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MTTIGRPVRTERASSTQEAILVAAERLYAEHGMFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHK HRGPVEQLREQMVADLLESGAGGGRDAELRSWVACLVRPLTDHLEELGNPTWYARFAAQAMTDPAYYNII VKGALSSPSLVQVVEGINRCLPDLPAEVHFERNIMARNLLMHTCADRERALAAGTSTSHRSWRAAASGLI DAIVGLWLAPVTPYE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0887 | - | - | 100% (225) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2967 | - | 5e-74 | 62.56% (219) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2626 | - | 8e-17 | 28.44% (218) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 2e-06 | 34.51% (113) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_2416 | - | 1e-90 | 74.09% (220) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 2e-06 | 34.51% (113) | hypothetical protein Rv1685c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0835c | - | 8e-11 | 32.21% (149) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4764 | - | 2e-97 | 79.11% (225) | hypothetical protein MMAR_4764 |
| M. smegmatis MC2 155 | MSMEG_4858 | - | 5e-93 | 75.91% (220) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2278 | - | 2e-85 | 72.27% (220) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0335 | - | 2e-96 | 77.78% (225) | hypothetical protein MUL_0335 |
| M. vanbaalenii PYR-1 | Mvan_4236 | - | 9e-92 | 75.00% (220) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4764|M.marinum_M -----------------------------MTAVGRAVRGERASSTQEAIL
MUL_0335|M.ulcerans_Agy99 -----------------------------MTAVGRAVRGERASSTQEAIL
MAV_0887|M.avium_104 -----------------------------MTTIGRPVRTERASSTQEAIL
Mflv_2416|M.gilvum_PYR-GCK MQSGATTFLNGTTHLKQSLDLPGVTRFTDRVTTARTVRADRATGTQEAIL
Mvan_4236|M.vanbaalenii_PYR-1 -----MSFLN------QSLDLVGVTGFTEWVTTARTVRADRASSTQEAIL
MSMEG_4858|M.smegmatis_MC2_155 ----MTRFTG----------LVTTASRTASRTAARTARADRATSTQEAIL
TH_2278|M.thermoresistible__bu -----------------------VVQFTEGVTAARTVRADRASSTQEAIL
Mb1711c|M.bovis_AF2122/97 -------------------------MAAPDNSRRRPGRPAGSSDTRERIL
Rv1685c|M.tuberculosis_H37Rv -------------------------MAAPDNSRRRPGRPAGSSDTRERIL
MAB_0835c|M.abscessus_ATCC_199 -----------------------------MTDTSAETTILTEDSTDQRLL
.* : :*
MMAR_4764|M.marinum_M VAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MUL_0335|M.ulcerans_Agy99 VAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MAV_0887|M.avium_104 VAAERLYAEHGMFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
Mflv_2416|M.gilvum_PYR-GCK KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
Mvan_4236|M.vanbaalenii_PYR-1 KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
MSMEG_4858|M.smegmatis_MC2_155 KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEHKH
TH_2278|M.thermoresistible__bu KAAERLYAERGMFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
Mb1711c|M.bovis_AF2122/97 SSARELFAHNGIDRTSIRAVAAKAG-VDAALVHHYFGTKQQLFAAAIHIP
Rv1685c|M.tuberculosis_H37Rv SSARELFAHNGIDRTSIRAVAAKAG-VDAALVHHYFGTKQQLFAAAIHIP
MAB_0835c|M.abscessus_ATCC_199 NAAERLFAERGVDAVSLRAIMAAAG-TNVASVHYHFGSKERLIEALLDRY
:*..*:*..*: .* * : ** : * * ::**:* *. * .
MMAR_4764|M.marinum_M RVPVERLREQMVA----AAAAKGVAATMRDWVACLVCPLTEHLAVLGNPT
MUL_0335|M.ulcerans_Agy99 RVPIERLREQMVA----AAAAKGAAATMRDWVACLVCPLTEHLAVLGNPT
MAV_0887|M.avium_104 RGPVEQLREQMVADLLESGAGGGRDAELRSWVACLVRPLTDHLEELGNPT
Mflv_2416|M.gilvum_PYR-GCK RGPIEELREQRVA-------AIDSSGDMRDWVAALVCPLTDHLAALGNPT
Mvan_4236|M.vanbaalenii_PYR-1 RGPIEELREQRVA-------AIGASTDMRDWVAALVCPLTDHLAALGNPT
MSMEG_4858|M.smegmatis_MC2_155 RGPIEYLREQMIG-------TVQGSTDLRDWVGALVRPLTDHLAALGNPT
TH_2278|M.thermoresistible__bu RVEIERLLEKMVA-------ETGDSTDLRDWVACLVCSLTEHLHQLGNPT
Mb1711c|M.bovis_AF2122/97 IDPMVIIGPIREAP---------------------VEELGYKLPSLLLPI
Rv1685c|M.tuberculosis_H37Rv IDPMVIIGPIREAP---------------------VEELGYKLPSLLLPI
MAB_0835c|M.abscessus_ATCC_199 LDQIEKRRFALLD-------VAETARTLRAIAEAIVTPLS-EIAEEGSTA
: * * .: .
