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SFLNQSLDLVGVTGFTEWVTTARTVRADRASSTQEAILKAAERLYAEHGVFAVSNRQVSEAAGQGNNAAV GYHFGTKADLVRAIEHKHRGPIEELREQRVAAIGASTDMRDWVAALVCPLTDHLAALGNPTWYARFAAQV MTDPAYHNMIVKDALSSPSLVRVLDGINSCLPDLPVDVRVERNIMGRNLLMHSCADRERLLAQGAPVARP SWQAAATGLIDAIIGLWHAPVTEPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4236 | - | - | 100% (236) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2880 | - | 3e-07 | 39.13% (92) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2416 | - | 1e-122 | 93.51% (231) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0835c | - | 6e-12 | 32.87% (143) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4764 | - | 2e-96 | 81.22% (213) | hypothetical protein MMAR_4764 |
| M. avium 104 | MAV_0887 | - | 8e-92 | 75.00% (220) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4858 | - | 1e-103 | 80.00% (230) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2278 | - | 8e-95 | 76.23% (223) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0335 | - | 1e-95 | 81.22% (213) | hypothetical protein MUL_0335 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4236|M.vanbaalenii_PYR-1 -----MSFLN------QSLDLVGVTGFTEWVTTARTVRADRASSTQEAIL
Mflv_2416|M.gilvum_PYR-GCK MQSGATTFLNGTTHLKQSLDLPGVTRFTDRVTTARTVRADRATGTQEAIL
MMAR_4764|M.marinum_M -----MT------------------------AVGRAVRGERASSTQEAIL
MUL_0335|M.ulcerans_Agy99 -----MT------------------------AVGRAVRGERASSTQEAIL
MAV_0887|M.avium_104 -----MT------------------------TIGRPVRTERASSTQEAIL
MSMEG_4858|M.smegmatis_MC2_155 -----MTRFTG---------LVTTASRTASRTAARTARADRATSTQEAIL
TH_2278|M.thermoresistible__bu --VVQFTEG---------------------VTAARTVRADRASSTQEAIL
MAB_0835c|M.abscessus_ATCC_199 -----MT------------------------DTSAETTILTEDSTDQRLL
: . . .*:: :*
Mvan_4236|M.vanbaalenii_PYR-1 KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
Mflv_2416|M.gilvum_PYR-GCK KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
MMAR_4764|M.marinum_M VAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MUL_0335|M.ulcerans_Agy99 VAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MAV_0887|M.avium_104 VAAERLYAEHGMFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIEHKH
MSMEG_4858|M.smegmatis_MC2_155 KAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEHKH
TH_2278|M.thermoresistible__bu KAAERLYAERGMFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIEQKH
MAB_0835c|M.abscessus_ATCC_199 NAAERLFAERGVDAVSLRAIMAAAG-TNVASVHYHFGSKERLIEALLDRY
*****:**:*: *** * : *** * *:* ****:* *:.*: .::
Mvan_4236|M.vanbaalenii_PYR-1 RGPIEELREQRVA-------AIGASTDMRDWVAALVCPLTDHLAALGNPT
Mflv_2416|M.gilvum_PYR-GCK RGPIEELREQRVA-------AIDSSGDMRDWVAALVCPLTDHLAALGNPT
MMAR_4764|M.marinum_M RVPVERLREQMVA----AAAAKGVAATMRDWVACLVCPLTEHLAVLGNPT
MUL_0335|M.ulcerans_Agy99 RVPIERLREQMVA----AAAAKGAAATMRDWVACLVCPLTEHLAVLGNPT
MAV_0887|M.avium_104 RGPVEQLREQMVADLLESGAGGGRDAELRSWVACLVRPLTDHLEELGNPT
MSMEG_4858|M.smegmatis_MC2_155 RGPIEYLREQMIG------TVQG-STDLRDWVGALVRPLTDHLAALGNPT
TH_2278|M.thermoresistible__bu RVEIERLLEKMVA-------ETGDSTDLRDWVACLVCSLTEHLHQLGNPT
MAB_0835c|M.abscessus_ATCC_199 LDQIEKRRFALLD-------VAETARTLRAIAEAIVTPLS-EIAEEGSTA
:* : :* . .:* .*: .: *..:
Mvan_4236|M.vanbaalenii_PYR-1 WYARFAAQVMT-DPAYHNMIVKDALSSPSLVRVLDGINSCLPDLPVDVRV
Mflv_2416|M.gilvum_PYR-GCK WYARFAAQVMT-DPAYHNMIVKDALSSPSLVRVLDGINGCLPDLPVDVRV
MMAR_4764|M.marinum_M WYARFAAQAMT-DPAYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRY
MUL_0335|M.ulcerans_Agy99 WYARFAAQAMT-DPAYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRY
MAV_0887|M.avium_104 WYARFAAQAMT-DPAYYNIIVKGALSSPSLVQVVEGINRCLPDLPAEVHF
MSMEG_4858|M.smegmatis_MC2_155 WYARFAAQVMT-DPAYHNIIVRDALSSPSLVQVIEGMNNCLPDLPAEIRA
TH_2278|M.thermoresistible__bu WYARFAAQALA-DPAYQKIVVKDALASPALVRVVEGITRCLPDLPAAVVV
MAB_0835c|M.abscessus_ATCC_199 WLSTLGKLLISGHPALIPMSVSFQPQAARLQELILRLRPDATLPSIRFGV
* : :. :: .** : * :. * .:: : . . .
Mvan_4236|M.vanbaalenii_PYR-1 ERNIMGRNLLMHSCADRERLLAQGAPVARPSWQAAATGLIDAIIGLWHAP
Mflv_2416|M.gilvum_PYR-GCK ERNIMGRNLLMHSCADRERLLAQGSPVPRGSWQSAATGLIDAIIGLWHAP
MMAR_4764|M.marinum_M ERNLMARNLLMHTCADLERALAAGTSVPRPSWREAATGLIDAITGLWLAP
MUL_0335|M.ulcerans_Agy99 ERNLMARNLLMHTCADLERALAAGTSVPRPFWREAATGQIDAITGLWLAP
MAV_0887|M.avium_104 ERNIMARNLLMHTCADRERALAAGTSTSHRSWRAAASGLIDAIVGLWLAP
MSMEG_4858|M.smegmatis_MC2_155 ERNIMARNLLMHSCAERERALAQGAPVPRSSWQGAASGLIDAIVGLWLAP
TH_2278|M.thermoresistible__bu ERNIMARNLLMHTCADFERAFAEGDPVPRASWQAVGNGLIDAIVGLWRAP
MAB_0835c|M.abscessus_ATCC_199 THAVTLTCVVLGDIAHTNRLMSLSGTYLDD--GQMNAQLIDMVTAILAGP
: : ::: *. :* :: . . ** : .: .*
Mvan_4236|M.vanbaalenii_PYR-1 VTEPA-
Mflv_2416|M.gilvum_PYR-GCK VTERP-
MMAR_4764|M.marinum_M VTARE-
MUL_0335|M.ulcerans_Agy99 VTARE-
MAV_0887|M.avium_104 VTPYE-
MSMEG_4858|M.smegmatis_MC2_155 VTGEDR
TH_2278|M.thermoresistible__bu VTEPPQ
MAB_0835c|M.abscessus_ATCC_199 PDES--