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QLTFDSDVEKFRAEFVAFLDANLPSEAATLERPRSVSHMPQWARDWQRLLFDNGWLLPAQPPEFGGRNAN VVQQFVHLDELCRRRIYHSFNPQGVNIIAASLLTFGTEEQKHRWAVPVLRGEKTASLGMSEPSAGSDLAS LRTRAVRDGDEFVVNGQKVWTSGAHDADWLLTFVRTDPDAPKHKGISVLIVPTDTPGVVCRPFADMTGQE NLDFNEVFFTDARVPAENLVGPLNQGWKVANGSLGHERTMMWLGFADRIDNMLADFNPRTELERDQYATT IMDYQALRALGSAALARAARGEQDTASVSVLKLLGSEAERNAFENALAAAGPEGLIHPSTSGPYAHMNLD HYFASWFERYARSFGGTIAGGTSEIQRNIIATQVLGLPRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4805 | - | - | 100% (391) | acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5619 | - | 5e-55 | 36.75% (400) | acyl-CoA dehydrogenase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2191 | - | 4e-49 | 32.55% (427) | acyl-CoA dehydrogenase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3590c | fadE30 | 6e-54 | 36.39% (393) | acyl-CoA dehydrogenase FADE30 |
| M. gilvum PYR-GCK | Mflv_2492 | - | 0.0 | 84.87% (390) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3560c | fadE30 | 6e-54 | 36.39% (393) | acyl-CoA dehydrogenase FADE30 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 7e-26 | 29.15% (343) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0597 | - | 1e-52 | 35.20% (392) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_4718 | - | 0.0 | 78.77% (391) | acyl-CoA dehydrogenase |
| M. avium 104 | MAV_0935 | - | 0.0 | 81.33% (391) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4023 | - | 0.0 | 85.79% (394) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_0322 | - | 1e-147 | 69.17% (360) | acyl-CoA dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4162 | - | 0.0 | 81.98% (394) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3590c|M.bovis_AF2122/97 --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
Rv3560c|M.tuberculosis_H37Rv --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
MAB_0597|M.abscessus_ATCC_1997 MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
Mflv_2492|M.gilvum_PYR-GCK -----------MQLAFDSDVEEFRAEFSAFLDEHTPSAAETLE---RPRS
Mvan_4162|M.vanbaalenii_PYR-1 -----------MQLTFEPDVEEFRAEFSAFLDEHTPSAAETLE---RPRS
MSMEG_4805|M.smegmatis_MC2_155 -----------MQLTFDSDVEKFRAEFVAFLDANLPSEAATLE---RPRS
TH_4023|M.thermoresistible__bu -----------MQLTFDADVEEFRAEFIAFLEANLPDEAQTLE---RPRS
MMAR_4718|M.marinum_M -----------MQLTFDPDVEAFRTEFATFLDEHLPPASETVE---RPRS
MAV_0935|M.avium_104 -----------MQLTFDPDVEAFRAEFAAFLDENLPPASETLE---RPRS
MUL_0322|M.ulcerans_Agy99 -----------MQLTFDADVEAFRDEFISFLDRNLPDQAAGME---RPRS
MLBr_00737|M.leprae_Br4923 ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
: : .: : .