MMAR_4764|M.marinum_M WYARFAAQAMT-DPAYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRY
MUL_0335|M.ulcerans_Agy99 WYARFAAQAMT-DPAYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRY
MAV_0887|M.avium_104 WYARFAAQAMT-DPAYYNIIVKGALSSPSLVQVVEGINRCLPDLPAEVHF
Mflv_2416|M.gilvum_PYR-GCK WYARFAAQVMT-DPAYHNMIVKDALSSPSLVRVLDGINGCLPDLPVDVRV
Mvan_4236|M.vanbaalenii_PYR-1 WYARFAAQVMT-DPAYHNMIVKDALSSPSLVRVLDGINSCLPDLPVDVRV
MSMEG_4858|M.smegmatis_MC2_155 WYARFAAQVMT-DPAYHNIIVRDALSSPSLVQVIEGMNNCLPDLPAEIRA
TH_2278|M.thermoresistible__bu WYARFAAQALA-DPAYQKIVVKDALASPALVRVVEGITRCLPDLPAAVVV
Mb1711c|M.bovis_AF2122/97 WDSELGAGLIA-TLRSLISGSDVGLARSFLEEVVTVELGSRVDNPPGTGK
Rv1685c|M.tuberculosis_H37Rv WDSELGAGLIA-TLRSLISGSDVGLARSFLEEVVTVELGSRVDNPPGTGK
MAB_0835c|M.abscessus_ATCC_199 WLSTLGKLLISGHPALIPMSVSFQPQAARLQELILRLRPDATLPSIRFGV
* : :. :: . * .:: .
MMAR_4764|M.marinum_M ERNLMARNLLMHTCADL--ERALAAGTSVPRPSWREAATGLIDAITGLWL
MUL_0335|M.ulcerans_Agy99 ERNLMARNLLMHTCADL--ERALAAGTSVPRPFWREAATGQIDAITGLWL
MAV_0887|M.avium_104 ERNIMARNLLMHTCADR--ERALAAGTSTSHRSWRAAASGLIDAIVGLWL
Mflv_2416|M.gilvum_PYR-GCK ERNIMGRNLLMHSCADR--ERLLAQGSPVPRGSWQSAATGLIDAIIGLWH
Mvan_4236|M.vanbaalenii_PYR-1 ERNIMGRNLLMHSCADR--ERLLAQGAPVARPSWQAAATGLIDAIIGLWH
MSMEG_4858|M.smegmatis_MC2_155 ERNIMARNLLMHSCAER--ERALAQGAPVPRSSWQGAASGLIDAIVGLWL
TH_2278|M.thermoresistible__bu ERNIMARNLLMHTCADF--ERAFAEGDPVPRASWQAVGNGLIDAIVGLWR
Mb1711c|M.bovis_AF2122/97 IRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLTGELP
Rv1685c|M.tuberculosis_H37Rv IRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLTGELP
MAB_0835c|M.abscessus_ATCC_199 THAVTLTCVVLGDIAHT--NRLMSLSGTYLDD--GQMNAQLIDMVTAILA
: :: * . . : .
MMAR_4764|M.marinum_M APVTARE-
MUL_0335|M.ulcerans_Agy99 APVTARE-
MAV_0887|M.avium_104 APVTPYE-
Mflv_2416|M.gilvum_PYR-GCK APVTERP-
Mvan_4236|M.vanbaalenii_PYR-1 APVTEPA-
MSMEG_4858|M.smegmatis_MC2_155 APVTGEDR
TH_2278|M.thermoresistible__bu APVTEPPQ
Mb1711c|M.bovis_AF2122/97 DDLAP---
Rv1685c|M.tuberculosis_H37Rv DDLAP---
MAB_0835c|M.abscessus_ATCC_199 GPPDES--