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VRYQVTVDAGKAADGRRRQVRRRYRTENEAREGLAKITGGVVEGSFVARSALTVEQACRDWLAGMHDIEP TTRAAYTHALKPLRERHGDMAVQQLTKSHLDQLVTDLTTGKLDGQKRAWTANSINPMLNLVSRVLADLVR QGALARDVAAFVKRLKRPESKLTTFTEEEVRQLLKHVENDRLGHAWHLALAGLRRGEICGLEWADVQLDD DRDAGTLTVAHNRVSVGGRVHEKAPKTVRSARTLPLTPTLARMLKRAKALQAAERLRLGPHYLGDGVRVV VDDSGRPYHPDTLSDFWRELCGDAKVRRIRLHDARHSCASLMHAQGVPIAVISAWLGHADPAFTMRTYVH AENDALNLAAASLQKVVTPS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0698 | - | - | 100% (370) | site-specific recombinase, phage integrase family protein |
| M. avium 104 | MAV_0253 | - | 2e-69 | 41.33% (375) | site-specific recombinase, phage integrase family protein |
| M. avium 104 | MAV_2266 | - | 2e-15 | 26.94% (360) | phage-related integrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3777 | - | 6e-05 | 37.10% (62) | putative integrase (fragment) |
| M. gilvum PYR-GCK | Mflv_2786 | - | 2e-43 | 31.88% (436) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv3751 | - | 7e-05 | 37.10% (62) | integrase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1723 | - | 3e-17 | 25.68% (366) | putative phage integrase |
| M. marinum M | MMAR_3950 | - | 5e-15 | 24.44% (401) | phage-related integrase |
| M. smegmatis MC2 155 | MSMEG_5754 | - | 3e-73 | 43.34% (383) | gp41 protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0529 | - | 4e-12 | 24.92% (301) | prophage integrase |
| M. vanbaalenii PYR-1 | Mvan_3747 | - | 5e-43 | 31.88% (436) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 --------------------------------MAGNTPRGIRKRLNAAGE
MAV_0698|M.avium_104 --------------------------------------------------
MSMEG_5754|M.smegmatis_MC2_155 ----------------------------------------MLQRMARIPD
Mflv_2786|M.gilvum_PYR-GCK ----------MQATTVQTPAGAWMTTTDKPPPKRTRRTEPITRRNAKNGA
Mvan_3747|M.vanbaalenii_PYR-1 ----------MQATTVQTPAGAWMTTTDKPPPKRTRRTEPIMRRNAKNGA
MAB_1723|M.abscessus_ATCC_1997 MEQTERVKKRPACKCKHVYFAHPNEGPCNQCGDCPKYRERERRERGEGGL
MMAR_3950|M.marinum_M ------------------------------------MSSTKRRAPGEGGL
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 PRYQVRYLIRD--------PDAPSGWVETSATFPTLREAKAFKSERDNEA
MAV_0698|M.avium_104 MRYQVTVDAG---------KAADGRRRQVRRRYRTENEAREGLAKITGGV
MSMEG_5754|M.smegmatis_MC2_155 YVKVIDLDSGRRYEVRPEVTGADGKRRQKRERFKTLKEAVDHYTAIAGDR
Mflv_2786|M.gilvum_PYR-GCK VSYTFQVDVG---------THADGTRDRQRFTFSTFAEARREYRKISTEV
Mvan_3747|M.vanbaalenii_PYR-1 VSYTFQVDVG---------THADGTRDRQRFTFSTFAEARREYRKISTEV
MAB_1723|M.abscessus_ATCC_1997 FQRADGMWVGS-----VEVPSEDGLRRRQTVSAKDKGVALDKLRDLRSAI
MMAR_3950|M.marinum_M FKRADGMWTGS-----VDYSTGDGQRRQKRVYSKNRNEAKRKLDELKAEL
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 ALGARRFDPRLGRTPLSRIWTQFSDSKKPAVSPKTWSGYNQHWELRIKPR
MAV_0698|M.avium_104 VEGSFVARSALTVEQACRDWLA----GMHDIEPTTRAAYTHALKP-LRER
MSMEG_5754|M.smegmatis_MC2_155 GRGVHVAPSELTVEDAVDSWLL----GQR-IRPKTMSAYITSLRP-IVDH