Mb3590c|M.bovis_AF2122/97 EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
Rv3560c|M.tuberculosis_H37Rv EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
MAB_0597|M.abscessus_ATCC_1997 EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
Mflv_2492|M.gilvum_PYR-GCK VSHMPQWARDWQRLLFDNGWLLPAQPPEFGGRNASVLQTFVHAEELCRRR
Mvan_4162|M.vanbaalenii_PYR-1 VSHMPQWAREWQRLLFDNGWLLPAQPPEFGGRNASVLQTFVHAEELCRRR
MSMEG_4805|M.smegmatis_MC2_155 VSHMPQWARDWQRLLFDNGWLLPAQPPEFGGRNANVVQQFVHLDELCRRR
TH_4023|M.thermoresistible__bu VSHMPQWARDWQRLLFDNGWLLPAQPPEFGGRNATVLQQYVHLEELCKRR
MMAR_4718|M.marinum_M VSHLPQWARRWQRLLFDNGWLLPGQPPEFGGRNATVVQQFVHLEELCRRR
MAV_0935|M.avium_104 VSHMPQWARRWQRLLFDNGWLLPSQPPEYGGRNATVLQQFVYLEELSRRR
MUL_0322|M.ulcerans_Agy99 CSHVPEWARRWQRLLFDNGWLIPGNPPEFGGRNASLLQQYVHLQELARRR
MLBr_00737|M.leprae_Br4923 VDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
. . * * * *.**:. :* .:
Mb3590c|M.bovis_AF2122/97 APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
Rv3560c|M.tuberculosis_H37Rv APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
MAB_0597|M.abscessus_ATCC_1997 APHKVNHLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPGAG
Mflv_2492|M.gilvum_PYR-GCK IYHSFNPQGVNIIAASLLTFGTDEQKHRWAVPVLRGERTASLGMSEPSAG
Mvan_4162|M.vanbaalenii_PYR-1 IYHSFNPQGVNIIAASLLTFGTDEQKHQWAVPVLRGERTASLGMSEPSAG
MSMEG_4805|M.smegmatis_MC2_155 IYHSFNPQGVNIIAASLLTFGTEEQKHRWAVPVLRGEKTASLGMSEPSAG
TH_4023|M.thermoresistible__bu IYHSFNPQGVNIIAASLLSFGSDEQKHRWAVPVLKAEMTASLGMSEPSAG
MMAR_4718|M.marinum_M IYHSLNPQGVNIVAASILSFGTDEQKLRWAVPILRAQITASLGMSEPSAG
MAV_0935|M.avium_104 IYHSFNPQGVNIVAASLLSFGSDEQKQRWAVPILRAEITASLGMSEPSAG
MUL_0322|M.ulcerans_Agy99 LYRSFNPQGVGIIAESLLSFGTPEQKRRWAVPILRAEMTASLGMSEPGAG
MLBr_00737|M.leprae_Br4923 ASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAG
.. : :: *: : : : : . . ** **
Mb3590c|M.bovis_AF2122/97 SDLASVATTAELD----GDQWVINGQKVWTSLAHLSQWCFVLARTEKGSQ
Rv3560c|M.tuberculosis_H37Rv SDLASVATTAELD----GDQWVINGQKVWTSLAHLSQWCFVLARTEKGSQ
MAB_0597|M.abscessus_ATCC_1997 SDLANVSTSAVLD----GGDWVINGQKVWTSLALQSQWCFVVARTEPGSS
Mflv_2492|M.gilvum_PYR-GCK SDLASLRTKAVRD----GDEFVVNGQKVWTSGAHDADFLLTFVRTDPDAP
Mvan_4162|M.vanbaalenii_PYR-1 SDLASLRTKAVLVSESGGSYFVVNGQKVWTSGAHDADFLLTFVRTDPDAP
MSMEG_4805|M.smegmatis_MC2_155 SDLASLRTRAVRD----GDEFVVNGQKVWTSGAHDADWLLTFVRTDPDAP
TH_4023|M.thermoresistible__bu SDLASLRTRAEFVSGDDGDHFVVNGQKVWTSGAHDADFLLTFVRTDPDAP
