|M.bovis_AF2122/97           TEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
Rv3560c|M.tuberculosis_H37Rv        TEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
MMAR_5049|M.marinum_M               TEKGSKRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
MUL_4125|M.ulcerans_Agy99           TEKGSKRHAGLSYLLVPLDQPSVQIRPIVQITGT--AEFNEVFFDDARTD
MAB_0597|M.abscessus_ATCC_1997      TEPGSSRHKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNARTS
MLBr_00737|M.leprae_Br4923          TDPDKGAN-GISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIP
                                    *: .   . *:* ::.     ...  *     *   :   *:::.. *  

MAV_1268|M.avium_104                ADALLGPLNAGWQVATTTLSHERA--GAARLYAEMQVR--LEELVDDLAA
TH_4120|M.thermoresistible__bu      LANVLGPLHGGWRVAKSTLGYERV--GQSRTHRIERRLGILVKMAQEPNA
Mflv_1481|M.gilvum_PYR-GCK          ADLVVGEPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVE--LA
Mvan_5285|M.vanbaalenii_PYR-1       ADLVVGEPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVE--LA
MSMEG_6012|M.smegmatis_MC2_155      AGLVVGQPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVE--LA
Mb3590c|M.bovis_AF2122/97           ADLVVGAPGDGWRVAMATLTFER---GVSTLGQQIVYARELSNLVE--LA
Rv3560c|M.tuberculosis_H37Rv        ADLVVGAPGDGWRVAMATLTFER---GVSTLGQQIVYARELSNLVE--LA
MMAR_5049|M.marinum_M               ADLVVGAPGDGWRVAMGTLTFER---GVSTLGQQIVYARELSDLAA--LA
MUL_4125|M.ulcerans_Agy99           ADLVVGAPGDGWRVAMGTLTFER---GVSTLGQQIVYARELSDLAA--LA
MAB_0597|M.abscessus_ATCC_1997      ADLVVGEPGDGWRVAMGTLTFER---GVSTLGNQITYARELSRLAE--LA
MLBr_00737|M.leprae_Br4923          GDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQ
                                       ::*    *::.*  ** . *   *                 .     

MAV_1268|M.avium_104                AGTGALDDPVTLRRLGELAVRIKYLEVLCQRSISATLHGGSELVALG-SA
TH_4120|M.thermoresistible__bu      LTDSGFDDSYVADRIVRYAAQVEALRQIAAQATAAGVRG----VAPGPEA
Mflv_1481|M.gilvum_PYR-GCK          EKTGAADDPLIRERLVRSWAGLKAMRSYALATMD---------VEKPGQD
Mvan_5285|M.vanbaalenii_PYR-1       KRTGAADDPLIRERLTRSWAGLKAMRSYALATMD---------VEQPGMD
MSMEG_6012|M.smegmatis_MC2_155      KRTGAADDPLIRERLVQSWTGLQAMRSYALATMD---------VEQPGQD
Mb3590c|M.bovis_AF2122/97           RRTAAADDPLIRERLTRAWTGLRAMRSYALATMEG------PAVEQPGQD
Rv3560c|M.tuberculosis_H37Rv        RRTAAADDPLIRERLTRAWTGLRAMRSYALATMEG------PAVEQPGQD
MMAR_5049|M.marinum_M               RRTGAADDPFIRERLTRAWTGLRAMRSYALATMD---------VEQPGQD
MUL_4125|M.ulcerans_Agy99           RRTGAADDPFIREHLTRAWTGLRAMRSYALATMD---------VEQPGQD
MAB_0597|M.abscessus_ATCC_1997      KSNGAADDPAIRERLAQAYVGMRTMRAYALATMD---------EERPGQD
MLBr_00737|M.leprae_Br4923          FGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERG---EPDLGFIS
                                       .          :      :.  .     :                  

MAV_1268|M.avium_104                SLAKTVWGEIGQDLAALAFDVLGSR---DDGRAWANYR-------LTSRS
TH_4120|M.thermoresistible__bu      SVAKLLTSEVDQSMANFGVELAGAPGVLERGSPGAAKRGNVAASYLLMRA
Mflv_1481|M.gilvum_PYR-GCK          NISKLLWANWHRELGEIAMDIEGAAGLTLPDGEFSEWQR----LYLFSRS
Mvan_5285|M.vanbaalenii_PYR-1       NVSKLLWANWHRELGEIAMDVQGMAGLTLPGGEFDEWQR----LYLFSRS
MSMEG_6012|M.smegmatis_MC2_155      NVSKLLWANWHRELGEIAMDVQGMAGLTLENGEFDEWQR----LYLFSRA
Mb3590c|M.bovis_AF2122/97           NVSKLLWANWHRNLGELAMDVIGKPGMTMPDGEFDEWQR----LYLFTRA
Rv3560c|M.tuberculosis_H37Rv        NVSKLLWANWHRNLGELAMDVIGKPGMTMPDGEFDEWQR----LYLFTRA
MMAR_5049|M.marinum_M               NVSKLLWANWHRSLGELAMDVIGKPGLTLADGEFDEWQR----LFLFTRA
MUL_4125|M.ulcerans_Agy99           NVSKLLWANWHRSLGELAMDVIGKPGLTLADGEFDEWQR----LFLFTRA
MAB_0597|M.abscessus_ATCC_1997      NVSKLLWANWHRDLGELAMEIIGTSTLLTNAGEMDEWQR----LFLFSRA
MLBr_00737|M.leprae_Br4923          AASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRD--------AKI
                                      :* . .:   .:   ..:: *              :          : 

MAV_1268|M.avium_104                LTIAGGTTQINKNITAQRVLGLPRK---
TH_4120|M.thermoresistible__bu      ATFGAGTSEIQRNVIAERLLGLPRDN--
Mflv_1481|M.gilvum_PYR-GCK          DTIYGGSNEIQRNIIAERVLGLPREARH
Mvan_5285|M.vanbaalenii_PYR-1       DTIYGGSNEIQRNIIAERVLGLPREAKG
MSMEG_6012|M.smegmatis_MC2_155      DTIYGGSNEIQRNIIAERVLGLPREVKG
Mb3590c|M.bovis_AF2122/97           DTIYGGSNEIQRNIIAERVLGLPREAKG
Rv3560c|M.tuberculosis_H37Rv        DTIYGGSNEIQRNIIAERVLGLPREAKG
MMAR_5049|M.marinum_M               DTIYGGSNEIQRNIIAERVLGLPREAKG
MUL_4125|M.ulcerans_Agy99           DTIYGGSNEIQRNIIAERVLGLPREAKG
MAB_0597|M.abscessus_ATCC_1997      DTIYGGSNEIQRNIISERVLGLPREAR-
MLBr_00737|M.leprae_Br4923          TQIYEGTNQIQRVVMSRALLR-------
                                      :  *:.:*:: : :. :*

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_1268	-	-	100% (389)	acyl-CoA dehydrogenase domain-containing protein
M. avium 104	MAV_2619	-	1e-74	39.80% (402)	acyl-CoA dehydrogenase domain-containing protein
M. avium 104	MAV_0601	-	3e-74	39.69% (388)	putative acyl-CoA dehydrogenase