Mflv_2786|M.gilvum_PYR-GCK AAGTFVKRDLTTVAEYLARWLD----GRRDVRVNTLAGYRHSLKP-VIDN
Mvan_3747|M.vanbaalenii_PYR-1 AAGTFVKRDLTTVAEYLGRWLD----GRRDVRVNTLAGYRHSLKP-VIDN
MAB_1723|M.abscessus_ATCC_1997 RSGKSPTSSKVHLEQWLNHWLETIQ--KPRVRPTTYKYYETTVRLYILPF
MMAR_3950|M.marinum_M AKGIIPVSSTTTAAVWLRYWVDEIK--KPKVRPNTYDWYEEAIRLHILPN
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 FG-HVPVDEITRADVRAFVDG-----------------------------
MAV_0698|M.avium_104 HG-DMAVQQLTKSHLDQLVTD-----------------------LTTG--
MSMEG_5754|M.smegmatis_MC2_155 LG-KRTVQSITKDDLEQVVQA-----------------------LRAGTS
Mflv_2786|M.gilvum_PYR-GCK LG-GLGLQQLRTSDIDALVTLRLNGTPISQRERRGRRAAEVLAYLRSRSG
Mvan_3747|M.vanbaalenii_PYR-1 LG-GLGLQQLRTSDIDALVTLRLNGTPISQRERRGRRAAEVLAYLRSRSG
MAB_1723|M.abscessus_ATCC_1997 IDGRTQLGKLTPAQVRKMIAKNGTR-------------------------
MMAR_3950|M.marinum_M INSKLKLKQLTPSDIRRMLDQIETSG------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 ---------------------LTVG-------------------------
MAV_0698|M.avium_104 ---------KLDGQKR----AWTAN-------------------------
MSMEG_5754|M.smegmatis_MC2_155 KMGTWNAPTKLTKAAKKVRSPWAAS-------------------------
Mflv_2786|M.gilvum_PYR-GCK GAQYADVRDELGNPGVKALDRLVASGEVIRPSRGRYVAVRDSDPVQSKIP
Mvan_3747|M.vanbaalenii_PYR-1 GAQYADVRDELGNPGVKALDRLVASGEVIRPSRGRYVAVRDSDPVQSKIP
MAB_1723|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3950|M.marinum_M --------------------------------------------------
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 ----PWAKVSTLRLLRSILDVAHQDGRIHRNPALGVSAGRI-PERERHRY
MAV_0698|M.avium_104 ------SINPMLNLVSRVLADLVRQGALARDVAAFVKRLKR-PESKLTTF
MSMEG_5754|M.smegmatis_MC2_155 ------SINPMLARTRSIFEDLVNQGVVVRNVAALVKPLATDTEKTMNTL
Mflv_2786|M.gilvum_PYR-GCK GNVSSRTVVTMLVVLSSALDDAMREGLVARNVARLVKRPAV-EHHEMATW
Mvan_3747|M.vanbaalenii_PYR-1 GNVSSRTVVTMLVVLSSALDDAMREGLVARNVARLVKRPAV-EHHEMATW
MAB_1723|M.abscessus_ATCC_1997 ------NAQKAHQTLVKALGDAMDEGMLDKNVAAVVDKPKHVAIERQPFT
MMAR_3950|M.marinum_M ------NRQRAHKTLKVALKAAVTEGIIVRNVADAVDTPGHVKRSRGSLG
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 LTAQEVRMLATACGDQG---------DVVTILAYTGLRWSEPVGLRVKDI
MAV_0698|M.avium_104 TEEEVRQLLKHVENDRL---------GHAWHLALAGLRRGEICGLEWADV
MSMEG_5754|M.smegmatis_MC2_155 NAEQVTQLLAVTDSHCY---------GIAWRLAVLGLRRGEILALRWDAV
Mflv_2786|M.gilvum_PYR-GCK TAEQAVRFREHVRGDRL---------AACWLLTLAGLRRSEVLGLRWSDV
Mvan_3747|M.vanbaalenii_PYR-1 TAEQAVRFREHVRGDRL---------AACWLLTLAGLRRSEVLGLRWSDV
MAB_1723|M.abscessus_ATCC_1997 FDEARQIIATAIKRNDP-------WATMWAAMFFTGARQGEIIGMEWDRC
MMAR_3950|M.marinum_M APAAKLVIRTAIELQESRDETAPLLATRWATAFLTGARPAELLGLEWDRV
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 DLT----ARRLYVRRAAP--------------------------------
MAV_0698|M.avium_104 QLDDDRDAGTLTVAHNRV--------------------------------
MSMEG_5754|M.smegmatis_MC2_155 DFD----AGTLAISAARL--------------------------------