MMAR_4718|M.marinum_M SDLASLRTRAVLD----GDHFVVNGQKVWTSGAHDADVLLTFVRTDPDAP
MAV_0935|M.avium_104 SDLASLRTRAVLD----GDHFVVNGQKVWTSGAHDADVLLTFVRTDPDAP
MUL_0322|M.ulcerans_Agy99 SDLASLKTRAVRYRDGEGDRFVVNGQKVWTSGAHDADVLLTFVRTYPDAP
MLBr_00737|M.leprae_Br4923 SDAASMRTRAKAD----GDDWILNGFKCWITNGGKSTWYTVMAVTDPD-K
** *.: * * *. :::** * * : . : ... * .
Mb3590c|M.bovis_AF2122/97 RHAGLSYLLVPLDQPGVQIRPIVQITG--TAEFNEVFFDDARTDADLVVG
Rv3560c|M.tuberculosis_H37Rv RHAGLSYLLVPLDQPGVQIRPIVQITG--TAEFNEVFFDDARTDADLVVG
MAB_0597|M.abscessus_ATCC_1997 RHKGLSYLLVPLDQPGVEIRPIIQLTG--TSEFNEVFFDNARTSADLVVG
Mflv_2492|M.gilvum_PYR-GCK KHKGISVLLIPTDLDGVVCRPFADMTGIENLDFNEVFFTDVRVPAENLVG
Mvan_4162|M.vanbaalenii_PYR-1 KHKGISVLLIPTDLEGVVCRPFADMTGIDNLDFNEVFFTDVRVPVENLVG
MSMEG_4805|M.smegmatis_MC2_155 KHKGISVLIVPTDTPGVVCRPFADMTGQENLDFNEVFFTDARVPAENLVG
TH_4023|M.thermoresistible__bu KHKGISVLIIPTDLPGVVCRPFADICGPENKDFNEVFFTDVRVPAENLVG
MMAR_4718|M.marinum_M KHKGISALLIPTDTAGVVRRPFPSICSADDLDFNEVFFSDVLVPAANLVG
MAV_0935|M.avium_104 KHKGISALVIPTDTPGLVRRPFPSICSIDDKDFNEVFFTDVRVPAENLVG
MUL_0322|M.ulcerans_Agy99 KHKGISALLIPTDTPGVVRRPFASVCDHDDVDFNEVFFTDAAAPAENLVG
MLBr_00737|M.leprae_Br4923 GANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIG
*:* ::: * *. * . . .*::* . ::*
Mb3590c|M.bovis_AF2122/97 APGDGWRVAMATLTFERGVSTLGQQIVYARELSNLVELARRTAAADDPLI
Rv3560c|M.tuberculosis_H37Rv APGDGWRVAMATLTFERGVSTLGQQIVYARELSNLVELARRTAAADDPLI
MAB_0597|M.abscessus_ATCC_1997 EPGDGWRVAMGTLTFERGVSTLGNQITYARELSRLAELAKSNGAADDPAI
Mflv_2492|M.gilvum_PYR-GCK PLNGGWGVANGSLGHERTMMWLGFADRIANCIADFVPRTPLERDALASSI
Mvan_4162|M.vanbaalenii_PYR-1 PLNGGWGVANGSLGHERTMMWLGFADRIANCIADFKPKNPLERDALATSI
MSMEG_4805|M.smegmatis_MC2_155 PLNQGWKVANGSLGHERTMMWLGFADRIDNMLADFNPRTELERDQYATTI
TH_4023|M.thermoresistible__bu PLNGGWKVANGSLGHERTMMWLGFADRIDNIIADFTPRTPLERDQYATAI
MMAR_4718|M.marinum_M ALNGGWRVANGSLGHERTMMWLGFADRLDNLIADLHPVTELDHDRYATMV
MAV_0935|M.avium_104 GLNQGWLVANGSLGHERTMMWLGFADRLENMIADFQPGTEVERDQYATTI
MUL_0322|M.ulcerans_Agy99 ELNGGWRVATGSLGHERTMLWLGYANLLGELATDFTPAGVLQRDHYATLV
MLBr_00737|M.leprae_Br4923 EPGTGFKTALATLDHTRPTIG-AQAVGIAQGALDAAIVYTKDRKQFGESI
. *: .* .:* . * . . :
Mb3590c|M.bovis_AF2122/97 RERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWANWHRNLGEL
Rv3560c|M.tuberculosis_H37Rv RERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWANWHRNLGEL
MAB_0597|M.abscessus_ATCC_1997 RERLAQAYVGMRTMRAYALATMD---EERPGQDNVSKLLWANWHRDLGEL
Mflv_2492|M.gilvum_PYR-GCK MDYEALRLLGSVGIAKAARGEVD------VASVSIPKLLGAEAEQRIEGL
Mvan_4162|M.vanbaalenii_PYR-1 MDYQALRLLGSVGIAKAARGEVD------VASVSIPKLLGAEAEQRIEGL
MSMEG_4805|M.smegmatis_MC2_155 MDYQALRALGSAALARAARGEQD------TASVSVLKLLGSEAERNAFEN
TH_4023|M.thermoresistible__bu MDYQALRLIGSVGLAKAARGEMD------TASVSVAKLLGSEAELRAAEM
MMAR_4718|M.marinum_M MDKQALRLLGSVALARASRGEDD------TSAISVLKLLGSEAELRASEH
MAV_0935|M.avium_104 MDRQALRLLGSAALARAARGEDD------VAAISVLKLLGSEAELRAMEL
MUL_0322|M.ulcerans_Agy99 MDTQAMRLLGSATLASAARGQED------VPAQSVLKLLGSEALQRACED
MLBr_00737|M.leprae_Br4923 STFQSIQFMLADMAMKVEAARLI-------VYAAAARAERGEPDLGFISA
: . : .:
Mb3590c|M.bovis_AF2122/97 AMDVIGKPGMTMPDGE-----------FDEWQRLYLF-TRADTIYGGSNE
Rv3560c|M.tuberculosis_H37Rv AMDVIGKPGMTMPDGE-----------FDEWQRLYLF-TRADTIYGGSNE
MAB_0597|M.abscessus_ATCC_1997 AMEIIGTSTLLTNAGE-----------MDEWQRLFLF-SRADTIYGGSNE
Mflv_2492|M.gilvum_PYR-GCK ALEAAGLDGLVHPATSGPYEHMNLDHYFASWFERYCR-SFGGTIAGGTSE
Mvan_4162|M.vanbaalenii_PYR-1 ALEAAGPDGLVHPATSGPYEHMNLDHYFASWFERYCR-SFGGTIAGGTSE
MSMEG_4805|M.smegmatis_MC2_155 ALAAAGPEGLIHPSTSGPYAHMNLDHYFASWFERYAR-SFGGTIAGGTSE
TH_4023|M.thermoresistible__bu ALTAAGSDGLIHPSTTGPYAHMNLDHYFASWFERFAR-SFSGTIAGGTSE
MMAR_4718|M.marinum_M ALAAAGSDGLIHPALTGPYAPMNLDHYFASWFERYAR-SFSGTIAGGTSE
MAV_0935|M.avium_104 ALTSAGADGLVHPGQTGPYAHMNLDHYFASWFERYAR-SFSGTIAGGTLE
MUL_0322|M.ulcerans_Agy99 ALDSAGGDGLVHPSITAPIAALNLDNHYGS--------------------
MLBr_00737|M.leprae_Br4923 ASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQ
* .
Mb3590c|M.bovis_AF2122/97 IQRNIIAERVLGLPREAKG
Rv3560c|M.tuberculosis_H37Rv IQRNIIAERVLGLPREAKG
MAB_0597|M.abscessus_ATCC_1997 IQRNIISERVLGLPREAR-
Mflv_2492|M.gilvum_PYR-GCK IQRNIIAQQVLGLPRR---
Mvan_4162|M.vanbaalenii_PYR-1 IQRNIIAQQVLGLPRR---
MSMEG_4805|M.smegmatis_MC2_155 IQRNIIATQVLGLPRG---
TH_4023|M.thermoresistible__bu IQRNIIAQQVLGLPRR---
MMAR_4718|M.marinum_M IQRNIIAQRVLGLPRG---
MAV_0935|M.avium_104 IQRNIIAQRVLGLPRG---
MUL_0322|M.ulcerans_Agy99 -------------------
MLBr_00737|M.leprae_Br4923 IQRVVMSRALLR-------