Mflv_2786|M.gilvum_PYR-GCK DLD----GGTVTIAQGRV--------------------------------
Mvan_3747|M.vanbaalenii_PYR-1 DLD----GGTVTIAQGRV--------------------------------
MAB_1723|M.abscessus_ATCC_1997 DLEKGLFDFSWQLQQLPP-----------ELPRG----------------
MMAR_3950|M.marinum_M DFDNAVFDLSWQLQQLDKTHGCGDPDTNRQYPCGKKRPSFCPAAHWDFND
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
Rv3751|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0529|M.ulcerans_Agy99 ----EVEG-HIVIGPPKTRAGIRTVPLPQVVVDIFKGRITGQAPDQPAV-
MAV_0698|M.avium_104 ----SVGG-RVHEKAPKTVRSARTLPLTPTLARMLKRAKALQAAERLRLG
MSMEG_5754|M.smegmatis_MC2_155 ----ATAG-GATTGAPKTKTSVRTLPMPEDLTAALRRVRKRQKEYRLKLG
Mflv_2786|M.gilvum_PYR-GCK ----VAEGQGTITGDPKSKRSRRALPMPAEVLAALRAFRLRQSEERLAIG
Mvan_3747|M.vanbaalenii_PYR-1 ----VAEGQGTITGDPKSKRSRRALPMPAEVLAALRVFRLRQSEERLAIG
MAB_1723|M.abscessus_ATCC_1997 -FKHRPCHLSLAWTKPKTKAGARVAPMTKPLQAIMEAY-AKTDTGPNPHG
MMAR_3950|M.marinum_M DFIYRECIGSFVWTKPKTSAGTRIVPIVPPLLAMLEQHRSDTAADENPHG
Mb3777|M.bovis_AF2122/97 -------------------------------MKRAKVQQITPHDLRHTAA
Rv3751|M.tuberculosis_H37Rv -------------------------------MKRAKVQQITPHDLRHTAA
MUL_0529|M.ulcerans_Agy99 ---------TSTNGAMLRSNNWRRHTHWNKALKSTDLAPLTIHDLRHTYA
MAV_0698|M.avium_104 PHYLGDGVRVVVDDSGRPYHPDTLSDFWRELCGDAKVRRIRLHDARHSCA
MSMEG_5754|M.smegmatis_MC2_155 SKWTDSGY-VVVDEFGVAPYPDTLTAAWRKTLANAGLPHVRLHDARHSCA
Mflv_2786|M.gilvum_PYR-GCK SEYPDTGL-VAVNVIGLPIRPETYSGEFMRHAKDAGVPLIRLHDVRHTAA
Mvan_3747|M.vanbaalenii_PYR-1 SEYPDTGL-VAVNVIGLPIRPETYSGEFMRHAKDAGVPLIRLHDVRHTAA
MAB_1723|M.abscessus_ATCC_1997 --------LVWRHPDGHPISPTDASDAWRALVKAADVPYRSMHSARHTTA
MMAR_3950|M.marinum_M --------LVWHRRDGRPLSKRDDAQAWRAVLTAAGLPRLEVYTTRHTAS
: : : **: :
Mb3777|M.bovis_AF2122/97 SLAVSAGVNVLALQRILGHKSAKVTLDTYADLFDADLDAVAV--------
Rv3751|M.tuberculosis_H37Rv SLAVSAGVNVLALQRILGHKSAKVTLDTYADLFDADLDAVAV--------
MUL_0529|M.ulcerans_Agy99 SLARKSGADLRYVQKTMGHSTPTVTANIYSDLYADELDQVATNLDQLHAT
MAV_0698|M.avium_104 SLMHAQGVPIAVISAWLGHADPAFTMRTYVHAENDALNLAAASLQK----
MSMEG_5754|M.smegmatis_MC2_155 TLMHLSGVPTVVIAAWLGHQDPGFTLRTYAHSNHDALADAAAMLGS----
Mflv_2786|M.gilvum_PYR-GCK TMLLDRGTTPSATAKWLGH-DPAITLRVYGHVYDGALAAAGDTLLR----
Mvan_3747|M.vanbaalenii_PYR-1 TMLLDRGTTPSATAKWLGH-DPAITLRVYGHVYDGALAAAGDTLLR----
MAB_1723|M.abscessus_ATCC_1997 TLLNNAGVSQETRMKVVGH-SSAVAQQIYVHVDHEPARAALSNLN-----
MMAR_3950|M.marinum_M TLLQELGIPEEVRMQITGH-SSAAAHAAYIHVDQTQTRAALGKLER----
:: * ** . : * . .
Mb3777|M.bovis_AF2122/97 -----TLGKDADQQT-----
Rv3751|M.tuberculosis_H37Rv -----TLGKDADQQT-----
MUL_0529|M.ulcerans_Agy99 EIQTPTTGQEPDEPNQPSSA
MAV_0698|M.avium_104 ----VVTPS-----------
MSMEG_5754|M.smegmatis_MC2_155 ----ITTGKKKEAK------
Mflv_2786|M.gilvum_PYR-GCK ----GH--------------
Mvan_3747|M.vanbaalenii_PYR-1 ----GH--------------
MAB_1723|M.abscessus_ATCC_1997 ----ELLS------------
MMAR_3950|M.marinum_M ----VLLS------------